Effect of EGF-induced HDAC6 activation on corneal epithelial wound healing

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 6, 2010, Pages 2943-2948

  Wang, Jie ^a,b   Lin, Andrew ^a   Lu, Luo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; EPIDERMAL GROWTH FACTOR; HISTONE DEACETYLASE 6; SMALL INTERFERING RNA; TRICHOSTATIN A; HDAC6 PROTEIN, HUMAN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; MESSENGER RNA; TUBULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CORNEA EPITHELIUM; DEACETYLATION; DEBRIDEMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; WOUND HEALING; CELL CULTURE; CELL MOTION; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; ORGAN CULTURE TECHNIQUE;

BLOTTING, WESTERN; CELL MOVEMENT; CELLS, CULTURED; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EPITHELIUM, CORNEAL; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; ORGAN CULTURE TECHNIQUES; RNA, MESSENGER; RNA, SMALL INTERFERING; TUBULIN; WOUND HEALING;

EID: 77953267162     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4639     Document Type: Article

References (27)

1. Valenzuela-Fernandez A, Cabrero JR, Serrador JM, Sanchez-Madrid F. HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions. Trends Cell Biol. 2008;18:291-297.
2. Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet. 2009;10:32-42.
3. Spange S, Wagner T, Heinzel T, Kramer OH. Acetylation of nonhistone proteins modulates cellular signalling at multiple levels. Int J Biochem Cell Biol. 2009;41:185-198.
4. Zhang X, Yuan Z, Zhang Y, et al. HDAC6 modulates cell motility by altering the acetylation level of cortaction. Mol Cell. 2007;27:197-213.
5. Kovacs JJ, Murphy PJ, Gaillard S, et al. HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell. 2005;18:601-607.
6. Hubbert C, Guardiola A, Shao R, et al. HDAC6 is a microtubuleassociated deacetylase. Nature. 2002;417:455-458.
7. Zhang Y, Kwon S, Yamaguchi T, et al. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol. 2008;28:1688-1701.
8. Gao YS, Hubbert CC, Lu J, Lee YS, Lee JY, Yao TP. Histone deacetylase 6 regulates growth factor-induced action remodeling and endocytosis. Mol Cell Biol. 2007;27:8637-8647.
9. Hurst DR, Mehta A, Moore BP, et al. Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone. Biochem Biophys Res Commun. 2006;348:1429-1435.
10. Kamemura K, Ito A, Shimazu T, et al. Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells. Biochem Biophys Res Commun. 2008;374:84-89.
11. Carew JS, Giles FJ, Nawrocki ST. Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy. Cancer Lett. 2008;269:7-17.
12. Lu L, Reinach PS, Kao WW. Corneal epithelial wound healing. Exp Biol Med. 2001;226:653-664.
13. Gordon SR, Staley CA. Role of the cytoskeleton during injury induced cell migration in corneal endothelium. Cell Motil Cytoskeleton. 1990;16:47-57.
14. Nakamura M, Mishima H, Nishida T, Otori T. Requirement of microtubule assembly for initiation of EGF-stimulated corneal epithelial migration. Jpn J Ophthalmol. 1991;35:377-385.
15. Zhou Q, Wang Y, Yang L, et al. Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. Mol Vis. 2008;14:2556-2565.
16. Robertson DM, Li L, Fisher S, et al. Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line. Invest Ophthalmol Vis Sci. 2005;46:470-478.
17. Bertos NR, Gilquin B, Chan GK, Yen TJ, Khochbin S, Yang XJ. Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention. J Biol Chem. 2004;279:48246-48254.
18. Suzuki J, Chen YY, Scott GK, et al. Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression. Clin Cancer Res. 2009;15:3163-3171.
19. Cha TL, Chuang MJ, Wu ST, et al. Dual degradation of aurora A and B kinases by the histone deacetylase inhibitor LBH589 induces G2-M arrest and apoptosis of renal cancer cells. Clin Cancer Res. 2009;15:840-850.
20. Azuma K, Urano T, Horie-Inoue K, et al. Association of estrogen receptor alpha and histone deacetylase 6 causes rapid deacetylation of tubulin in breast cancer cells. Cancer Res. 2009;69:2935-2940.
21. Lee YS, Lim KH, Guo X, et al. The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. Cancer Res. 2008;68:7561-7569.
22. Gordon SR, Buxar RM. Inhibition of cytoskeletal reorganization stimulates action and tubulin syntheses during injury-induced cell migration in the corneal endothelium. J Cell Biochem. 1997;67: 409-421.
23. Teranishi S, Kimura K, Nishida T. Role of formation of an ERKFAK-paxillin complex in migration of human corneal epithelial cells during wound closure in vitro. Invest Ophthalmol Vis Sci. 2009;50:5646-5652.
24. Yin J, Yu FS. Rho kinases regulate corneal epithelial wound healing. Am J Physiol Cell Physiol. 2008;295:C378-C387.
25. Kimura K, Teranishi S, Yamauchi J, Nishida T. Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure. Invest Ophthalmol Vis Sci. 2008;49:125-132.
26. Shan B, Yao TP, Nguyen HT, et al. Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition. J Biol Chem. 2008;283:21065-21073.
27. Matsuyama A, Shimazu T, Sumida Y, et al. In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J. 2002;21:6820-6831.