BIN1 regulates BACE1 intracellular trafficking and amyloid-β production

Human Molecular Genetics

Volumn 25, Issue 14, 2016, Pages 2948-2958

  Miyagawa, Toji ^a,b   Ebinuma, Ihori ^a   Morohashi, Yuichi ^a   Hori, Yukiko ^a   Chang, Mee Young ^c   Hattori, Haruhiko ^d   Maehara, Tomoaki ^d   Yokoshima, Satoshi ^d   Fukuyama, Tohru ^d   Tsuji, Shoji ^b   Iwatsubo, Takeshi ^b   Prendergast, George C ^c   Tomita, Taisuke ^a  

^a Graduate School of Pharmaceutical Sciences   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE 1; BIN1 PROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BIN1 PROTEIN, HUMAN; NUCLEAR PROTEIN; SECRETASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENDOSOME; FEMALE; GENE FUNCTION; GENE TARGETING; HELA CELL LINE; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN SECRETION; PROTEIN SYNTHESIS; ALZHEIMER DISEASE; ANIMAL; BIOSYNTHESIS; BRAIN; ENDOCYTOSIS; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; NERVE CELL; PATHOLOGY; PROTEIN TRANSPORT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; ENDOCYTOSIS; ENDOSOMES; HUMANS; LYSOSOMES; MICE; MICE, KNOCKOUT; NEURONS; NUCLEAR PROTEINS; PROTEIN TRANSPORT; PROTEOLYSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 84988002075     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw146     Document Type: Article

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