Body size, physical activity, early-life energy restriction, and associations with methylated insulin-like growth factor-binding protein genes in colorectal cancer

Cancer Epidemiology Biomarkers and Prevention

Volumn 23, Issue 9, 2014, Pages 1852-1862

  Simons, Colinda C J M ^a   Van Den Brandt, Piet A ^a   Stehouwer, Coen D A ^b   Van Engeland, Manon ^a   Weijenberg, Matty P ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 7; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BODY MASS; BODY SIZE; CALORIC RESTRICTION; CANCER RISK; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; FEMALE; FOOD FREQUENCY QUESTIONNAIRE; GENE; GENETIC ASSOCIATION; GENETIC RISK; HAZARD RATIO; HUMAN; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN GENE; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; PHYSICAL ACTIVITY; POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SELF REPORT; SEX DIFFERENCE; WINTER; COLORECTAL NEOPLASMS; GENETICS; MIDDLE AGED; MOTOR ACTIVITY; PROMOTER REGION;

AGED; BODY SIZE; COHORT STUDIES; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; MIDDLE AGED; MOTOR ACTIVITY; NETHERLANDS; PROMOTER REGIONS, GENETIC;

EID: 84907163101     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-13-1285     Document Type: Article

References (54)

1. Kaaks R, Lukanova A. Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proc Nutr Soc 2001; 60: 91-106.
2. Sandhu MS, Dunger DB, Giovannucci EL. Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst 2002; 94: 972-80.
3. Durai R, Yang W, Gupta S, Seifalian AM, Winslet MC. The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge. Int J Colorectal Dis 2005; 20: 203-20.
4. Yamada PM, Lee K-W. Perspectives in mammalian IGFBP-3 biology: local vs. systemic action. Am J Physiol Cell Physiol 2009; 296: C954-976.
5. Baxter RC. IGF binding proteins in cancer: mechanistic and clinical insights. Nat Rev Cancer 2014; 14: 329-41.
6. Ibanez de Caceres I, Dulaimi E, Hoffman AM, Al-Saleem T, Uzzo RG, Cairns P. Identification of novel target genes by an epigenetic reactivation screen of renal cancer. Cancer Res 2006; 66: 5021-8.
7. Sato H, Yazawa T, Suzuki T, Shimoyamada H, Okudela K, Ikeda M, et al. Growth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia. Am J Pathol 2006; 169: 1550-66.
8. Lin J, Lai M, Huang Q, Ma Y, Cui J, Ruan W. Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. J Pathol 2007; 212: 83-90.
9. Ye F, Chen Y, Knösel T, Schlüns K, Pacyna-Gengelbach M, Deutschmann N, et al. Decreased expression of insulin-like growth factor binding protein 7 in human colorectal carcinoma is related to DNA methylation. J Cancer Res Clin Oncol 2007; 133: 305-14.
10. Vizioli MG, Sensi M, Miranda C, Cleris L, Formelli F, Anania MC, et al. IGFBP7: an oncosuppressor gene in thyroid carcinogenesis. Oncogene 2010; 29: 3835-44.
11. Chen Y, Cui T, Knösel T, Yang L, Zöller K, Petersen I. IGFBP7 is a p53 target gene inactivated in human lung cancer by DNA hypermethylation. Lung Cancer 2011; 73: 38-44.
12. Gu T, Gu HF, Hilding A, Sjöholm LK, Ostenson C-G, Ekström TJ, et al. Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men. Clin Epigenetics 2013; 5: 21.
13. Deng L, Gui Z, Zhao L, Wang J, Shen L. Diabetes mellitus and the incidence of colorectal cancer: an updated systematic review and meta-analysis. Dig Dis Sci 2012; 57: 1576-85.
14. Van Vlodrop IJH, Niessen HEC, Derks S, Baldewijns MMLL, van Criekinge W, Herman JG, et al. Analysis of promoter CpG island hypermethylation in cancer: location, location, location! Clin Cancer Res 2011; 17: 4225-31.
15. Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology 2010; 138: 2073-2087.
16. Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci U S A 1999; 96: 8681-6.
17. Van den Brandt PA, Goldbohm RA, van 't Veer P, Volovics A, Hermus RJ, Sturmans F. A large-scale prospective cohort study on diet and cancer in The Netherlands. J Clin Epidemiol 1990; 43: 285-95.
18. Goldbohm RA, van den Brandt PA, Brants HA, van't Veer P, Al M, Sturmans F, et al. Validation of a dietary questionnaire used in a largescale prospective cohort study on diet and cancer. Eur J Clin Nutr 1994; 48: 253-65.
19. Goldbohm RA, van 't Veer P, van den Brandt PA, van 't Hof MA, Brants HA, Sturmans F, et al. Reproducibility of a food frequency questionnaire and stability of dietary habits determined from five annually repeated measurements. Eur J Clin Nutr 1995; 49: 420-9.
20. Nevo Table. Dutch foodcomposition table 1986-7. The Hague, Netherlands: Voorlichtingsbureau voor de Voeding; 1986.
21. Casparie M, Tiebosch ATMG, Burger G, Blauwgeers H, van de Pol A, van Krieken JHJM, et al. Pathology databanking and biobanking in The Netherlands, a central role for PALGA, the nationwide histopathology and cytopathology data network and archive. Cell Oncol 2007; 29: 19-24.
22. Goldbohm RA, van den Brandt PA, Dorant E. Estimation of the coverage of Dutch municipalities by cancer registries and PALGA based on hospital discharge data. Tijdschr Soc Gezondheidsz 1994; 72: 80-84.
23. Van den Brandt PA, Schouten LJ, Goldbohm RA, Dorant E, Hunen PM. Development of a record linkage protocol for use in the Dutch Cancer Registry for Epidemiological Research. Int J Epidemiol 1990; 19: 553-8.
24. WHO: Global Database on Body Mass Index. Available from: http://apps.who.int/bmi/index.jsp?introPage=intro-3.html. Accessed: April 1, 2013.
25. Hughes LA, Schouten LJ, Goldbohm RA, van den Brandt PA, Weijenberg MP. Self-reported clothing size as a proxy measure for body size. Epidemiology 2009; 20: 673-6.
26. Hettinger TH. Ermittlung des Arbeitsenergieumsatzes bei Dynamisch Muskulaerer Arbeit. Dortmund, Germany: Bundesarbeit fuer Abeitsschutz; 1989.
27. Simons CCJM, Hughes LAE, van Engeland M, Goldbohm RA, van den Brandt PA, Weijenberg MP. Physical activity, occupational sitting time, and colorectal cancer risk in the Netherlands cohort study. Am J Epidemiol 2013; 177: 514-30.
28. Burger G, Sandstead H, Drummond J. Malnutrition and Starvation in Western Netherlands, September 1944 to July 1945. Part I and II. The Hague, the Netherlands: General State Printing Office; 1948.
29. Trienekens G. Tussen ons volk en de honger. De voedselvoorziening, 1940-45. (English translation: Between our nation and the hunger. The food supply, 1940-45). Utrecht, the Netherlands: Stichting Matrijs; 1985.
30. Herman JG, Graff JR, Myöhänen S, Nelkin BD, Baylin SB. MethylationspecificPCR: a novelPCRassay for methylation status ofCpGislands. Proc Natl Acad Sci U S A 1996; 93: 9821-6.
31. Derks S, LentjesMHFM, Hellebrekers DMEI, de Bruïne AP, Herman JG, van Engeland M. Methylation-specific PCR unraveled. Cell Oncol 2004; 26: 291-9.
32. Weisenberger DJ, Siegmund KD, CampanM, Young J, Long TI, Faasse MA, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006; 38: 787-93.
33. Hughes LAE, van den Brandt PA, de Bruïne AP, Wouters KAD, Hulsmans S, Spiertz A, et al. Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms. PLoS ONE 2009; 4: e7951.
34. Suraweera N, Duval A, Reperant M, Vaury C, Furlan D, Leroy K, et al. Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology 2002; 123: 1804-11.
35. Hughes LAE, Simons CCJM, van den Brandt PA, Goldbohm RA, van Engeland M, WeijenbergMP. Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study. Am J Epidemiol 2011; 174: 1127-39.
36. Hughes LAE, van den Brandt PA, Goldbohm RA, de Goeij AFPM, de Bruïne AP, van Engeland M, et al. Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study. Int J Epidemiol 2010; 39: 1333-44.
37. Ogino S, Chan AT, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut 2010; 60: 397-411.
38. Ali O, Cohen P, Lee KW. Epidemiology and biology of insulin-like growth factor binding protein-3 (IGFBP-3) as an anti-cancer molecule. Horm Metab Res 2003; 35: 726-33.
39. Renehan AG, Zwahlen M, Minder C, O'Dwyer ST, Shalet SM, Egger M. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 2004; 363: 1346-53.
40. Derks S, Postma C, Moerkerk PTM, van den Bosch SM, Carvalho B, Hermsen MAJA, et al. Promoter methylation precedes chromosomal alterations in colorectal cancer development. Cell Oncol 2006; 28: 247-57.
41. Hughes LAE, Khalid-de Bakker CAJ, Smits KM, van den Brandt PA, Jonkers D, Ahuja N, et al. The CpG island methylator phenotype in colorectal cancer: progress and problems. Biochim Biophys Acta 2012; 1825: 77-85.
42. Hughes LAE, Williamson EJ, van Engeland M, Jenkins MA, Giles GG, Hopper JL, et al. Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis. Int J Epidemiol 2012; 41: 1060-72.
43. Hughes LAE, Simons CCJM, van den Brandt PA, Goldbohm RA, de Goeij AF, de Bruïne AP, et al. Body size, physical activity and risk of colorectal cancer with or without theCpG island methylator phenotype (CIMP). PLoS ONE 2011; 6: e18571.
44. Dossus L, Kaaks R. Nutrition, metabolic factors and cancer risk. Best Pract Res Clin Endocrinol Metab 2008; 22: 551-71.
45. Monteiro R, Azevedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm 2010; 2010. Article ID 289645, 10 pages.
46. Suzuki H, Toyota M, Sato H, Sonoda T, Sakauchi F, Mori M. Roles and causes of abnormal DNA methylation in gastrointestinal cancers. Asian Pac J Cancer Prev 2006; 7: 177-85.
47. Slattery ML, Curtin K, Anderson K, Ma KN, Ballard L, Edwards S, et al. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J Natl Cancer Inst 2000; 92: 1831-6.
48. Campbell PT, Jacobs ET, Ulrich CM, Figueiredo JC, Poynter JN, McLaughlin JR, et al. Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. J Natl Cancer Inst 2010; 102: 391-400.
49. Slattery ML, Curtin K, Sweeney C, Levin TR, Potter J, Wolff RK, et al. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 2007; 120: 656-63.
50. Slattery ML, Curtin K, Wolff RK, Herrick JS, Caan BJ, Samowitz W. Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes. Cancer Causes Control 2010; 21: 1237-45.
51. Simons CCJM, Hughes LAE, Smits KM, Khalid-de Bakker CA, de Bruïne AP, Carvalho B, et al. A novel classification of colorectal tumors based on microsatellite instability, the CpG island methylator phenotype and chromosomal instability: implications for prognosis. Ann Oncol 2013; 24: 2048-56.
52. Rashid A, Shen L, Morris JS, Issa JP, Hamilton SR. CpG island methylation in colorectal adenomas. Am J Pathol 2001; 159: 1129-35.
53. Jass JR. Molecular heterogeneity of colorectal cancer: Implications for cancer control. Surg Oncol 2007; 16 Suppl 1: S7-9.
54. Spencer EA, Appleby PN, Davey GK, Key TJ. Validity of self-reported height and weight in 4808 EPIC-Oxford participants. Public Health Nutr 2002; 5: 561-5.