Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of app processing in neurons

Cell Reports

Volumn 6, Issue 1, 2014, Pages 24-31

  Ye, Xuan ^a   Cai, Qian ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; DYNEIN ADENOSINE TRIPHOSPHATASE; SNAPIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; EMBRYO; ENDOSOME; LYSOSOME; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; REGULATORY MECHANISM; RETROGRADE PROTEIN TRANSPORT; UPREGULATION;

MUS;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; DYNEINS; ENDOSOMES; GENE DELETION; LYSOSOMES; MICE; NEURONS; PROTEIN TRANSPORT; PROTEOLYSIS; VESICULAR TRANSPORT PROTEINS;

EID: 84892504040     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.12.008     Document Type: Article

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