Indomethacin-induced generation of reactive oxygen species leads to epithelial cell injury before the formation of intestinal lesions in mice

Journal of Physiology and Pharmacology

Volumn 65, Issue 3, 2014, Pages 435-440

  Tomita, T ^a,b   Sadakata, H ^a,b   Tamura, M ^a   Matsui, H ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Timelapse Vision Inc   (Japan)

Author keywords

Intestinal injury; Intestinal villi; Manganese superoxide dismutase; Nonsteroidal anti inflammatory drugs; Prostaglandins; Reactive oxygen species; Rebamipide

Indexed keywords

INDOMETACIN; REACTIVE OXYGEN METABOLITE; REBAMIPIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; IMAGING; INTESTINE INJURY; INTESTINE MUCOSA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; ULCEROGENESIS; ANIMAL; DRUG EFFECTS; EPITHELIUM CELL; INJURIES; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOLOGY; SMALL INTESTINE;

ANIMALS; EPITHELIAL CELLS; INDOMETHACIN; INTESTINE, SMALL; MALE; MICE; MICE, INBRED ICR; REACTIVE OXYGEN SPECIES;

EID: 84902475959     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

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