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Volumn 11, Issue , 2011, Pages

STAT3 activation in monocytes accelerates liver cancer progression

Author keywords

Inflammation; Liver cancer; Stat3

Indexed keywords

INTERLEUKIN 6; NSC 74859; PROTEIN INHIBITOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; AMINOSALICYLIC ACID DERIVATIVE; BENZENESULFONIC ACID DERIVATIVE; CARCINOGEN; DIETHYLNITROSAMINE; RNA 18S; STAT3 PROTEIN, HUMAN;

EID: 82655183784     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-506     Document Type: Article
Times cited : (70)

References (54)
  • 1
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 2
    • 79952996039 scopus 로고    scopus 로고
    • Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
    • Grivennikov SI, Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 2011, 70(Suppl 1):i104-i108.
    • (2011) Ann Rheum Dis , vol.70 , Issue.SUPPL. 1
    • Grivennikov, S.I.1    Karin, M.2
  • 4
    • 78650624793 scopus 로고    scopus 로고
    • Innate immune mechanisms of colitis and colitis-associated colorectal cancer
    • Saleh M, Trinchieri G. Innate immune mechanisms of colitis and colitis-associated colorectal cancer. Nat Rev 2011, 11(1):9-20.
    • (2011) Nat Rev , vol.11 , Issue.1 , pp. 9-20
    • Saleh, M.1    Trinchieri, G.2
  • 5
    • 84861186736 scopus 로고    scopus 로고
    • Jekyll and Hyde: the role of the microenvironment on the progression of cancer
    • Allen M, Louise Jones J. Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J Pathol 2011, 223(2):162-176.
    • (2011) J Pathol , vol.223 , Issue.2 , pp. 162-176
    • Allen, M.1    Louise Jones, J.2
  • 6
    • 77953485565 scopus 로고    scopus 로고
    • Molecular pathways linking inflammation and cancer
    • Mantovani A. Molecular pathways linking inflammation and cancer. Curr Mol Med 2010, 10(4):369-373.
    • (2010) Curr Mol Med , vol.10 , Issue.4 , pp. 369-373
    • Mantovani, A.1
  • 7
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: a leading role for STAT3
    • Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009, 9(11):798-809.
    • (2009) Nat Rev Cancer , vol.9 , Issue.11 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 9
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • Karin M. NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol 2009, 1(5):a000141.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , Issue.5
    • Karin, M.1
  • 10
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev 2007, 7(1):41-51.
    • (2007) Nat Rev , vol.7 , Issue.1 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 14
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterol 2007, 132(7):2557-2576.
    • (2007) Gastroenterol , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 15
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology (Baltimore, Md) 2008, 48(4):1312-1327.
    • (2008) Hepatology (Baltimore, Md) , vol.48 , Issue.4 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 17
    • 32944463507 scopus 로고    scopus 로고
    • Cytokines, STATs and liver disease
    • Gao B. Cytokines, STATs and liver disease. Cell Mol Immunol 2005, 2(2):92-100.
    • (2005) Cell Mol Immunol , vol.2 , Issue.2 , pp. 92-100
    • Gao, B.1
  • 18
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva S, Sun R, Pan HN, Hong F, Gao B. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatol 2004, 39(5):1332-1342.
    • (2004) Hepatol , vol.39 , Issue.5 , pp. 1332-1342
    • Radaeva, S.1    Sun, R.2    Pan, H.N.3    Hong, F.4    Gao, B.5
  • 23
    • 77956238512 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells
    • Liu Y, Li PK, Li C, Lin J. Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells. Biol Chem 2010, 285(35):27429-27439.
    • (2010) Biol Chem , vol.285 , Issue.35 , pp. 27429-27439
    • Liu, Y.1    Li, P.K.2    Li, C.3    Lin, J.4
  • 25
    • 65549129226 scopus 로고    scopus 로고
    • Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells
    • Xin H, Zhang C, Herrmann A, Du Y, Figlin R, Yu H. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer res 2009, 69(6):2506-2513.
    • (2009) Cancer res , vol.69 , Issue.6 , pp. 2506-2513
    • Xin, H.1    Zhang, C.2    Herrmann, A.3    Du, Y.4    Figlin, R.5    Yu, H.6
  • 26
    • 83855160973 scopus 로고    scopus 로고
    • Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report
    • Haftchenary S, Avadisian M, Gunning PT. Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report. Anti-cancer drugs 2010,
    • (2010) Anti-cancer drugs
    • Haftchenary, S.1    Avadisian, M.2    Gunning, P.T.3
  • 27
    • 83855164200 scopus 로고    scopus 로고
    • Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in hepatocellular carcinoma
    • WY W, ZS W, CL Z, XL M, PE L. Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in hepatocellular carcinoma. Exp Ther Med 2011,
    • (2011) Exp Ther Med
    • WY, W.1    ZS, W.2    CL, Z.3    XL, M.4    PE, L.5
  • 28
    • 0020603511 scopus 로고
    • Kinetics of diethylnitrosamine hepatocarcinogenesis in the infant mouse
    • Vesselinovitch SD, Mihailovich N. Kinetics of diethylnitrosamine hepatocarcinogenesis in the infant mouse. Cancer Res 1983, 43(9):4253-4259.
    • (1983) Cancer Res , vol.43 , Issue.9 , pp. 4253-4259
    • Vesselinovitch, S.D.1    Mihailovich, N.2
  • 29
    • 75149115740 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
    • Fan Y, Boivin GP, Knudsen ES, Nebert DW, Xia Y, Puga A. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res 2010, 70(1):212-220.
    • (2010) Cancer Res , vol.70 , Issue.1 , pp. 212-220
    • Fan, Y.1    Boivin, G.P.2    Knudsen, E.S.3    Nebert, D.W.4    Xia, Y.5    Puga, A.6
  • 30
    • 0036731485 scopus 로고    scopus 로고
    • Stats: transcriptional control and biological impact
    • Levy DE, Darnell JE. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002, 3(9):651-662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.9 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 32
    • 4944239032 scopus 로고    scopus 로고
    • Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
    • Chan KS, Sano S, Kiguchi K, Anders J, Komazawa N, Takeda J, DiGiovanni J. Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis. J Clin Invest 2004, 114(5):720-728.
    • (2004) J Clin Invest , vol.114 , Issue.5 , pp. 720-728
    • Chan, K.S.1    Sano, S.2    Kiguchi, K.3    Anders, J.4    Komazawa, N.5    Takeda, J.6    DiGiovanni, J.7
  • 33
    • 34250858888 scopus 로고    scopus 로고
    • Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma
    • Yang SF, Wang SN, Wu CF, Yeh YT, Chai CY, Chunag SC, Sheen MC, Lee KT. Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma. J Clin Pathol 2007, 60(6):642-648.
    • (2007) J Clin Pathol , vol.60 , Issue.6 , pp. 642-648
    • Yang, S.F.1    Wang, S.N.2    Wu, C.F.3    Yeh, Y.T.4    Chai, C.Y.5    Chunag, S.C.6    Sheen, M.C.7    Lee, K.T.8
  • 35
    • 77955702663 scopus 로고    scopus 로고
    • C-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair
    • Machida K, Tsukamoto H, Liu JC, Han YP, Govindarajan S, Lai MM, Akira S, Ou JH. c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair. Hepatology (Baltimore, Md) 2010, 52(2):480-492.
    • (2010) Hepatology (Baltimore, Md) , vol.52 , Issue.2 , pp. 480-492
    • Machida, K.1    Tsukamoto, H.2    Liu, J.C.3    Han, Y.P.4    Govindarajan, S.5    Lai, M.M.6    Akira, S.7    Ou, J.H.8
  • 36
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010, 140(2):197-208.
    • (2010) Cell , vol.140 , Issue.2 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3    He, G.4    Ali, S.R.5    Holzer, R.G.6    Osterreicher, C.H.7    Takahashi, H.8    Karin, M.9
  • 38
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009, 206(7):1457-1464.
    • (2009) J Exp Med , vol.206 , Issue.7 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 39
    • 24344465888 scopus 로고    scopus 로고
    • Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis
    • Starkel P, De Saeger C, Leclercq I, Strain A, Horsmans Y. Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis. J Hepatol 2005, 43(4):687-695.
    • (2005) J Hepatol , vol.43 , Issue.4 , pp. 687-695
    • Starkel, P.1    De Saeger, C.2    Leclercq, I.3    Strain, A.4    Horsmans, Y.5
  • 40
    • 33847241527 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 3 in liver fibrosis progression in chronic hepatitis C-infected patients
    • Starkel P, Saeger CD, Leclercq I, Horsmans Y. Role of signal transducer and activator of transcription 3 in liver fibrosis progression in chronic hepatitis C-infected patients. Lab Invest 2007, 87(2):173-181.
    • (2007) Lab Invest , vol.87 , Issue.2 , pp. 173-181
    • Starkel, P.1    Saeger, C.D.2    Leclercq, I.3    Horsmans, Y.4
  • 41
    • 78650934214 scopus 로고    scopus 로고
    • Cytokine disbalance in common human cancers
    • Culig Z. Cytokine disbalance in common human cancers. Biochimica et biophysica acta 2011, 1813(2):308-314.
    • (2011) Biochimica et biophysica acta , vol.1813 , Issue.2 , pp. 308-314
    • Culig, Z.1
  • 43
    • 7044229778 scopus 로고    scopus 로고
    • Primary liver cancer: worldwide incidence and trends
    • Bosch FX, Ribes J, Diaz M, Cleries R. Primary liver cancer: worldwide incidence and trends. Gastroenterol 2004, 127(5 Suppl 1):S5-S16.
    • (2004) Gastroenterol , vol.127 , Issue.5 SUPPL. 1
    • Bosch, F.X.1    Ribes, J.2    Diaz, M.3    Cleries, R.4
  • 52
    • 55849107422 scopus 로고    scopus 로고
    • Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice
    • Kujawski M, Kortylewski M, Lee H, Herrmann A, Kay H, Yu H. Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. J Clin Invest 2008, 118(10):3367-3377.
    • (2008) J Clin Invest , vol.118 , Issue.10 , pp. 3367-3377
    • Kujawski, M.1    Kortylewski, M.2    Lee, H.3    Herrmann, A.4    Kay, H.5    Yu, H.6
  • 54
    • 70749102261 scopus 로고    scopus 로고
    • Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production
    • e2121-e2122
    • Lafdil F, Wang H, Park O, Zhang W, Moritoki Y, Yin S, Fu XY, Gershwin ME, Lian ZX, Gao B. Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production. Gastroenterol 2009, 137(6):2125-2135. e2121-e2122.
    • (2009) Gastroenterol , vol.137 , Issue.6 , pp. 2125-2135
    • Lafdil, F.1    Wang, H.2    Park, O.3    Zhang, W.4    Moritoki, Y.5    Yin, S.6    Fu, X.Y.7    Gershwin, M.E.8    Lian, Z.X.9    Gao, B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.