In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

EMBO Journal

Volumn 21, Issue 24, 2002, Pages 6820-6831

  Matsuyama, Akihisa ^a,b   Shimazu, Tadahiro ^a,c   Sumida, Yuko ^a,b   Saito, Akiko ^c   Yoshimatsu, Yasuhiro ^c   Seigneurin Berny, Daphné ^d   Osada, Hiroyuki ^a   Komatsu, Yasuhiko ^b   Nishino, Norikazu ^b,e   Khochbin, Saadi ^d   Horinouchi, Sueharu ^c   Yoshida, Minoru ^a,b,c  

^a RIKEN   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d INSERM   (France)

^e KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Acetylation; HDAC6; Microtubule; Stability; Tubulin

Indexed keywords

ALPHA TUBULIN; ANTIMITOTIC AGENT; HISTONE DEACETYLASE; HISTONE DEACETYLASE 6; TRAPOXIN; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; DEACETYLATION; DEPOLYMERIZATION; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROTUBULE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; REGULATORY MECHANISM;

ACETYLATION; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DEMECOLCINE; ETHANOL; HISTONE DEACETYLASES; IMMUNOBLOTTING; MICE; MICROSCOPY, FLUORESCENCE; MICROTUBULES; NIH 3T3 CELLS; PEPTIDES; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; TIME FACTORS; TRANSFECTION; TUBULIN;

ANIMALIA;

EID: 12244295468     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf682     Document Type: Article

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