Glucagon-like peptide-1 cleavage product GLP-1(9-36) amide rescues synaptic plasticity and memory deficits in Alzheimer's disease model mice

Journal of Neuroscience

Volumn 32, Issue 40, 2012, Pages 13701-13708

  Ma, Tao ^a   Du, Xueliang ^b   Pick, Joseph E ^a   Sui, Guangzhi ^b   Brownlee, Michael ^b   Klann, Eric ^a  

^a NEW YORK UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN [1-42]; AMYLOID PRECURSOR PROTEIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 CLEAVAGE PRODUCT; GLYCOGEN SYNTHASE KINASE 3BETA; PRESENILIN 1; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEAR; FEMALE; FREEZING; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIOXIDANTS; ASSOCIATION LEARNING; CA3 REGION, HIPPOCAMPAL; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; EXCITATORY POSTSYNAPTIC POTENTIALS; FEAR; FEMALE; GLUCAGON-LIKE PEPTIDE 1; GLYCOGEN SYNTHASE KINASE 3; MALE; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NEURONAL PLASTICITY; NOOTROPIC AGENTS; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDE FRAGMENTS; PEPTIDES; PRESENILIN-1; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UBIQUINONE;

EID: 84866972198     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2107-12.2012     Document Type: Article

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