-
1
-
-
78149386734
-
Tumor initiation and progression in hepatocellular carcinoma: Risk factors, classification, and therapeutic targets
-
Severi T, van Malenstein H, Verslype C, van Pelt JF Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets. Acta Pharmacol Sin 31: 1409-1420.
-
Acta Pharmacol Sin
, vol.31
, pp. 1409-1420
-
-
Severi, T.1
Van Malenstein, H.2
Verslype, C.3
Van Pelt, J.F.4
-
2
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
3
-
-
80052358980
-
Therapeutic strategies for the clinical blockade of IL-6/ gp130 signaling
-
Jones SA, Scheller J, Rose-John S. Therapeutic strategies for the clinical blockade of IL-6/ gp130 signaling. J Clin Invest 2011; 121: 3375-3383.
-
(2011)
J Clin Invest
, vol.121
, pp. 3375-3383
-
-
Jones, S.A.1
Scheller, J.2
Rose-John, S.3
-
4
-
-
0036584028
-
Development of anti-TNF therapy for rheumatoid arthritis
-
Feldmann M. Development of anti-TNF therapy for rheumatoid arthritis. Nat Rev Immunol 2002; 2: 364-371.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 364-371
-
-
Feldmann, M.1
-
5
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
McInnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 2007; 7: 429-442.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
6
-
-
9044222888
-
Targeted disruption of gp130, a common signal transducer for the Interleukin 6 family of cytokines, leads to myocardial and hematological disorders
-
Yoshida K, Taga T, Saito M, Suematsu S, Kumanogoh A, Tanaka T et al. Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci USA 1996; 93: 407-411.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 407-411
-
-
Yoshida, K.1
Taga, T.2
Saito, M.3
Suematsu, S.4
Kumanogoh, A.5
Tanaka, T.6
-
7
-
-
78649741783
-
Gp130 at the nexus of inflammation, autoimmunity, and cancer
-
Silver JS, Hunter CA. gp130 at the nexus of inflammation, autoimmunity, and cancer. J Leukoc Biol 2010; 88: 1145-1156.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 1145-1156
-
-
Silver, J.S.1
Hunter, C.A.2
-
8
-
-
0038609651
-
Hexameric structure and assembly of the Interleukin-6/IL-6 alpha-receptor/gp130 complex
-
Boulanger MJ, Chow DC, Brevnova EE, Garcia KC. Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex. Science 2003; 300: 2101-2104.
-
(2003)
Science
, vol.300
, pp. 2101-2104
-
-
Boulanger, M.J.1
Chow, D.C.2
Brevnova, E.E.3
Garcia, K.C.4
-
9
-
-
0028281794
-
Association and activation of jak-tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
-
Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA et al. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. Science 1994; 263: 92-95.
-
(1994)
Science
, vol.263
, pp. 92-95
-
-
Stahl, N.1
Boulton, T.G.2
Farruggella, T.3
Ip, N.Y.4
Davis, S.5
Witthuhn, B.A.6
-
10
-
-
0028296179
-
Association of transcription factor APRF and protein kinase jak1 with the Interleukin-6 signal transducer gp130
-
Lutticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A et al. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science 1994; 263: 89-92.
-
(1994)
Science
, vol.263
, pp. 89-92
-
-
Lutticken, C.1
Wegenka, U.M.2
Yuan, J.3
Buschmann, J.4
Schindler, C.5
Ziemiecki, A.6
-
11
-
-
0043167910
-
Lack of gp130 expression in hepatocytes promotes liver injury
-
Streetz KL, Wustefeld T, Klein C, Kallen KJ, Tronche F, Betz UA et al. Lack of gp130 expression in hepatocytes promotes liver injury. Gastroenterology 2003; 125: 532-543.
-
(2003)
Gastroenterology
, vol.125
, pp. 532-543
-
-
Streetz, K.L.1
Wustefeld, T.2
Klein, C.3
Kallen, K.J.4
Tronche, F.5
Betz, U.A.6
-
12
-
-
0037784230
-
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases
-
Streetz KL, Tacke F, Leifeld L, Wustefeld T, Graw A, Klein C et al. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. Hepatology 2003; 38: 218-229.
-
(2003)
Hepatology
, vol.38
, pp. 218-229
-
-
Streetz, K.L.1
Tacke, F.2
Leifeld, L.3
Wustefeld, T.4
Graw, A.5
Klein, C.6
-
13
-
-
51549089438
-
Gp130 signaling promotes development of acute experimental colitis by facilitating early neutrophil/ macrophage recruitment and activation
-
Sander LE, Obermeier F, Dierssen U, Kroy DC, Singh AK, Seidler U et al. Gp130 signaling promotes development of acute experimental colitis by facilitating early neutrophil/ macrophage recruitment and activation. J Immunol 2008; 181: 3586-3594.
-
(2008)
J Immunol
, vol.181
, pp. 3586-3594
-
-
Sander, L.E.1
Obermeier, F.2
Dierssen, U.3
Kroy, D.C.4
Singh, A.K.5
Seidler, U.6
-
14
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM et al. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 2007; 317: 121-124.
-
(2007)
Science
, vol.317
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
-
15
-
-
9644254191
-
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
-
Lee JS, Chu IS, Mikaelyan A, Calvisi DF, Heo J, Reddy JK et al. Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genet 2004; 36: 1306-1311.
-
(2004)
Nat Genet
, vol.36
, pp. 1306-1311
-
-
Lee, J.S.1
Chu, I.S.2
Mikaelyan, A.3
Calvisi, D.F.4
Heo, J.5
Reddy, J.K.6
-
16
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA doublestrand breaks
-
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA doublestrand breaks. Cell 2005; 123: 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
17
-
-
84856866918
-
DNA damage induces reactive oxygen species generation through the H2AX-nox1/Rac1 pathway
-
Kang MA, So EY, Simons AL, Spitz DR, Ouchi T. DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway. Cell Death Dis 2012; 3: e249.
-
(2012)
Cell Death Dis
, vol.3
, pp. e249
-
-
Kang, M.A.1
So, E.Y.2
Simons, A.L.3
Spitz, D.R.4
Ouchi, T.5
-
18
-
-
63849187827
-
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
-
Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 2009; 458: 591-596.
-
(2009)
Nature
, vol.458
, pp. 591-596
-
-
Cook, P.J.1
Ju, B.G.2
Telese, F.3
Wang, X.4
Glass, C.K.5
Rosenfeld, M.G.6
-
19
-
-
77956409919
-
IL-6, a risk factor for hepatocellular carcinoma: Flll32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells
-
Liu Y, Fuchs J, Li C, Lin J. IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells. Cell Cycle 2010; 9: 3423-3427.
-
(2010)
Cell Cycle
, vol.9
, pp. 3423-3427
-
-
Liu, Y.1
Fuchs, J.2
Li, C.3
Lin, J.4
-
20
-
-
0001929693
-
Cytokines in acute and chronic inflammation
-
Feghali CA, Wright TM. Cytokines in acute and chronic inflammation. Front Biosci 1997; 2: d12-d26.
-
(1997)
Front Biosci
, vol.2
, pp. d12-d26
-
-
Feghali, C.A.1
Wright, T.M.2
-
21
-
-
84859968478
-
Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes Interleukin 11 signaling
-
Sommer J, Effenberger T, Volpi E, Waetzig GH, Bernhardt M, Suthaus J et al. Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling. J Biol Chem 2012; 287: 13743-13751.
-
(2012)
J Biol Chem
, vol.287
, pp. 13743-13751
-
-
Sommer, J.1
Effenberger, T.2
Volpi, E.3
Waetzig, G.H.4
Bernhardt, M.5
Suthaus, J.6
-
22
-
-
68849118378
-
Experimental mouse models for hepatocellular carcinoma research
-
Heindryckx F, Colle I, Van Vlierberghe H. Experimental mouse models for hepatocellular carcinoma research. Int J Exp Pathol 2009; 90: 367-386.
-
(2009)
Int J Exp Pathol
, vol.90
, pp. 367-386
-
-
Heindryckx, F.1
Colle, I.2
Van Vlierberghe, H.3
-
23
-
-
77955404832
-
DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation
-
Wang H, Yang ES, Jiang J, Nowsheen S, Xia F. DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation. Cancer Res 2010; 70: 6258-6267.
-
(2010)
Cancer Res
, vol.70
, pp. 6258-6267
-
-
Wang, H.1
Yang, E.S.2
Jiang, J.3
Nowsheen, S.4
Xia, F.5
-
24
-
-
33745265207
-
Reactive oxygen species: Role in the development of cancer and various chronic conditions
-
Waris G, Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. J Carcinog 2006; 5: 14.
-
(2006)
J Carcinog
, vol.5
, pp. 14
-
-
Waris, G.1
Ahsan, H.2
-
25
-
-
78650859531
-
NF-kappaB and STAT3 - Key players in liver inflammation and cancer
-
He G, Karin M. NF-kappaB and STAT3 - key players in liver inflammation and cancer. Cell Res 2011; 21: 159-168.
-
(2011)
Cell Res
, vol.21
, pp. 159-168
-
-
He, G.1
Karin, M.2
-
26
-
-
74549217325
-
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T et al. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 17: 286-297.
-
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
-
27
-
-
83455162844
-
IL-17 induces AKT-dependent IL-6/ JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma
-
Gu FM, Li QL, Gao Q, Jiang JH, Zhu K, Huang XY et al. IL-17 induces AKT-dependent IL-6/ JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Cancer 10: 150.
-
Mol Cancer
, vol.10
, pp. 150
-
-
Gu, F.M.1
Li, Q.L.2
Gao, Q.3
Jiang, J.H.4
Zhu, K.5
Huang, X.Y.6
-
28
-
-
84890427346
-
Serine 727 phosphorylation of STAT3: An early change in mouse hepatocarcinogenesis induced by neonatal treatment with diethylnitrosamine
-
Miyakoshi M, Yamamoto M, Tanaka H, Ogawa K. Serine 727 phosphorylation of STAT3: an early change in mouse hepatocarcinogenesis induced by neonatal treatment with diethylnitrosamine. Mol Carcinog 2014; 53: 67-76.
-
(2014)
Mol Carcinog
, vol.53
, pp. 67-76
-
-
Miyakoshi, M.1
Yamamoto, M.2
Tanaka, H.3
Ogawa, K.4
-
29
-
-
65549094595
-
Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation
-
Hosui A, Kimura A, Yamaji D, Zhu BM, Na R, Hennighausen L. Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation. J Exp Med 2009; 206: 819-831.
-
(2009)
J Exp Med
, vol.206
, pp. 819-831
-
-
Hosui, A.1
Kimura, A.2
Yamaji, D.3
Zhu, B.M.4
Na, R.5
Hennighausen, L.6
-
30
-
-
80053311826
-
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice
-
Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H et al. Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. Hepatology 2011; 54: 1398-1409.
-
(2011)
Hepatology
, vol.54
, pp. 1398-1409
-
-
Mueller, K.M.1
Kornfeld, J.W.2
Friedbichler, K.3
Blaas, L.4
Egger, G.5
Esterbauer, H.6
-
31
-
-
0029005549
-
Constitutively activated jak-STAT pathway in T cells transformed with HTLV-I
-
Migone TS, Lin JX, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G et al. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science 1995; 269: 79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.S.1
Lin, J.X.2
Cereseto, A.3
Mulloy, J.C.4
O'Shea, J.J.5
Franchini, G.6
-
32
-
-
0033180185
-
Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells
-
Moriggl R, Sexl V, Piekorz R, Topham D, Ihle JN. Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells. Immunity 1999; 11: 225-230.
-
(1999)
Immunity
, vol.11
, pp. 225-230
-
-
Moriggl, R.1
Sexl, V.2
Piekorz, R.3
Topham, D.4
Ihle, J.N.5
-
33
-
-
0033082138
-
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
-
Moriggl R, Topham DJ, Teglund S, Sexl V, McKay C, Wang D et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 1999; 10: 249-259.
-
(1999)
Immunity
, vol.10
, pp. 249-259
-
-
Moriggl, R.1
Topham, D.J.2
Teglund, S.3
Sexl, V.4
McKay, C.5
Wang, D.6
-
34
-
-
33749000324
-
Rac activation is associated with hepatocellular carcinoma metastasis by up-regulation of vascular endothelial growth factor expression
-
Lee TK, Poon RT, Yuen AP, Man K, Yang ZF, Guan XY et al. Rac activation is associated with hepatocellular carcinoma metastasis by up-regulation of vascular endothelial growth factor expression. Clin Cancer Res 2006; 12: 5082-5089.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5082-5089
-
-
Lee, T.K.1
Poon, R.T.2
Yuen, A.P.3
Man, K.4
Yang, Z.F.5
Guan, X.Y.6
-
35
-
-
74549217325
-
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T et al. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 2010; 17: 286-297.
-
(2010)
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
-
36
-
-
33847769909
-
Hormonal treatment of human hepatocellular carcinoma
-
Di Maio M, De Maio E, Morabito A, D'Aniello R, De Feo G, Gallo C et al. Hormonal treatment of human hepatocellular carcinoma. Ann N Y Acad Sci 2006; 1089: 252-261.
-
(2006)
Ann N y Acad Sci
, vol.1089
, pp. 252-261
-
-
Di Maio, M.1
De Maio, E.2
Morabito, A.3
D'Aniello, R.4
De Feo, G.5
Gallo, C.6
-
37
-
-
0034712832
-
Mutations in the tumor suppressors smad2 and smad4 inactivate transforming growth factor beta signaling by targeting smads to the ubiquitin-proteasome pathway
-
Xu J, Attisano L. Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 2000; 97: 4820-4825.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4820-4825
-
-
Xu, J.1
Attisano, L.2
-
38
-
-
82655183784
-
STAT3 activation in monocytes accelerates liver cancer progression
-
Wu WY, Li J, Wu ZS, Zhang CL, Meng XL. STAT3 activation in monocytes accelerates liver cancer progression. BMC Cancer 2011; 11: 506.
-
(2011)
BMC Cancer
, vol.11
, pp. 506
-
-
Wu, W.Y.1
Li, J.2
Wu, Z.S.3
Zhang, C.L.4
Meng, X.L.5
-
39
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
40
-
-
54449083925
-
Molecular targeted therapies in hepatocellular carcinoma
-
Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 2008; 48: 1312-1327.
-
(2008)
Hepatology
, vol.48
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
-
41
-
-
24144485856
-
Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130
-
Howlett M, Judd LM, Jenkins B, La Gruta NL, Grail D, Ernst M et al. Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130. Gastroenterology 2005; 129: 1005-1018.
-
(2005)
Gastroenterology
, vol.129
, pp. 1005-1018
-
-
Howlett, M.1
Judd, L.M.2
Jenkins, B.3
La Gruta, N.L.4
Grail, D.5
Ernst, M.6
-
42
-
-
43049096401
-
STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
-
Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H et al. STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest 2008; 118: 1727-1738.
-
(2008)
J Clin Invest
, vol.118
, pp. 1727-1738
-
-
Ernst, M.1
Najdovska, M.2
Grail, D.3
Lundgren-May, T.4
Buchert, M.5
Tye, H.6
-
43
-
-
58149326854
-
Frequent inframe somatic deletions activate gp130 in inflammatory hepatocellular tumours
-
Rebouissou S, Amessou M, Couchy G, Poussin K, Imbeaud S, Pilati C et al. Frequent inframe somatic deletions activate gp130 in inflammatory hepatocellular tumours. Nature 2009; 457: 200-204.
-
(2009)
Nature
, vol.457
, pp. 200-204
-
-
Rebouissou, S.1
Amessou, M.2
Couchy, G.3
Poussin, K.4
Imbeaud, S.5
Pilati, C.6
-
44
-
-
33845865825
-
Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
-
Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007; 7: 41-51.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
45
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009; 9: 798-809.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
46
-
-
84868115643
-
Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer
-
Johnson C, Han Y, Hughart N, McCarra J, Alpini G, Meng F. Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer. Transl Gastrointest Cancer 1: 58-70.
-
Transl Gastrointest Cancer
, vol.1
, pp. 58-70
-
-
Johnson, C.1
Han, Y.2
Hughart, N.3
McCarra, J.4
Alpini, G.5
Meng, F.6
-
47
-
-
59849099695
-
Role of sex steroid receptors in pathobiology of hepatocellular carcinoma
-
Kalra M, Mayes J, Assefa S, Kaul AK, Kaul R. Role of sex steroid receptors in pathobiology of hepatocellular carcinoma. World J Gastroenterol 2008; 14: 5945-5961.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 5945-5961
-
-
Kalra, M.1
Mayes, J.2
Assefa, S.3
Kaul, A.K.4
Kaul, R.5
-
48
-
-
0033529704
-
Stat3 as an oncogene
-
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C et al. Stat3 as an oncogene. Cell 1999; 98: 295-303.
-
(1999)
Cell
, vol.98
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
-
49
-
-
84867785470
-
Peptide-functionalized gold nanorods increase liver injury in hepatitis
-
Bartneck M, Ritz T, Keul HA, Wambach M, Bornemann J, Gbureck U et al. Peptide-functionalized gold nanorods increase liver injury in hepatitis. ACS Nano 2012; 6: 8767-8777.
-
(2012)
ACS Nano
, vol.6
, pp. 8767-8777
-
-
Bartneck, M.1
Ritz, T.2
Keul, H.A.3
Wambach, M.4
Bornemann, J.5
Gbureck, U.6
-
50
-
-
0034042794
-
Mechanistic basis for nonlinearities and thresholds in rat liver carcinogenesis by the DNA-reactive carcinogens 2-acetylaminofluorene and diethylnitrosamine
-
Williams GM, Iatropoulos MJ, Jeffrey AM. Mechanistic basis for nonlinearities and thresholds in rat liver carcinogenesis by the DNA-reactive carcinogens 2-acetylaminofluorene and diethylnitrosamine. Toxicol Pathol 2000; 28: 388-395.
-
(2000)
Toxicol Pathol
, vol.28
, pp. 388-395
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Jeffrey, A.M.3
-
51
-
-
18844447266
-
Oncostatin M induces an acute phase response but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture
-
Matthews VB, Knight B, Tirnitz-Parker JE, Boon J, Olynyk JK, Yeoh GC. Oncostatin M induces an acute phase response but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture. Exp Cell Res 2005; 306: 252-263.
-
(2005)
Exp Cell Res
, vol.306
, pp. 252-263
-
-
Matthews, V.B.1
Knight, B.2
Tirnitz-Parker, J.E.3
Boon, J.4
Olynyk, J.K.5
Yeoh, G.C.6
-
52
-
-
84862909192
-
Foxa1 and foxa2 are essential for sexual dimorphism in liver cancer
-
Li Z, Tuteja G, Schug J, Kaestner KH. Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell 2012; 148: 72-83.
-
(2012)
Cell
, vol.148
, pp. 72-83
-
-
Li, Z.1
Tuteja, G.2
Schug, J.3
Kaestner, K.H.4
-
53
-
-
34447328059
-
Cancer. Sex, cytokines, and cancer
-
Lawrence T, Hageman T, Balkwill F. Cancer. Sex, cytokines, and cancer. Science 2007; 317: 51-52.
-
(2007)
Science
, vol.317
, pp. 51-52
-
-
Lawrence, T.1
Hageman, T.2
Balkwill, F.3
-
54
-
-
84885419703
-
TNFR1 determines progression of chronic liver injury in the IKKgamma/Nemo genetic model
-
Cubero FJ, Singh A, Borkham-Kamphorst E, Nevzorova YA, Al Masaoudi M, Haas U et al. TNFR1 determines progression of chronic liver injury in the IKKgamma/Nemo genetic model. Cell Death Differ 2013; 20: 1580-1592.
-
(2013)
Cell Death Differ
, vol.20
, pp. 1580-1592
-
-
Cubero, F.J.1
Singh, A.2
Borkham-Kamphorst, E.3
Nevzorova, Y.A.4
Al Masaoudi, M.5
Haas, U.6
-
55
-
-
46249134069
-
Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice
-
Teoh NC, Dan YY, Swisshelm K, Lehman S, Wright JH, Haque J et al. Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology 2008; 47: 2078-2088.
-
(2008)
Hepatology
, vol.47
, pp. 2078-2088
-
-
Teoh, N.C.1
Dan, Y.Y.2
Swisshelm, K.3
Lehman, S.4
Wright, J.H.5
Haque, J.6
-
56
-
-
0026406073
-
Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma
-
Ito N, Kawata S, Tamura S, Takaishi K, Shirai Y, Kiso S et al. Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma. Cancer Res 1991; 51: 4080-4083.
-
(1991)
Cancer Res
, vol.51
, pp. 4080-4083
-
-
Ito, N.1
Kawata, S.2
Tamura, S.3
Takaishi, K.4
Shirai, Y.5
Kiso, S.6
-
57
-
-
52649109063
-
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells
-
Cohen PA, Koski GK, Czerniecki BJ, Bunting KD, Fu XY, Wang Z et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood 2008; 112: 1832-1843.
-
(2008)
Blood
, vol.112
, pp. 1832-1843
-
-
Cohen, P.A.1
Koski, G.K.2
Czerniecki, B.J.3
Bunting, K.D.4
Fu, X.Y.5
Wang, Z.6
-
58
-
-
79951682333
-
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
-
Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR et al. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat Immunol 2011; 12: 247-254.
-
(2011)
Nat Immunol
, vol.12
, pp. 247-254
-
-
Yang, X.P.1
Ghoreschi, K.2
Steward-Tharp, S.M.3
Rodriguez-Canales, J.4
Zhu, J.5
Grainger, J.R.6
-
59
-
-
0032539008
-
Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects
-
Betz UA, Bloch W, van den Broek M, Yoshida K, Taga T, Kishimoto T et al. Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects. J Exp Med 1998; 188: 1955-1965.
-
(1998)
J Exp Med
, vol.188
, pp. 1955-1965
-
-
Betz, U.A.1
Bloch, W.2
Van Den Broek, M.3
Yoshida, K.4
Taga, T.5
Kishimoto, T.6
|