Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease

Journal of Alzheimer's Disease

Volumn 54, Issue 2, 2016, Pages 669-678

  Beckelman, Brenna C ^a   Day, Stephen ^a   Zhou, Xueyan ^a   Donohue, Maggie ^b   Gouras, Gunnar K ^c   Klann, Eric ^b   Keene, C Dirk ^d   Ma, Tao ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; elongation factor; long term potentiation; mTOR; protein synthesis; synaptic plasticity

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BRAIN PROTEIN; ELONGATION FACTOR 1ALPHA; FORSKOLIN; TUBERIN; ELONGATION FACTOR 1;

ADULT; AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE SILENCING; HIPPOCAMPAL SLICE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; VERY ELDERLY; 129 MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION; GENETICS; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; PEPTIDE ELONGATION FACTOR 1;

EID: 84986557839     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160036     Document Type: Article

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