Acute myeloid leukemia cells constitutively express the immunoregulatory enzyme indoleamine 2,3-dioxygenase [3]

Leukemia

Volumn 21, Issue 2, 2007, Pages 353-355

  Curti, A ^a   Aluigi, M ^a   Pandolfi, S ^a   Ferri, E ^a   Isidori, A ^a   Salvestrini, V ^a   Durelli, I ^b   Horenstein, A L ^b   Fiore, F ^b   Massaia, M ^b   Piccioli, M ^a   Pileri, S A ^a   Zavatto, E ^a   D'Addio, A ^a   Baccarani, M ^a   Lemoli, R M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD34 ANTIGEN; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; MESSENGER RNA; TRYPTOPHAN;

ACUTE GRANULOCYTIC LEUKEMIA; CARCINOGENESIS; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; LETTER; LEUKEMIA CELL; LEUKEMOGENESIS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MIXED LYMPHOCYTE REACTION; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 33846465963     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404485     Document Type: Letter

References (6)

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3. Grohmann U, Fallarino F, Puccetti P. Tolerance, DCs and tryptophan: Much ado about IDO. Trends Immunol 2003; 24: 242-248.
4. Munn DH, Sharma MD, Lee JR, Jhaver KG, Johnson TS, Keskin DB et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 2002; 297: 1867-1870.
5. Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004; 103: 4619-4621.
6. Uyttenhove C, Pilotte L, Théate I, Stroobant V, Colau D, Parmentier N et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 2003; 9: 1269-1274.