Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time

Biotechnology and Bioengineering

Volumn 113, Issue 10, 2016, Pages 2241-2253

  Feichtinger, Julia ^a,b   Hernández, Inmaculada ^a   Fischer, Christoph ^a,b   Hanscho, Michael ^a   Auer, Norbert ^c   Hackl, Matthias ^c   Jadhav, Vaibhav ^a   Baumann, Martina ^a   Krempl, Peter M ^a,b   Schmidl, Christian ^d   Farlik, Matthias ^d   Schuster, Michael ^d   Merkel, Angelika ^e   Sommer, Andreas ^f   Heath, Simon ^e   Rico, Daniel ^g   Bock, Christoph ^d   Thallinger, Gerhard G ^a,b   Borth, Nicole ^a,c  

^a AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^e CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^f RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^g Structural Biology and Biocomputing Programme   (Spain)

Author keywords

Chinese hamster ovary cells; DNA methylation; epigenome; genome variation; histone modifications

Indexed keywords

ALKYLATION; BATCH CELL CULTURE; CELL CULTURE; CELLS; CYTOLOGY; DNA; GENE EXPRESSION; METHYLATION; PROTEINS;

CHINESE HAMSTER OVARY CELLS; DNA METHYLATION; EPIGENOMES; GENOME VARIATION; HISTONE MODIFICATION;

GENES;

BACTERIUM CULTURE; BIOPROCESS; CELL LINE; CHINESE HAMSTER; DNA METHYLATION; DNA STRUCTURE; EPIGENETICS; GENE EXPRESSION; GROWTH CURVE; HISTONE MODIFICATION; HUMAN; HUMAN CELL; INDEL MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84983752981     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25990     Document Type: Article

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