메뉴 건너뛰기




Volumn 6, Issue 9, 2015, Pages

Absence of RIPK3 predicts necroptosis resistance in malignant melanoma

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF APOPTOSIS PROTEIN; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; PROTEIN; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 3; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VEMURAFENIB; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, HUMAN;

EID: 84989306799     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.240     Document Type: Article
Times cited : (130)

References (70)
  • 1
    • 66449133280 scopus 로고    scopus 로고
    • Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
    • Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137: 1112-1123.
    • (2009) Cell , vol.137 , pp. 1112-1123
    • Cho, Y.S.1    Challa, S.2    Moquin, D.3    Genga, R.4    Ray, T.D.5    Guildford, M.6
  • 2
    • 67650812332 scopus 로고    scopus 로고
    • RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
    • Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-336.
    • (2009) Science , vol.325 , pp. 332-336
    • Zhang, D.W.1    Shao, J.2    Lin, J.3    Zhang, N.4    Lu, B.J.5    Lin, S.C.6
  • 3
    • 66749183275 scopus 로고    scopus 로고
    • Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-Alpha
    • He S, Wang L, Miao L, Wang T, Du F, Zhao L et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-Alpha. Cell 2009; 137: 1100-1111.
    • (2009) Cell , vol.137 , pp. 1100-1111
    • He, S.1    Wang, L.2    Miao, L.3    Wang, T.4    Du, F.5    Zhao, L.6
  • 4
    • 79960922705 scopus 로고    scopus 로고
    • CIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
    • Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M et al. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 2011; 43: 449-463.
    • (2011) Mol Cell , vol.43 , pp. 449-463
    • Feoktistova, M.1    Geserick, P.2    Kellert, B.3    Dimitrova, D.P.4    Langlais, C.5    Hupe, M.6
  • 5
    • 76149104286 scopus 로고    scopus 로고
    • Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
    • Geserick P, Hupe M, Moulin M, Wong WW, Feoktistova M, Kellert B et al. Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment. J Cell Biol 2009; 187: 1037-1054.
    • (2009) J Cell Biol , vol.187 , pp. 1037-1054
    • Geserick, P.1    Hupe, M.2    Moulin, M.3    Wong, W.W.4    Feoktistova, M.5    Kellert, B.6
  • 8
    • 84901257054 scopus 로고    scopus 로고
    • Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
    • Remijsen Q, Goossens V, Grootjans S, Van den Haute C, Vanlangenakker N, Dondelinger Y et al. Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis. Cell Death Dis 2014; 5: E1004.
    • (2014) Cell Death Dis , vol.5 , pp. e1004
    • Remijsen, Q.1    Goossens, V.2    Grootjans, S.3    Van Den Haute, C.4    Vanlangenakker, N.5    Dondelinger, Y.6
  • 9
    • 79960921946 scopus 로고    scopus 로고
    • The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
    • Tenev T, Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F et al. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011; 43: 432-448.
    • (2011) Mol Cell , vol.43 , pp. 432-448
    • Tenev, T.1    Bianchi, K.2    Darding, M.3    Broemer, M.4    Langlais, C.5    Wallberg, F.6
  • 10
    • 84903467736 scopus 로고    scopus 로고
    • Ars Moriendi; the art of dying well -new insights into the molecular pathways of necroptotic cell death
    • Murphy JM, Silke J. Ars Moriendi; the art of dying well -new insights into the molecular pathways of necroptotic cell death. EMBO Rep 2014; 15: 155-164.
    • (2014) EMBO Rep , vol.15 , pp. 155-164
    • Murphy, J.M.1    Silke, J.2
  • 11
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z, He S, Chen S, Liao D et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148: 213-227.
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6
  • 12
    • 84891343566 scopus 로고    scopus 로고
    • Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
    • Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2014; 16: 55-65.
    • (2014) Nat Cell Biol , vol.16 , pp. 55-65
    • Cai, Z.1    Jitkaew, S.2    Zhao, J.3    Chiang, H.C.4    Choksi, S.5    Liu, J.6
  • 13
    • 84874263775 scopus 로고    scopus 로고
    • Necroptosis: The release of damage-Associated molecular patterns and its physiological relevance
    • Kaczmarek A, Vandenabeele P, Krysko DV. Necroptosis: The release of damage-Associated molecular patterns and its physiological relevance. Immunity 2013; 38: 209-223.
    • (2013) Immunity , vol.38 , pp. 209-223
    • Kaczmarek, A.1    Vandenabeele, P.2    Krysko, D.V.3
  • 14
    • 84908072785 scopus 로고    scopus 로고
    • Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
    • Hildebrand JM, Tanzer MC, Lucet IS, Young SN, Spall SK, Sharma P et al. Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Proc Natl Acad Sci USA 2014; 111: 15072-15077.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 15072-15077
    • Hildebrand, J.M.1    Tanzer, M.C.2    Lucet, I.S.3    Young, S.N.4    Spall, S.K.5    Sharma, P.6
  • 15
    • 84905021420 scopus 로고    scopus 로고
    • Characterization of the ripoptosome and its components: Implications for anti-inflammatory and cancer therapy
    • Schilling R, Geserick P, Leverkus M. Characterization of the ripoptosome and its components: Implications for anti-inflammatory and cancer therapy. Methods Enzymol 2014; 545: 83-102.
    • (2014) Methods Enzymol , vol.545 , pp. 83-102
    • Schilling, R.1    Geserick, P.2    Leverkus, M.3
  • 17
    • 47549097367 scopus 로고    scopus 로고
    • TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha
    • Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P et al. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol 2008; 182: 171-184.
    • (2008) J Cell Biol , vol.182 , pp. 171-184
    • Vince, J.E.1    Chau, D.2    Callus, B.3    Wong, W.W.4    Hawkins, C.J.5    Schneider, P.6
  • 18
    • 84904612262 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein-A critical death resistance regulator and therapeutic target for personalized cancer therapy
    • Obexer P, Ausserlechner MJ. X-linked inhibitor of apoptosis protein-A critical death resistance regulator and therapeutic target for personalized cancer therapy. Front Oncol 2014; 4: 197.
    • (2014) Front Oncol , vol.4 , pp. 197
    • Obexer, P.1    Ausserlechner, M.J.2
  • 19
    • 84916897464 scopus 로고    scopus 로고
    • Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma
    • Spagnolo F, Ghiorzo P, Queirolo P. Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma. Oncotarget 2014; 5: 10206-10221.
    • (2014) Oncotarget , vol.5 , pp. 10206-10221
    • Spagnolo, F.1    Ghiorzo, P.2    Queirolo, P.3
  • 21
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 22
    • 42149095910 scopus 로고    scopus 로고
    • NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2
    • Diessenbacher P, Hupe M, Sprick MR, Kerstan A, Geserick P, Haas TL et al. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2. J Invest Dermatol 2008; 128: 1134-1147.
    • (2008) J Invest Dermatol , vol.128 , pp. 1134-1147
    • Diessenbacher, P.1    Hupe, M.2    Sprick, M.R.3    Kerstan, A.4    Geserick, P.5    Haas, T.L.6
  • 23
    • 72149117664 scopus 로고    scopus 로고
    • TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate nf-{kappa}b and to prevent TNF-induced apoptosis
    • Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC et al. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. J Biol Chem 2009; 284: 35906-35915.
    • (2009) J Biol Chem , vol.284 , pp. 35906-35915
    • Vince, J.E.1    Pantaki, D.2    Feltham, R.3    Mace, P.D.4    Cordier, S.M.5    Schmukle, A.C.6
  • 24
    • 84912106351 scopus 로고    scopus 로고
    • RIP3 induces apoptosis independent of pronecrotic kinase activity
    • Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell 2014; 56: 481-495.
    • (2014) Mol Cell , vol.56 , pp. 481-495
    • Mandal, P.1    Berger, S.B.2    Pillay, S.3    Moriwaki, K.4    Huang, C.5    Guo, H.6
  • 26
    • 36048999753 scopus 로고    scopus 로고
    • IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
    • Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007; 131: 669-681.
    • (2007) Cell , vol.131 , pp. 669-681
    • Varfolomeev, E.1    Blankenship, J.W.2    Wayson, S.M.3    Fedorova, A.V.4    Kayagaki, N.5    Garg, P.6
  • 27
    • 36148954336 scopus 로고    scopus 로고
    • IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
    • Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007; 131: 682-693.
    • (2007) Cell , vol.131 , pp. 682-693
    • Vince, J.E.1    Wong, W.W.2    Khan, N.3    Feltham, R.4    Chau, D.5    Ahmed, A.U.6
  • 28
    • 44949240664 scopus 로고    scopus 로고
    • CIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
    • Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008; 30: 689-700.
    • (2008) Mol Cell , vol.30 , pp. 689-700
    • Bertrand, M.J.1    Milutinovic, S.2    Dickson, K.M.3    Ho, W.C.4    Boudreault, A.5    Durkin, J.6
  • 29
    • 37549000486 scopus 로고    scopus 로고
    • A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-Alpha signaling
    • Gaither A, Porter D, Yao Y, Borawski J, Yang G, Donovan J et al. A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-Alpha signaling. Cancer Res 2007; 67: 11493-11498.
    • (2007) Cancer Res , vol.67 , pp. 11493-11498
    • Gaither, A.1    Porter, D.2    Yao, Y.3    Borawski, J.4    Yang, G.5    Donovan, J.6
  • 31
    • 33644840693 scopus 로고    scopus 로고
    • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
    • Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1: 112-119.
    • (2005) Nat Chem Biol , vol.1 , pp. 112-119
    • Degterev, A.1    Huang, Z.2    Boyce, M.3    Li, Y.4    Jagtap, P.5    Mizushima, N.6
  • 33
    • 84890534620 scopus 로고    scopus 로고
    • Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis
    • Harris PA, Bandyopadhyay D, Berger SB, Campobasso N, Capriotti CA, Cox JA et al. Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis. ACS Med Chem Lett 2013; 4: 1238-1243.
    • (2013) ACS Med Chem Lett , vol.4 , pp. 1238-1243
    • Harris, P.A.1    Bandyopadhyay, D.2    Berger, S.B.3    Campobasso, N.4    Capriotti, C.A.5    Cox, J.A.6
  • 34
    • 84886305117 scopus 로고    scopus 로고
    • Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
    • Ofengeim D, Yuan J. Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death. Nat Rev Mol Cell Biol 2013; 14: 727-736.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 727-736
    • Ofengeim, D.1    Yuan, J.2
  • 35
    • 84862866537 scopus 로고    scopus 로고
    • Upcoming strategies for the treatment of metastatic melanoma
    • Spagnolo F, Queirolo P. Upcoming strategies for the treatment of metastatic melanoma. Arch Dermatol Res 2012; 304: 177-184.
    • (2012) Arch Dermatol Res , vol.304 , pp. 177-184
    • Spagnolo, F.1    Queirolo, P.2
  • 37
    • 84903791583 scopus 로고    scopus 로고
    • The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
    • Li JX, Feng JM, Wang Y, Li XH, Chen XX, Su Y et al. The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 2014; 5: E1278.
    • (2014) Cell Death Dis , vol.5 , pp. e1278
    • Li, J.X.1    Feng, J.M.2    Wang, Y.3    Li, X.H.4    Chen, X.X.5    Su, Y.6
  • 39
    • 84907529294 scopus 로고    scopus 로고
    • Mitogen-Activated protein kinase (MAPK) hyperactivation and enhanced NRAS expression drive acquired vemurafenib resistance in V600E BRAF melanoma cells
    • Lidsky M, Antoun G, Speicher P, Adams B, Turley R, Augustine C et al. Mitogen-Activated protein kinase (MAPK) hyperactivation and enhanced NRAS expression drive acquired vemurafenib resistance in V600E BRAF melanoma cells. J Biol Chem 2014; 289: 27714-27726.
    • (2014) J Biol Chem , vol.289 , pp. 27714-27726
    • Lidsky, M.1    Antoun, G.2    Speicher, P.3    Adams, B.4    Turley, R.5    Augustine, C.6
  • 40
    • 84892769070 scopus 로고    scopus 로고
    • On the TRAIL to overcome BRAF-inhibitor resistance
    • Geserick P, Herlyn M, Leverkus M. On the TRAIL to overcome BRAF-inhibitor resistance. J Invest Dermatol 2014; 134: 315-318.
    • (2014) J Invest Dermatol , vol.134 , pp. 315-318
    • Geserick, P.1    Herlyn, M.2    Leverkus, M.3
  • 41
    • 84929083682 scopus 로고    scopus 로고
    • Antagonists of IAP proteins: Novel antitumor agents
    • Wan Y, Liu T, Hou X, Dun Y, Guan P, Fang H. Antagonists of IAP Proteins: Novel Antitumor Agents. Curr Med Chem 2014; 21: 3877-3892.
    • (2014) Curr Med Chem , vol.21 , pp. 3877-3892
    • Wan, Y.1    Liu, T.2    Hou, X.3    Dun, Y.4    Guan, P.5    Fang, H.6
  • 42
    • 84899101340 scopus 로고    scopus 로고
    • Potent and selective small-molecule inhibitors of cIAP1/2 proteins reveal that the binding of Smac mimetics to XIAP BIR3 is not required for their effective induction of cell death in tumor cells
    • Sun H, Lu J, Liu L, Yang CY, Wang S. Potent and selective small-molecule inhibitors of cIAP1/2 proteins reveal that the binding of Smac mimetics to XIAP BIR3 is not required for their effective induction of cell death in tumor cells. ACS Chem Biol 2014; 9: 994-1002.
    • (2014) ACS Chem Biol , vol.9 , pp. 994-1002
    • Sun, H.1    Lu, J.2    Liu, L.3    Yang, C.Y.4    Wang, S.5
  • 43
    • 54249159248 scopus 로고    scopus 로고
    • Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
    • Vogler M, Walczak H, Stadel D, Haas TL, Genze F, Jovanovic M et al. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res 2008; 68: 7956-7965.
    • (2008) Cancer Res , vol.68 , pp. 7956-7965
    • Vogler, M.1    Walczak, H.2    Stadel, D.3    Haas, T.L.4    Genze, F.5    Jovanovic, M.6
  • 44
    • 84925935866 scopus 로고    scopus 로고
    • The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity
    • Seigal BA, Connors WH, Fraley A, Borzilleri RM, Carter PH, Emanuel SL et al. The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity. J Med Chem 2015; 58: 2855-2861.
    • (2015) J Med Chem , vol.58 , pp. 2855-2861
    • Seigal, B.A.1    Connors, W.H.2    Fraley, A.3    Borzilleri, R.M.4    Carter, P.H.5    Emanuel, S.L.6
  • 45
    • 84897088275 scopus 로고    scopus 로고
    • Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
    • Newton K, Dugger DL, Wickliffe KE, Kapoor N, de Almagro MC, Vucic D et al. Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 2014; 343: 1357-1360.
    • (2014) Science , vol.343 , pp. 1357-1360
    • Newton, K.1    Dugger, D.L.2    Wickliffe, K.E.3    Kapoor, N.4    De Almagro, M.C.5    Vucic, D.6
  • 47
    • 84881184694 scopus 로고    scopus 로고
    • Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
    • Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013; 23: 994-1006.
    • (2013) Cell Res , vol.23 , pp. 994-1006
    • Wu, J.1    Huang, Z.2    Ren, J.3    Zhang, Z.4    He, P.5    Li, Y.6
  • 50
    • 84927660982 scopus 로고    scopus 로고
    • Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death
    • Moriwaki K, Bertin J, Gough PJ, Orlowski GM, Chan FK. Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. Cell Death Dis 2015; 6: E1636.
    • (2015) Cell Death Dis , vol.6 , pp. e1636
    • Moriwaki, K.1    Bertin, J.2    Gough, P.J.3    Orlowski, G.M.4    Chan, F.K.5
  • 51
    • 77954234849 scopus 로고    scopus 로고
    • Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome
    • Jonsson G, Busch C, Knappskog S, Geisler J, Miletic H, Ringner M et al. Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome. Clin Cancer Res 2010; 16: 3356-3367.
    • (2010) Clin Cancer Res , vol.16 , pp. 3356-3367
    • Jonsson, G.1    Busch, C.2    Knappskog, S.3    Geisler, J.4    Miletic, H.5    Ringner, M.6
  • 52
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome -biological and translational implications
    • Baylin SB, Jones PA. A decade of exploring the cancer epigenome -biological and translational implications. Nat Rev Cancer 2011; 11: 726-734.
    • (2011) Nat Rev Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 53
    • 84901422731 scopus 로고    scopus 로고
    • RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    • Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 2014; 157: 1175-1188.
    • (2014) Cell , vol.157 , pp. 1175-1188
    • Rickard, J.A.1    O'Donnell, J.A.2    Evans, J.M.3    Lalaoui, N.4    Poh, A.R.5    Rogers, T.6
  • 55
    • 79952810024 scopus 로고    scopus 로고
    • Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
    • Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011; 471: 363-367.
    • (2011) Nature , vol.471 , pp. 363-367
    • Oberst, A.1    Dillon, C.P.2    Weinlich, R.3    McCormick, L.L.4    Fitzgerald, P.5    Pop, C.6
  • 56
    • 79952780505 scopus 로고    scopus 로고
    • Functional complementation between FADD and RIP1 in embryos and lymphocytes
    • Zhang H, Zhou X, McQuade T, Li J, Chan FK, Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011; 471: 373-376.
    • (2011) Nature , vol.471 , pp. 373-376
    • Zhang, H.1    Zhou, X.2    McQuade, T.3    Li, J.4    Chan, F.K.5    Zhang, J.6
  • 57
    • 84858420051 scopus 로고    scopus 로고
    • DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA
    • Upton JW, Kaiser WJ, Mocarski ES. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 2012; 11: 290-297.
    • (2012) Cell Host Microbe , vol.11 , pp. 290-297
    • Upton, J.W.1    Kaiser, W.J.2    Mocarski, E.S.3
  • 58
    • 84055181328 scopus 로고    scopus 로고
    • Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
    • He S, Liang Y, Shao F, Wang X. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci USA 2011; 108: 20054-20059.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20054-20059
    • He, S.1    Liang, Y.2    Shao, F.3    Wang, X.4
  • 59
  • 61
    • 84906675769 scopus 로고    scopus 로고
    • Structural study of the RIPoptosome core reveals a helical assembly for kinase recruitment
    • Jang TH, Zheng C, Li J, Richards C, Hsiao YS, Walz T et al. Structural study of the RIPoptosome core reveals a helical assembly for kinase recruitment. Biochemistry 2014; 53: 5424-5431.
    • (2014) Biochemistry , vol.53 , pp. 5424-5431
    • Jang, T.H.1    Zheng, C.2    Li, J.3    Richards, C.4    Hsiao, Y.S.5    Walz, T.6
  • 62
    • 84907197966 scopus 로고    scopus 로고
    • RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
    • Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T et al. RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature 2014; 513: 95-99.
    • (2014) Nature , vol.513 , pp. 95-99
    • Takahashi, N.1    Vereecke, L.2    Bertrand, M.J.3    Duprez, L.4    Berger, S.B.5    Divert, T.6
  • 63
    • 28044469866 scopus 로고    scopus 로고
    • Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance
    • Silke J, Kratina T, Chu D, Ekert PG, Day CL, Pakusch M et al. Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. Proc Natl Acad Sci USA 2005; 102: 16182-16187.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16182-16187
    • Silke, J.1    Kratina, T.2    Chu, D.3    Ekert, P.G.4    Day, C.L.5    Pakusch, M.6
  • 64
    • 0025915427 scopus 로고
    • Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis
    • Byers HR, Etoh T, Doherty JR, Sober AJ, Mihm Jr MC. Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis. Am J Pathol 1991; 139: 423-435.
    • (1991) Am J Pathol , vol.139 , pp. 423-435
    • Byers, H.R.1    Etoh, T.2    Doherty, J.R.3    Sober, A.J.4    Mihm, M.C.5
  • 65
    • 0029242373 scopus 로고
    • Ras-GTP regulation is not altered in cultured melanocytes with reduced levels of neurofibromin derived from patients with neurofibromatosis 1 (NF1)
    • Griesser J, Kaufmann D, Eisenbarth I, Bauerle C, Krone W. Ras-GTP regulation is not altered in cultured melanocytes with reduced levels of neurofibromin derived from patients with neurofibromatosis 1 (NF1). Biol Chem Hoppe Seyler 1995; 376: 91-101.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 91-101
    • Griesser, J.1    Kaufmann, D.2    Eisenbarth, I.3    Bauerle, C.4    Krone, W.5
  • 67
    • 33744944082 scopus 로고    scopus 로고
    • Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
    • Bossen C, Ingold K, Tardivel A, Bodmer JL, Gaide O, Hertig S et al. Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem 2006; 281: 13964-13971.
    • (2006) J Biol Chem , vol.281 , pp. 13964-13971
    • Bossen, C.1    Ingold, K.2    Tardivel, A.3    Bodmer, J.L.4    Gaide, O.5    Hertig, S.6
  • 68
    • 43749119838 scopus 로고    scopus 로고
    • Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL-And CD95L-mediated apoptosis
    • Geserick P, Drewniok C, Hupe M, Haas TL, Diessenbacher P, Sprick MR et al. Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL-And CD95L-mediated apoptosis. Oncogene 2008; 27: 3211-3220.
    • (2008) Oncogene , vol.27 , pp. 3211-3220
    • Geserick, P.1    Drewniok, C.2    Hupe, M.3    Haas, T.L.4    Diessenbacher, P.5    Sprick, M.R.6
  • 69
    • 79955761920 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-And TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex
    • Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D et al. Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-And TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex. J Biol Chem 2011; 286: 16631-16646.
    • (2011) J Biol Chem , vol.286 , pp. 16631-16646
    • Kavuri, S.M.1    Geserick, P.2    Berg, D.3    Dimitrova, D.P.4    Feoktistova, M.5    Siegmund, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.