Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

EBioMedicine

Volumn 3, Issue , 2016, Pages 43-53

  Khan, Abrar Ul Haq ^a   Rathore, Moeez G ^a   Allende Vega, Nerea ^a   Vo, Dang Nghiem ^a   Belkhala, Sana ^a   Orecchioni, Stefania ^b   Talarico, Giovanna ^b   Bertolini, Francesco ^b   Cartron, Guillaume ^c   Lecellier, Charles Henri ^d,e   Villalba, Martin ^a,c  

^a INSERM   (France)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c MONTPELLIER UNIVERSITY HOSPITAL   (France)

^d INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^e UNIV MONTPELLIER   (France)

Author keywords

Antioxidant response elements (ARE); ERK5; MEF2; miR 23; Mitochondria; Oxidative phosphorylation (OXPHOS)

Indexed keywords

DICHLOROACETIC ACID; GLUCOSE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; MICRORNA; MICRORNA 23A; MITOGEN ACTIVATED PROTEIN KINASE 7; MYOCYTE ENHANCER FACTOR 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; TRANSCRIPTOME; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ANTIOXIDANT; KEAP1 PROTEIN, HUMAN; MIRN23 MICRORNA, HUMAN; SIGNAL PEPTIDE;

3' UNTRANSLATED REGION; ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT GENE; ARTICLE; CELL COUNTING; CELL VIABILITY ASSAY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; TRANSIENT TRANSFECTION; TUMOR XENOGRAFT; WESTERN BLOTTING; ANTIBODY SPECIFICITY; ANTIOXIDANT RESPONSIVE ELEMENT; BIOLOGICAL MODEL; CHEMISTRY; GENETICS; LEUKEMIA; METABOLISM; MITOCHONDRION; RNA INTERFERENCE; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LEUKEMIA; MICRORNAS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE 7; MODELS, BIOLOGICAL; ORGAN SPECIFICITY; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, MESSENGER;

EID: 84958852021     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.11.045     Document Type: Article

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