DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation

Cancer Research

Volumn 70, Issue 15, 2010, Pages 6258-6267

  Wang, Hong ^a   Yang, Eddy S ^a   Jiang, Juhong ^a   Nowsheen, Somaira ^a   Xia, Fen ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CISPLATIN; DOUBLE STRANDED DNA;

ARTICLE; BREAST CANCER; CANCER CELL; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CLONOGENESIS; COLON CANCER; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IONIZING RADIATION; PRIORITY JOURNAL;

BRCA1 PROTEIN; BREAST NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; CELL NUCLEUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; FEMALE; HUMANS;

EID: 77955404832     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4713     Document Type: Article

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