TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

Cell death & disease

Volumn 4, Issue , 2013, Pages

  Moujalled, D M ^a   Cook, W D ^b   Okamoto, T ^b   Murphy, J ^b   Lawlor, K E ^b   Vince, J E ^b   Vaux, D L ^b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE INHIBITOR; PEPTIDE CHLOROMETHYL KETONE; PROTEIN BAK; PROTEIN BAX; QUINOLINE DERIVATIVE; QUINOLINE VAL ASP(OME) CH2 OPH; QUINOLINE-VAL-ASP(OME)-CH2-OPH; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; FIBROBLAST; GENETICS; METABOLISM; MOUSE; NECROSIS; PATHOLOGY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CASPASE 8; CASPASE INHIBITORS; CELL LINE; FIBROBLASTS; MICE; NECROSIS; QUINOLINES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECOMBINANT PROTEINS; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878964122     PISSN: None     EISSN: 20414889     Source Type: None    
DOI: 10.1038/cddis.2012.201     Document Type: Article

References (0)