CD154 and IL-2 Signaling of CD4+ T Cells Play a Critical Role in Multiple Phases of CD8+ CTL Responses Following Adenovirus Vaccination

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Sokke Umeshappa, Channakeshava ^a,c   Hebbandi Nanjundappa, Roopa ^a,d   Xie, Yufeng ^a   Freywald, Andrew ^a   Deng, Yulin ^b   Ma, Hong ^b   Xiang, Jim ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b BEIJING INSTITUTE OF TECHNOLOGY   (China)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD4 ANTIGEN; CD40 LIGAND; CD8 ANTIGEN; CYTOKINE; INTERLEUKIN 2; OVALBUMIN; PROGRAMMED DEATH 1 RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; GENE EXPRESSION; INTRACELLULAR SIGNALING; LYMPHOCYTE STRUCTURE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; GENETIC VECTORS; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; OVALBUMIN; SIGNAL TRANSDUCTION; VACCINATION;

ADENOVIRIDAE; ANIMALIA; MUS; MUS MUSCULUS;

EID: 84867172509     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047004     Document Type: Article

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