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Volumn 148, Issue 1-2, 2012, Pages 72-83

Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; DIETHYLNITROSAMINE; ESTROGEN RECEPTOR ALPHA; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA;

EID: 84862909192     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.11.026     Document Type: Article
Times cited : (316)

References (60)
  • 1
    • 49149090637 scopus 로고    scopus 로고
    • Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress
    • I.M. Bochkis, N.E. Rubins, P. White, E.E. Furth, J.R. Friedman, and K.H. Kaestner Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress Nat. Med. 14 2008 828 836
    • (2008) Nat. Med. , vol.14 , pp. 828-836
    • Bochkis, I.M.1    Rubins, N.E.2    White, P.3    Furth, E.E.4    Friedman, J.R.5    Kaestner, K.H.6
  • 5
    • 33750438123 scopus 로고    scopus 로고
    • The Foxa family of transcription factors in development and metabolism
    • DOI 10.1007/s00018-006-6095-6
    • J.R. Friedman, and K.H. Kaestner The Foxa family of transcription factors in development and metabolism Cell. Mol. Life Sci. 63 2006 2317 2328 (Pubitemid 44653042)
    • (2006) Cellular and Molecular Life Sciences , vol.63 , Issue.19-20 , pp. 2317-2328
    • Friedman, J.R.1    Kaestner, K.H.2
  • 6
    • 58049204234 scopus 로고    scopus 로고
    • Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
    • N. Gao, J. LeLay, M.Z. Vatamaniuk, S. Rieck, J.R. Friedman, and K.H. Kaestner Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development Genes Dev. 22 2008 3435 3448
    • (2008) Genes Dev. , vol.22 , pp. 3435-3448
    • Gao, N.1    Lelay, J.2    Vatamaniuk, M.Z.3    Rieck, S.4    Friedman, J.R.5    Kaestner, K.H.6
  • 7
    • 64549114508 scopus 로고    scopus 로고
    • Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
    • N. Gao, P. White, and K.H. Kaestner Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2 Dev. Cell 16 2009 588 599
    • (2009) Dev. Cell , vol.16 , pp. 588-599
    • Gao, N.1    White, P.2    Kaestner, K.H.3
  • 8
    • 0042266417 scopus 로고    scopus 로고
    • The role of hepatocyte nuclear factor-3α (forkhead box A1) and androgen receptor in transcriptional regulation of prostatic genes
    • DOI 10.1210/me.2003-0020
    • N. Gao, J. Zhang, M.A. Rao, T.C. Case, J. Mirosevich, Y. Wang, R. Jin, A. Gupta, P.S. Rennie, and R.J. Matusik The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes Mol. Endocrinol. 17 2003 1484 1507 (Pubitemid 36930465)
    • (2003) Molecular Endocrinology , vol.17 , Issue.8 , pp. 1484-1507
    • Gao, N.1    Zhang, J.2    Rao, M.A.3    Case, T.C.4    Mirosevich, J.5    Wang, Y.6    Jin, R.7    Gupta, A.8    Rennie, P.S.9    Matusik, R.J.10
  • 10
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • S. Heinz, C. Benner, N. Spann, E. Bertolino, Y.C. Lin, P. Laslo, J.X. Cheng, C. Murre, H. Singh, and C.K. Glass Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities Mol. Cell 38 2010 576 589
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6    Cheng, J.X.7    Murre, C.8    Singh, H.9    Glass, C.K.10
  • 12
    • 25444449223 scopus 로고    scopus 로고
    • The making of the liver: Developmental competence in foregut endoderm and induction of the hepatogenic program
    • K.H. Kaestner The making of the liver: developmental competence in foregut endoderm and induction of the hepatogenic program Cell Cycle 4 2005 1146 1148 (Pubitemid 41365379)
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1146-1148
    • Kaestner, K.H.1
  • 13
    • 77956649260 scopus 로고    scopus 로고
    • The FoxA factors in organogenesis and differentiation
    • K.H. Kaestner The FoxA factors in organogenesis and differentiation Curr. Opin. Genet. Dev. 20 2010 527 532
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 527-532
    • Kaestner, K.H.1
  • 14
    • 0031834339 scopus 로고    scopus 로고
    • Targeted disruption of the gene encoding hepatocyte nuclear factor 3γ results in reduced transcription of hepatocyte-specific genes
    • K.H. Kaestner, H. Hiemisch, and G. Schutz Targeted disruption of the gene encoding hepatocyte nuclear factor 3gamma results in reduced transcription of hepatocyte-specific genes Mol. Cell. Biol. 18 1998 4245 4251 (Pubitemid 28287947)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.7 , pp. 4245-4251
    • Kaestner, K.H.1    Hiemisch, H.2    Schutz, G.3
  • 15
    • 0033557490 scopus 로고    scopus 로고
    • Inactivation of the winged helix transcription factor HNF3α affects glucose homeostasis and islet glucagon gene expression in vivo
    • K.H. Kaestner, J. Katz, Y. Liu, D.J. Drucker, and G. Schutz Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo Genes Dev. 13 1999 495 504 (Pubitemid 29108764)
    • (1999) Genes and Development , vol.13 , Issue.4 , pp. 495-504
    • Kaestner, K.H.1    Katz, J.2    Liu, Y.3    Drucker, D.J.4    Schutz, G.5
  • 16
    • 59849099695 scopus 로고    scopus 로고
    • Role of sex steroid receptors in pathobiology of hepatocellular carcinoma
    • M. Kalra, J. Mayes, S. Assefa, A.K. Kaul, and R. Kaul Role of sex steroid receptors in pathobiology of hepatocellular carcinoma World J. Gastroenterol. 14 2008 5945 5961
    • (2008) World J. Gastroenterol. , vol.14 , pp. 5945-5961
    • Kalra, M.1    Mayes, J.2    Assefa, S.3    Kaul, A.K.4    Kaul, R.5
  • 18
    • 34447328059 scopus 로고    scopus 로고
    • Cancer. Sex, cytokines, and cancer
    • T. Lawrence, T. Hageman, and F. Balkwill Cancer. Sex, cytokines, and cancer Science 317 2007 51 52
    • (2007) Science , vol.317 , pp. 51-52
    • Lawrence, T.1    Hageman, T.2    Balkwill, F.3
  • 19
    • 20544473735 scopus 로고    scopus 로고
    • The initiation of liver development is dependent on Foxa transcription factors
    • DOI 10.1038/nature03649
    • C.S. Lee, J.R. Friedman, J.T. Fulmer, and K.H. Kaestner The initiation of liver development is dependent on Foxa transcription factors Nature 435 2005 944 947 (Pubitemid 40896319)
    • (2005) Nature , vol.435 , Issue.7044 , pp. 944-947
    • Lee, C.S.1    Friedman, J.R.2    Fulmer, J.T.3    Kaestner, K.H.4
  • 20
    • 9644254191 scopus 로고    scopus 로고
    • Application of comparative functional genomics to identify best-fit mouse models to study human cancer
    • DOI 10.1038/ng1481
    • J.S. Lee, I.S. Chu, A. Mikaelyan, D.F. Calvisi, J. Heo, J.K. Reddy, and S.S. Thorgeirsson Application of comparative functional genomics to identify best-fit mouse models to study human cancer Nat. Genet. 36 2004 1306 1311 (Pubitemid 39577940)
    • (2004) Nature Genetics , vol.36 , Issue.12 , pp. 1306-1311
    • Lee, J.-S.1    Chu, I.-S.2    Mikaelyan, A.3    Calvisi, D.F.4    Heo, J.5    Reddy, J.K.6    Thorgeirsson, S.S.7
  • 23
    • 36849018082 scopus 로고    scopus 로고
    • Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant
    • DOI 10.1016/j.bbrc.2007.11.069, PII S0006291X07024345
    • Z. Liu, and C. Ukomadu Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant Biochem. Biophys. Res. Commun. 365 2008 729 734 (Pubitemid 350234851)
    • (2008) Biochemical and Biophysical Research Communications , vol.365 , Issue.4 , pp. 729-734
    • Liu, Z.1    Ukomadu, C.2
  • 24
    • 40849085514 scopus 로고    scopus 로고
    • FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription
    • DOI 10.1016/j.cell.2008.01.018, PII S0092867408001189
    • M. Lupien, J. Eeckhoute, C.A. Meyer, Q. Wang, Y. Zhang, W. Li, J.S. Carroll, X.S. Liu, and M. Brown FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription Cell 132 2008 958 970 (Pubitemid 351391952)
    • (2008) Cell , vol.132 , Issue.6 , pp. 958-970
    • Lupien, M.1    Eeckhoute, J.2    Meyer, C.A.3    Wang, Q.4    Zhang, Y.5    Li, W.6    Carroll, J.S.7    Liu, X.S.8    Brown, M.9
  • 25
    • 51249105211 scopus 로고    scopus 로고
    • Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma
    • e941-e945
    • W.L. Ma, C.L. Hsu, M.H. Wu, C.T. Wu, C.C. Wu, J.J. Lai, Y.S. Jou, C.W. Chen, S. Yeh, and C. Chang Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma Gastroenterology 135 2008 947 955 e941-e945
    • (2008) Gastroenterology , vol.135 , pp. 947-955
    • Ma, W.L.1    Hsu, C.L.2    Wu, M.H.3    Wu, C.T.4    Wu, C.C.5    Lai, J.J.6    Jou, Y.S.7    Chen, C.W.8    Yeh, S.9    Chang, C.10
  • 26
    • 70350239859 scopus 로고    scopus 로고
    • Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively
    • R. May, S.M. Sureban, N. Hoang, T.E. Riehl, S.A. Lightfoot, R. Ramanujam, J.H. Wyche, S. Anant, and C.W. Houchen Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively Stem Cells 27 2009 2571 2579
    • (2009) Stem Cells , vol.27 , pp. 2571-2579
    • May, R.1    Sureban, S.M.2    Hoang, N.3    Riehl, T.E.4    Lightfoot, S.A.5    Ramanujam, R.6    Wyche, J.H.7    Anant, S.8    Houchen, C.W.9
  • 27
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • DOI 10.1126/science.1140485
    • W.E. Naugler, T. Sakurai, S. Kim, S. Maeda, K. Kim, A.M. Elsharkawy, and M. Karin Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production Science 317 2007 121 124 (Pubitemid 47056470)
    • (2007) Science , vol.317 , Issue.5834 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3    Maeda, S.4    Kim, K.5    Elsharkawy, A.M.6    Karin, M.7
  • 28
    • 0036020050 scopus 로고    scopus 로고
    • Receptor-mediated hepatocarcinogenesis: Role of hepatocyte proliferation and apoptosis
    • DOI 10.1034/j.1600-0773.2002.910101.x
    • J.D. Oliver, and R.A. Roberts Receptor-mediated hepatocarcinogenesis: role of hepatocyte proliferation and apoptosis Pharmacol. Toxicol. 91 2002 1 7 (Pubitemid 34753746)
    • (2002) Pharmacology and Toxicology , vol.91 , Issue.1 , pp. 1-7
    • Oliver, J.D.1    Roberts, R.A.2
  • 30
    • 0021316234 scopus 로고
    • Carcinoma of the prostate: The therapeutic dilemma
    • D.F. Paulson Carcinoma of the prostate: the therapeutic dilemma Annu. Rev. Med. 35 1984 341 372
    • (1984) Annu. Rev. Med. , vol.35 , pp. 341-372
    • Paulson, D.F.1
  • 31
    • 23144447140 scopus 로고    scopus 로고
    • CAR, the continuously advancing receptor, in drug metabolism and disease
    • DOI 10.2174/1389200054633899
    • M. Qatanani, and D.D. Moore CAR, the continuously advancing receptor, in drug metabolism and disease Curr. Drug Metab. 6 2005 329 339 (Pubitemid 41086766)
    • (2005) Current Drug Metabolism , vol.6 , Issue.4 , pp. 329-339
    • Qatanani, M.1    Moore, D.D.2
  • 33
    • 23344446651 scopus 로고    scopus 로고
    • Transcriptional networks in the liver: Hepatocyte nuclear factor 6 function is largely independent of Foxa2
    • DOI 10.1128/MCB.25.16.7069-7077.2005
    • N.E. Rubins, J.R. Friedman, P.P. Le, L. Zhang, J. Brestelli, and K.H. Kaestner Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2 Mol. Cell. Biol. 25 2005 7069 7077 (Pubitemid 41105905)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.16 , pp. 7069-7077
    • Rubins, N.E.1    Friedman, J.R.2    Le, P.P.3    Zhang, L.4    Brestelli, J.5    Kaestner, K.H.6
  • 34
    • 41349107158 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signalling molecules
    • F.G. Russel, J.B. Koenderink, and R. Masereeuw Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules Trends Pharmacol. Sci. 29 2008 200 207
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 200-207
    • Russel, F.G.1    Koenderink, J.B.2    Masereeuw, R.3
  • 35
    • 0035900778 scopus 로고    scopus 로고
    • Foxa3 (hepatocyte nuclear factor 3gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast
    • W. Shen, L.M. Scearce, J.E. Brestelli, N.J. Sund, and K.H. Kaestner Foxa3 (hepatocyte nuclear factor 3gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast J. Biol. Chem. 276 2001 42812 42817
    • (2001) J. Biol. Chem. , vol.276 , pp. 42812-42817
    • Shen, W.1    Scearce, L.M.2    Brestelli, J.E.3    Sund, N.J.4    Kaestner, K.H.5
  • 36
    • 0031960462 scopus 로고    scopus 로고
    • Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats
    • I. Shimizu, M. Yasuda, Y. Mizobuchi, Y.R. Ma, F. Liu, M. Shiba, T. Horie, and S. Ito Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats Gut 42 1998 112 119 (Pubitemid 28228398)
    • (1998) Gut , vol.42 , Issue.1 , pp. 112-119
    • Shimizu, I.1    Yasuda, M.2    Mizobuchi, Y.3    Ma, Y.-R.4    Liu, F.5    Shiba, M.6    Horie, T.7    Ito, S.8
  • 37
    • 0017664747 scopus 로고
    • Experimental models for the study of prostatic adenocarcinoma
    • J.K. Smolev, D.S. Coffey, and W.W. Scott Experimental models for the study of prostatic adenocarcinoma J. Urol. 118 1977 216 220
    • (1977) J. Urol. , vol.118 , pp. 216-220
    • Smolev, J.K.1    Coffey, D.S.2    Scott, W.W.3
  • 39
    • 0033921664 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 3β (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte
    • DOI 10.1128/MCB.20.14.5175-5183.2000
    • N.J. Sund, S.L. Ang, S.D. Sackett, W. Shen, N. Daigle, M.A. Magnuson, and K.H. Kaestner Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte Mol. Cell. Biol. 20 2000 5175 5183 (Pubitemid 30431570)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5175-5183
    • Sund, N.J.1    Ang, S.-L.2    Sackett, S.D.3    Shen, W.4    Daigle, N.5    Magnuson, M.A.6    Kaestner, K.H.7
  • 40
    • 75149117020 scopus 로고    scopus 로고
    • Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients
    • L.F. Thean, C. Loi, K.S. Ho, P.K. Koh, K.W. Eu, and P.Y. Cheah Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients Genes Chromosomes Cancer 49 2010 99 106
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 99-106
    • Thean, L.F.1    Loi, C.2    Ho, K.S.3    Koh, P.K.4    Eu, K.W.5    Cheah, P.Y.6
  • 43
  • 45
    • 77952990855 scopus 로고    scopus 로고
    • Androgen receptor promotes hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus RNA transcription
    • M.H. Wu, W.L. Ma, C.L. Hsu, Y.L. Chen, J.H. Ou, C.K. Ryan, Y.C. Hung, S. Yeh, and C. Chang Androgen receptor promotes hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus RNA transcription Sci. Transl. Med. 2 2010 32 35
    • (2010) Sci. Transl. Med. , vol.2 , pp. 32-35
    • Wu, M.H.1    Ma, W.L.2    Hsu, C.L.3    Chen, Y.L.4    Ou, J.H.5    Ryan, C.K.6    Hung, Y.C.7    Yeh, S.8    Chang, C.9
  • 47
    • 0025788510 scopus 로고
    • Roles of ovaries and testes in hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene
    • R. Yamamoto, H. Iishi, M. Tatsuta, M. Tsuji, and N. Terada Roles of ovaries and testes in hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene Int. J. Cancer 49 1991 83 88
    • (1991) Int. J. Cancer , vol.49 , pp. 83-88
    • Yamamoto, R.1    Iishi, H.2    Tatsuta, M.3    Tsuji, M.4    Terada, N.5
  • 49
    • 25144482864 scopus 로고    scopus 로고
    • Foxa2 integrates the transcriptional response of the hepatocyte to fasting
    • L. Zhang, N.E. Rubins, R.S. Ahima, L.E. Greenbaum, and K.H. Kaestner Foxa2 integrates the transcriptional response of the hepatocyte to fasting Cell Metab. 2 2005 141 148
    • (2005) Cell Metab. , vol.2 , pp. 141-148
    • Zhang, L.1    Rubins, N.E.2    Ahima, R.S.3    Greenbaum, L.E.4    Kaestner, K.H.5
  • 50
    • 0031983773 scopus 로고    scopus 로고
    • Does postmenopausal estrogen administration increase the risk of breast cancer? Contributions of animal, biochemical, and clinical investigative studies to a resolution of the controversy
    • B. Zumoff Does postmenopausal estrogen administration increase the risk of breast cancer? Contributions of animal, biochemical, and clinical investigative studies to a resolution of the controversy Proc. Soc. Exp. Biol. Med. 217 1998 30 37
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 30-37
    • Zumoff, B.1
  • 51
    • 58049204234 scopus 로고    scopus 로고
    • Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
    • Gao, N.; LeLay, J.; Vatamaniuk, M.Z.; Rieck, S.; Friedman, J.R.; Kaestner, K.H. (2008). Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 22, 3435-3448.
    • (2008) Genes Dev. , vol.22 , pp. 3435-3448
    • Gao, N.1    Lelay, J.2    Vatamaniuk, M.Z.3    Rieck, S.4    Friedman, J.R.5    Kaestner, K.H.6
  • 52
    • 64549114508 scopus 로고    scopus 로고
    • Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
    • Gao, N.; White, P.; Kaestner, K.H. (2009). Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev. Cell 16, 588-599.
    • (2009) Dev. Cell , vol.16 , pp. 588-599
    • Gao, N.1    White, P.2    Kaestner, K.H.3
  • 53
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S.; Benner, C.; Spann, N.; Bertolino, E.; Lin, Y.C.; Laslo, P.; Cheng, J.X.; Murre, C.; Singh, H.; Glass, C.K. (2011). Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589.
    • (2011) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6    Cheng, J.X.7    Murre, C.8    Singh, H.9    Glass, C.K.10
  • 56
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • DOI 10.1126/science.1140485
    • Naugler, W.E.; Sakurai, T.; Kim, S.; Maeda, S.; Kim, K.; Elsharkawy, A.M.; Karin, M. (2007). Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317, 121-124. (Pubitemid 47056470)
    • (2007) Science , vol.317 , Issue.5834 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3    Maeda, S.4    Kim, K.5    Elsharkawy, A.M.6    Karin, M.7
  • 57
    • 23344446651 scopus 로고    scopus 로고
    • Transcriptional networks in the liver: Hepatocyte nuclear factor 6 function is largely independent of Foxa2
    • DOI 10.1128/MCB.25.16.7069-7077.2005
    • Rubins, N.E.; Friedman, J.R.; Le, P.P.; Zhang, L.; Brestelli, J.; Kaestner, K.H. (2005). Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2. Mol. Cell. Biol. 25, 7069-7077. (Pubitemid 41105905)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.16 , pp. 7069-7077
    • Rubins, N.E.1    Friedman, J.R.2    Le, P.P.3    Zhang, L.4    Brestelli, J.5    Kaestner, K.H.6
  • 58
    • 0033921664 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 3β (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte
    • DOI 10.1128/MCB.20.14.5175-5183.2000
    • Sund, N.J.; Ang, S.L.; Sackett, S.D.; Shen, W.; Daigle, N.; Magnuson, M.A.; Kaestner, K.H. (2000). Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte. Mol. Cell. Biol. 20, 5175-5183. (Pubitemid 30431570)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5175-5183
    • Sund, N.J.1    Ang, S.-L.2    Sackett, S.D.3    Shen, W.4    Daigle, N.5    Magnuson, M.A.6    Kaestner, K.H.7


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