메뉴 건너뛰기




Volumn 1, Issue , 2013, Pages

Immune evasion in acute myeloid leukemia: Current concepts and future directions

Author keywords

Acute myeloid leukemia; Anti tumor immunity; Immune evasion

Indexed keywords

4 AMINO N (3 CHLORO 4 FLUOROPHENYL) N' HYDROXY 1,2,5 OXADIAZOLE 3 CARBOXIMIDAMIDE; ANTINEOPLASTIC AGENT; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DACLIZUMAB; DENDRITIC CELL VACCINE; GAMMA INTERFERON; IMP321; INDOLEAMINE 2,3 DIOXYGENASE; IPILIMUMAB; PROGRAMMED DEATH 1 RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84991030654     PISSN: None     EISSN: 20511426     Source Type: Journal    
DOI: 10.1186/2051-1426-1-13     Document Type: Review
Times cited : (104)

References (114)
  • 1
    • 79952129510 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns
    • Gupta V, Tallman MS, Weisdorf DJ: Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns. Blood 2011, 117:2307-2318.
    • (2011) Blood , vol.117 , pp. 2307-2318
    • Gupta, V.1    Tallman, M.S.2    Weisdorf, D.J.3
  • 7
    • 58149359323 scopus 로고    scopus 로고
    • Leukemia-associated antigens are critical for the proliferation of acute myeloid leukemia cells
    • Greiner J, Bullinger L, Guinn BA, Dohner H, Schmitt M: Leukemia-associated antigens are critical for the proliferation of acute myeloid leukemia cells. Clin Cancer Res 2008, 14:7161-7166.
    • (2008) Clin Cancer Res , vol.14 , pp. 7161-7166
    • Greiner, J.1    Bullinger, L.2    Guinn, B.A.3    Dohner, H.4    Schmitt, M.5
  • 9
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ: Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004, 4:891-899.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 10
    • 0027406425 scopus 로고
    • T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors
    • Alexander JP, Kudoh S, Melsop KA, Hamilton TA, Edinger MG, Tubbs RR, Sica D, Tuason L, Klein E, Bukowski RM, et al: T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. Cancer Res 1993, 53:1380-1387.
    • (1993) Cancer Res , vol.53 , pp. 1380-1387
    • Alexander, J.P.1    Kudoh, S.2    Melsop, K.A.3    Hamilton, T.A.4    Edinger, M.G.5    Tubbs, R.R.6    Sica, D.7    Tuason, L.8    Klein, E.9    Bukowski, R.M.10
  • 12
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, Anderson AC: Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 2010, 207:2187-2194.
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5    Anderson, A.C.6
  • 15
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S: Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009, 9:162-174.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 16
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W: Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006, 6:295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 17
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of "tumor escape" phenotypes
    • Khong HT, Restifo NP: Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat Immunol 2002, 3:999-1005.
    • (2002) Nat Immunol , vol.3 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 22
    • 84874982295 scopus 로고    scopus 로고
    • Myeloid leukemia cells with a B7-2(+) subpopulation provoke Th-cell responses and become immunosuppressive through the modulation of B7 ligands
    • Dolen Y, Esendagli G: Myeloid leukemia cells with a B7-2(+) subpopulation provoke Th-cell responses and become immunosuppressive through the modulation of B7 ligands. Eur J Immunol 2013, 43:747-757.
    • (2013) Eur J Immunol , vol.43 , pp. 747-757
    • Dolen, Y.1    Esendagli, G.2
  • 24
    • 0031405867 scopus 로고    scopus 로고
    • Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells
    • Chambers CA, Sullivan TJ, Allison JP: Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells. Immunity 1997, 7:885-895.
    • (1997) Immunity , vol.7 , pp. 885-895
    • Chambers, C.A.1    Sullivan, T.J.2    Allison, J.P.3
  • 26
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach DR, Krummel MF, Allison JP: Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996, 271:1734-1736.
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 27
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
    • Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP: Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J Exp Med 2009, 206:1717-1725.
    • (2009) J Exp Med , vol.206 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 30
    • 34250223096 scopus 로고    scopus 로고
    • A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormonerefractory prostate cancer
    • Small EJ, Tchekmedyian NS, Rini BI, Fong L, Lowy I, Allison JP: A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormonerefractory prostate cancer. Clin Cancer Res 2007, 13:1810-1815.
    • (2007) Clin Cancer Res , vol.13 , pp. 1810-1815
    • Small, E.J.1    Tchekmedyian, N.S.2    Rini, B.I.3    Fong, L.4    Lowy, I.5    Allison, J.P.6
  • 31
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV nonsmall-cell lung cancer: results from a randomized, double-blind, multicenter phase II study
    • Lynch TJ, Bondarenko I, Luft A, Serwatowski P, Barlesi F, Chacko R, Sebastian M, Neal J, Lu H, Cuillerot JM, Reck M: Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV nonsmall-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol 2012, 30:2046-2054.
    • (2012) J Clin Oncol , vol.30 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3    Serwatowski, P.4    Barlesi, F.5    Chacko, R.6    Sebastian, M.7    Neal, J.8    Lu, H.9    Cuillerot, J.M.10    Reck, M.11
  • 32
    • 0037085792 scopus 로고    scopus 로고
    • Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia
    • LaBelle JL, Hanke CA, Blazar BR, Truitt RL: Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia. Blood 2002, 99:2146-2153.
    • (2002) Blood , vol.99 , pp. 2146-2153
    • LaBelle, J.L.1    Hanke, C.A.2    Blazar, B.R.3    Truitt, R.L.4
  • 33
    • 33344466283 scopus 로고    scopus 로고
    • CTLA-4 blockade by a human MAb enhances the capacity of AML-derived DC to induce T-cell responses against AML cells in an autologous culture system
    • Zhong RK, Loken M, Lane TA, Ball ED: CTLA-4 blockade by a human MAb enhances the capacity of AML-derived DC to induce T-cell responses against AML cells in an autologous culture system. Cytotherapy 2006, 8:3-12.
    • (2006) Cytotherapy , vol.8 , pp. 3-12
    • Zhong, R.K.1    Loken, M.2    Lane, T.A.3    Ball, E.D.4
  • 38
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupuslike autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T: Development of lupuslike autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999, 11:141-151.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 40
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
    • Zhang L, Gajewski TF, Kline J: PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. Blood 2009, 114:1545-1552.
    • (2009) Blood , vol.114 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 43
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM: The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012, 12:252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 44
    • 0027979962 scopus 로고
    • Cellular expression and tissue distribution of the human LAG-3-encoded protein, an MHC class II ligand
    • Huard B, Gaulard P, Faure F, Hercend T, Triebel F: Cellular expression and tissue distribution of the human LAG-3-encoded protein, an MHC class II ligand. Immunogenetics 1994, 39:213-217.
    • (1994) Immunogenetics , vol.39 , pp. 213-217
    • Huard, B.1    Gaulard, P.2    Faure, F.3    Hercend, T.4    Triebel, F.5
  • 46
    • 0038068048 scopus 로고    scopus 로고
    • The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells
    • Workman CJ, Vignali DA: The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells. Eur J Immunol 2003, 33:970-979.
    • (2003) Eur J Immunol , vol.33 , pp. 970-979
    • Workman, C.J.1    Vignali, D.A.2
  • 53
    • 0141790894 scopus 로고    scopus 로고
    • MHC class II signal transduction in human dendritic cells induced by a natural ligand, the LAG-3 protein (CD223)
    • Andreae S, Buisson S, Triebel F: MHC class II signal transduction in human dendritic cells induced by a natural ligand, the LAG-3 protein (CD223). Blood 2003, 102:2130-2137.
    • (2003) Blood , vol.102 , pp. 2130-2137
    • Andreae, S.1    Buisson, S.2    Triebel, F.3
  • 54
    • 35748957791 scopus 로고    scopus 로고
    • A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells
    • Brignone C, Grygar C, Marcu M, Schakel K, Triebel F: A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells. J Immunol 2007, 179:4202-4211.
    • (2007) J Immunol , vol.179 , pp. 4202-4211
    • Brignone, C.1    Grygar, C.2    Marcu, M.3    Schakel, K.4    Triebel, F.5
  • 58
    • 80155127321 scopus 로고    scopus 로고
    • Prospects for TIM3-Targeted Antitumor Immunotherapy
    • Ngiow SF, Teng MW, Smyth MJ: Prospects for TIM3-Targeted Antitumor Immunotherapy. Cancer Res 2011, 71:6567-6571.
    • (2011) Cancer Res , vol.71 , pp. 6567-6571
    • Ngiow, S.F.1    Teng, M.W.2    Smyth, M.J.3
  • 59
    • 79956103042 scopus 로고    scopus 로고
    • Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors
    • Ngiow SF, von Scheidt B, Akiba H, Yagita H, Teng MW, Smyth MJ: Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors. Cancer Res 2011, 71:3540-3551.
    • (2011) Cancer Res , vol.71 , pp. 3540-3551
    • Ngiow, S.F.1    von Scheidt, B.2    Akiba, H.3    Yagita, H.4    Teng, M.W.5    Smyth, M.J.6
  • 62
    • 77749279776 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
    • Curran MA, Montalvo W, Yagita H, Allison JP: PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci USA 2010, 107:4275-4280.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 4275-4280
    • Curran, M.A.1    Montalvo, W.2    Yagita, H.3    Allison, J.P.4
  • 65
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4 + CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY: Foxp3 programs the development and function of CD4 + CD25+ regulatory T cells. Nat Immunol 2003, 4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 66
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S: Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 69
    • 84859390119 scopus 로고    scopus 로고
    • Induced CD4 + Foxp3+ regulatory T cells in immune tolerance
    • Bilate AM, Lafaille JJ: Induced CD4 + Foxp3+ regulatory T cells in immune tolerance. Annu Rev Immunol 2012, 30:733-758.
    • (2012) Annu Rev Immunol , vol.30 , pp. 733-758
    • Bilate, A.M.1    Lafaille, J.J.2
  • 70
    • 36248976097 scopus 로고    scopus 로고
    • CD4 + CD25 + Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • Pandiyan P, Zheng L, Ishihara S, Reed J, Lenardo MJ: CD4 + CD25 + Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol 2007, 8:1353-1362.
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 72
    • 0142219250 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smadmediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis
    • Kitani A, Fuss I, Nakamura K, Kumaki F, Usui T, Strober W: Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smadmediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis. J Exp Med 2003, 198:1179-1188.
    • (2003) J Exp Med , vol.198 , pp. 1179-1188
    • Kitani, A.1    Fuss, I.2    Nakamura, K.3    Kumaki, F.4    Usui, T.5    Strober, W.6
  • 76
    • 84861783871 scopus 로고    scopus 로고
    • The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature
    • deLeeuw RJ, Kost SE, Kakal JA, Nelson BH: The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature. Clin Cancer Res 2012, 18:3022-3029.
    • (2012) Clin Cancer Res , vol.18 , pp. 3022-3029
    • deLeeuw, R.J.1    Kost, S.E.2    Kakal, J.A.3    Nelson, B.H.4
  • 77
    • 84871716970 scopus 로고    scopus 로고
    • Basic principles of tumor-associated regulatory T cell biology
    • Savage PA, Malchow S, Leventhal DS: Basic principles of tumor-associated regulatory T cell biology. Trends Immunol 2013, 34:33-40.
    • (2013) Trends Immunol , vol.34 , pp. 33-40
    • Savage, P.A.1    Malchow, S.2    Leventhal, D.S.3
  • 79
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, Nakayama E: Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res 1999, 59:3128-3133.
    • (1999) Cancer Res , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 80
    • 0346995283 scopus 로고    scopus 로고
    • Complete regression of experimental solid tumors by combination LEC/chTNT-3 immunotherapy and CD25(+) T-cell depletion
    • Li J, Hu P, Khawli LA, Epstein AL: Complete regression of experimental solid tumors by combination LEC/chTNT-3 immunotherapy and CD25(+) T-cell depletion. Cancer Res 2003, 63:8384-8392.
    • (2003) Cancer Res , vol.63 , pp. 8384-8392
    • Li, J.1    Hu, P.2    Khawli, L.A.3    Epstein, A.L.4
  • 82
    • 50949115267 scopus 로고    scopus 로고
    • Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines
    • Morse MA, Hobeika AC, Osada T, Serra D, Niedzwiecki D, Lyerly HK, Clay TM: Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines. Blood 2008, 112:610-618.
    • (2008) Blood , vol.112 , pp. 610-618
    • Morse, M.A.1    Hobeika, A.C.2    Osada, T.3    Serra, D.4    Niedzwiecki, D.5    Lyerly, H.K.6    Clay, T.M.7
  • 83
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P, Maker AV, Haworth LR, Rogers-Freezer L, Rosenberg SA: Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J Immunother 2005, 28:582-592.
    • (2005) J Immunother , vol.28 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 88
    • 79960898228 scopus 로고    scopus 로고
    • Elevated frequencies of CD4(+) CD25(+) CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia
    • Shenghui Z, Yixiang H, Jianbo W, Kang Y, Laixi B, Yan Z, Xi X: Elevated frequencies of CD4(+) CD25(+) CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia. Int J Cancer 2011, 129:1373-1381.
    • (2011) Int J Cancer , vol.129 , pp. 1373-1381
    • Shenghui, Z.1    Yixiang, H.2    Jianbo, W.3    Kang, Y.4    Laixi, B.5    Yan, Z.6    Xi, X.7
  • 90
    • 28044434385 scopus 로고    scopus 로고
    • Increased population of CD4(+)CD25(high), regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients
    • Wang X, Zheng J, Liu J, Yao J, He Y, Li X, Yu J, Yang J, Liu Z, Huang S: Increased population of CD4(+)CD25(high), regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients. Eur J Haematol 2005, 75:468-476.
    • (2005) Eur J Haematol , vol.75 , pp. 468-476
    • Wang, X.1    Zheng, J.2    Liu, J.3    Yao, J.4    He, Y.5    Li, X.6    Yu, J.7    Yang, J.8    Liu, Z.9    Huang, S.10
  • 93
    • 0023136055 scopus 로고
    • Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors
    • Young MR, Newby M, Wepsic HT: Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors. Cancer Res 1987, 47:100-105.
    • (1987) Cancer Res , vol.47 , pp. 100-105
    • Young, M.R.1    Newby, M.2    Wepsic, H.T.3
  • 94
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI: Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008, 181:5791-5802.
    • (2008) J Immunol , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 95
    • 1642536454 scopus 로고    scopus 로고
    • Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
    • Kusmartsev S, Nefedova Y, Yoder D, Gabrilovich DI: Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species. J Immunol 2004, 172:989-999.
    • (2004) J Immunol , vol.172 , pp. 989-999
    • Kusmartsev, S.1    Nefedova, Y.2    Yoder, D.3    Gabrilovich, D.I.4
  • 97
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1 + CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, Divino CM, Chen SH: Gr-1 + CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 2006, 66:1123-1131.
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 98
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumorbearing mice and improves the effect of vaccination
    • Kusmartsev S, Cheng F, Yu B, Nefedova Y, Sotomayor E, Lush R, Gabrilovich D: All-trans-retinoic acid eliminates immature myeloid cells from tumorbearing mice and improves the effect of vaccination. Cancer Res 2003, 63:4441-4449.
    • (2003) Cancer Res , vol.63 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.7
  • 100
    • 63949088142 scopus 로고    scopus 로고
    • Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells
    • Morales JK, Kmieciak M, Graham L, Feldmesser M, Bear HD, Manjili MH: Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells. Cancer Immunol Immunother 2009, 58:941-953.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 941-953
    • Morales, J.K.1    Kmieciak, M.2    Graham, L.3    Feldmesser, M.4    Bear, H.D.5    Manjili, M.H.6
  • 101
    • 84858202940 scopus 로고    scopus 로고
    • Aptamermediated blockade of IL4Ralpha triggers apoptosis of MDSCs and limits tumor progression
    • Roth F, De La Fuente AC, Vella JL, Zoso A, Inverardi L, Serafini P: Aptamermediated blockade of IL4Ralpha triggers apoptosis of MDSCs and limits tumor progression. Cancer Res 2012, 72:1373-1383.
    • (2012) Cancer Res , vol.72 , pp. 1373-1383
    • Roth, F.1    De La Fuente, A.C.2    Vella, J.L.3    Zoso, A.4    Inverardi, L.5    Serafini, P.6
  • 103
    • 0033215041 scopus 로고    scopus 로고
    • Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?
    • Mellor AL, Munn DH: Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunol Today 1999, 20:469-473.
    • (1999) Immunol Today , vol.20 , pp. 469-473
    • Mellor, A.L.1    Munn, D.H.2
  • 104
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase
    • Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB: Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase. J Exp Med 2002, 196:459-468.
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3    Damonte, G.4    Benatti, U.5    Ferrara, G.B.6
  • 106
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2, 3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D: Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2, 3-dioxygenase-mediated tryptophan degradation. Blood 2004, 103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 107
    • 0026347919 scopus 로고
    • 1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2, 3-dioxygenase
    • Cady SG, Sono M: 1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2, 3-dioxygenase. Arch Biochem Biophys 1991, 291:326-333.
    • (1991) Arch Biochem Biophys , vol.291 , pp. 326-333
    • Cady, S.G.1    Sono, M.2
  • 109
    • 58749112572 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma
    • Corm S, Berthon C, Imbenotte M, Biggio V, Lhermitte M, Dupont C, Briche I, Quesnel B: Indoleamine 2, 3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma. Leuk Res 2009, 33:490-494.
    • (2009) Leuk Res , vol.33 , pp. 490-494
    • Corm, S.1    Berthon, C.2    Imbenotte, M.3    Biggio, V.4    Lhermitte, M.5    Dupont, C.6    Briche, I.7    Quesnel, B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.