Cigarette smoke disrupted lung endothelial barrier integrity and increased susceptibility to acute lung injury via histone deacetylase 6

American Journal of Respiratory Cell and Molecular Biology

Volumn 54, Issue 5, 2016, Pages 683-696

  Borgas, Diana ^a   Chambers, Eboni ^a   Newton, Julie ^a   Ko, Junsuk ^a   Rivera, Stephanie ^a   Rounds, Sharon ^a   Lu, Qing ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Acute lung injury; Cigarette smoke; Endothelial cells; Histone deacetylase 6; Permeability

Indexed keywords

ACETYLCYSTEINE; ALPHA TUBULIN; CIGARETTE SMOKE; CORTACTIN; F ACTIN; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE 6; PACLITAXEL; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; VASCULAR ENDOTHELIAL CADHERIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; LIPOPOLYSACCHARIDE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DEPOLYMERIZATION; DISEASE PREDISPOSITION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ENDOTHELIUM; LUNG PARENCHYMA; MALE; MICROTUBULE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERMEABILITY BARRIER; PROTEIN CONTENT; PSEUDOMONAS; ADVERSE EFFECTS; ANIMAL; BOVINE; C57BL MOUSE; CELL MEMBRANE PERMEABILITY; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; LUNG; METABOLISM; MICROBIOLOGY; MICROVASCULATURE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PSEUDOMONAS AERUGINOSA; SMOKING; VASCULAR ENDOTHELIUM;

ACUTE LUNG INJURY; ANIMALS; CATTLE; CELL MEMBRANE PERMEABILITY; DISEASE SUSCEPTIBILITY; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GLYCOGEN SYNTHASE KINASE 3 BETA; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE, INBRED C57BL; MICROVESSELS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOMONAS AERUGINOSA; SMOKING;

EID: 84988963658     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2015-0149OC     Document Type: Article

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