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Volumn 52, Issue 3, 2017, Pages 265-275

Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis

Author keywords

Colorectal neoplasms; Drug therapy; Immunology; Microbiology; Personalized therapy

Indexed keywords

CONCEPTUAL FRAMEWORK; HEALTH SCIENCE; HUMAN; IMMUNOLOGY; MEDICAL RESEARCH; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; MOLECULAR PATHOLOGICAL EPIDEMIOLOGY; MOLECULAR PATHOLOGY; PERSONALIZED MEDICINE; PHARMACOEPIDEMIOLOGY; PRIORITY JOURNAL; REVIEW; COLORECTAL TUMOR; DISEASES; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE ENVIRONMENT INTERACTION; IMMUNITY; PROCEDURES; TRENDS;

EID: 84991056295     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-016-1272-3     Document Type: Review
Times cited : (85)

References (151)
  • 1
    • 77949928737 scopus 로고    scopus 로고
    • Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology
    • PID: 20208016
    • Ogino S, Stampfer M. Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology. J Natl Cancer Inst. 2010;102:365–7.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 365-367
    • Ogino, S.1    Stampfer, M.2
  • 2
    • 79851511414 scopus 로고    scopus 로고
    • Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field
    • PID: 21036793
    • Ogino S, Chan AT, Fuchs CS, et al. Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut. 2011;60:397–411.
    • (2011) Gut , vol.60 , pp. 397-411
    • Ogino, S.1    Chan, A.T.2    Fuchs, C.S.3
  • 3
    • 84959307169 scopus 로고    scopus 로고
    • Review article: the role of molecular pathological epidemiology in the study of neoplastic and non-neoplastic diseases in the era of precision medicine
    • PID: 26928707
    • Ogino S, Nishihara R, VanderWeele TJ, et al. Review article: the role of molecular pathological epidemiology in the study of neoplastic and non-neoplastic diseases in the era of precision medicine. Epidemiology. 2016;27:602–11.
    • (2016) Epidemiology , vol.27 , pp. 602-611
    • Ogino, S.1    Nishihara, R.2    VanderWeele, T.J.3
  • 4
    • 84947029052 scopus 로고    scopus 로고
    • Molecular pathological epidemiology gives clues to paradoxical findings
    • COI: 1:CAS:528:DC%2BC2MXhs1CnsLnM, PID: 26445996
    • Nishihara R, VanderWeele TJ, Shibuya K, et al. Molecular pathological epidemiology gives clues to paradoxical findings. Eur J Epidemiol. 2015;30:1129–35.
    • (2015) Eur J Epidemiol , vol.30 , pp. 1129-1135
    • Nishihara, R.1    VanderWeele, T.J.2    Shibuya, K.3
  • 5
    • 84876470674 scopus 로고    scopus 로고
    • Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease
    • COI: 1:CAS:528:DC%2BC3sXltFCiu7g%3D, PID: 23307060
    • Ogino S, Lochhead P, Chan AT, et al. Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol. 2013;26:465–84.
    • (2013) Mod Pathol , vol.26 , pp. 465-484
    • Ogino, S.1    Lochhead, P.2    Chan, A.T.3
  • 6
    • 84864579906 scopus 로고    scopus 로고
    • How many molecular subtypes? Implications of the unique tumor principle in personalized medicine
    • COI: 1:CAS:528:DC%2BC38XhtFWjsrfM, PID: 22845482
    • Ogino S, Fuchs CS, Giovannucci E. How many molecular subtypes? Implications of the unique tumor principle in personalized medicine. Expert Rev Mol Diagn. 2012;12:621–8.
    • (2012) Expert Rev Mol Diagn. , vol.12 , pp. 621-628
    • Ogino, S.1    Fuchs, C.S.2    Giovannucci, E.3
  • 7
    • 84864620084 scopus 로고    scopus 로고
    • Commentary: lifestyle factors and colorectal cancer microsatellite instability–molecular pathological epidemiology science, based on unique tumour principle
    • PID: 22596930
    • Ogino S, Giovannucci E. Commentary: lifestyle factors and colorectal cancer microsatellite instability–molecular pathological epidemiology science, based on unique tumour principle. Int J Epidemiol. 2012;41:1072–4.
    • (2012) Int J Epidemiol , vol.41 , pp. 1072-1074
    • Ogino, S.1    Giovannucci, E.2
  • 8
    • 84902189509 scopus 로고    scopus 로고
    • Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology
    • COI: 1:CAS:528:DC%2BC3sXpvVylsL8%3D, PID: 23792451
    • Ogino S, Lochhead P, Giovannucci E, et al. Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology. Oncogene. 2014;33:2949–55.
    • (2014) Oncogene , vol.33 , pp. 2949-2955
    • Ogino, S.1    Lochhead, P.2    Giovannucci, E.3
  • 9
    • 84977530534 scopus 로고    scopus 로고
    • Susceptibility to human cancer: from the perspective of a pathologist
    • PID: 27216305
    • Sugimura H. Susceptibility to human cancer: from the perspective of a pathologist. Pathol Int. 2016;66:359–68.
    • (2016) Pathol Int , vol.66 , pp. 359-368
    • Sugimura, H.1
  • 10
    • 84983734679 scopus 로고    scopus 로고
    • Expression pattern and clinicopathological relevance of the indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase protein in colorectal cancer
    • PID: 27578919
    • Chen IC, Lee KH, Hsu YH, et al. Expression pattern and clinicopathological relevance of the indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase protein in colorectal cancer. Dis Markers. 2016;2016:8169724.
    • (2016) Dis Markers , vol.2016 , pp. 8169724
    • Chen, I.C.1    Lee, K.H.2    Hsu, Y.H.3
  • 11
    • 84984994003 scopus 로고    scopus 로고
    • Aspirin in pancreatic cancer: chemopreventive effects and therapeutic potentials
    • COI: 1:CAS:528:DC%2BC28XhsVWksLjF, PID: 27567928
    • Jiang MJ, Dai JJ, Gu DN, et al. Aspirin in pancreatic cancer: chemopreventive effects and therapeutic potentials. Biochim Biophys Acta. 2016;1866:163–76.
    • (2016) Biochim Biophys Acta , vol.1866 , pp. 163-176
    • Jiang, M.J.1    Dai, J.J.2    Gu, D.N.3
  • 12
    • 84960889352 scopus 로고    scopus 로고
    • Association of Fusobacterium nucleatum infection with colorectal cancer in Chinese patients
    • COI: 1:CAS:528:DC%2BC28XitFGktrnL, PID: 27004000
    • Li YY, Ge QX, Cao J, et al. Association of Fusobacterium nucleatum infection with colorectal cancer in Chinese patients. World J Gastroenterol. 2016;22:3227–33.
    • (2016) World J Gastroenterol , vol.22 , pp. 3227-3233
    • Li, Y.Y.1    Ge, Q.X.2    Cao, J.3
  • 13
    • 84959893858 scopus 로고    scopus 로고
    • Mismatch repair and colon cancer: mechanisms and therapies explored
    • COI: 1:CAS:528:DC%2BC28Xjs1yisL8%3D, PID: 26970951
    • Li SK, Martin A. Mismatch repair and colon cancer: mechanisms and therapies explored. Trends Mol Med. 2016;22:274–89.
    • (2016) Trends Mol Med. , vol.22 , pp. 274-289
    • Li, S.K.1    Martin, A.2
  • 14
    • 84961211571 scopus 로고    scopus 로고
    • Clinical proteomics-driven precision medicine for targeted cancer therapy: current overview and future perspectives
    • COI: 1:CAS:528:DC%2BC28XksVynsbw%3D, PID: 26923776
    • Zhou L, Wang K, Li Q, et al. Clinical proteomics-driven precision medicine for targeted cancer therapy: current overview and future perspectives. Expert Rev Proteomics. 2016;13:367–81.
    • (2016) Expert Rev Proteomics. , vol.13 , pp. 367-381
    • Zhou, L.1    Wang, K.2    Li, Q.3
  • 15
    • 84959466627 scopus 로고    scopus 로고
    • Colorectal cancer: epidemiology, disease mechanisms and interventions to reduce onset and mortality
    • PID: 26964802
    • Aran V, Victorino AP, Thuler LC, et al. Colorectal cancer: epidemiology, disease mechanisms and interventions to reduce onset and mortality. Clin Colorectal Cancer. 2016;15:195–203.
    • (2016) Clin Colorectal Cancer. , vol.15 , pp. 195-203
    • Aran, V.1    Victorino, A.P.2    Thuler, L.C.3
  • 16
    • 84954505134 scopus 로고    scopus 로고
    • FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin
    • COI: 1:CAS:528:DC%2BC28Xos1Ggtg%3D%3D, PID: 26759270
    • Wang S, Wu S, Meng Q, et al. FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin. Sci Rep. 2016;6:19229.
    • (2016) Sci Rep. , vol.6 , pp. 19229
    • Wang, S.1    Wu, S.2    Meng, Q.3
  • 17
    • 85006980125 scopus 로고    scopus 로고
    • SNP rs16906252C > T is an expression and methylation quantitative trait locus associated with an increased risk of developing MGMT-methylated colorectal cancer
    • Kuroiwa-Trzmielina J, Wang F, Rapkins RW, et al. SNP rs16906252C > T is an expression and methylation quantitative trait locus associated with an increased risk of developing MGMT-methylated colorectal cancer. Clin Cancer Res. 2016.
    • (2016) Clin Cancer Res
    • Kuroiwa-Trzmielina, J.1    Wang, F.2    Rapkins, R.W.3
  • 18
    • 85013790721 scopus 로고    scopus 로고
    • Development of a novel scoring system for predicting the risk of colorectal neoplasia: a retrospective study
    • PID: 27284907
    • Ohno T, Adachi S, Okuno M, et al. Development of a novel scoring system for predicting the risk of colorectal neoplasia: a retrospective study. PLoS ONE. 2016;11:e0157269.
    • (2016) PLoS ONE , vol.11
    • Ohno, T.1    Adachi, S.2    Okuno, M.3
  • 19
    • 84928494099 scopus 로고    scopus 로고
    • Serrated polyps and their alternative pathway to the colorectal cancer: a systematic review
    • PID: 25945086
    • Szylberg L, Janiczek M, Popiel A, et al. Serrated polyps and their alternative pathway to the colorectal cancer: a systematic review. Gastroenterol Res Pract. 2015;2015:573814.
    • (2015) Gastroenterol Res Pract. , vol.2015 , pp. 573814
    • Szylberg, L.1    Janiczek, M.2    Popiel, A.3
  • 20
    • 84937865655 scopus 로고    scopus 로고
    • Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer
    • PID: 26207152
    • Cebola I, Custodio J, Munoz M, et al. Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer. Clin Epigenetics. 2015;7:74.
    • (2015) Clin Epigenetics. , vol.7 , pp. 74
    • Cebola, I.1    Custodio, J.2    Munoz, M.3
  • 21
    • 84950150848 scopus 로고    scopus 로고
    • Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations
    • PID: 26530529
    • Li W, Qiu T, Ling Y, et al. Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations. Oncotarget. 2015;6:39607–13.
    • (2015) Oncotarget. , vol.6 , pp. 39607-39613
    • Li, W.1    Qiu, T.2    Ling, Y.3
  • 22
    • 84927938690 scopus 로고    scopus 로고
    • Associations between environmental exposures and incident colorectal cancer by ESR2 protein expression level in a population-based cohort of older women
    • COI: 1:CAS:528:DC%2BC2MXmtVagurY%3D, PID: 25650184
    • Tillmans LS, Vierkant RA, Wang AH, et al. Associations between environmental exposures and incident colorectal cancer by ESR2 protein expression level in a population-based cohort of older women. Cancer Epidemiol Biomarkers Prev. 2015;24:713–9.
    • (2015) Cancer Epidemiol Biomarkers Prev. , vol.24 , pp. 713-719
    • Tillmans, L.S.1    Vierkant, R.A.2    Wang, A.H.3
  • 23
    • 84931046621 scopus 로고    scopus 로고
    • Molecular backgrounds of ERAP1 downregulation in cervical carcinoma
    • PID: 26146606
    • Mehta AM, Osse M, Kolkman-Uljee S, et al. Molecular backgrounds of ERAP1 downregulation in cervical carcinoma. Anal Cell Pathol (Amst). 2015;2015:367837.
    • (2015) Anal Cell Pathol (Amst). , vol.2015 , pp. 367837
    • Mehta, A.M.1    Osse, M.2    Kolkman-Uljee, S.3
  • 24
    • 84901499648 scopus 로고    scopus 로고
    • Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention
    • PID: 24876728
    • Bishehsari F, Mahdavinia M, Vacca M, et al. Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention. World J Gastroenterol. 2014;20:6055–72.
    • (2014) World J Gastroenterol , vol.20 , pp. 6055-6072
    • Bishehsari, F.1    Mahdavinia, M.2    Vacca, M.3
  • 25
    • 84919327167 scopus 로고    scopus 로고
    • Establishment of the cancer prevention study II nutrition cohort colorectal tissue repository
    • COI: 1:CAS:528:DC%2BC2cXitVGrsr%2FF, PID: 25472679
    • Campbell PT, Deka A, Briggs P, et al. Establishment of the cancer prevention study II nutrition cohort colorectal tissue repository. Cancer Epidemiol Biomarkers Prev. 2014;23:2694–702.
    • (2014) Cancer Epidemiol Biomarkers Prev. , vol.23 , pp. 2694-2702
    • Campbell, P.T.1    Deka, A.2    Briggs, P.3
  • 26
    • 84876075247 scopus 로고    scopus 로고
    • Molecular pathways and cellular metabolism in colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXhtVGlt73I, PID: 23595116
    • Hagland HR, Berg M, Jolma IW, et al. Molecular pathways and cellular metabolism in colorectal cancer. Dig Surg. 2013;30:12–25.
    • (2013) Dig Surg. , vol.30 , pp. 12-25
    • Hagland, H.R.1    Berg, M.2    Jolma, I.W.3
  • 27
    • 84877931368 scopus 로고    scopus 로고
    • Family history of colorectal cancer in BRAF p. V600E-mutated colorectal cancer cases
    • COI: 1:CAS:528:DC%2BC3sXntlShtb4%3D, PID: 23462926
    • Buchanan DD, Win AK, Walsh MD, et al. Family history of colorectal cancer in BRAF p. V600E-mutated colorectal cancer cases. Cancer Epidemiol Biomarkers Prev. 2013;22:917–26.
    • (2013) Cancer Epidemiol Biomarkers Prev. , vol.22 , pp. 917-926
    • Buchanan, D.D.1    Win, A.K.2    Walsh, M.D.3
  • 28
    • 84867101876 scopus 로고    scopus 로고
    • Aspirin as adjuvant therapy for colorectal cancer–reinterpreting paradigms
    • COI: 1:CAS:528:DC%2BC38XhsVartr%2FE, PID: 22910681
    • Chia WK, Ali R, Toh HC. Aspirin as adjuvant therapy for colorectal cancer–reinterpreting paradigms. Nat Rev Clin Oncol. 2012;9:561–70.
    • (2012) Nat Rev Clin Oncol. , vol.9 , pp. 561-570
    • Chia, W.K.1    Ali, R.2    Toh, H.C.3
  • 29
    • 81255179895 scopus 로고    scopus 로고
    • The CpG island methylator phenotype in colorectal cancer: progress and problems
    • COI: 1:CAS:528:DC%2BC3MXhs1Cju7zP, PID: 22056543
    • Hughes LA, Khalid-de Bakker CA, Smits KM, et al. The CpG island methylator phenotype in colorectal cancer: progress and problems. Biochim Biophys Acta. 2012;1825:77–85.
    • (2012) Biochim Biophys Acta , vol.1825 , pp. 77-85
    • Hughes, L.A.1    Khalid-de Bakker, C.A.2    Smits, K.M.3
  • 30
    • 80052929478 scopus 로고    scopus 로고
    • CpG island methylation in colorectal cancer: past, present and future
    • PID: 21559209
    • Curtin K, Slattery ML, Samowitz WS. CpG island methylation in colorectal cancer: past, present and future. Patholog Res Int. 2011;2011:902674.
    • (2011) Patholog Res Int. , vol.2011 , pp. 902674
    • Curtin, K.1    Slattery, M.L.2    Samowitz, W.S.3
  • 31
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • COI: 1:CAS:528:DC%2BC2MXjvFGnsLY%3D, PID: 25635347
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015;372:793–5.
    • (2015) N Engl J Med , vol.372 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 32
    • 84978137128 scopus 로고    scopus 로고
    • Biomarker tests for molecularly targeted therapies-the key to unlocking precision medicine
    • PID: 27353537
    • Lyman GH, Moses HL. Biomarker tests for molecularly targeted therapies-the key to unlocking precision medicine. N Engl J Med. 2016;375:4–6.
    • (2016) N Engl J Med , vol.375 , pp. 4-6
    • Lyman, G.H.1    Moses, H.L.2
  • 33
    • 84890073749 scopus 로고    scopus 로고
    • The role of epidemiology in the era of molecular epidemiology and genomics: summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium
    • PID: 24105654
    • Kuller LH, Bracken MB, Ogino S, et al. The role of epidemiology in the era of molecular epidemiology and genomics: summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium. Am J Epidemiol. 2013;178:1350–4.
    • (2013) Am J Epidemiol , vol.178 , pp. 1350-1354
    • Kuller, L.H.1    Bracken, M.B.2    Ogino, S.3
  • 34
    • 84920171764 scopus 로고    scopus 로고
    • Challenges and opportunities in international molecular cancer prevention research: an ASPO molecular epidemiology and the environment and international cancer prevention interest groups report
    • PID: 25277796
    • Epplein M, Bostick RM, Mu L, et al. Challenges and opportunities in international molecular cancer prevention research: an ASPO molecular epidemiology and the environment and international cancer prevention interest groups report. Cancer Epidemiol Biomarkers Prev. 2014;23:2613–7.
    • (2014) Cancer Epidemiol Biomarkers Prev. , vol.23 , pp. 2613-2617
    • Epplein, M.1    Bostick, R.M.2    Mu, L.3
  • 35
    • 85013815105 scopus 로고    scopus 로고
    • Ogino S. Molecular pathological epidemiology (MPE): overview of its paradigm and wide applicability even without tumor tissue [abstract]. In:. National Harbor, MD: Cancer Prev Res (Phila);6:CN06-01
    • Ogino S. Molecular pathological epidemiology (MPE): overview of its paradigm and wide applicability even without tumor tissue [abstract]. In: Proceedings of the twelfth annual AACR international conference on frontiers in cancer prevention research; 2013 Oct 27–30. National Harbor, MD: Cancer Prev Res (Phila); 2013;6:CN06-01.
    • (2013) Proceedings of the twelfth annual AACR international conference on frontiers in cancer prevention research; 2013 Oct 27–30
  • 36
    • 84930931584 scopus 로고    scopus 로고
    • Proceedings of the second international molecular pathological epidemiology (MPE) meeting
    • PID: 25956270
    • Ogino S, Campbell PT, Nishihara R, et al. Proceedings of the second international molecular pathological epidemiology (MPE) meeting. Cancer Causes Control. 2015;26:959–72.
    • (2015) Cancer Causes Control , vol.26 , pp. 959-972
    • Ogino, S.1    Campbell, P.T.2    Nishihara, R.3
  • 37
    • 84955176253 scopus 로고    scopus 로고
    • Integration of molecular pathology, epidemiology and social science for global precision medicine
    • COI: 1:CAS:528:DC%2BC2MXhvFOqsrfP, PID: 26636627
    • Nishi A, Milner DA Jr, Giovannucci EL, et al. Integration of molecular pathology, epidemiology and social science for global precision medicine. Expert Rev Mol Diagn. 2016;16:11–23.
    • (2016) Expert Rev Mol Diagn. , vol.16 , pp. 11-23
    • Nishi, A.1    Milner, D.A.2    Giovannucci, E.L.3
  • 38
    • 84923001093 scopus 로고    scopus 로고
    • Lifecourse epidemiology and molecular pathological epidemiology
    • PID: 25528613
    • Nishi A, Kawachi I, Koenen KC, et al. Lifecourse epidemiology and molecular pathological epidemiology. Am J Prev Med. 2015;48:116–9.
    • (2015) Am J Prev Med , vol.48 , pp. 116-119
    • Nishi, A.1    Kawachi, I.2    Koenen, K.C.3
  • 39
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • COI: 1:CAS:528:DyaK3cXktlyhtrg%3D, PID: 2188735
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759–67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 40
    • 84922879141 scopus 로고    scopus 로고
    • Association between molecular subtypes of colorectal cancer and patient survival
    • Phipps AI, Limburg PJ, Baron JA, et al. Association between molecular subtypes of colorectal cancer and patient survival. Gastroenterology. 2015;148(77–87):e2.
    • (2015) Gastroenterology , vol.148 , Issue.77-87
    • Phipps, A.I.1    Limburg, P.J.2    Baron, J.A.3
  • 42
    • 84955408177 scopus 로고    scopus 로고
    • Obesity and colorectal cancer: molecular features of adipose tissue
    • PID: 26801617
    • Martinez-Useros J, Garcia-Foncillas J. Obesity and colorectal cancer: molecular features of adipose tissue. J Transl Med. 2016;14:21.
    • (2016) J Transl Med. , vol.14 , pp. 21
    • Martinez-Useros, J.1    Garcia-Foncillas, J.2
  • 43
    • 84928379010 scopus 로고    scopus 로고
    • Nutrients, foods, and colorectal cancer prevention
    • Song M, Garrett WS, Chan AT. Nutrients, foods, and colorectal cancer prevention. Gastroenterology. 2015;148(1244–60):e16.
    • (2015) Gastroenterology , vol.148 , Issue.1244-60
    • Song, M.1    Garrett, W.S.2    Chan, A.T.3
  • 44
    • 84982091006 scopus 로고    scopus 로고
    • Colorectal cancer epidemiology in the Nurses’ Health Study
    • PID: 27459444
    • Lee DH, Keum N, Giovannucci EL. Colorectal cancer epidemiology in the Nurses’ Health Study. Am J Public Health. 2016;106:1599–607.
    • (2016) Am J Public Health , vol.106 , pp. 1599-1607
    • Lee, D.H.1    Keum, N.2    Giovannucci, E.L.3
  • 45
    • 84961779011 scopus 로고    scopus 로고
    • Colorectal adenomas
    • COI: 1:CAS:528:DC%2BC28Xht1Gnu7%2FM, PID: 26981936
    • Strum WB. Colorectal adenomas. N Engl J Med. 2016;374:1065–75.
    • (2016) N Engl J Med , vol.374 , pp. 1065-1075
    • Strum, W.B.1
  • 46
    • 84959466627 scopus 로고    scopus 로고
    • Disease Mechanisms and Interventions to Reduce Onset and Mortality, Clin Colorectal Cancer
    • Aran V, Victorino AP, Thuler LC, et al. Colorectal Cancer: Epidemiology, Disease Mechanisms and Interventions to Reduce Onset and Mortality. Clin Colorectal Cancer. 2016.
    • (2016) Colorectal Cancer: Epidemiology
    • Aran, V.1    Victorino, A.P.2    Thuler, L.C.3
  • 47
    • 84905591645 scopus 로고    scopus 로고
    • Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions
    • COI: 1:CAS:528:DC%2BC2cXhtlahsL%2FN, PID: 24935274
    • Lochhead P, Chan AT, Giovannucci E, et al. Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions. Am J Gastroenterol. 2014;109:1205–14.
    • (2014) Am J Gastroenterol , vol.109 , pp. 1205-1214
    • Lochhead, P.1    Chan, A.T.2    Giovannucci, E.3
  • 48
    • 84888589060 scopus 로고    scopus 로고
    • The merits of subtyping obesity: one size does not fit all
    • COI: 1:CAS:528:DC%2BC2cXmtFarsA%3D%3D, PID: 24189835
    • Field AE, Camargo CA Jr, Ogino S. The merits of subtyping obesity: one size does not fit all. JAMA. 2013;310:2147–8.
    • (2013) JAMA , vol.310 , pp. 2147-2148
    • Field, A.E.1    Camargo, C.A.2    Ogino, S.3
  • 49
    • 84889767375 scopus 로고    scopus 로고
    • New insights on bariatric surgery outcomes
    • COI: 1:CAS:528:DC%2BC2cXosFGhsg%3D%3D, PID: 24189645
    • Ikramuddin S, Livingston EH. New insights on bariatric surgery outcomes. JAMA. 2013;310:2401–2.
    • (2013) JAMA , vol.310 , pp. 2401-2402
    • Ikramuddin, S.1    Livingston, E.H.2
  • 50
    • 85013838557 scopus 로고    scopus 로고
    • The importance of gene-environment interactions in human obesity
    • PID: 27503943
    • Reddon H, Gueant JL, Meyre D. The importance of gene-environment interactions in human obesity. Clin Sci (Lond). 2016;130:1571–97.
    • (2016) Clin Sci (Lond). , vol.130 , pp. 1571-1597
    • Reddon, H.1    Gueant, J.L.2    Meyre, D.3
  • 51
    • 84982171757 scopus 로고    scopus 로고
    • Dysregulated immune system networks in war veterans with PTSD is an outcome of altered miRNA expression and DNA methylation
    • COI: 1:CAS:528:DC%2BC28XhtlCit7%2FO, PID: 27510991
    • Bam M, Yang X, Zumbrun EE, et al. Dysregulated immune system networks in war veterans with PTSD is an outcome of altered miRNA expression and DNA methylation. Sci Rep. 2016;6:31209.
    • (2016) Sci Rep. , vol.6 , pp. 31209
    • Bam, M.1    Yang, X.2    Zumbrun, E.E.3
  • 52
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • COI: 1:CAS:528:DC%2BD2sXlvVersr0%3D, PID: 17522398
    • Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med. 2007;356:2131–42.
    • (2007) N Engl J Med , vol.356 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 53
    • 68849123400 scopus 로고    scopus 로고
    • Aspirin use and survival after diagnosis of colorectal cancer
    • COI: 1:CAS:528:DC%2BD1MXpslynu7w%3D, PID: 19671906
    • Chan AT, Ogino S, Fuchs CS. Aspirin use and survival after diagnosis of colorectal cancer. JAMA. 2009;302:649–58.
    • (2009) JAMA , vol.302 , pp. 649-658
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 54
    • 84867817838 scopus 로고    scopus 로고
    • Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival
    • COI: 1:CAS:528:DC%2BC38Xhs1Whsr3K, PID: 23094721
    • Liao X, Lochhead P, Nishihara R, et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med. 2012;367:1596–606.
    • (2012) N Engl J Med , vol.367 , pp. 1596-1606
    • Liao, X.1    Lochhead, P.2    Nishihara, R.3
  • 55
    • 84879028228 scopus 로고    scopus 로고
    • Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXptVOrtbo%3D, PID: 23629521
    • Yamauchi M, Lochhead P, Imamura Y, et al. Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2013;22:1142–52.
    • (2013) Cancer Epidemiol Biomarkers Prev. , vol.22 , pp. 1142-1152
    • Yamauchi, M.1    Lochhead, P.2    Imamura, Y.3
  • 56
    • 84879395305 scopus 로고    scopus 로고
    • Aspirin use and risk of colorectal cancer according to BRAF mutation status
    • COI: 1:CAS:528:DC%2BC3sXhtFOgs7fL, PID: 23800934
    • Nishihara R, Lochhead P, Kuchiba A, et al. Aspirin use and risk of colorectal cancer according to BRAF mutation status. JAMA. 2013;309:2563–71.
    • (2013) JAMA , vol.309 , pp. 2563-2571
    • Nishihara, R.1    Lochhead, P.2    Kuchiba, A.3
  • 57
    • 84876484863 scopus 로고    scopus 로고
    • A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification
    • PID: 23788674
    • Nishihara R, Morikawa T, Kuchiba A, et al. A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification. Am J Epidemiol. 2013;178:84–100.
    • (2013) Am J Epidemiol , vol.178 , pp. 84-100
    • Nishihara, R.1    Morikawa, T.2    Kuchiba, A.3
  • 58
    • 84957842982 scopus 로고    scopus 로고
    • Survival benefit of exercise differs by tumor IRS1 expression status in colorectal cancer
    • PID: 26577117
    • Hanyuda A, Kim SA, Martinez-Fernandez A, et al. Survival benefit of exercise differs by tumor IRS1 expression status in colorectal cancer. Ann Surg Oncol. 2016;23:908–17.
    • (2016) Ann Surg Oncol , vol.23 , pp. 908-917
    • Hanyuda, A.1    Kim, S.A.2    Martinez-Fernandez, A.3
  • 59
    • 85013757961 scopus 로고    scopus 로고
    • Modeling the prevention of colorectal cancer from the combined impact of host and behavioral risk factors, Genet Med
    • Frampton M, Houlston RS. Modeling the prevention of colorectal cancer from the combined impact of host and behavioral risk factors. Genet Med. 2016.
    • (2016) Houlston RS
    • Frampton, M.1
  • 60
    • 84874927068 scopus 로고    scopus 로고
    • Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with beta-catenin (CTNNB1) status
    • COI: 1:CAS:528:DC%2BC3sXjtlKjsrg%3D, PID: 23442321
    • Morikawa T, Kuchiba A, Lochhead P, et al. Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with beta-catenin (CTNNB1) status. Cancer Res. 2013;73:1600–10.
    • (2013) Cancer Res , vol.73 , pp. 1600-1610
    • Morikawa, T.1    Kuchiba, A.2    Lochhead, P.3
  • 61
    • 0030975671 scopus 로고    scopus 로고
    • −/− colon carcinoma
    • COI: 1:CAS:528:DyaK2sXitVGksr8%3D, PID: 9065401
    • −/− colon carcinoma. Science. 1997;275:1784–7.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3
  • 62
    • 79955369630 scopus 로고    scopus 로고
    • Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer
    • COI: 1:CAS:528:DC%2BC3MXlsVyiur4%3D, PID: 21521850
    • Morikawa T, Kuchiba A, Yamauchi M, et al. Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer. JAMA. 2011;305:1685–94.
    • (2011) JAMA , vol.305 , pp. 1685-1694
    • Morikawa, T.1    Kuchiba, A.2    Yamauchi, M.3
  • 63
    • 82555191051 scopus 로고    scopus 로고
    • Cancer immunology–analysis of host and tumor factors for personalized medicine
    • COI: 1:CAS:528:DC%2BC3MXhsFKms7zL, PID: 21826083
    • Ogino S, Galon J, Fuchs CS, et al. Cancer immunology–analysis of host and tumor factors for personalized medicine. Nat Rev Clin Oncol. 2011;8:711–9.
    • (2011) Nat Rev Clin Oncol. , vol.8 , pp. 711-719
    • Ogino, S.1    Galon, J.2    Fuchs, C.S.3
  • 64
    • 84860589077 scopus 로고    scopus 로고
    • Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum
    • COI: 1:CAS:528:DC%2BC38XhtVeis7jK, PID: 22427238
    • Yamauchi M, Morikawa T, Kuchiba A, et al. Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum. Gut. 2012;61:847–54.
    • (2012) Gut , vol.61 , pp. 847-854
    • Yamauchi, M.1    Morikawa, T.2    Kuchiba, A.3
  • 65
    • 84860599697 scopus 로고    scopus 로고
    • Colorectal cancer: a tale of two sides or a continuum?
    • PID: 22490520
    • Yamauchi M, Lochhead P, Morikawa T, et al. Colorectal cancer: a tale of two sides or a continuum? Gut. 2012;61:794–7.
    • (2012) Gut , vol.61 , pp. 794-797
    • Yamauchi, M.1    Lochhead, P.2    Morikawa, T.3
  • 66
    • 84899547782 scopus 로고    scopus 로고
    • Fink SP, Yamauchi M, Nishihara R, et al. Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). 6:233re2
    • Fink SP, Yamauchi M, Nishihara R, et al. Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). Sci Transl Med. 2014;6:233re2.
    • (2014) Sci Transl Med
  • 67
    • 81555195415 scopus 로고    scopus 로고
    • Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies
    • COI: 1:CAS:528:DC%2BC3MXhs1SnsrfJ, PID: 21680706
    • Lee JE, Baba Y, Ng K, et al. Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies. Cancer Prev Res (Phila). 2011;4:1808–15.
    • (2011) Cancer Prev Res (Phila). , vol.4 , pp. 1808-1815
    • Lee, J.E.1    Baba, Y.2    Ng, K.3
  • 68
    • 80052956941 scopus 로고    scopus 로고
    • Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803
    • COI: 1:CAS:528:DC%2BC3MXhtlGrsrrP, PID: 21849660
    • Ng K, Ogino S, Meyerhardt JA, et al. Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803. J Natl Cancer Inst. 2011;103:1540–51.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1540-1551
    • Ng, K.1    Ogino, S.2    Meyerhardt, J.A.3
  • 69
    • 84892843686 scopus 로고    scopus 로고
    • Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXhvF2kur7J, PID: 24062397
    • Domingo E, Church DN, Sieber O, et al. Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer. J Clin Oncol. 2013;31:4297–305.
    • (2013) J Clin Oncol , vol.31 , pp. 4297-4305
    • Domingo, E.1    Church, D.N.2    Sieber, O.3
  • 70
    • 85010679719 scopus 로고    scopus 로고
    • Population-wide impact of long-term use of aspirin and the risk for cancer
    • PID: 26940135
    • Cao Y, Nishihara R, Wu K, et al. Population-wide impact of long-term use of aspirin and the risk for cancer. JAMA Oncol. 2016;2:762–9.
    • (2016) JAMA Oncol. , vol.2 , pp. 762-769
    • Cao, Y.1    Nishihara, R.2    Wu, K.3
  • 71
    • 84959516180 scopus 로고    scopus 로고
    • Aspirin and colorectal cancer: the promise of precision chemoprevention
    • COI: 1:CAS:528:DC%2BC28XisVyru7o%3D, PID: 26868177
    • Drew DA, Cao Y, Chan AT. Aspirin and colorectal cancer: the promise of precision chemoprevention. Nat Rev Cancer. 2016;16:173–86.
    • (2016) Nat Rev Cancer , vol.16 , pp. 173-186
    • Drew, D.A.1    Cao, Y.2    Chan, A.T.3
  • 72
    • 78650215449 scopus 로고    scopus 로고
    • Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
    • COI: 1:CAS:528:DC%2BC3cXhsVGitbfF, PID: 20970847
    • Rothwell PM, Wilson M, Elwin CE, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet. 2010;376:1741–50.
    • (2010) Lancet , vol.376 , pp. 1741-1750
    • Rothwell, P.M.1    Wilson, M.2    Elwin, C.E.3
  • 73
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
    • COI: 1:CAS:528:DC%2BC38XktlGku7c%3D, PID: 22440947
    • Rothwell PM, Wilson M, Price JF, et al. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet. 2012;379:1591–601.
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3
  • 74
    • 84941278479 scopus 로고    scopus 로고
    • Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis
    • COI: 1:CAS:528:DC%2BC28XhtVKku7vP, PID: 25239119
    • Li P, Wu H, Zhang H, et al. Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis. Gut. 2015;64:1419–25.
    • (2015) Gut , vol.64 , pp. 1419-1425
    • Li, P.1    Wu, H.2    Zhang, H.3
  • 75
    • 84940481188 scopus 로고    scopus 로고
    • Low-dose aspirin or nonsteroidal anti-inflammatory drug use and colorectal cancer risk: a population-based. case-control study
    • PID: 26302241
    • Friis S, Riis AH, Erichsen R, et al. Low-dose aspirin or nonsteroidal anti-inflammatory drug use and colorectal cancer risk: a population-based. case-control study. Ann Intern Med. 2015;163:347–55.
    • (2015) Ann Intern Med , vol.163 , pp. 347-355
    • Friis, S.1    Riis, A.H.2    Erichsen, R.3
  • 76
    • 84975292439 scopus 로고    scopus 로고
    • Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: U.S. preventive services task force recommendation statement
    • PID: 27064677
    • Bibbins-Domingo K. Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: U.S. preventive services task force recommendation statement. Ann Intern Med. 2016;164:836–45.
    • (2016) Ann Intern Med , vol.164 , pp. 836-845
    • Bibbins-Domingo, K.1
  • 77
    • 84963553379 scopus 로고    scopus 로고
    • Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma, Cell Rep
    • Giannakis M, Mu XJ, Shukla SA, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016.
    • (2016) et al
    • Giannakis, M.1    Mu, X.J.2    Shukla, S.A.3
  • 78
    • 84873542162 scopus 로고    scopus 로고
    • Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival
    • COI: 1:CAS:528:DC%2BC3sXitlClsro%3D, PID: 23104301
    • Garcia-Albeniz X, Nan H, Valeri L, et al. Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival. Carcinogenesis. 2013;34:292–8.
    • (2013) Carcinogenesis , vol.34 , pp. 292-298
    • Garcia-Albeniz, X.1    Nan, H.2    Valeri, L.3
  • 79
    • 84929390853 scopus 로고    scopus 로고
    • Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants
    • COI: 1:CAS:528:DC%2BC2MXlvVWmsrY%3D, PID: 25781442
    • Nan H, Hutter CM, Lin Y, et al. Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants. JAMA. 2015;313:1133–42.
    • (2015) JAMA , vol.313 , pp. 1133-1142
    • Nan, H.1    Hutter, C.M.2    Lin, Y.3
  • 80
    • 84891449924 scopus 로고    scopus 로고
    • Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations
    • COI: 1:CAS:528:DC%2BC2cXhs1yrsw%3D%3D, PID: 24317174
    • Nan H, Morikawa T, Suuriniemi M, et al. Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. J Natl Cancer Inst. 2013;105:1852–61.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1852-1861
    • Nan, H.1    Morikawa, T.2    Suuriniemi, M.3
  • 81
    • 84940654101 scopus 로고    scopus 로고
    • Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer
    • PID: 26071399
    • Khalili H, Gong J, Brenner H, et al. Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carcinogenesis. 2015;36:999–1007.
    • (2015) Carcinogenesis , vol.36 , pp. 999-1007
    • Khalili, H.1    Gong, J.2    Brenner, H.3
  • 82
    • 84955215661 scopus 로고    scopus 로고
    • CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk
    • COI: 1:CAS:528:DC%2BC28XhtlKrsbc%3D, PID: 26766742
    • Garcia-Albeniz X, Rudolph A, Hutter C, et al. CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk. Br J Cancer. 2016;114:221–9.
    • (2016) Br J Cancer , vol.114 , pp. 221-229
    • Garcia-Albeniz, X.1    Rudolph, A.2    Hutter, C.3
  • 83
    • 29144514645 scopus 로고    scopus 로고
    • Effector memory T cells, early metastasis, and survival in colorectal cancer
    • COI: 1:CAS:528:DC%2BD2MXhtlarsrrE, PID: 16371631
    • Pages F, Berger A, Camus M, et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med. 2005;353:2654–66.
    • (2005) N Engl J Med , vol.353 , pp. 2654-2666
    • Pages, F.1    Berger, A.2    Camus, M.3
  • 84
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • COI: 1:CAS:528:DC%2BD28XhtVSnsrnK, PID: 17008531
    • Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 2006;313:1960–4.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 85
    • 70350225838 scopus 로고    scopus 로고
    • Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype
    • COI: 1:CAS:528:DC%2BD1MXhtlyqsb%2FI, PID: 19825961
    • Ogino S, Nosho K, Irahara N, et al. Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype. Clin Cancer Res. 2009;15:6412–20.
    • (2009) Clin Cancer Res , vol.15 , pp. 6412-6420
    • Ogino, S.1    Nosho, K.2    Irahara, N.3
  • 86
    • 78349277576 scopus 로고    scopus 로고
    • Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review
    • PID: 20927778
    • Nosho K, Baba Y, Tanaka N, et al. Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review. J Pathol. 2010;222:350–66.
    • (2010) J Pathol. , vol.222 , pp. 350-366
    • Nosho, K.1    Baba, Y.2    Tanaka, N.3
  • 87
    • 84920956732 scopus 로고    scopus 로고
    • PD-1 blockade induces responses by inhibiting adaptive immune resistance
    • COI: 1:CAS:528:DC%2BC2cXitFanu7jL, PID: 25428505
    • Tumeh PC, Harview CL, Yearley JH, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature. 2014;515:568–71.
    • (2014) Nature , vol.515 , pp. 568-571
    • Tumeh, P.C.1    Harview, C.L.2    Yearley, J.H.3
  • 88
    • 84927150740 scopus 로고    scopus 로고
    • Immune checkpoint blockade in cancer therapy
    • COI: 1:CAS:528:DC%2BC2MXhsFKmt7%2FN, PID: 25605845
    • Postow MA, Callahan MK, Wolchok JD. Immune checkpoint blockade in cancer therapy. J Clin Oncol. 2015;33:1974–82.
    • (2015) J Clin Oncol , vol.33 , pp. 1974-1982
    • Postow, M.A.1    Callahan, M.K.2    Wolchok, J.D.3
  • 89
    • 84969850678 scopus 로고    scopus 로고
    • Coinhibitory pathways in immunotherapy for cancer
    • PID: 26927206
    • Baumeister SH, Freeman GJ, Dranoff G, et al. Coinhibitory pathways in immunotherapy for cancer. Annu Rev Immunol. 2016;34:539–73.
    • (2016) Annu Rev Immunol , vol.34 , pp. 539-573
    • Baumeister, S.H.1    Freeman, G.J.2    Dranoff, G.3
  • 90
    • 84928062583 scopus 로고    scopus 로고
    • Immune checkpoint blockade: a common denominator approach to cancer therapy
    • COI: 1:CAS:528:DC%2BC2MXmtVaku7k%3D, PID: 25858804
    • Topalian SL, Drake CG, Pardoll DM. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell. 2015;27:450–61.
    • (2015) Cancer Cell , vol.27 , pp. 450-461
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 91
    • 84932628341 scopus 로고    scopus 로고
    • PD-1 blockade in tumors with mismatch-repair deficiency
    • COI: 1:CAS:528:DC%2BC2MXhtFyrsbrI, PID: 26028255
    • Le DT, Uram JN, Wang H, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372:2509–20.
    • (2015) N Engl J Med , vol.372 , pp. 2509-2520
    • Le, D.T.1    Uram, J.N.2    Wang, H.3
  • 92
    • 84960464701 scopus 로고    scopus 로고
    • Immunologic approaches to cancer prevention-current status, challenges, and future perspectives
    • COI: 1:CAS:528:DC%2BC28XhsFKgsLo%3D, PID: 26970135
    • Wojtowicz ME, Dunn BK, Umar A. Immunologic approaches to cancer prevention-current status, challenges, and future perspectives. Semin Oncol. 2016;43:161–72.
    • (2016) Semin Oncol , vol.43 , pp. 161-172
    • Wojtowicz, M.E.1    Dunn, B.K.2    Umar, A.3
  • 93
    • 84954461709 scopus 로고    scopus 로고
    • Cancer immunoprevention
    • COI: 1:CAS:528:DC%2BC28XmvVSqsg%3D%3D, PID: 26799207
    • Finn OJ, Beatty PL. Cancer immunoprevention. Curr Opin Immunol. 2016;39:52–8.
    • (2016) Curr Opin Immunol , vol.39 , pp. 52-58
    • Finn, O.J.1    Beatty, P.L.2
  • 94
    • 85027954904 scopus 로고    scopus 로고
    • Prevention and treatment of cancers by immune modulating nutrients
    • COI: 1:CAS:528:DC%2BC28XjvVyrtr0%3D, PID: 26833775
    • Janakiram NB, Mohammed A, Madka V, et al. Prevention and treatment of cancers by immune modulating nutrients. Mol Nutr Food Res. 2016;60:1275–94.
    • (2016) Mol Nutr Food Res , vol.60 , pp. 1275-1294
    • Janakiram, N.B.1    Mohammed, A.2    Madka, V.3
  • 95
    • 84922369377 scopus 로고    scopus 로고
    • The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints
    • COI: 1:CAS:528:DC%2BC2MXhtFCntbo%3D, PID: 25358689
    • Llosa NJ, Cruise M, Tam A, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov. 2015;5:43–51.
    • (2015) Cancer Discov. , vol.5 , pp. 43-51
    • Llosa, N.J.1    Cruise, M.2    Tam, A.3
  • 96
    • 84938984463 scopus 로고    scopus 로고
    • The prognostic landscape of genes and infiltrating immune cells across human cancers
    • COI: 1:CAS:528:DC%2BC2MXht1WltLnI, PID: 26193342
    • Gentles AJ, Newman AM, Liu CL, et al. The prognostic landscape of genes and infiltrating immune cells across human cancers. Nat Med. 2015;21:938–45.
    • (2015) Nat Med , vol.21 , pp. 938-945
    • Gentles, A.J.1    Newman, A.M.2    Liu, C.L.3
  • 97
    • 84922482206 scopus 로고    scopus 로고
    • Shiels MS, Katki HA, Freedman ND, et al. Cigarette smoking and variations in systemic immune and inflammation markers. 106:dju294
    • Shiels MS, Katki HA, Freedman ND, et al. Cigarette smoking and variations in systemic immune and inflammation markers. J Natl Cancer Inst. 2014;106:dju294.
    • (2014) J Natl Cancer Inst
  • 98
    • 84941419767 scopus 로고    scopus 로고
    • Cyclooxygenase-dependent tumor growth through evasion of immunity
    • COI: 1:CAS:528:DC%2BC2MXhsVKhu7bL, PID: 26343581
    • Zelenay S, van der Veen AG, Bottcher JP, et al. Cyclooxygenase-dependent tumor growth through evasion of immunity. Cell. 2015;162:1257–70.
    • (2015) Cell , vol.162 , pp. 1257-1270
    • Zelenay, S.1    van der Veen, A.G.2    Bottcher, J.P.3
  • 99
    • 84856090985 scopus 로고    scopus 로고
    • Aspirin and immune system
    • COI: 1:CAS:528:DC%2BC38Xht1aht7o%3D, PID: 22172645
    • Hussain M, Javeed A, Ashraf M, et al. Aspirin and immune system. Int Immunopharmacol. 2012;12:10–20.
    • (2012) Int Immunopharmacol , vol.12 , pp. 10-20
    • Hussain, M.1    Javeed, A.2    Ashraf, M.3
  • 100
    • 85024373022 scopus 로고    scopus 로고
    • Tumour CD274 (PD-L1) expression and T cells in colorectal cancer
    • Masugi Y, Nishihara R, Yang J, et al. Tumour CD274 (PD-L1) expression and T cells in colorectal cancer. Gut. 2016.
    • (2016) Gut
    • Masugi, Y.1    Nishihara, R.2    Yang, J.3
  • 101
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • COI: 1:CAS:528:DC%2BC38XhtV2rs7fN, PID: 22658127
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443–54.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 102
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • COI: 1:CAS:528:DC%2BC38XhtV2rsbnJ, PID: 22658128
    • Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455–65.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 103
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • COI: 1:CAS:528:DC%2BC3MXosVegtro%3D, PID: 21639810
    • Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364:2517–26.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 104
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • COI: 1:CAS:528:DC%2BD2MXhvVSru7c%3D, PID: 15711557
    • Muller AJ, DuHadaway JB, Donover PS, et al. Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat Med. 2005;11:312–9.
    • (2005) Nat Med , vol.11 , pp. 312-319
    • Muller, A.J.1    DuHadaway, J.B.2    Donover, P.S.3
  • 105
    • 84888385324 scopus 로고    scopus 로고
    • Immunity, inflammation and cancer: a leading role for adenosine
    • COI: 1:CAS:528:DC%2BC3sXhslKmtrnL, PID: 24226193
    • Antonioli L, Blandizzi C, Pacher P, et al. Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer. 2013;13:842–57.
    • (2013) Nat Rev Cancer , vol.13 , pp. 842-857
    • Antonioli, L.1    Blandizzi, C.2    Pacher, P.3
  • 106
    • 84958863200 scopus 로고    scopus 로고
    • Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status
    • COI: 1:CAS:528:DC%2BC28XmvV2gurw%3D, PID: 25591978
    • Song M, Nishihara R, Wang M, et al. Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status. Gut. 2016;65:296–304.
    • (2016) Gut , vol.65 , pp. 296-304
    • Song, M.1    Nishihara, R.2    Wang, M.3
  • 107
    • 85010641654 scopus 로고    scopus 로고
    • Marine omega-3 Polyunsaturated Fatty Acid Intake and Risk of Colorectal Cancer Characterized by Tumor-Infiltrating T Cells
    • Song M, Nishihara R, Cao Y, et al. Marine omega-3 Polyunsaturated Fatty Acid Intake and Risk of Colorectal Cancer Characterized by Tumor-Infiltrating T Cells. JAMA Oncol. 2016.
    • (2016) JAMA Oncol
    • Song, M.1    Nishihara, R.2    Cao, Y.3
  • 108
    • 84976555081 scopus 로고    scopus 로고
    • Body mass index and risk of colorectal cancer according to tumor lymphocytic infiltrate
    • COI: 1:CAS:528:DC%2BC28XnsV2lsrc%3D, PID: 27037951
    • Hanyuda A, Ogino S, Qian ZR, et al. Body mass index and risk of colorectal cancer according to tumor lymphocytic infiltrate. Int J Cancer. 2016;139:854–68.
    • (2016) Int J Cancer , vol.139 , pp. 854-868
    • Hanyuda, A.1    Ogino, S.2    Qian, Z.R.3
  • 109
    • 84964398060 scopus 로고    scopus 로고
    • Microsatellite instability as a biomarker for PD-1 blockade
    • COI: 1:CAS:528:DC%2BC28XivFGmsbY%3D, PID: 26880610
    • Dudley JC, Lin MT, Le DT, et al. Microsatellite instability as a biomarker for PD-1 blockade. Clin Cancer Res. 2016;22:813–20.
    • (2016) Clin Cancer Res , vol.22 , pp. 813-820
    • Dudley, J.C.1    Lin, M.T.2    Le, D.T.3
  • 110
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • COI: 1:CAS:528:DC%2BC38Xhtleru7jO, PID: 22972295
    • Lozupone CA, Stombaugh JI, Gordon JI, et al. Diversity, stability and resilience of the human gut microbiota. Nature. 2012;489:220–30.
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3
  • 111
    • 84886743078 scopus 로고    scopus 로고
    • Potential role of gastrointestinal microbiota composition in prostate cancer risk
    • PID: 24180596
    • Amirian ES, Petrosino JF, Ajami NJ, et al. Potential role of gastrointestinal microbiota composition in prostate cancer risk. Infect Agent Cancer. 2013;8:42.
    • (2013) Infect Agent Cancer. , vol.8 , pp. 42
    • Amirian, E.S.1    Petrosino, J.F.2    Ajami, N.J.3
  • 112
    • 84979997683 scopus 로고    scopus 로고
    • Current knowledge and future research directions on fecal bacterial patterns and their association with asthma
    • PID: 27445990
    • Claassen-Weitz S, Wiysonge CS, Machingaidze S, et al. Current knowledge and future research directions on fecal bacterial patterns and their association with asthma. Front Microbiol. 2016;7:838.
    • (2016) Front Microbiol. , vol.7 , pp. 838
    • Claassen-Weitz, S.1    Wiysonge, C.S.2    Machingaidze, S.3
  • 113
    • 84891473723 scopus 로고    scopus 로고
    • Human gut microbiome and risk for colorectal cancer
    • COI: 1:CAS:528:DC%2BC2cXhs1yrsQ%3D%3D, PID: 24316595
    • Ahn J, Sinha R, Pei Z, et al. Human gut microbiome and risk for colorectal cancer. J Natl Cancer Inst. 2013;105:1907–11.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1907-1911
    • Ahn, J.1    Sinha, R.2    Pei, Z.3
  • 114
    • 85016726917 scopus 로고    scopus 로고
    • Tumour-associated and non-tumour-associated microbiota in colorectal cancer
    • Flemer B, Lynch DB, Brown JM, et al. Tumour-associated and non-tumour-associated microbiota in colorectal cancer. Gut. 2016.
    • (2016) Gut
    • Flemer, B.1    Lynch, D.B.2    Brown, J.M.3
  • 115
    • 84863022950 scopus 로고    scopus 로고
    • Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
    • COI: 1:CAS:528:DC%2BC38XhsFygtrg%3D, PID: 22009990
    • Kostic AD, Gevers D, Pedamallu CS, et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res. 2012;22:292–8.
    • (2012) Genome Res , vol.22 , pp. 292-298
    • Kostic, A.D.1    Gevers, D.2    Pedamallu, C.S.3
  • 116
    • 84856534859 scopus 로고    scopus 로고
    • Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
    • COI: 1:CAS:528:DC%2BC38XhsFygtrk%3D, PID: 22009989
    • Castellarin M, Warren RL, Freeman JD, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res. 2012;22:299–306.
    • (2012) Genome Res , vol.22 , pp. 299-306
    • Castellarin, M.1    Warren, R.L.2    Freeman, J.D.3
  • 117
    • 85001843058 scopus 로고    scopus 로고
    • Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis
    • Mima K, Nishihara R, Qian ZR, et al. Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis. Gut. 2015.
    • (2015) Gut
    • Mima, K.1    Nishihara, R.2    Qian, Z.R.3
  • 118
    • 85010756263 scopus 로고    scopus 로고
    • Fusobacterium nucleatum and T Cells in colorectal carcinoma
    • PID: 26181352
    • Mima K, Sukawa Y, Nishihara R, et al. Fusobacterium nucleatum and T Cells in colorectal carcinoma. JAMA Oncol. 2015;1:653–61.
    • (2015) JAMA Oncol. , vol.1 , pp. 653-661
    • Mima, K.1    Sukawa, Y.2    Nishihara, R.3
  • 119
    • 84896527392 scopus 로고    scopus 로고
    • Fusobacterium in colonic flora and molecular features of colorectal carcinoma
    • COI: 1:CAS:528:DC%2BC2cXktF2rs7w%3D, PID: 24385213
    • Tahara T, Yamamoto E, Suzuki H, et al. Fusobacterium in colonic flora and molecular features of colorectal carcinoma. Cancer Res. 2014;74:1311–8.
    • (2014) Cancer Res , vol.74 , pp. 1311-1318
    • Tahara, T.1    Yamamoto, E.2    Suzuki, H.3
  • 120
    • 84936847682 scopus 로고    scopus 로고
    • Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway
    • COI: 1:CAS:528:DC%2BC2MXkt1yis7w%3D, PID: 25703934
    • Ito M, Kanno S, Nosho K, et al. Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway. Int J Cancer. 2015;137:1258–68.
    • (2015) Int J Cancer , vol.137 , pp. 1258-1268
    • Ito, M.1    Kanno, S.2    Nosho, K.3
  • 121
    • 84948461699 scopus 로고    scopus 로고
    • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
    • COI: 1:CAS:528:DC%2BC2MXhvFamtL3J, PID: 26541610
    • Vetizou M, Pitt JM, Daillere R, et al. Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota. Science. 2015;350:1079–84.
    • (2015) Science , vol.350 , pp. 1079-1084
    • Vetizou, M.1    Pitt, J.M.2    Daillere, R.3
  • 122
    • 84948451779 scopus 로고    scopus 로고
    • Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
    • COI: 1:CAS:528:DC%2BC2MXhvFamtL3K, PID: 26541606
    • Sivan A, Corrales L, Hubert N, et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science. 2015;350:1084–9.
    • (2015) Science , vol.350 , pp. 1084-1089
    • Sivan, A.1    Corrales, L.2    Hubert, N.3
  • 123
    • 84989225686 scopus 로고    scopus 로고
    • Genomic characterization of response to chemoradiation in urothelial bladder cancer, Cancer
    • Desai NB, Scott SN, Zabor EC, et al. Genomic characterization of response to chemoradiation in urothelial bladder cancer. Cancer. 2016.
    • (2016) et al
    • Desai, N.B.1    Scott, S.N.2    Zabor, E.C.3
  • 124
    • 85002548288 scopus 로고    scopus 로고
    • Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study
    • Dixon SC, Nagle CM, Thrift AP, et al. Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. Int J Epidemiol. 2016.
    • (2016) Int J Epidemiol
    • Dixon, S.C.1    Nagle, C.M.2    Thrift, A.P.3
  • 125
    • 84979992948 scopus 로고    scopus 로고
    • MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival
    • COI: 1:CAS:528:DC%2BC28Xht1yhtbvE, PID: 26957558
    • Mima K, Nishihara R, Yang J, et al. MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival. Clin Cancer Res. 2016;22:3841–8.
    • (2016) Clin Cancer Res , vol.22 , pp. 3841-3848
    • Mima, K.1    Nishihara, R.2    Yang, J.3
  • 126
    • 84959924132 scopus 로고    scopus 로고
    • Reproductive risk factors in relation to molecular subtypes of breast cancer: results from the nurses’ health studies
    • COI: 1:CAS:528:DC%2BC28XitFCms7g%3D, PID: 26684063
    • Sisti JS, Collins LC, Beck AH, et al. Reproductive risk factors in relation to molecular subtypes of breast cancer: results from the nurses’ health studies. Int J Cancer. 2016;138:2346–56.
    • (2016) Int J Cancer , vol.138 , pp. 2346-2356
    • Sisti, J.S.1    Collins, L.C.2    Beck, A.H.3
  • 127
    • 84983479239 scopus 로고    scopus 로고
    • Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival
    • Mima K, Nowak JA, Qian ZR, et al. Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival. Oncotarget. 2016.
    • (2016) Oncotarget
    • Mima, K.1    Nowak, J.A.2    Qian, Z.R.3
  • 128
    • 84959132509 scopus 로고    scopus 로고
    • Healthy dietary patterns and risk of breast cancer by molecular subtype
    • COI: 1:CAS:528:DC%2BC28XivFOksrc%3D, PID: 26872903
    • Hirko KA, Willett WC, Hankinson SE, et al. Healthy dietary patterns and risk of breast cancer by molecular subtype. Breast Cancer Res Treat. 2016;155:579–88.
    • (2016) Breast Cancer Res Treat , vol.155 , pp. 579-588
    • Hirko, K.A.1    Willett, W.C.2    Hankinson, S.E.3
  • 129
    • 84940663769 scopus 로고    scopus 로고
    • Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk
    • COI: 1:CAS:528:DC%2BC28Xht1CisL3M, PID: 26025909
    • Simons CC, Schouten LJ, Godschalk R, et al. Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk. Carcinogenesis. 2015;36:971–81.
    • (2015) Carcinogenesis , vol.36 , pp. 971-981
    • Simons, C.C.1    Schouten, L.J.2    Godschalk, R.3
  • 130
    • 84941779721 scopus 로고    scopus 로고
    • Association between body mass index and mortality for colorectal cancer survivors: overall and by tumor molecular phenotype
    • COI: 1:CAS:528:DC%2BC2MXht1yqsrfE, PID: 26038390
    • Campbell PT, Newton CC, Newcomb PA, et al. Association between body mass index and mortality for colorectal cancer survivors: overall and by tumor molecular phenotype. Cancer Epidemiol Biomarkers Prev. 2015;24:1229–38.
    • (2015) Cancer Epidemiol Biomarkers Prev. , vol.24 , pp. 1229-1238
    • Campbell, P.T.1    Newton, C.C.2    Newcomb, P.A.3
  • 131
    • 84941789405 scopus 로고    scopus 로고
    • Prediagnostic physical activity and colorectal cancer survival: overall and stratified by tumor characteristics
    • PID: 25976417
    • Hardikar S, Newcomb PA, Campbell PT, et al. Prediagnostic physical activity and colorectal cancer survival: overall and stratified by tumor characteristics. Cancer Epidemiol Biomarkers Prev. 2015;24:1130–7.
    • (2015) Cancer Epidemiol Biomarkers Prev. , vol.24 , pp. 1130-1137
    • Hardikar, S.1    Newcomb, P.A.2    Campbell, P.T.3
  • 132
    • 84907163101 scopus 로고    scopus 로고
    • Body size, physical activity, early-life energy restriction, and associations with methylated insulin-like growth factor-binding protein genes in colorectal cancer
    • COI: 1:CAS:528:DC%2BC2cXhsVyrsr%2FM, PID: 24972776
    • Simons CC, van den Brandt PA, Stehouwer CD, et al. Body size, physical activity, early-life energy restriction, and associations with methylated insulin-like growth factor-binding protein genes in colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2014;23:1852–62.
    • (2014) Cancer Epidemiol Biomarkers Prev. , vol.23 , pp. 1852-1862
    • Simons, C.C.1    van den Brandt, P.A.2    Stehouwer, C.D.3
  • 133
    • 84895788624 scopus 로고    scopus 로고
    • Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype
    • COI: 1:CAS:528:DC%2BC2cXhtVymu7o%3D, PID: 24448365
    • Zhu Y, Yang SR, Wang PP, et al. Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype. Br J Cancer. 2014;110:1359–66.
    • (2014) Br J Cancer , vol.110 , pp. 1359-1366
    • Zhu, Y.1    Yang, S.R.2    Wang, P.P.3
  • 134
    • 84901917862 scopus 로고    scopus 로고
    • Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability
    • PID: 24885829
    • Brandstedt J, Wangefjord S, Nodin B, et al. Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability. BMC Cancer. 2014;14:371.
    • (2014) BMC Cancer , vol.14 , pp. 371
    • Brandstedt, J.1    Wangefjord, S.2    Nodin, B.3
  • 135
    • 84884189727 scopus 로고    scopus 로고
    • Long-term colorectal-cancer incidence and mortality after lower endoscopy
    • COI: 1:CAS:528:DC%2BC3sXhsFajtbjE, PID: 24047059
    • Nishihara R, Wu K, Lochhead P, et al. Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med. 2013;369:1095–105.
    • (2013) N Engl J Med , vol.369 , pp. 1095-1105
    • Nishihara, R.1    Wu, K.2    Lochhead, P.3
  • 136
    • 84883142215 scopus 로고    scopus 로고
    • Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location
    • COI: 1:CAS:528:DC%2BC3sXhtlSis7rK, PID: 23900220
    • Bae JM, Kim JH, Cho NY, et al. Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location. Br J Cancer. 2013;109:1004–12.
    • (2013) Br J Cancer , vol.109 , pp. 1004-1012
    • Bae, J.M.1    Kim, J.H.2    Cho, N.Y.3
  • 137
    • 84864607258 scopus 로고    scopus 로고
    • Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis
    • PID: 22531127
    • Hughes LA, Williamson EJ, van Engeland M, et al. Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis. Int J Epidemiol. 2012;41:1060–72.
    • (2012) Int J Epidemiol , vol.41 , pp. 1060-1072
    • Hughes, L.A.1    Williamson, E.J.2    van Engeland, M.3
  • 138
    • 84994850679 scopus 로고    scopus 로고
    • Regular Aspirin Use Associates with Lower Risk of Colorectal Cancers With Low Numbers of Tumor-infiltrating Lymphocytes
    • Cao Y, Nishihara R, Qian ZR, et al. Regular Aspirin Use Associates with Lower Risk of Colorectal Cancers With Low Numbers of Tumor-infiltrating Lymphocytes. Gastroenterology. 2016.
    • (2016) Gastroenterology
    • Cao, Y.1    Nishihara, R.2    Qian, Z.R.3
  • 139
    • 84965058071 scopus 로고    scopus 로고
    • Antibiotic use and its consequences for the normal microbiome
    • COI: 1:CAS:528:DC%2BC28Xms1KisL4%3D, PID: 27126037
    • Blaser MJ. Antibiotic use and its consequences for the normal microbiome. Science. 2016;352:544–5.
    • (2016) Science , vol.352 , pp. 544-545
    • Blaser, M.J.1
  • 140
    • 84960532900 scopus 로고    scopus 로고
    • The influence of non-steroidal anti-inflammatory drugs on the gut microbiome
    • Rogers MA, Aronoff DM. The influence of non-steroidal anti-inflammatory drugs on the gut microbiome. Clin Microbiol Infect. 2016;22(178):e1–9.
    • (2016) Clin Microbiol Infect , vol.22 , Issue.178 , pp. e1-e9
    • Rogers, M.A.1    Aronoff, D.M.2
  • 141
    • 84880532290 scopus 로고    scopus 로고
    • Breast cancer risk prediction with heterogeneous risk profiles according to breast cancer tumor markers
    • PID: 23645624
    • Rosner B, Glynn RJ, Tamimi RM, et al. Breast cancer risk prediction with heterogeneous risk profiles according to breast cancer tumor markers. Am J Epidemiol. 2013;178:296–308.
    • (2013) Am J Epidemiol , vol.178 , pp. 296-308
    • Rosner, B.1    Glynn, R.J.2    Tamimi, R.M.3
  • 142
    • 85006190060 scopus 로고    scopus 로고
    • Identifying etiologically distinct sub-types of cancer: a demonstration project involving breast cancer
    • COI: 1:CAS:528:DC%2BC2MXhsVyqu7zN, PID: 25974664
    • Begg CB, Orlow I, Zabor EC, et al. Identifying etiologically distinct sub-types of cancer: a demonstration project involving breast cancer. Cancer Med. 2015;4:1432–9.
    • (2015) Cancer Med. , vol.4 , pp. 1432-1439
    • Begg, C.B.1    Orlow, I.2    Zabor, E.C.3
  • 143
    • 84938801963 scopus 로고    scopus 로고
    • A meta-regression method for studying etiological heterogeneity across disease subtypes classified by multiple biomarkers
    • PID: 26116215
    • Wang M, Kuchiba A, Ogino S. A meta-regression method for studying etiological heterogeneity across disease subtypes classified by multiple biomarkers. Am J Epidemiol. 2015;182:263–70.
    • (2015) Am J Epidemiol , vol.182 , pp. 263-270
    • Wang, M.1    Kuchiba, A.2    Ogino, S.3
  • 144
    • 84956582609 scopus 로고    scopus 로고
    • Statistical methods for studying disease subtype heterogeneity
    • PID: 26619806
    • Wang M, Spiegelman D, Kuchiba A, et al. Statistical methods for studying disease subtype heterogeneity. Stat Med. 2016;35:782–800.
    • (2016) Stat Med , vol.35 , pp. 782-800
    • Wang, M.1    Spiegelman, D.2    Kuchiba, A.3
  • 145
    • 84964342326 scopus 로고    scopus 로고
    • Using the Lorenz curve to characterize risk predictiveness and etiologic heterogeneity
    • PID: 27096256
    • Mauguen A, Begg CB. Using the Lorenz curve to characterize risk predictiveness and etiologic heterogeneity. Epidemiology. 2016;27:531–7.
    • (2016) Epidemiology. , vol.27 , pp. 531-537
    • Mauguen, A.1    Begg, C.B.2
  • 146
    • 84923912562 scopus 로고    scopus 로고
    • Genomic investigation of etiologic heterogeneity: methodologic challenges
    • PID: 25532962
    • Begg CB, Seshan VE, Zabor EC, et al. Genomic investigation of etiologic heterogeneity: methodologic challenges. BMC Med Res Methodol. 2014;14:138.
    • (2014) BMC Med Res Methodol , vol.14 , pp. 138
    • Begg, C.B.1    Seshan, V.E.2    Zabor, E.C.3
  • 147
    • 77955885005 scopus 로고    scopus 로고
    • Analysis of cohort studies with multivariate and partially observed disease classification data
    • PID: 22822252
    • Chatterjee N, Sinha S, Diver WR, et al. Analysis of cohort studies with multivariate and partially observed disease classification data. Biometrika. 2010;97:683–98.
    • (2010) Biometrika , vol.97 , pp. 683-698
    • Chatterjee, N.1    Sinha, S.2    Diver, W.R.3
  • 148
    • 84864613664 scopus 로고    scopus 로고
    • Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science
    • PID: 22935517
    • Ogino S, King EE, Beck AH, et al. Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science. Am J Epidemiol. 2012;176:659–67.
    • (2012) Am J Epidemiol , vol.176 , pp. 659-667
    • Ogino, S.1    King, E.E.2    Beck, A.H.3
  • 149
    • 84867734462 scopus 로고    scopus 로고
    • Invited commentary: the 21st century epidemiologist—a need for different training?
    • PID: 22935514
    • Kuller LH. Invited commentary: the 21st century epidemiologist—a need for different training? Am J Epidemiol. 2012;176:668–71.
    • (2012) Am J Epidemiol , vol.176 , pp. 668-671
    • Kuller, L.H.1
  • 150
    • 84867725133 scopus 로고    scopus 로고
    • Ogino et Al. Respond to “the 21st century epidemiologist
    • PID: 22935516
    • Ogino S, Beck AH, King EE, et al. Ogino et Al. Respond to “the 21st century epidemiologist”. Am J Epidemiol. 2012;176:672–4.
    • (2012) Am J Epidemiol , vol.176 , pp. 672-674
    • Ogino, S.1    Beck, A.H.2    King, E.E.3
  • 151
    • 84976511116 scopus 로고    scopus 로고
    • All biomedical and health science researchers, including laboratory physicians and scientists, need adequate education and training in study design and statistics
    • COI: 1:CAS:528:DC%2BC28Xhs1egs7%2FO, PID: 27354573
    • Ogino S, Nishihara R. All biomedical and health science researchers, including laboratory physicians and scientists, need adequate education and training in study design and statistics. Clin Chem. 2016;62:1039–40.
    • (2016) Clin Chem , vol.62 , pp. 1039-1040
    • Ogino, S.1    Nishihara, R.2


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