Transcriptome analysis of GVHD reveals aurora kinase a as a targetable pathway for disease prevention

Science Translational Medicine

Volumn 7, Issue 315, 2015, Pages

  Furlan, Scott N ^a   Watkins, Benjamin ^b   Tkachev, Victor ^a   Flynn, Ryan ^c   Cooley, Sarah ^c   Ramakrishnan, Swetha ^b   Singh, Karnail ^b   Giver, Cindy ^b   Hamby, Kelly ^b   Stempora, Linda ^b   Garrett, Aneesah ^b   Chen, Jingyang ^a   Betz, Kayla M ^a   Ziegler, Carly G K ^d   Tharp, Gregory K ^e   Bosinger, Steven E ^e   Promislow, Daniel E L ^f   Miller, Jeffrey S ^c   Waller, Edmund K ^b   Blazar, Bruce R ^c   Kean, Leslie S ^a   more..

^a UNIVERSITY OF WASHINGTON   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e EMORY UNIVERSITY   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; METHOTREXATE; NOTCH RECEPTOR; RAPAMYCIN; TACROLIMUS; TRANSCRIPTOME;

ACUTE GRAFT VERSUS HOST DISEASE; ALLOIMMUNITY; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD3+ T LYMPHOCYTE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HUMAN; IMMUNOPROPHYLAXIS; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; MICROARRAY ANALYSIS; MONOTHERAPY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PYROPTOSIS; REGULATORY T LYMPHOCYTE; SURVIVAL; TRANSCRIPTOMICS; ENZYMOLOGY; GENETICS; GRAFT VS HOST DISEASE; METABOLISM;

AURORA KINASE A; GENE EXPRESSION; GRAFT VS HOST DISEASE; HUMANS; METHOTREXATE; SIROLIMUS; TACROLIMUS; TRANSCRIPTOME;

EID: 84954450570     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aad3231     Document Type: Article

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