Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

Nature Medicine

Volumn 20, Issue 10, 2014, Pages 1126-1129

  Stanley, Daphne A ^a   Honko, Anna N ^a,b   Asiedu, Clement ^a   Trefry, John C ^b   Lau Kilby, Annie W ^a   Johnson, Joshua C ^a,b   Hensley, Lisa ^a,b   Ammendola, Virginia ^c   Abbate, Adele ^c   Grazioli, Fabiana ^c   Foulds, Kathryn E ^a   Cheng, Cheng ^a   Wang, Lingshu ^a   Donaldson, Mitzi M ^a   Colloca, Stefano ^c   Folgori, Antonella ^c   Roederer, Mario ^a   Nabel, Gary J ^a,g   Mascola, John ^a   Nicosia, Alfredo ^c,d,e   Cortese, Riccardo ^f   Koup, Richard A ^a   Sullivan, Nancy J ^a   more..

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c Okairos ^*  (Italy)

^d CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f Keires AG   (Switzerland)

^g SANOFI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VACCINE; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR; EBOLA VACCINE; VIRUS RNA;

ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHIMPANZEE; CYTOKINE RELEASE; EBOLA HEMORRHAGIC FEVER; GENETIC DISTANCE; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOLOGICAL MEMORY; LETHAL DOSE; MARBURG VIRUS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; VACCINATION; VESICULOVIRUS; VIRAL CLEARANCE; ANIMAL; BLOOD; EBOLAVIRUS; FEMALE; GENE VECTOR; GENETICS; HEMORRHAGIC FEVER, EBOLA; HUMAN; HUMAN ADENOVIRUS C; IMMUNIZATION; IMMUNOLOGY; MACACA FASCICULARIS; PAN TROGLODYTES; SATELLITE VIRUS; SIMIAN VIRUS; TIME; VACCINIA VIRUS; VIROLOGY;

ADENOVIRIDAE; ANIMALIA; CHIMPANZEE ADENOVIRUS; EBOLA VIRUS; HUMAN ADENOVIRUS TYPE 5; MACACA; PAN; ZAIRE EBOLAVIRUS;

ADENOVIRUS VACCINES; ADENOVIRUSES, HUMAN; ADENOVIRUSES, SIMIAN; ANIMALS; DEFECTIVE VIRUSES; EBOLA VACCINES; EBOLAVIRUS; FEMALE; GENETIC VECTORS; HEMORRHAGIC FEVER, EBOLA; HUMANS; IMMUNIZATION, SECONDARY; MACACA FASCICULARIS; PAN TROGLODYTES; RNA, VIRAL; TIME FACTORS; VACCINIA VIRUS;

EID: 84907263544     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3702     Document Type: Article

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