Immediate dysfunction of vaccine-elicited CD8+ T cells primed in the absence of CD4+ T cells

Journal of Immunology

Volumn 197, Issue 5, 2016, Pages 1809-1822

  Provine, Nicholas M ^a   Larocca, Rafael A ^a   Aid, Malika ^a   Penaloza MacMaster, Pablo ^a   Badamchi Zadeh, Alexander ^a   Borducchi, Erica N ^a   Yates, Kathleen B ^b   Abbink, Peter ^a   Kirilova, Marinela ^a   Ng'ang'a, David ^a   Bramson, Jonathan ^c,d,e   Haining, W Nicholas ^c,f,g   Barouch, Dan H ^a,h  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c MCMASTER UNIVERSITY   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

^e MCMASTER UNIVERSITY   (Canada)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g BOSTON CHILDREN S HOSPITAL   (United States)

^h MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD27 ANTIGEN; GAMMA INTERFERON; LEUKOSIALIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; POXVIRUS VECTOR; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; CYTOKINE; VACCINE;

ANALYTICAL PARAMETERS; ANERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL REPROGRAMMING TECHNIQUE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; EFFECTOR CELL; EX VIVO STUDY; GENE SET ENRICHMENT ANALYSIS; GENETIC ANALYSIS; IMMUNOGENICITY; IMMUNOLOGICAL PARAMETERS; IMMUNOREGULATION; INTRACELLULAR SIGNALING; LEUKOPENIA; LYMPHOCYTE DEPLETION; LYMPHOCYTE DIFFERENTIATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T CELL EXHAUSTION; T LYMPHOCYTE IMMEDIATE DYSFUNCTION; TIME SERIES ANALYSIS; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; VACCINATION; ADENOVIRIDAE; ANIMAL; C57BL MOUSE; FEMALE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; IMMUNIZATION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY;

ADENOVIRIDAE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; GENE EXPRESSION REGULATION; GENETIC VECTORS; IMMUNIZATION; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; VACCINES;

EID: 84983766421     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600591     Document Type: Article

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