Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

Molecular Psychiatry

Volumn 18, Issue 11, 2013, Pages 1225-1234

  Chapuis, J ^a   Hansmannel, F ^a   Gistelinck, M ^b   Mounier, A ^a   Van Cauwenberghe, C ^b,c   Kolen, K V ^d   Geller, F ^a   Sottejeau, Y ^a   Harold, D ^e   Dourlen, P ^a   Grenier Boley, B ^a   Kamatani, Y ^f   Delepine, B ^g   Demiautte, F ^a   Zelenika, D ^g   Zommer, N ^a   Hamdane, M ^a   Bellenguez, C ^a   Dartigues, J F ^h,i,j   Hauw, J J ^k   Letronne, F ^a   Ayral, A M ^a   Sleegers, K ^b,c   Schellens, A ^b   Broeck, L V ^b   Engelborghs, S ^c,l   De Deyn, P P ^c,l   Vandenberghe, R ^m   O'Donovan, M ^e   Owen, M ^e   Epelbaum, J ⁿ   Mercken, M ^d   Karran, E ^d   Bantscheff, M ^o   Drewes, G ^o   Joberty, G ^o   Campion, D ^p,q   Octave, J N ^r   Berr, C ^s   Lathrop, M ^f,g   Callaerts, P ^b   Mann, D ^t   Williams, J ^e   Buee L ^a   Dewachter, I ^r   Van Broeckhoven, C ^b,c   Amouyel, P ^a   Moechars, D ^d   Dermaut, B ^a,b   Lambert, J C ^a   more..

^a UNIV LILLE   (France)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d Jansens Research Foundation   (Belgium)

^e CARDIFF UNIVERSITY   (United Kingdom)

^f FONDATION JEAN DAUSSET CEPH   (France)

^g CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^h JEAN PIERRE AUBERT RESEARCH CENTER   (France)

ⁱ UNIVERSITÉ DE BORDEAUX   (France)

^j BORDEAUX UNIVERSITY HOSPITAL   (France)

^k PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^l Hospital Network Antwerp Middelheim and Hoge Beuken   (Belgium)

^m UNIVERSITY OF LEUVEN   (Belgium)

ⁿ INSERM   (France)

^o GLAXOSMITHKLINE   (United Kingdom)

^p CHS du Rouvray   (France)

^q Centre National de Référence Maladie d'Alzheimer du Sujet Jeune   (France)

^r Institute of Neuroscience   (Belgium)

^s Montpellier 1 University   (France)

^t UNIVERSITY OF MANCHESTER   (United Kingdom)

more..

Author keywords

Alzheimer; BIN1; Brain; Drosophila; Tau

Indexed keywords

TAU PROTEIN;

AGED; ALLELE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIN1 GENE; BRAIN; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALZHEIMER DISEASE; ANIMALS; BRAIN; CARRIER PROTEINS; CASE-CONTROL STUDIES; CELLS, CULTURED; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOPHENOTYPES; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; NERVE DEGENERATION; NUCLEAR PROTEINS; PLAQUE, AMYLOID; POLYMORPHISM, SINGLE NUCLEOTIDE; SYNAPTOSOMES; TAU PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84888306100     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2013.1     Document Type: Article

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