Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment

World Journal of Gastroenterology

Volumn 17, Issue 12, 2011, Pages 1584-1593

  Zhou, Qi Quan ^a   Yang, Ding Zhou ^a,b   Luo, Yong Jun ^a   Li, Su Zhi ^b   Liu, Fu Yu ^a   Wang, Guan Song ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Research Center of Mountain Sickness General Hospital of Tibetan Military Area   (China)

Author keywords

Bacterial translocation; Endotoxin; Glutamine; High altitude; Hypoxia; Intestinal mucosal injury; Starvation

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); ENDOTOXIN; GLUTAMINE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ALTITUDE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL TRANSLOCATION; CONTROLLED STUDY; HYPOXIA; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE VILLUS; MALE; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79955932802     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i12.1584     Document Type: Article

References (32)

1. Bailey DM, Bärtsch P, Knauth M, Baumgartner RW. Emerging concepts in acute mountain sickness and high-altitude cerebral edema: from the molecular to the morphological. Cell Mol Life Sci 2009; 66: 3583-3594
2. Hanaoka M, Droma Y, Ota M, Ito M, Katsuyama Y, Kubo K. Polymorphisms of human vascular endothelial growth factor gene in high-altitude pulmonary oedema susceptible subjects. Respirology 2009; 14: 46-52
3. Burtscher M. High-altitude cerebral effects: risks and mechanisms. Lancet Neurol 2009; 8: 604-605; author reply 605
4. Yang DZ, Zhou QQ, Li SZ, Zheng BH, Gao YQ, Jiang SH, Huang XW. Gastrointestinal dysfunction in acute severe mountain sickness and its relation with multiple organ dysfunction syndrome. Zhongguo Weizhongbing Jijiu Yixue 2009; 21: 95-98
5. Suliburk J, Helmer K, Moore F, Mercer D. The gut in systemic inflammatory response syndrome and sepsis. Enzyme systems fighting multiple organ failure. Eur Surg Res 2008; 40: 184-189
6. Urban Z, Hucthagowder V, Schürmann N, Todorovic V, Zilberberg L, Choi J, Sens C, Brown CW, Clark RD, Holland KE, Marble M, Sakai LY, Dabovic B, Rifkin DB, Davis EC. Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development. Am J Hum Genet 2009; 85: 593-605
7. Swank GM, Deitch EA. Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg 1996; 20: 411-417
8. Murata H, Yagi M, Kubota M, Ushiki T. Embryonic development of the myenteric nerve plexus in the rat small intestine as revealed by light and scanning electron microscopy. Arch Histol Cytol 2003; 66: 453-468
9. Ogiolda L, Wanke R, Rottmann O, Hermanns W, Wolf E. Intestinal dimensions of mice divergently selected for body weight. Anat Rec 1998; 250: 292-299
10. Groos S, Reale E, Luciano L. General suitability of techniques for in situ detection of apoptosis in small intestinal epithelium. Anat Rec A Discov Mol Cell Evol Biol 2003; 272: 503-513
11. Vyas D, Robertson CM, Stromberg PE, Martin JR, Dunne WM, Houchen CW, Barrett TA, Ayala A, Perl M, Buchman TG, Coopersmith CM. Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine. Histol Histopathol 2007; 22: 623-630
12. Habold C, Dunel-Erb S, Chevalier C, Laurent P, Le Maho Y, Lignot JH. Observations of the intestinal mucosa using environmental scanning electron microscopy (ESEM); comparison with conventional scanning electron microscopy (CSEM). Micron 2003; 34: 373-379
13. Morroni M, Cangiotti AM, Cinti S. Brush cells in the human duodenojejunal junction: an ultrastructural study. J Anat 2007; 211: 125-131
14. Endo S, Aikawa N, Fujishima S, Sekine I, Kogawa K, Yamamoto Y, Kushimoto S, Yukioka H, Kato N, Totsuka K, Kikuchi K, Ikeda T, Ikeda K, Yamada H, Harada K, Satomura S. Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study. J Infect Chemother 2008; 14: 244-249
15. Su Y, Wu S, Fan Y, Jin J, Zhang Z. The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier. J Gastroenterol Hepatol 2009; 24: 1451-1456
16. Prasad K, Lee P, Mantha SV, Kalra J, Prasad M, Gupta JB. Detection of ischemia-reperfusion cardiac injury by cardiac muscle chemiluminescence. Mol Cell Biochem 1992; 115: 49-58
17. Shen L. Functional morphology of the gastrointestinal tract. Curr Top Microbiol Immunol 2009; 337: 1-35
18. Al-Sadi R, Boivin M, Ma T. Mechanism of cytokine modulation of epithelial tight junction barrier. Front Biosci 2009; 14: 2765-2778
19. Visser J, Rozing J, Sapone A, Lammers K, Fasano A. Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms. Ann N Y Acad Sci 2009; 1165: 195-205
20. Yang HY, Liu SL, Ibrahim SA, Zhao L, Jiang JL, Sun WF, Ren FZ. Oral administration of live Bifidobacterium substrains isolated from healthy centenarians enhanced immune function in BALB/c mice. Nutr Res 2009; 29: 281-289
21. Kleessen B, Schroedl W, Stueck M, Richter A, Rieck O, Krueger M. Microbial and immunological responses relative to high-altitude exposure in mountaineers. Med Sci Sports Exerc 2005; 37: 1313-1318
22. Selsted ME, Miller SI, Henschen AH, Ouellette AJ. Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol 1992; 118: 929-936
23. Recavarren-Arce S, Ramirez-Ramos A, Gilman RH, Chinga-Alayo E, Watanabe-Yamamoto J, Rodriguez-Ulloa C, Miyagui J, Passaro DJ, Eza D. Severe gastritis in the Peruvian Andes. Histopathology 2005; 46: 374-379
24. Wang ZT, Yao YM, Xiao GX, Sheng ZY. Risk factors of development of gut-derived bacterial translocation in thermally injured rats. World J Gastroenterol 2004; 10: 1619-1624
25. Diebel LN, Liberati DM, Taub JS, Diglio CA, Brown WJ. Intestinal epithelial cells modulate PMN activation and apoptosis following bacterial and hypoxic challenges. J Trauma 2005; 58: 1126-1133
26. Wang XD, Soltesz V, Andersson R. Cisapride prevents enteric bacterial overgrowth and translocation by improvement of intestinal motility in rats with acute liver failure. Eur Surg Res 1996; 28: 402-412
27. Luk GD, Bayless TM, Baylin SB. Plasma postheparin diamine oxidase. Sensitive provocative test for quantitating length of acute intestinal mucosal injury in the rat. J Clin Invest 1983; 71: 1308-1315
28. Moriyama K, Kouchi Y, Morinaga H, Irimura K, Hayashi T, Ohuchida A, Goto T, Yoshizawa Y. Diamine oxidase, a plasma biomarker in rats to GI tract toxicity of oral fluorouracil anti-cancer drugs. Toxicology 2006; 217: 233-239
29. Senthil M, Brown M, Xu DZ, Lu Q, Feketeova E, Deitch EA. Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model. J Trauma 2006; 60: 958-965; discussion 965-967
30. Deitch EA, Xu D, Kaise VL. Role of the gut in the development of injury- and shock induced SIRS and MODS: the gutlymph hypothesis, a review. Front Biosci 2006; 11: 520-528
31. Shi C, Zhao X, Lagergren A, Sigvardsson M, Wang X, Andersson R. Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis. Scand J Gastroenterol 2006; 41: 472-480
32. Velasco N. Gut barrier in the critically ill patient: facts and trends. Rev Med Chil 2006; 134: 1033-1039