Acidosis acts through HSP90 in a PHD/ VHL-independent manner to promote HIF function and stem cell maintenance in glioma

Cancer Research

Volumn 76, Issue 19, 2016, Pages 5845-5856

  Filatova, Alina ^a   Seidel, Sascha ^a,b   Böǧürcü, Nuray ^a   Gräf, Sabine ^a   Garvalov, Boyan K ^a   Acker, Till ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR; VON HIPPEL LINDAU PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VHL PROTEIN, HUMAN;

ACIDIFICATION; ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOGENICITY; CELL FUNCTION; CELL SELF-RENEWAL; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVITY; FEMALE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INACTIVATION; GENETIC ASSOCIATION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; GLIOMA; HUMAN; HUMAN TISSUE; HYPERCAPNIA; HYPOXIA; MOUSE; NONHUMAN; PH; PHENOTYPE; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; SIGNAL TRANSDUCTION; STEM CELL MAINTENANCE; STEM CELL NICHE; UPREGULATION; ANIMAL; BRAIN TUMOR; CANCER STEM CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ACIDOSIS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLIOMA; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; NEOPLASTIC STEM CELLS; PROLYL HYDROXYLASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84989848592     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-2630     Document Type: Article

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