Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β

Journal of Neuroscience

Volumn 34, Issue 36, 2014, Pages 12230-12238

  Ma, Tao ^a   Chen, Yiran ^a   Vingtdeux, Valerie ^b   Zhao, Haitian ^b   Viollet, Benoit ^c,d,e   Marambaud, Philippe ^b   Klann, Eric ^a  

^a NEW YORK UNIVERSITY   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c INSTITUT COCHIN   (France)

^d CNRS   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Alzheimer's disease; Long term potentiation; Neurodegeneration; Protein synthesis; Signaling; Translation

Indexed keywords

ALZHEIMER'S DISEASE; LONG-TERM POTENTIATION; NEURODEGENERATION; PROTEIN SYNTHESIS; SIGNALING; TRANSLATION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMP-ACTIVATED PROTEIN KINASES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELLS, CULTURED; ELONGATION FACTOR 2 KINASE; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; LONG-TERM SYNAPTIC DEPRESSION; MALE; MICE; MICE, INBRED C57BL; PEPTIDE ELONGATION FACTOR 2; PRESENILIN-1; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIMIDINES; SIGNAL TRANSDUCTION;

EID: 84906910072     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1694-14.2014     Document Type: Article

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