Ebselen by modulating oxidative stress improves hypoxia-induced macroglial müller cell and vascular injury in the retina

Experimental Eye Research

Volumn 136, Issue , 2015, Pages 1-8

  Tan, Sih Min ^a   Deliyanti, Devy ^b   Figgett, William A ^b   Talia, Dean M ^b   de Haan, Judy B ^a,b   Wilkinson Berka, Jennifer L ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Ebselen; Glia; Oxidative stress; Reactive oxygen species; Retinopathy; Vasculature

Indexed keywords

DIMETHYL SULFOXIDE; EBSELEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE PEROXIDASE 1; HEME OXYGENASE 1; HYDROETHIDINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; VASCULOTROPIN; ANTIOXIDANTS; AZOLES; BIOLOGICAL MARKERS; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; NERVE TISSUE PROTEINS; ORGANOSELENIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

ANIMAL CELL; ARTICLE; BLOOD VESSEL INJURY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLOW CYTOMETRY; GLIOSIS; HYPOXIA; MICROVASCULATURE; MUELLER CELL; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OXIDATIVE STRESS; OXYGEN-INDUCED RETINOPATHY; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; ANIMALS; ANIMALS, NEWBORN; ANOXIA; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUG EFFECTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPENDYMOGLIAL CELLS; METABOLISM; MICE; MICE, INBRED C57BL; RATS; RATS, SPRAGUE-DAWLEY; RETINAL DEGENERATION; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; VASCULAR SYSTEM INJURIES;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; ANTIOXIDANTS; AZOLES; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPENDYMOGLIAL CELLS; FLOW CYTOMETRY; GLIOSIS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; ORGANOSELENIUM COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RETINAL DEGENERATION; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; SUPEROXIDES; VASCULAR SYSTEM INJURIES;

EID: 84928658822     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2015.04.015     Document Type: Article

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