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Volumn 661, Issue 1-2, 2009, Pages 25-34

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease

Author keywords

Alzheimer's disease; Buccal; DNA damage; Micronuclei; Polyphenol

Indexed keywords

CATECHIN; CURCUMIN; EPICATECHIN; GALLIC ACID; GRAPE SEED EXTRACT; POLYPHENOL; PRESENILIN 1; PROANTHOCYANIDIN;

EID: 58849109761     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2008.10.016     Document Type: Article
Times cited : (85)

References (66)
  • 2
    • 0037405248 scopus 로고    scopus 로고
    • Oxidative stress in cultured cerebral endothelial cells induces chromosomal aberrations, micronuclei, and apoptosis
    • Bresgen N., Karlhuber G., Krizbai I., Bauer H., Bauer H.C., and Eckl P.M. Oxidative stress in cultured cerebral endothelial cells induces chromosomal aberrations, micronuclei, and apoptosis. J. Neurosci. Res. 72 (2003) 327-333
    • (2003) J. Neurosci. Res. , vol.72 , pp. 327-333
    • Bresgen, N.1    Karlhuber, G.2    Krizbai, I.3    Bauer, H.4    Bauer, H.C.5    Eckl, P.M.6
  • 4
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Abeta 42 Fibrils
    • Gotz J., Chen F., van Dorpe J., and Nitsch R.M. Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Abeta 42 Fibrils. Science 293 (2001) 1491-1495
    • (2001) Science , vol.293 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    van Dorpe, J.3    Nitsch, R.M.4
  • 5
    • 0034573291 scopus 로고    scopus 로고
    • Piecing together Alzheimer's
    • St. George-Hyslop P.H. Piecing together Alzheimer's. Sci. Am. 283 (2000) 76-83
    • (2000) Sci. Am. , vol.283 , pp. 76-83
    • St. George-Hyslop, P.H.1
  • 7
    • 0033954991 scopus 로고    scopus 로고
    • Oxidative stress and Alzheimer disease
    • Christen Y. Oxidative stress and Alzheimer disease. Am. J. Clin. Nutr. 71 (2000) 621S-629S
    • (2000) Am. J. Clin. Nutr. , vol.71
    • Christen, Y.1
  • 8
    • 0036860349 scopus 로고    scopus 로고
    • Metal complexing agents as therapies for Alzheimer's disease
    • Bush A.I. Metal complexing agents as therapies for Alzheimer's disease. Neurobiol. Aging (2002) 1031-1038
    • (2002) Neurobiol. Aging , pp. 1031-1038
    • Bush, A.I.1
  • 9
    • 0037386086 scopus 로고    scopus 로고
    • The metallobiology of Alzheimer's disease
    • Bush A.I. The metallobiology of Alzheimer's disease. Trends Neurosci. 26 (2003) 207-214
    • (2003) Trends Neurosci. , vol.26 , pp. 207-214
    • Bush, A.I.1
  • 11
    • 36049051628 scopus 로고    scopus 로고
    • Buccal micronucleus cytome biomarkers may be associated with Alzheimer's disease
    • Thomas P., Hecker J., Faunt J., and Fenech M. Buccal micronucleus cytome biomarkers may be associated with Alzheimer's disease. Mutagenesis 22 (2007) 371-379
    • (2007) Mutagenesis , vol.22 , pp. 371-379
    • Thomas, P.1    Hecker, J.2    Faunt, J.3    Fenech, M.4
  • 13
    • 13644256048 scopus 로고    scopus 로고
    • Beal oxidative damage as an early marker of Alzheimer's disease and mild cognitive impairment
    • Flint M. Beal oxidative damage as an early marker of Alzheimer's disease and mild cognitive impairment. Neurobiol. Ageing 26 (2005) 585-586
    • (2005) Neurobiol. Ageing , vol.26 , pp. 585-586
    • Flint, M.1
  • 14
    • 39749173730 scopus 로고    scopus 로고
    • Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease
    • Thomas P., O'Callaghan N.J., and Fenech M. Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech. Ageing Dev. 129 (2008) 183-190
    • (2008) Mech. Ageing Dev. , vol.129 , pp. 183-190
    • Thomas, P.1    O'Callaghan, N.J.2    Fenech, M.3
  • 15
    • 0033942779 scopus 로고    scopus 로고
    • Zglinicki role of oxidative stress in telomere length regulation and replicative senescence
    • Von T. Zglinicki role of oxidative stress in telomere length regulation and replicative senescence. Ann. N.Y. Acad. Sci. 908 (2000) 99-110
    • (2000) Ann. N.Y. Acad. Sci. , vol.908 , pp. 99-110
    • Von, T.1
  • 16
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim G.P., Chu T., Yang F., Beech W., Frautschy S.A., and Cole G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21 (2001) 8370-8377
    • (2001) J. Neurosci. , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 17
    • 0033568849 scopus 로고    scopus 로고
    • Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
    • Joseph J.A., Shukitt-Hale B., Denisova N.A., Bielinski D., Martin A., McEwen J.J., and Bickford P.C. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J. Neurosci. 19 (1999) 8114-8121
    • (1999) J. Neurosci. , vol.19 , pp. 8114-8121
    • Joseph, J.A.1    Shukitt-Hale, B.2    Denisova, N.A.3    Bielinski, D.4    Martin, A.5    McEwen, J.J.6    Bickford, P.C.7
  • 19
    • 13244289773 scopus 로고    scopus 로고
    • Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity
    • Biswas S.K., McClure D., Jimenez L.A., Megson I.L., and Rahman I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid. Redox Signal. 7 (2005) 32-41
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 32-41
    • Biswas, S.K.1    McClure, D.2    Jimenez, L.A.3    Megson, I.L.4    Rahman, I.5
  • 23
    • 0031703638 scopus 로고    scopus 로고
    • An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect®
    • Nuttall S.L., Kendall M.J., Bombardelli E., and Morazzoni P. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect®. J. Clin. Pharm. Ther. 23 (1998) 385-389
    • (1998) J. Clin. Pharm. Ther. , vol.23 , pp. 385-389
    • Nuttall, S.L.1    Kendall, M.J.2    Bombardelli, E.3    Morazzoni, P.4
  • 24
    • 20744439570 scopus 로고    scopus 로고
    • Grape seed extract suppresses lipid peroxidation and reduces hypoxic ischemic brain injury in neonatal rats
    • Feng Y., Liu Y.M., Fratkins J.D., and LeBlanc M.H. Grape seed extract suppresses lipid peroxidation and reduces hypoxic ischemic brain injury in neonatal rats. Brain Res. Bull. 66 (2005) 120-127
    • (2005) Brain Res. Bull. , vol.66 , pp. 120-127
    • Feng, Y.1    Liu, Y.M.2    Fratkins, J.D.3    LeBlanc, M.H.4
  • 25
    • 31744438823 scopus 로고    scopus 로고
    • Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats
    • Balu M., Sangeetha P., Murali G., and Panneerselva C. Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats. Brain Res. Bull. 68 (2006) 469-473
    • (2006) Brain Res. Bull. , vol.68 , pp. 469-473
    • Balu, M.1    Sangeetha, P.2    Murali, G.3    Panneerselva, C.4
  • 26
    • 16644390607 scopus 로고    scopus 로고
    • Grape seed extract prevents H(2)O(2)-induced chromosomal damage in human lymphoblastoid cells
    • Sugisawa A., Inoue S., and Umegaki K. Grape seed extract prevents H(2)O(2)-induced chromosomal damage in human lymphoblastoid cells. Biol. Pharm. Bull. 27 (2004) 1459-1461
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 1459-1461
    • Sugisawa, A.1    Inoue, S.2    Umegaki, K.3
  • 27
    • 1642559404 scopus 로고    scopus 로고
    • Polyphenolics in grape seeds-biochemistry and functionality
    • Shi J., Yu J., Pohorly J.E., and Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J. Med. Food 6 (2003) 291-299
    • (2003) J. Med. Food , vol.6 , pp. 291-299
    • Shi, J.1    Yu, J.2    Pohorly, J.E.3    Kakuda, Y.4
  • 28
    • 15044340251 scopus 로고    scopus 로고
    • Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death
    • Li M.H., Jang J.H., Sun B., and Surh Y.J. Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death. Ann. N. Y. Acad. Sci. 1030 (2004) 317-329
    • (2004) Ann. N. Y. Acad. Sci. , vol.1030 , pp. 317-329
    • Li, M.H.1    Jang, J.H.2    Sun, B.3    Surh, Y.J.4
  • 34
    • 58849137668 scopus 로고    scopus 로고
    • J. laboratory http://jaxmice.jax.org/strain/004462.html (Technical support).
    • J. laboratory http://jaxmice.jax.org/strain/004462.html (Technical support).
  • 35
    • 3142734335 scopus 로고    scopus 로고
    • Polyphenol screening of pomace from red and white grape varieties (Vitis vinifera L.) by HPLC-DAD-MS/MS
    • Kammerer D., Claus A., Carle R., and Schieber A. Polyphenol screening of pomace from red and white grape varieties (Vitis vinifera L.) by HPLC-DAD-MS/MS. J. Agric. Food Chem. 52 (2004) 4360-4367
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 4360-4367
    • Kammerer, D.1    Claus, A.2    Carle, R.3    Schieber, A.4
  • 36
    • 0030912476 scopus 로고    scopus 로고
    • Components of the AIN-93 Diets as Improvements in the AIN-76A Diet
    • Reeves P.G. Components of the AIN-93 Diets as Improvements in the AIN-76A Diet. J. Nutr. 127 (1997) 838S
    • (1997) J. Nutr. , vol.127
    • Reeves, P.G.1
  • 37
    • 0036888160 scopus 로고    scopus 로고
    • Subchronic 3-month oral toxicity study of grape seed and grape skin extracts
    • Bentivegna S.S., and Whitney K.M. Subchronic 3-month oral toxicity study of grape seed and grape skin extracts. Food Chem. Toxicol. 40 (2002) 1731-1743
    • (2002) Food Chem. Toxicol. , vol.40 , pp. 1731-1743
    • Bentivegna, S.S.1    Whitney, K.M.2
  • 38
    • 38049042877 scopus 로고    scopus 로고
    • The buccal cytome and micronucleus frequency is substantially altered in Down's syndrome and normal ageing compared to young healthy controls
    • Thomas P., Harvey S., Gruner T., and Fenech M. The buccal cytome and micronucleus frequency is substantially altered in Down's syndrome and normal ageing compared to young healthy controls. Mutat. Res. 638 (2007) 37-47
    • (2007) Mutat. Res. , vol.638 , pp. 37-47
    • Thomas, P.1    Harvey, S.2    Gruner, T.3    Fenech, M.4
  • 41
    • 0034115582 scopus 로고    scopus 로고
    • Antioxidant activity and radioprotective effects against chromosomal damage induced in vivo by X-rays of flavan-3-ols (Procyanidins) from grape seeds (Vitis vinifera): comparative study versus other phenolic and organic compounds
    • Castillo J., Benavente-Garcia O., Lorente J., Alcaraz M., Redondo A., Ortuno A., and Del Rio J.A. Antioxidant activity and radioprotective effects against chromosomal damage induced in vivo by X-rays of flavan-3-ols (Procyanidins) from grape seeds (Vitis vinifera): comparative study versus other phenolic and organic compounds. J. Agric. Food Chem. 48 (2000) 1738-1745
    • (2000) J. Agric. Food Chem. , vol.48 , pp. 1738-1745
    • Castillo, J.1    Benavente-Garcia, O.2    Lorente, J.3    Alcaraz, M.4    Redondo, A.5    Ortuno, A.6    Del Rio, J.A.7
  • 42
    • 33751182576 scopus 로고    scopus 로고
    • Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes
    • Srinivasan M., Rajendra Prasad N., and Menon V.P. Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes. Mutat. Res. 611 (2006) 96-103
    • (2006) Mutat. Res. , vol.611 , pp. 96-103
    • Srinivasan, M.1    Rajendra Prasad, N.2    Menon, V.P.3
  • 44
    • 0033387397 scopus 로고    scopus 로고
    • beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease
    • Kovacs T., Cairns N.J., and Lantos P.L. beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease. Neuropathol. Appl. Neurobiol. 25 (1999) 481-491
    • (1999) Neuropathol. Appl. Neurobiol. , vol.25 , pp. 481-491
    • Kovacs, T.1    Cairns, N.J.2    Lantos, P.L.3
  • 45
    • 0031875445 scopus 로고    scopus 로고
    • Presenilin-1 mRNA and beta-amyloid precursor protein mRNA are expressed in the developing rat olfactory and vestibulocochlear systems
    • Utsumi M., Sato K., Tanimukai H., Kudo T., Nishimura M., Takeda M., and Tohyama M. Presenilin-1 mRNA and beta-amyloid precursor protein mRNA are expressed in the developing rat olfactory and vestibulocochlear systems. Acta Otolaryngol. 118 (1998) 549-553
    • (1998) Acta Otolaryngol. , vol.118 , pp. 549-553
    • Utsumi, M.1    Sato, K.2    Tanimukai, H.3    Kudo, T.4    Nishimura, M.5    Takeda, M.6    Tohyama, M.7
  • 47
    • 4043119110 scopus 로고    scopus 로고
    • Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes
    • Calabrese V., Boyd-Kimball D., Scapagnini G., and Butterfield D.A. Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes. In Vivo 18 (2004) 245-267
    • (2004) In Vivo , vol.18 , pp. 245-267
    • Calabrese, V.1    Boyd-Kimball, D.2    Scapagnini, G.3    Butterfield, D.A.4
  • 48
    • 0036212575 scopus 로고    scopus 로고
    • Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance
    • Calabrese V., Scapagnini G., Ravagna A., Fariello R.G., Giuffrida Stella A.M., and Abraham N.G. Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance. J. Neurosci. Res. 68 (2002) 65-75
    • (2002) J. Neurosci. Res. , vol.68 , pp. 65-75
    • Calabrese, V.1    Scapagnini, G.2    Ravagna, A.3    Fariello, R.G.4    Giuffrida Stella, A.M.5    Abraham, N.G.6
  • 49
    • 0030886054 scopus 로고    scopus 로고
    • Reduced stress defense in heme oxygenase 1-deficient cells
    • Poss K.D., and Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 10925-10930
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10925-10930
    • Poss, K.D.1    Tonegawa, S.2
  • 51
    • 15444372049 scopus 로고    scopus 로고
    • Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro
    • Ono K., Hasegawa K., Naiki H., and Yamada M. Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro. Biochem. Biophys. Res. Commun. 330 (2005) 111-116
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 111-116
    • Ono, K.1    Hasegawa, K.2    Naiki, H.3    Yamada, M.4
  • 52
    • 4644275696 scopus 로고    scopus 로고
    • Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models
    • (discussion 369-443)
    • Baum L., and Ng A. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J. Alzheimer's Dis. 6 (2004) 367-377 (discussion 369-443)
    • (2004) J. Alzheimer's Dis. , vol.6 , pp. 367-377
    • Baum, L.1    Ng, A.2
  • 53
    • 3843144969 scopus 로고    scopus 로고
    • Health aspects of functional grape seed constituents
    • Yilmaz Y., and Toledo R.T. Health aspects of functional grape seed constituents. Trends Food Sci. Technol. 15 (2004) 422-433
    • (2004) Trends Food Sci. Technol. , vol.15 , pp. 422-433
    • Yilmaz, Y.1    Toledo, R.T.2
  • 55
    • 0029935490 scopus 로고    scopus 로고
    • Free radical scavenging activity of curcuminoids
    • Sreejayan N., and Rao M.N. Free radical scavenging activity of curcuminoids. Arzneimittelforschung 46 (1996) 169-171
    • (1996) Arzneimittelforschung , vol.46 , pp. 169-171
    • Sreejayan, N.1    Rao, M.N.2
  • 56
    • 0031033145 scopus 로고    scopus 로고
    • Nitric oxide scavenging by curcuminoids
    • Sreejayan, and Rao M.N. Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 49 (1997) 105-107
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 105-107
    • Sreejayan1    Rao, M.N.2
  • 57
    • 0034901418 scopus 로고    scopus 로고
    • Radioprotective effects against chromosomal damage induced in human lymphocytes by gamma-rays as a function of polymerization grade of grape seed extracts
    • Castillo J., Benavente-Garcia O., Del Bano M.J., Lorente J., Alcaraz M., and Dato M.J. Radioprotective effects against chromosomal damage induced in human lymphocytes by gamma-rays as a function of polymerization grade of grape seed extracts. J. Med. Food 4 (2001) 117-123
    • (2001) J. Med. Food , vol.4 , pp. 117-123
    • Castillo, J.1    Benavente-Garcia, O.2    Del Bano, M.J.3    Lorente, J.4    Alcaraz, M.5    Dato, M.J.6
  • 59
    • 0028278766 scopus 로고
    • Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver
    • Reddy A.C., and Lokesh B.R. Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver. Food Chem. Toxicol. 32 (1994) 279-283
    • (1994) Food Chem. Toxicol. , vol.32 , pp. 279-283
    • Reddy, A.C.1    Lokesh, B.R.2
  • 60
    • 20444369178 scopus 로고    scopus 로고
    • Rejuvenation of antioxidant system in central nervous system of aged rats by grape seed extract
    • Balu M., Sangeetha P., Haripriya D., and Panneerselvam C. Rejuvenation of antioxidant system in central nervous system of aged rats by grape seed extract. Neurosci. Lett. 383 (2005) 295-300
    • (2005) Neurosci. Lett. , vol.383 , pp. 295-300
    • Balu, M.1    Sangeetha, P.2    Haripriya, D.3    Panneerselvam, C.4
  • 61
    • 0034190372 scopus 로고    scopus 로고
    • Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches
    • Rahman I., and MacNee W. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic. Biol. Med. 28 (2000) 1405-1420
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1405-1420
    • Rahman, I.1    MacNee, W.2
  • 62
    • 0033806242 scopus 로고    scopus 로고
    • Oxidative stress and regulation of glutathione in lung inflammation
    • Rahman I., and MacNee W. Oxidative stress and regulation of glutathione in lung inflammation. Eur. Respir. J. 16 (2000) 534-554
    • (2000) Eur. Respir. J. , vol.16 , pp. 534-554
    • Rahman, I.1    MacNee, W.2
  • 63
    • 0036489186 scopus 로고    scopus 로고
    • Flavonoids increase the intracellular glutathione level by transactivation of the [gamma]-glutamylcysteine synthetase catalytical subunit promoter
    • Myhrstad M.C.W., Carlsen H., Nordstrom O., Blomhoff R., and Moskaug J.O. Flavonoids increase the intracellular glutathione level by transactivation of the [gamma]-glutamylcysteine synthetase catalytical subunit promoter. Free Radic. Biol. Med. 32 (2002) 386-393
    • (2002) Free Radic. Biol. Med. , vol.32 , pp. 386-393
    • Myhrstad, M.C.W.1    Carlsen, H.2    Nordstrom, O.3    Blomhoff, R.4    Moskaug, J.O.5
  • 64
    • 0034862568 scopus 로고    scopus 로고
    • Age-related changes in wound healing
    • Thomas D.R. Age-related changes in wound healing. Drugs Aging 18 (2001) 607-620
    • (2001) Drugs Aging , vol.18 , pp. 607-620
    • Thomas, D.R.1
  • 66
    • 0037077393 scopus 로고    scopus 로고
    • Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats
    • Yamakoshi J., Saito M., Kataoka S., and Tokutake S. Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats. J. Agric. Food Chem. 50 (2002) 4983-4988
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 4983-4988
    • Yamakoshi, J.1    Saito, M.2    Kataoka, S.3    Tokutake, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.