Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways

Oxidative Medicine and Cellular Longevity

Volumn 2016, Issue , 2016, Pages

  Li, Kang ^a   Gesang, Luobu ^a   Dan, Zeng ^a   Gusang, Lamu ^a  

^a People's Hospital of Tibet Autonomous Region   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; PROTEINS;

EPIDERMAL GROWTH FACTOR RECEPTORS; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2; HYPOXIC ENVIRONMENTS; IMMUNOLOGICAL RESPONSE; MOLECULAR MECHANISM; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ANALYSIS; TRANSCRIPTOME ANALYSIS;

GENE EXPRESSION;

EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HEMOGLOBIN; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; TRANSCRIPTOME; GRB2 PROTEIN, HUMAN; PEPTIDE; PTPN11 PROTEIN, HUMAN;

ADULT; AGE; ALTITUDE; ARTICLE; BODY MASS; DIASTOLIC BLOOD PRESSURE; DOWN REGULATION; DRINKING BEHAVIOR; ELECTRON MICROSCOPY; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION STUDY; HAN CHINESE; HEART RATE; HEMOGLOBIN BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOXIA; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE VILLUS; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; OXIDATIVE STRESS; OXYGEN SATURATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SMOKING; TIBETAN (PEOPLE); TRANSCRIPTOMICS; CELL HYPOXIA; CLUSTER ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; GENETICS; HUMAN CHROMOSOME; HUMAN GENOME; INTESTINE; METABOLISM; MIDDLE AGED; PATHOLOGY; REPRODUCIBILITY; SIGNAL TRANSDUCTION; STAINING; TIBET; ULTRASTRUCTURE; UPREGULATION;

ADULT; CELL HYPOXIA; CHROMOSOMES, HUMAN; CLUSTER ANALYSIS; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENE REGULATORY NETWORKS; GENOME, HUMAN; GRB2 ADAPTOR PROTEIN; HUMANS; INTESTINAL MUCOSA; INTESTINES; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PEPTIDES; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; STAINING AND LABELING; TIBET; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84984671892     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2016/6967396     Document Type: Article

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