Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 17, 1999, Pages 9689-9694

  Ge, Kai ^a   Duhadaway, James ^a,b   Du, Wei ^a,b   Herlyn, Meenhard ^a   Rodeck, Ulrich ^a,c   Prendergast, George C ^a,b  

^a WISTAR INSTITUTE   (United States)

^b DuPont Pharmaceuticals Company   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Malignant transformation; Myc; Oncogene; Programmed cell death

Indexed keywords

APOPTOSIS; ARTICLE; EXON; GENE SEQUENCE; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MELANOMA; ONCOGENE C MYC; PRIORITY JOURNAL; RNA SPLICING; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOVIRIDAE; ALTERNATIVE SPLICING; ANIMALS; APOPTOSIS; BLOTTING, NORTHERN; BRAIN; CARRIER PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; COS CELLS; EXONS; GENES, TUMOR SUPPRESSOR; HUMANS; MELANOMA; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MYC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033578314     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.17.9689     Document Type: Article

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