Nutrition and lifestyle in healthy aging: The telomerase challenge

Aging

Volumn 8, Issue 1, 2016, Pages 12-15

  Boccardi, Virginia ^a   Paolisso, Giuseppe ^b   Mecocci, Patrizia ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Elderly; Longevity; Nutrition; Telomerase; Telomere

Indexed keywords

TELOMERASE;

AGE; AGING; ANIMAL; CELL AGING; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HUMAN; LIFESTYLE; METABOLISM; NUTRITIONAL STATUS; RISK REDUCTION; STEM CELL; TELOMERE; TELOMERE HOMEOSTASIS;

AGE FACTORS; AGING; ANIMALS; CELL AGING; CELL PROLIFERATION; ENZYME ACTIVATION; HUMANS; LIFE STYLE; NUTRITIONAL STATUS; RISK REDUCTION BEHAVIOR; STEM CELLS; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 84986576831     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100886     Document Type: Article

References (70)

1. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013; 153:1194-1217.
2. Bowling A, Dieppe P. What is successful ageing and who should define it? BMJ. 2005; 331:1548-1551.
3. 7. Defining successful aging: a tangible or elusive concept? Gerontologist. 2015; 55:14-25.
4. Sharpless NE, DePinho RA. How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol. 2007; 8:703-713.
5. Sebastiani P, Perls TT. The genetics of extreme longevity: lessons from the new England centenarian study. Front Genet. 2012; 3:277.
6. Herskind AM., Mcgue M., Holm NV, Sorensen TI, Harvald B, Vaupel JW. The heritability of human longevity: a populationbased study of 2872 Danish twin pairs born 1870-1900. Hum. Genet. 1996; 97:319-32310.1007/BF02185763.
7. Kiefte-de Jong JC, Mathers JC, Franco OH. Nutrition and healthy ageing: the key ingredients. Proc Nutr Soc. 2014; 73:249-259.
8. Vasto S, Barera A, Rizzo C, Di Carlo M, Caruso C, Panotopoulos G Mediterranean diet and longevity: an example of nutraceuticals? Curr Vasc Pharmacol. 2014; 12:735-738.
9. Hausman DB, Fischer JG, Johnson MA Nutrition in centenarians. Maturitas. 2011; 68:203-209.
10. Cannella C, Savina C, Donini LM. Nutrition, longevity and behavior. Arch Gerontol Geriatr. 2009; 49:19-27.
11. Bengmark S. Impact of nutrition on ageing and disease. Curr Opin Clin Nutr Metab Care. 2006; 9:2-7.
12. Paul L. Diet, nutrition and telomere length. J Nutr Biochem. 2011; 22:895-901.
13. Lee JY, Jun NR, Yoon D, Shin C, Baik I. Association between dietary patterns in the remote past and telomere length. Eur J Clin Nutr. 2015; 69:1048-1052.
14. Sun Q, Shi L, Prescott J, Chiuve SE, Hu FB, De Vivo I, Stampfer MJ, Franks PW, Manson JE, Rexrode KM. Healthy lifestyle and leukocyte telomere length in U.S. women. PLoS One. 2012; 7:e38374.
15. Cassidy A, De Vivo I, Liu Y, Han J, Prescott J, Hunter DJ, Rimm EB. Associations between diet, lifestyle factors, and telomere length in women. Am J Clin Nutr. 2010; 91:1273-1280.
16. Sfeir AJ, Chai W, Shay JW, Wright WE. Telomere end processing: the terminal nucleotides of human chromosomes. Mol. Cell. 2005; 18:131-138.
17. de Lange T. Protection of mammalian telomeres Oncogene 2002; 21:532-540.
18. Baird DM, Kipling D. The extent and significance of telomere loss with age. Ann NY Acad Sci 2004; 1019:265-268.
19. Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 2007; 8: 729-740.
20. Tacutu R, Budovsky A, Yanai H, Fraifeld VE. Molecular links between cellular senescence, longevity and age related diseases-a systems biology perspective. Aging (Albany NY) 2011; 3:1178-1191.
21. Hayflick L. The cell biology of human aging. The New England Journal of Medicine 1976; 295:1302-1308.
22. Blackburn EH. Telomere states and cell fates. Nature 2000; 408:53-56.
23. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106:661-673.
24. Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, Adams RR, Chang, E, Allsopp RC, Yu J, Le S, West MD, Harley CB, Andrews WH, Greider CW, Villeponteau B. The RNA component of human telomerase. Science 1995; 269:1236-1241.
25. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW. Telomerase activity in human germline and embryonic tissues and cells. Dev. Genet. 1996; 18:173-179.
26. Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur. J. Cancer 1997; 33:787-791.
27. Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC. Telomerase maintains telomere structure in normal human cells. Cell 2003; 114:241-253.
28. Sanders JL, Newman AB. Telomere Length in Epidemiology: A Biomarker of Aging, Age-Related Disease, Both, or Neither? Epidemiol Rev 2013; 35:112-131.
29. Simons MJ. Questioning causal involvement of telomeres in aging. Ageing Res Rev 2015; pii: S1568-1637 30015-5.
30. Vera E, Bernardes de Jesus B, Foronda M, Flores JM, Blasco MA. The rate of increase of short telomeres predicts longevity in mammals. Cell Rep. 2012; 2:732-737.
31. Calado RT, Dumitriu B. Telomere dynamics in mice and humans. Semin Hematol. 2013; 50:165-174.
32. Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH. Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology 2006; 31:277-287.
33. Panossian LA, Porter VR, Valenzuela HF, Zhu X, Reback E, Masterman D, Cummings JL, Effros RB. Telomere shortening in T cells correlates with Alzheimer's disease status. Neurobiol Aging 2003; 4:77-84.
34. Honig LS, Schupf N, Lee JH, Tang MX, Mayeux R. Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia. Ann Neurol 2006; 60:181-187.
35. Thomas P, O' Callaghan NJ, Fenech M. Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech Ageing Dev 2008; 129:183-190.
36. Hochstrasser T, Marksteiner J, Humpel C. Telomere length is age-dependent and reduced in monocytes of Alzheimer patients. Exp. Gerontol. 2012; 47:160-163.
37. Cai Z, Yan LJ, Ratka A. Telomere shortening and Alzheimer's disease. Neuromolecular Med. 2013; 15:25-48.
38. Boccardi V, Pelini L, Ercolani S, Ruggiero C, Mecocci P. From cellular senescence to Alzheimer's disease: The role of telomere shortening. Ageing Res Rev. 2015; 22: 1-8.
39. Saretzki G. Extra-telomeric functions of human telomerase: cancer, mitochondria and oxidative stress. Curr Pharm Des. 2014; 20:6386-6403.
40. Martínez P, Blasco MA. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nat Rev Cancer. 2011; 11:161-176.
41. Saretzki G. Telomerase, mitochondria and oxidative stress. Exp Gerontol. 2009; 44:485-492.
42. Mundstock E, Sarria EE, Zatti H, Mattos Louzada F, Kich Grun L, Herbert Jones M, Guma FT, Mazzola In Memoriam J, Epifanio M, Stein RT, Barbé-Tuana FM, Mattiello R. Effect of obesity on telomere length: Systematic review and meta-analysis. Obesity (Silver Spring). 2015. doi: 10.1002/oby.21183
43. Strazhesko I, Tkacheva O, Boytsov S, Akasheva D, Dudinskaya E, Vygodin V, Skvortsov D, Nilsson P Association of Insulin Resistance, Arterial Stiffness and Telomere Length in Adults Free of Cardiovascular Diseases. PLoS One. 2015; 10:e0136676.
44. Demissie S, Levy D, Benjamin EJ, Cupples LA, Gardner JP, Herbert A, et al. Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell. 2006; 5:325-330.
45. Haycock PC, Heydon EE, Kaptoge S, Butterworth AS, Thompson A, Willeit P. Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis. BMJ. 2014; 349:g4227.
46. Zietzer A, Hillmeister P Leucocyte telomere length as marker for cardiovascular ageing. Acta Physiol (Oxf). 2014; 211:251-256.
47. Barrett JH, Iles MM, Dunning AM, Pooley KA. Telomere length and common disease: study design and analytical challenges. Hum Genet. 2015; 134:679-689.
48. Cherkas LF, Hunkin JL, Kato BS, Richards JB, Gardner JP, Surdulescu GL, Kimura M, Lu X, Spector TD, Aviv A. The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med. 2008; 168:154-158.
49. Cassidy A, De Vivo I, Liu Y, Han J, Prescott J, Hunter DJ, Rimm EB. Associations between diet, lifestyle factors, and telomere length in women. Am J Clin Nutr. 2010; 91:1273-1280.
50. Mirabello L, Huang WY, Wong JY, Chatterjee N, Reding D, Crawford ED, De Vivo I, Hayes RB, Savage SA. The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging Cell. 2009; 8:405-413.
51. Strandberg TE, Saijonmaa O, Tilvis RS, Pitkälä KH, Strandberg AY, Miettinen TA, Fyhrquist F. Association of telomere length in older men with mortality and midlife body mass index and smoking. J Gerontol A Biol Sci Med Sci. 2011; 66:815-820.
52. LaRocca TJ, Seals DR, Pierce GL. Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity. Mech Ageing Dev. 2010; 131:165-167.
53. Chen W, Kimura M, Kim S, Cao X, Srinivasan SR, Berenson GS, Kark JD, Aviv A. Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule. J Gerontol A Biol Sci Med Sci. 2011; 66:312-319.
54. Ornish D, Lin J, Chan JM, Epel E, Kemp C, Weidner G, Marlin R, Frenda SJ, Magbanua MJ, Daubenmier J, Estay I, Hills NK, Chainani-Wu N, Carroll PR, Blackburn EH. Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. Lancet Oncol. 2013; 14:1112-1120.
55. Boccardi V, Esposito A, Rizzo MR, Marfella R, Barbieri M, Paolisso G. Mediterranean diet, telomere maintenance and health status among elderly. PLoS One. 2013; 8:e62781.
56. Fenech M. Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity. Mutat Res. 2012; 733:21-33.
57. Moores CJ, Fenech M, O'Callaghan NJ Telomere dynamics: the influence of folate and DNA methylation. Ann N Y Acad Sci. 2011; 1229:76-88.
58. Sen A, Marsche G, Freudenberger P, Schallert M, Toeglhofer AM, Nagl C, Schmidt R, Launer LJ, Schmidt H. Association between higher plasma lutein, zeaxanthin, and vitamin C concentrations and longer telomere length: results of the Austrian Stroke Prevention Study. J Am Geriatr Soc. 2014; 62:222-229.
59. Sharif R, Thomas P, Zalewski P, Fenech M The role of zinc in genomic stability. Mutat Res. 2012; 733:111-121.
60. Jayasena T, Poljak A, Smythe G, Braidy N, Münch G, Sachdev P. The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease.Ageing Res Rev. 2013; 12:867-883.
61. Thomas P, Wang YJ, Zhong JH, Kosaraju S, O'Callaghan NJ, Zhou XF, Fenech M. Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease. Mutat Res. 2009; 661:25-34.
62. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging.Science. 1996; 273:59-63.
63. Assmann KE, Lassale C, Andreeva VA, Jeandel C, Hercberg S, Galan P, Kesse-Guyot E. A Healthy Dietary Pattern at Midlife, Combined with a Regulated Energy Intake, Is Related to Increased Odds for Healthy Aging. J Nutr. 2015; 145:2139-2145.
64. de Cabo R, Carmona-Gutierrez D, Bernier M, Hall MN, Madeo F. The search for antiaging interventions: from elixirs to fasting regimens. Cell. 2014; 157:1515-1526.
65. Dernini S, Berry EM.Mediterranean Diet: From a Healthy Diet to a Sustainable Dietary Pattern. Front Nutr. 2015; 2:15.
66. Pérez-López FR, Chedraui P, Haya J, Cuadros JL. Effects of the Mediterranean diet on longevity and age-related morbid conditions. Maturitas. 2009; 64:67-79.
67. Roman B, Carta L, Martínez-González MA, Serra-Majem L. Effectiveness of the Mediterranean diet in the elderly. Clin Interv Aging. 2008; 3:97-109.
68. Ross SM. The traditional Mediterranean diet: an ancient prescription for health and longevity. Holist Nurs Pract. 2015; 29:174-177.
69. Mathers JC. Impact of nutrition on the ageing process. Br J Nutr. 2015; 113 Suppl:S18-22.
70. Gupta C, Prakash D. Nutraceuticals for geriatrics. J Tradit Complement Med. 2014; 5:5-14.