-
1
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL: Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47, 2002. (Pubitemid 37328806)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
3442883664
-
Carbonic anhydrases: Current state of the art, therapeutic applications and future prospects
-
DOI 10.1080/14756360410001689540
-
Pastorekova S, Parkkila S, Pastorek J and Supuran CT: Carbonic anhydrases: current state of the art, therapeutic applications and future prospects. J Enzyme Inhib Med Chem 19: 199-229, 2004. (Pubitemid 39004275)
-
(2004)
Journal of Enzyme Inhibition and Medicinal Chemistry
, vol.19
, Issue.3
, pp. 199-229
-
-
Pastorekova, S.1
Parkkila, S.2
Pastorek, J.3
Supuran, C.T.4
-
3
-
-
0028111173
-
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
-
Pastorek J, Pastorekova S, Callebaut I, et al: Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9: 2877-2888, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 2877-2888
-
-
Pastorek, J.1
Pastorekova, S.2
Callebaut, I.3
-
4
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wykoff CC, Beasley NJ, Watson PH, et al: Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 60: 7075-7083, 2000. (Pubitemid 32059187)
-
(2000)
Cancer Research
, vol.60
, Issue.24
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.P.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
Wilson, G.D.7
Turley, H.8
Talks, K.L.9
Maxwell, P.H.10
Pugh, C.W.11
Ratcliffe, P.J.12
-
5
-
-
2542601328
-
Hypoxia inducible carbonic anhydrase IX, marker of tumor hypoxia, survival pathway and therapy target
-
Potter C and Harris AL: Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target. Cell Cycle 3: 164-167, 2004. (Pubitemid 40268690)
-
(2004)
Cell Cycle
, vol.3
, Issue.2
, pp. 164-167
-
-
Potter, C.1
Harris, A.L.2
-
6
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
DOI 10.1016/j.febslet.2004.10.043, PII S0014579304012943
-
Svastova E, Hulikova A, Rafajova M, et al: Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett 577: 439-445, 2004. (Pubitemid 39535327)
-
(2004)
FEBS Letters
, vol.577
, Issue.3
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zat'Ovicova, M.4
Gibadulinova, A.5
Casini, A.6
Cecchi, A.7
Scozzafava, A.8
Supuran, C.T.9
Pastorek, J.10
Pastorekova, S.11
-
7
-
-
78650308850
-
New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
-
Swietach P, Hulikova A, Vaughan-Jones RD and Harris AL: New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation. Oncogene 29: 6509-6521, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 6509-6521
-
-
Swietach, P.1
Hulikova, A.2
Vaughan-Jones, R.D.3
Harris, A.L.4
-
8
-
-
8844224030
-
Microenvironmental and cellular consequences of altered blood flow in tumours
-
DOI 10.1259/bjr/12913493, Angiogenesis Imaging
-
Raghunand N, Gatenby RA and Gillies RJ: Microenvironmental and cellular consequences of altered blood flow in tumours. Br J Radiol 76 Spec No 1: S11-S22, 2003. (Pubitemid 39530312)
-
(2003)
British Journal of Radiology
, vol.76
, Issue.SPEC. ISS. 1
-
-
Raghunand, N.1
Gatenby, R.A.2
Gillies, R.J.3
-
9
-
-
0142121458
-
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin
-
DOI 10.1016/S0014-4827(03)00351-3
-
Svastova E, Zilka N, Zat'ovicova M, et al: Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with beta-catenin. Exp Cell Res 290: 332-345, 2003. (Pubitemid 37272176)
-
(2003)
Experimental Cell Research
, vol.290
, Issue.2
, pp. 332-345
-
-
Svastova, E.1
Zilka, N.2
Zat'ovicova, M.3
Gibadulinova, A.4
Ciampor, F.5
Pastorek, J.6
Pastorekova, S.7
-
10
-
-
84856237720
-
Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain
-
Svastova E, Witarski W, Csaderova L, et al: Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain. J Biol Chem 287: 3392-3402, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 3392-3402
-
-
Svastova, E.1
Witarski, W.2
Csaderova, L.3
-
11
-
-
77349098742
-
Src induces expression of carbonic anhydrase IX via hypoxia-inducible factor 1
-
Takacova M, Holotnakova T, Barathova M, Pastorekova S, Kopacek J and Pastorek J: Src induces expression of carbonic anhydrase IX via hypoxia-inducible factor 1. Oncol Rep 23: 869 - 874, 2010.
-
(2010)
Oncol Rep
, vol.23
, pp. 869-874
-
-
Takacova, M.1
Holotnakova, T.2
Barathova, M.3
Pastorekova, S.4
Kopacek, J.5
Pastorek, J.6
-
12
-
-
33846562017
-
Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia
-
Ihnatko R, Kubes M, Takacova M, et al: Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia. Int J Oncol 29: 1025-1033, 2006.
-
(2006)
Int J Oncol
, vol.29
, pp. 1025-1033
-
-
Ihnatko, R.1
Kubes, M.2
Takacova, M.3
-
13
-
-
0037374179
-
Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer
-
Kaluz S, Kaluzova M and Stanbridge EJ: Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer. Cancer Res 63: 917-922, 2003. (Pubitemid 36278419)
-
(2003)
Cancer Research
, vol.63
, Issue.5
, pp. 917-922
-
-
Kaluz, S.1
Kaluzova, M.2
Stanbridge, E.J.3
-
14
-
-
31744445721
-
A versatile tool for conditional gene expression and knockdown
-
DOI 10.1038/nmeth846, PII N846
-
Szulc J, Wiznerowicz M, Sauvain MO, Trono D and Aebischer P: A versatile tool for conditional gene expression and knockdown. Nat Methods 3: 109-116, 2006. (Pubitemid 43173309)
-
(2006)
Nature Methods
, vol.3
, Issue.2
, pp. 109-116
-
-
Szulc, J.1
Wiznerowicz, M.2
Sauvain, M.-O.3
Trono, D.4
Aebischer, P.5
-
16
-
-
44449091556
-
Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia
-
Pastorekova S, Ratcliffe PJ and Pastorek J: Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia. BJU Int 101 (Suppl 4): 8-15, 2008.
-
(2008)
BJU Int
, vol.101
, Issue.SUPPL. 4
, pp. 8-15
-
-
Pastorekova, S.1
Ratcliffe, P.J.2
Pastorek, J.3
-
17
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche J, Ilc K, Laferriere J, et al: Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69: 358-368, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
-
18
-
-
71749105278
-
Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX
-
Hulikova A, Zatovicova M, Svastova E, et al: Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX. FEBS Lett 583: 3563-3568, 2009.
-
(2009)
FEBS Lett
, vol.583
, pp. 3563-3568
-
-
Hulikova, A.1
Zatovicova, M.2
Svastova, E.3
-
19
-
-
84255199558
-
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors
-
Ditte P, Dequiedt F, Svastova E, et al: Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors. Cancer Res 71: 7558-7567, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 7558-7567
-
-
Ditte, P.1
Dequiedt, F.2
Svastova, E.3
-
20
-
-
79953138420
-
Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion
-
Shin HJ, Rho SB, Jung DC, Han IO, Oh ES and Kim JY: Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion. J Cell Sci 124: 1077-1087, 2011.
-
(2011)
J Cell Sci
, vol.124
, pp. 1077-1087
-
-
Shin, H.J.1
Rho, S.B.2
Jung, D.C.3
Han, I.O.4
Oh, E.S.5
Kim, J.Y.6
-
21
-
-
0034755942
-
Molecular complexity and dynamics of cell-matrix adhesions
-
Zamir E and Geiger B: Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci 114: 3583-3590, 2001. (Pubitemid 33041040)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.20
, pp. 3583-3590
-
-
Zamir, E.1
Geiger, B.2
-
22
-
-
0037418837
-
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation
-
DOI 10.1016/S0092-8674(03)00163-6
-
Tu Y, Wu S, Shi X, Chen K and Wu C: Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. Cell 113: 37-47, 2003. (Pubitemid 36411958)
-
(2003)
Cell
, vol.113
, Issue.1
, pp. 37-47
-
-
Tu, Y.1
Wu, S.2
Shi, X.3
Chen, K.4
Wu, C.5
-
23
-
-
54549088877
-
Rac activation and inactivation control plasticity of tumor cell movement
-
Sanz-Moreno V, Gadea G, Ahn J, et al: Rac activation and inactivation control plasticity of tumor cell movement. Cell 135: 510-523, 2008.
-
(2008)
Cell
, vol.135
, pp. 510-523
-
-
Sanz-Moreno, V.1
Gadea, G.2
Ahn, J.3
-
24
-
-
0036713381
-
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
-
DOI 10.1038/ncb835
-
Meller N, Irani-Tehrani M, Kiosses WB, Del Pozo MA and Schwartz MA: Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nat Cell Biol 4: 639-647, 2002. (Pubitemid 34993699)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 639-647
-
-
Meller, N.1
Irani-Tehrani, M.2
Kiosses, W.B.3
Del Pozo, M.A.4
Schwartz, M.A.5
-
25
-
-
0037115488
-
Identification of an evolutionary conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
DOI 10.1242/jcs.00219
-
Cote JF and Vuori K: Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleo-tide exchange activity. J Cell Sci 115: 4901-4913, 2002. (Pubitemid 36054642)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.24
, pp. 4901-4913
-
-
Cote, J.-F.1
Vuori, K.2
-
26
-
-
65249168811
-
Interaction of mono-carboxylate transporter 4 with beta1-integrin and its role in cell migration
-
Gallagher SM, Castorino JJ and Philp NJ: Interaction of mono-carboxylate transporter 4 with beta1-integrin and its role in cell migration. Am J Physiol Cell Physiol 296: C414-C421, 2009.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Gallagher, S.M.1
Castorino, J.J.2
Philp, N.J.3
-
27
-
-
0037164808
-
Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1
-
DOI 10.1083/jcb.200208050
-
Denker SP and Barber DL: Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1. J Cell Biol 159: 1087-1096, 2002. (Pubitemid 36055762)
-
(2002)
Journal of Cell Biology
, vol.159
, Issue.6
, pp. 1087-1096
-
-
Denker, S.P.1
Barber, D.L.2
-
28
-
-
68149105927
-
Protons make tumor cells move like clockwork
-
Stock C and Schwab A: Protons make tumor cells move like clockwork. Pflugers Arch 458: 981-992, 2009.
-
(2009)
Pflugers Arch
, vol.458
, pp. 981-992
-
-
Stock, C.1
Schwab, A.2
-
29
-
-
1542269303
-
Integrins: Roles in cancer development and as treatment targets
-
DOI 10.1038/sj.bjc.6601576
-
Jin H and Varner J: Integrins: roles in cancer development and as treatment targets. Br J Cancer 90: 561-565, 2004. (Pubitemid 38297190)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.3
, pp. 561-565
-
-
Jin, H.1
Varner, J.2
-
30
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
DOI 10.1016/j.cardiores.2005.12.002, PII S0008636305005651
-
Nagase H, Visse R and Murphy G: Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69: 562-573, 2006. (Pubitemid 43139720)
-
(2006)
Cardiovascular Research
, vol.69
, Issue.3
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
31
-
-
59449108662
-
Matrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: A computational time-lapse study
-
Rupp PA, Visconti RP, Czirok A, Cheresh DA and Little CD: Matrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: a computational time-lapse study. Mol Biol Cell 19: 5529-5540, 2008.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5529-5540
-
-
Rupp, P.A.1
Visconti, R.P.2
Czirok, A.3
Cheresh, D.A.4
Little, C.D.5
-
32
-
-
0033547831
-
Role of His-224 in the anomalous pH dependence of human strome-lysin-1
-
Holman CM, Kan CC, Gehring MR and Van Wart HE: Role of His-224 in the anomalous pH dependence of human strome-lysin-1. Biochemistry 38: 677-681, 1999.
-
(1999)
Biochemistry
, vol.38
, pp. 677-681
-
-
Holman, C.M.1
Kan, C.C.2
Gehring, M.R.3
Van Wart, H.E.4
-
33
-
-
33947236451
-
Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen
-
DOI 10.1042/BJ20061064
-
Monaco S, Gioia M, Rodriguez J, et al: Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen. Biochem J 402: 503-513, 2007. (Pubitemid 46423887)
-
(2007)
Biochemical Journal
, vol.402
, Issue.3
, pp. 503-513
-
-
Monaco, S.1
Gioia, M.2
Rodriguez, J.3
Fasciglione, G.F.4
Di Pierro, D.5
Lupidi, G.6
Krippahl, L.7
Marini, S.8
Coletta, M.9
-
34
-
-
15844420283
-
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3
-
DOI 10.1016/S0092-8674(00)81235-0
-
Brooks PC, Stromblad S, Sanders LC, et al: Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 85: 683-693, 1996. (Pubitemid 26181048)
-
(1996)
Cell
, vol.85
, Issue.5
, pp. 683-693
-
-
Brooks, P.C.1
Stromblad, S.2
Sanders, L.C.3
Von Schalscha, T.L.4
Aimes, R.T.5
Stetler-Stevenson, W.G.6
Quigley, J.P.7
Cheresh, D.A.8
-
35
-
-
0035988813
-
Matrix-directed regulation of pericellular proteolysis and tumor progression
-
DOI 10.1016/S1044-579X(02)00026-3
-
Hornebeck W, Emonard H, Monboisse JC and Bellon G: Matrix-directed regulation of pericellular proteolysis and tumor progression. Semin Cancer Biol 12: 231-241, 2002. (Pubitemid 34833066)
-
(2002)
Seminars in Cancer Biology
, vol.12
, Issue.3
, pp. 231-241
-
-
Hornebeck, W.1
Emonard, H.2
Monboisse, J.-C.3
Bellon, G.4
-
36
-
-
21544467772
-
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and β-catenin translocation
-
DOI 10.1073/pnas.0500918102
-
Maretzky T, Reiss K, Ludwig A, et al: ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. Proc Natl Acad Sci USA 102: 9182-9187, 2005. (Pubitemid 40923538)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.26
, pp. 9182-9187
-
-
Maretzky, T.1
Reiss, K.2
Ludwig, A.3
Buchholz, J.4
Scholz, F.5
Proksch, E.6
De Strooper, B.7
Hartmann, D.8
Saftig, P.9
|