A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing

Nature Chemical Biology

Volumn 12, Issue 11, 2016, Pages 980-987

  Liu, Kaiwen Ivy ^a   Ramli, Muhammad Nadzim Bin ^a   Woo, Cheok Wei Ariel ^a   Wang, Yuanming ^a,b   Zhao, Tianyun ^a   Zhang, Xiujun ^a,b   Yim, Guo Rong Daniel ^a   Chong, Bao Yi ^a,c   Gowher, Ali ^a   Chua, Mervyn Zi Hao ^a,d   Jung, Jonathan ^a   Lee, Jia Hui Jane ^a   Tan, Meng How ^a,b  

^a GENOME INSTITUTE OF SINGAPORE   (Singapore)

^b Nanyang Technological University   (Singapore)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d DEPARTMENT OF ELECTRONICS AND COMPUTER ENGINEERING   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AFIMOXIFENE; AMINO ACID; BETA CATENIN; CASPASE 9; CRE RECOMBINASE; CRISPR ASSOCIATED PROTEIN; DOXYCYCLINE; ENDONUCLEASE; ESTROGEN RECEPTOR; FANCONI ANEMIA GROUP F PROTEIN; GENOMIC DNA; TAMOXIFEN; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR EMX1; VASCULOTROPIN A;

ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION PROCESS; CONTROLLED STUDY; CRISPR CAS SYSTEM; GENE LOCUS; GENETIC ANALYSIS; GENETIC ENGINEERING; GENOME; HORMONE BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECTS; GENE EDITING; GENETICS; HEK293 CELL LINE; PROCEDURES;

CRISPR-CAS SYSTEMS; GENE EDITING; HEK293 CELLS; HUMANS; TAMOXIFEN;

EID: 84987678200     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2179     Document Type: Article

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