-
1
-
-
41849140828
-
Recombinant protein therapeutics from CHO cells-20 years and counting
-
Jayapal P.K., Wlaschin F.K., Hu W.-S., Yap M.G.S. Recombinant protein therapeutics from CHO cells-20 years and counting. Chem Eng Prog 2007, 103:40-47.
-
(2007)
Chem Eng Prog
, vol.103
, pp. 40-47
-
-
Jayapal, P.K.1
Wlaschin, F.K.2
Hu, W.-S.3
Yap, M.G.S.4
-
2
-
-
77956690413
-
Biopharmaceutical benchmarks 2010
-
Walsh G. Biopharmaceutical benchmarks 2010. Nat Biotechnol 2010, 28:917-924.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 917-924
-
-
Walsh, G.1
-
3
-
-
79961191745
-
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
-
Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M., Wang W., Hammond S., et al. The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol 2011, 29:735-741.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 735-741
-
-
Xu, X.1
Nagarajan, H.2
Lewis, N.E.3
Pan, S.4
Cai, Z.5
Liu, X.6
Chen, W.7
Xie, M.8
Wang, W.9
Hammond, S.10
-
4
-
-
34948835837
-
A scaffold for the Chinese hamster genome
-
Wlaschin K.F., Hu W. A scaffold for the Chinese hamster genome. Biotechnol Bioeng 2007, 98:429-439.
-
(2007)
Biotechnol Bioeng
, vol.98
, pp. 429-439
-
-
Wlaschin, K.F.1
Hu, W.2
-
5
-
-
79251576820
-
Genomic sequencing and analysis of a Chinese hamster ovary cell line using illumina sequencing technology
-
Hammond S., Swanberg J.C., Kaplarevic M., Lee K.H. Genomic sequencing and analysis of a Chinese hamster ovary cell line using illumina sequencing technology. BMC Genomics 2011, 12:67.
-
(2011)
BMC Genomics
, vol.12
, pp. 67
-
-
Hammond, S.1
Swanberg, J.C.2
Kaplarevic, M.3
Lee, K.H.4
-
6
-
-
84859908354
-
Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org
-
Hammond S., Kaplarevic M., Borth N., Betenbaugh M.J., Lee K.H. Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org. Biotechnol Bioeng 2012, 109:1353-1356.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1353-1356
-
-
Hammond, S.1
Kaplarevic, M.2
Borth, N.3
Betenbaugh, M.J.4
Lee, K.H.5
-
7
-
-
80051786735
-
A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies
-
Kim M., O'Callaghan P.M., Droms K.A., James D.C. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies. Biotechnol Bioeng 2011, 108:2434-2446.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 2434-2446
-
-
Kim, M.1
O'Callaghan, P.M.2
Droms, K.A.3
James, D.C.4
-
8
-
-
84859882580
-
Construction of BAC-based physical map and analysis of chromosome rearrangement in Chinese hamster ovary cell lines
-
Cao Y., Kimura S., Itoi T., Honda K., Ohtake H., Omasa T. Construction of BAC-based physical map and analysis of chromosome rearrangement in Chinese hamster ovary cell lines. Biotechnol Bioeng 2012, 109:1357-1367.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1357-1367
-
-
Cao, Y.1
Kimura, S.2
Itoi, T.3
Honda, K.4
Ohtake, H.5
Omasa, T.6
-
9
-
-
57749195712
-
RNA-Seq: a revolutionary tool for transcriptomics
-
Wang Z., Gerstein M., Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet 2009, 10:57-63.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 57-63
-
-
Wang, Z.1
Gerstein, M.2
Snyder, M.3
-
10
-
-
25144479858
-
EST sequencing for gene discovery in Chinese hamster ovary cells
-
Wlaschin K.F., Nissom P.M., Gatti M.D.L., Ong P.F., Arleen S., Tan K.S., Rink A., Cham B., Wong K., Yap M., et al. EST sequencing for gene discovery in Chinese hamster ovary cells. Biotechnol Bioeng 2005, 91:592-606.
-
(2005)
Biotechnol Bioeng
, vol.91
, pp. 592-606
-
-
Wlaschin, K.F.1
Nissom, P.M.2
Gatti, M.D.L.3
Ong, P.F.4
Arleen, S.5
Tan, K.S.6
Rink, A.7
Cham, B.8
Wong, K.9
Yap, M.10
-
11
-
-
56749148174
-
Quality assessment of cross-species hybridization of CHO transcriptome on a mouse DNA oligo microarray
-
Yee J.C., Wlaschin K.F., Chuah S.H., Nissom P.M., Hu W.-S. Quality assessment of cross-species hybridization of CHO transcriptome on a mouse DNA oligo microarray. Biotechnol Bioeng 2008, 101:1359-1365.
-
(2008)
Biotechnol Bioeng
, vol.101
, pp. 1359-1365
-
-
Yee, J.C.1
Wlaschin, K.F.2
Chuah, S.H.3
Nissom, P.M.4
Hu, W.-S.5
-
12
-
-
58149214612
-
Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells
-
Yee J.C., Gerdtzen Z.P., Hu W.-S. Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells. Biotechnol Bioeng 2009, 102:246-263.
-
(2009)
Biotechnol Bioeng
, vol.102
, pp. 246-263
-
-
Yee, J.C.1
Gerdtzen, Z.P.2
Hu, W.-S.3
-
13
-
-
77957123642
-
Transcriptomic responses to sodium chloride-induced osmotic stress: a study of industrial fed-batch CHO cell cultures
-
Shen D., Kiehl T.R., Khattak S.F., Li Z.J., He A., Kayne P.S., Patel V., Neuhaus I.M., Sharfstein S.T. Transcriptomic responses to sodium chloride-induced osmotic stress: a study of industrial fed-batch CHO cell cultures. Biotechnol Prog 2010, 26:1104-1115.
-
(2010)
Biotechnol Prog
, vol.26
, pp. 1104-1115
-
-
Shen, D.1
Kiehl, T.R.2
Khattak, S.F.3
Li, Z.J.4
He, A.5
Kayne, P.S.6
Patel, V.7
Neuhaus, I.M.8
Sharfstein, S.T.9
-
14
-
-
80051471205
-
Development and characterization of a Chinese hamster ovary cell-specific oligonucleotide microarray
-
Melville M., Doolan P., Mounts W., Barron N., Hann L., Leonard M., Clynes M., Charlebois T. Development and characterization of a Chinese hamster ovary cell-specific oligonucleotide microarray. Biotechnol Lett 2011, 33:1773-1779.
-
(2011)
Biotechnol Lett
, vol.33
, pp. 1773-1779
-
-
Melville, M.1
Doolan, P.2
Mounts, W.3
Barron, N.4
Hann, L.5
Leonard, M.6
Clynes, M.7
Charlebois, T.8
-
16
-
-
77955081300
-
Into the unknown: expression profiling without genome sequence information in CHO by next generation sequencing
-
Birzele F., Schaub J., Rust W., Clemens C., Baum P., Kaufmann H., Weith A., Schulz T.W., Hildebrandt T. Into the unknown: expression profiling without genome sequence information in CHO by next generation sequencing. Nucleic Acids Res 2010, 38:3999-4010.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 3999-4010
-
-
Birzele, F.1
Schaub, J.2
Rust, W.3
Clemens, C.4
Baum, P.5
Kaufmann, H.6
Weith, A.7
Schulz, T.W.8
Hildebrandt, T.9
-
17
-
-
77949359805
-
Reaching the depth of the Chinese hamster ovary cell transcriptome
-
Jacob N.M., Kantardjieff A., Yusufi F.N.K., Retzel E.F., Mulukutla B.C., Chuah S.H., Yap M., Hu W.-S. Reaching the depth of the Chinese hamster ovary cell transcriptome. Biotechnol Bioeng 2010, 105:1002-1009.
-
(2010)
Biotechnol Bioeng
, vol.105
, pp. 1002-1009
-
-
Jacob, N.M.1
Kantardjieff, A.2
Yusufi, F.N.K.3
Retzel, E.F.4
Mulukutla, B.C.5
Chuah, S.H.6
Yap, M.7
Hu, W.-S.8
-
18
-
-
80054106553
-
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing
-
Becker J., Hackl M., Rupp O., Jakobi T., Schneider J., Szczepanowski R., Bekel T., Borth N., Goesmann A., Grillari J., et al. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. J Biotechnol 2011, 156:227-235.
-
(2011)
J Biotechnol
, vol.156
, pp. 227-235
-
-
Becker, J.1
Hackl, M.2
Rupp, O.3
Jakobi, T.4
Schneider, J.5
Szczepanowski, R.6
Bekel, T.7
Borth, N.8
Goesmann, A.9
Grillari, J.10
-
19
-
-
84859890792
-
CGCDB: a web-based resource for the investigation of gene coexpression in CHO cell culture
-
Clarke C., Doolan P., Barron N., Meleady P., Madden S.F., DiNino D., Leonard M., Clynes M. CGCDB: a web-based resource for the investigation of gene coexpression in CHO cell culture. Biotechnol Bioeng 2012, 109:1368-1370.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1368-1370
-
-
Clarke, C.1
Doolan, P.2
Barron, N.3
Meleady, P.4
Madden, S.F.5
DiNino, D.6
Leonard, M.7
Clynes, M.8
-
20
-
-
45049085323
-
MicroRNAs as targets for engineering of CHO cell factories
-
Müller D., Katinger H., Grillari J. MicroRNAs as targets for engineering of CHO cell factories. Trends Biotechnol 2008, 26:359-365.
-
(2008)
Trends Biotechnol
, vol.26
, pp. 359-365
-
-
Müller, D.1
Katinger, H.2
Grillari, J.3
-
21
-
-
34250307966
-
Initial identification of low temperature and culture stage induction of miRNA expression in suspension CHO-K1 cells
-
Gammell P., Barron N., Kumar N., Clynes M. Initial identification of low temperature and culture stage induction of miRNA expression in suspension CHO-K1 cells. J Biotechnol 2007, 130:213-218.
-
(2007)
J Biotechnol
, vol.130
, pp. 213-218
-
-
Gammell, P.1
Barron, N.2
Kumar, N.3
Clynes, M.4
-
22
-
-
78650210790
-
Conserved microRNAs in Chinese hamster ovary cell lines
-
Johnson K.C., Jacob N.M., Nissom P.M., Hackl M., Lee L.H., Yap M., Hu W.-S. Conserved microRNAs in Chinese hamster ovary cell lines. Biotechnol Bioeng 2011, 108:475-480.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 475-480
-
-
Johnson, K.C.1
Jacob, N.M.2
Nissom, P.M.3
Hackl, M.4
Lee, L.H.5
Yap, M.6
Hu, W.-S.7
-
23
-
-
79955132774
-
Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering
-
Hackl M., Jakobi T., Blom J., Doppmeier D., Brinkrolf K., Szczepanowski R., Bernhart S.H., Höner Zu Siederdissen C., Bort J.A H., Wieser M., et al. Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering. J Biotechnol 2011, 153:62-75.
-
(2011)
J Biotechnol
, vol.153
, pp. 62-75
-
-
Hackl, M.1
Jakobi, T.2
Blom, J.3
Doppmeier, D.4
Brinkrolf, K.5
Szczepanowski, R.6
Bernhart, S.H.7
Höner Zu Siederdissen, C.8
Bort, J.A.H.9
Wieser, M.10
-
24
-
-
84862778524
-
Profiling conserved microRNA expression in recombinant CHO cell lines using illumina sequencing
-
Hammond S., Swanberg J.C., Polson S.W., Lee K.H. Profiling conserved microRNA expression in recombinant CHO cell lines using illumina sequencing. Biotechnol Bioeng 2012, 109:1371-1375.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1371-1375
-
-
Hammond, S.1
Swanberg, J.C.2
Polson, S.W.3
Lee, K.H.4
-
25
-
-
78651507094
-
Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7
-
Barron N., Kumar N., Sanchez N., Doolan P., Clarke C., Meleady P., O'Sullivan F., Clynes M. Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7. J Biotechnol 2011, 151:204-211.
-
(2011)
J Biotechnol
, vol.151
, pp. 204-211
-
-
Barron, N.1
Kumar, N.2
Sanchez, N.3
Doolan, P.4
Clarke, C.5
Meleady, P.6
O'Sullivan, F.7
Clynes, M.8
-
26
-
-
79956158579
-
A novel microRNA mmu-miR-466h affects apoptosis regulation in mammalian cells
-
Druz A., Chu C., Majors B., Santuary R., Betenbaugh M., Shiloach J. A novel microRNA mmu-miR-466h affects apoptosis regulation in mammalian cells. Biotechnol Bioeng 2011, 108:1651-1661.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 1651-1661
-
-
Druz, A.1
Chu, C.2
Majors, B.3
Santuary, R.4
Betenbaugh, M.5
Shiloach, J.6
-
28
-
-
77953850346
-
Protein reference mapping of dihydrofolate reductase-deficient CHO DG44 cell lines using 2-dimensional electrophoresis
-
Lee J.S., Park H.J., Kim Y.H., Lee G.M. Protein reference mapping of dihydrofolate reductase-deficient CHO DG44 cell lines using 2-dimensional electrophoresis. Proteomics 2010, 10:2292-2302.
-
(2010)
Proteomics
, vol.10
, pp. 2292-2302
-
-
Lee, J.S.1
Park, H.J.2
Kim, Y.H.3
Lee, G.M.4
-
29
-
-
84868324251
-
Proteomic analysis of Chinese hamster ovary cells
-
Baycin-Hizal D., Tabb D.L., Chaerkady R., Chen L., Lewis N.E., Nagarajan H., Sarkaria V., Kumar A., Wolozny D., Colao J., et al. Proteomic analysis of Chinese hamster ovary cells. J Proteome Res 2012, 11:5265-5276.
-
(2012)
J Proteome Res
, vol.11
, pp. 5265-5276
-
-
Baycin-Hizal, D.1
Tabb, D.L.2
Chaerkady, R.3
Chen, L.4
Lewis, N.E.5
Nagarajan, H.6
Sarkaria, V.7
Kumar, A.8
Wolozny, D.9
Colao, J.10
-
30
-
-
84859895625
-
Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics
-
Meleady P., Hoffrogge R., Henry M., Rupp O., Bort J.H., Clarke C., Brinkrolf K., Kelly S., Müller B., Doolan P., et al. Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics. Biotechnol Bioeng 2012, 109:1386-1394.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1386-1394
-
-
Meleady, P.1
Hoffrogge, R.2
Henry, M.3
Rupp, O.4
Bort, J.H.5
Clarke, C.6
Brinkrolf, K.7
Kelly, S.8
Müller, B.9
Doolan, P.10
-
31
-
-
33845948825
-
Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells
-
Nissom P.M., Sanny A., Kok Y.J., Hiang Y.T., Chuah S.H., Shing T.K., Lee Y.Y., Wong K.T.K., Hu W.-S., Sim M.Y.G., et al. Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells. Mol Biotechnol 2006, 34:125-140.
-
(2006)
Mol Biotechnol
, vol.34
, pp. 125-140
-
-
Nissom, P.M.1
Sanny, A.2
Kok, Y.J.3
Hiang, Y.T.4
Chuah, S.H.5
Shing, T.K.6
Lee, Y.Y.7
Wong, K.T.K.8
Hu, W.-S.9
Sim, M.Y.G.10
-
32
-
-
84862169586
-
Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases
-
Carlage T., Kshirsagar R., Zang L., Janakiraman V., Hincapie M., Lyubarskaya Y., Weiskopf A., Hancock W.S. Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases. Biotechnol Prog 2012, 28:814-823.
-
(2012)
Biotechnol Prog
, vol.28
, pp. 814-823
-
-
Carlage, T.1
Kshirsagar, R.2
Zang, L.3
Janakiraman, V.4
Hincapie, M.5
Lyubarskaya, Y.6
Weiskopf, A.7
Hancock, W.S.8
-
33
-
-
73149087029
-
Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment
-
Kantardjieff A., Jacob N.M., Yee J.C., Epstein E., Kok Y.-J., Philp R., Betenbaugh M., Hu W.-S. Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment. J Biotechnol 2010, 145:143-159.
-
(2010)
J Biotechnol
, vol.145
, pp. 143-159
-
-
Kantardjieff, A.1
Jacob, N.M.2
Yee, J.C.3
Epstein, E.4
Kok, Y.-J.5
Philp, R.6
Betenbaugh, M.7
Hu, W.-S.8
-
34
-
-
69749119326
-
Proteomic profiling of a high-producing Chinese hamster ovary cell culture
-
Carlage T., Hincapie M., Zang L., Lyubarskaya Y., Madden H., Mhatre R., Hancock W.S. Proteomic profiling of a high-producing Chinese hamster ovary cell culture. Anal Chem 2009, 81:7357-7362.
-
(2009)
Anal Chem
, vol.81
, pp. 7357-7362
-
-
Carlage, T.1
Hincapie, M.2
Zang, L.3
Lyubarskaya, Y.4
Madden, H.5
Mhatre, R.6
Hancock, W.S.7
-
35
-
-
77951555640
-
Microarray and proteomics expression profiling identifies several candidates, including the valosin-containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines
-
Doolan P., Meleady P., Barron N., Henry M., Gallagher R., Gammell P., Melville M., Sinacore M., McCarthy K., Leonard M., et al. Microarray and proteomics expression profiling identifies several candidates, including the valosin-containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines. Biotechnol Bioeng 2010, 106:42-56.
-
(2010)
Biotechnol Bioeng
, vol.106
, pp. 42-56
-
-
Doolan, P.1
Meleady, P.2
Barron, N.3
Henry, M.4
Gallagher, R.5
Gammell, P.6
Melville, M.7
Sinacore, M.8
McCarthy, K.9
Leonard, M.10
-
36
-
-
84870860793
-
Identifying the CHO secretome using mucin-type O-linked glycosylation and click-chemistry
-
Slade P.G., Hajivandi M., Bartel C.M., Gorfien S.F. Identifying the CHO secretome using mucin-type O-linked glycosylation and click-chemistry. J Proteome Res 2012, 11:6175-6186.
-
(2012)
J Proteome Res
, vol.11
, pp. 6175-6186
-
-
Slade, P.G.1
Hajivandi, M.2
Bartel, C.M.3
Gorfien, S.F.4
-
37
-
-
77949325755
-
Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity
-
North S.J., Huang H.-H., Sundaram S., Jang-Lee J., Etienne a T., Trollope A., Chalabi S., Dell A., Stanley P., Haslam S.M. Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. J Biol Chem 2010, 285:5759-5775.
-
(2010)
J Biol Chem
, vol.285
, pp. 5759-5775
-
-
North, S.J.1
Huang, H.-H.2
Sundaram, S.3
Jang-Lee, J.4
Etienne a, T.5
Trollope, A.6
Chalabi, S.7
Dell, A.8
Stanley, P.9
Haslam, S.M.10
-
38
-
-
84858983547
-
KEGG for integration and interpretation of large-scale molecular data sets
-
Kanehisa M., Goto S., Sato Y., Furumichi M., Tanabe M. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 2012, 40:D109-D114.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Kanehisa, M.1
Goto, S.2
Sato, Y.3
Furumichi, M.4
Tanabe, M.5
-
39
-
-
77954456926
-
Evaluation of extraction processes for intracellular metabolite profiling of mammalian cells: matching extraction approaches to cell type and metabolite targets
-
Sellick C.A., Knight D., Croxford A.S., Maqsood A.R., Stephens G.M., Goodacre R., Dickson A.J. Evaluation of extraction processes for intracellular metabolite profiling of mammalian cells: matching extraction approaches to cell type and metabolite targets. Metabolomics 2010, 6:427-438.
-
(2010)
Metabolomics
, vol.6
, pp. 427-438
-
-
Sellick, C.A.1
Knight, D.2
Croxford, A.S.3
Maqsood, A.R.4
Stephens, G.M.5
Goodacre, R.6
Dickson, A.J.7
-
40
-
-
84555189650
-
Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling
-
Sellick C.A., Hansen R., Stephens G.M., Goodacre R., Dickson A.J. Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling. Nat Protocol 2011, 6:1241-1249.
-
(2011)
Nat Protocol
, vol.6
, pp. 1241-1249
-
-
Sellick, C.A.1
Hansen, R.2
Stephens, G.M.3
Goodacre, R.4
Dickson, A.J.5
-
41
-
-
81155160851
-
Metabolite profiling of recombinant CHO cells: designing tailored feeding regimes that enhance recombinant antibody production
-
Sellick C.A., Croxford A.S., Maqsood A.R., Stephens G., Westerhoff H.V., Goodacre R., Dickson A.J. Metabolite profiling of recombinant CHO cells: designing tailored feeding regimes that enhance recombinant antibody production. Biotechnol Bioeng 2011, 108:3025-3031.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 3025-3031
-
-
Sellick, C.A.1
Croxford, A.S.2
Maqsood, A.R.3
Stephens, G.4
Westerhoff, H.V.5
Goodacre, R.6
Dickson, A.J.7
-
42
-
-
84859886034
-
Metabolite profiling of CHO cells with different growth characteristics
-
Dietmair S., Hodson M.P., Quek L.-E., Timmins N.E., Chrysanthopoulos P., Jacob S.S., Gray P., Nielsen L.K. Metabolite profiling of CHO cells with different growth characteristics. Biotechnol Bioeng 2012, 109:1404-1414.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1404-1414
-
-
Dietmair, S.1
Hodson, M.P.2
Quek, L.-E.3
Timmins, N.E.4
Chrysanthopoulos, P.5
Jacob, S.S.6
Gray, P.7
Nielsen, L.K.8
-
43
-
-
79960026499
-
Metabolomics profiling of cell culture media leading to the identification of riboflavin photosensitized degradation of tryptophan causing slow growth in cell culture
-
Zang L., Frenkel R., Simeone J., Lanan M., Byers M., Lyubarskaya Y. Metabolomics profiling of cell culture media leading to the identification of riboflavin photosensitized degradation of tryptophan causing slow growth in cell culture. Anal Chem 2011, 83:5422-5430.
-
(2011)
Anal Chem
, vol.83
, pp. 5422-5430
-
-
Zang, L.1
Frenkel, R.2
Simeone, J.3
Lanan, M.4
Byers, M.5
Lyubarskaya, Y.6
-
44
-
-
77952585767
-
Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II
-
Chong W.P.K., Reddy S.G., Yusufi F.N.K., Lee D.-Y., Wong N.S.C., Heng C.K., Yap M.G.S., Ho Y.S. Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II. J Biotechnol 2010, 147:116-121.
-
(2010)
J Biotechnol
, vol.147
, pp. 116-121
-
-
Chong, W.P.K.1
Reddy, S.G.2
Yusufi, F.N.K.3
Lee, D.-Y.4
Wong, N.S.C.5
Heng, C.K.6
Yap, M.G.S.7
Ho, Y.S.8
-
45
-
-
78651480501
-
Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media
-
Chong W.P.K., Yusufi F.N.K., Lee D.-Y., Reddy S.G., Wong N.S.C., Heng C.K., Yap M.G.S., Ho Y.S. Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media. J Biotechnol 2011, 151:218-224.
-
(2011)
J Biotechnol
, vol.151
, pp. 218-224
-
-
Chong, W.P.K.1
Yusufi, F.N.K.2
Lee, D.-Y.3
Reddy, S.G.4
Wong, N.S.C.5
Heng, C.K.6
Yap, M.G.S.7
Ho, Y.S.8
-
46
-
-
84868010172
-
LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells
-
Chong W.P.K., Thng S.H., Hiu A.P., Lee D.-Y., Chan E.C.Y., Ho Y.S. LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells. Biotechnol Bioeng 2012, 109:3103-3111.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 3103-3111
-
-
Chong, W.P.K.1
Thng, S.H.2
Hiu, A.P.3
Lee, D.-Y.4
Chan, E.C.Y.5
Ho, Y.S.6
-
47
-
-
76749097100
-
Metabolic flux analysis and pharmaceutical production
-
Boghigian B.A., Seth G., Kiss R., Pfeifer B.A. Metabolic flux analysis and pharmaceutical production. Metab Eng 2010, 12:81-95.
-
(2010)
Metab Eng
, vol.12
, pp. 81-95
-
-
Boghigian, B.A.1
Seth, G.2
Kiss, R.3
Pfeifer, B.A.4
-
48
-
-
84861008392
-
Rational design of 13C-labeling experiments for metabolic flux analysis in mammalian cells
-
Crown S.B., Ahn W.S., Antoniewicz M.R. Rational design of 13C-labeling experiments for metabolic flux analysis in mammalian cells. BMC Syst Biol 2012, 6:43.
-
(2012)
BMC Syst Biol
, vol.6
, pp. 43
-
-
Crown, S.B.1
Ahn, W.S.2
Antoniewicz, M.R.3
-
49
-
-
80052032471
-
Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry
-
Ahn W.S., Antoniewicz M.R. Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry. Metab Eng 2011, 13:598-609.
-
(2011)
Metab Eng
, vol.13
, pp. 598-609
-
-
Ahn, W.S.1
Antoniewicz, M.R.2
-
50
-
-
84858439602
-
Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods
-
Lewis N.E., Nagarajan H., Palsson B.O. Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. Nat Rev Microbiol 2012, 10:291-305.
-
(2012)
Nat Rev Microbiol
, vol.10
, pp. 291-305
-
-
Lewis, N.E.1
Nagarajan, H.2
Palsson, B.O.3
-
51
-
-
84872093417
-
Analysis of omics data with genome-scale models of metabolism
-
Hyduke D.R., Lewis N.E., Palsson B.Ø. Analysis of omics data with genome-scale models of metabolism. Mol Biosyst 2013, 9:167-174.
-
(2013)
Mol Biosyst
, vol.9
, pp. 167-174
-
-
Hyduke, D.R.1
Lewis, N.E.2
Palsson, B.Ø.3
-
52
-
-
78649447462
-
A detailed metabolic flux analysis of an underdetermined network of CHO cells
-
Zamorano F., Vande Wouwer A., Bastin G. A detailed metabolic flux analysis of an underdetermined network of CHO cells. J Biotechnol 2010, 150:497-508.
-
(2010)
J Biotechnol
, vol.150
, pp. 497-508
-
-
Zamorano, F.1
Vande Wouwer, A.2
Bastin, G.3
-
53
-
-
84871722305
-
Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption
-
Martínez V.S., Dietmair S., Quek L.-E., Hodson M.P., Gray P., Nielsen L.K. Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption. Biotechnol Bioeng 2012, 110:660-666.
-
(2012)
Biotechnol Bioeng
, vol.110
, pp. 660-666
-
-
Martínez, V.S.1
Dietmair, S.2
Quek, L.-E.3
Hodson, M.P.4
Gray, P.5
Nielsen, L.K.6
-
54
-
-
84862784156
-
Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture
-
Selvarasu S., Ho Y.S., Chong W.P.K., Wong N.S.C., Yusufi F.N.K., Lee Y.Y., Yap M.G.S., Lee D.-Y. Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture. Biotechnol Bioeng 2012, 109:1415-1429.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 1415-1429
-
-
Selvarasu, S.1
Ho, Y.S.2
Chong, W.P.K.3
Wong, N.S.C.4
Yusufi, F.N.K.5
Lee, Y.Y.6
Yap, M.G.S.7
Lee, D.-Y.8
-
55
-
-
84865296987
-
A multi-omics analysis of recombinant protein production in Hek293 cells
-
Dietmair S., Hodson M.P., Quek L.-E., Timmins N.E., Gray P., Nielsen L.K. A multi-omics analysis of recombinant protein production in Hek293 cells. PLoS One 2012, 7:e43394.
-
(2012)
PLoS One
, vol.7
-
-
Dietmair, S.1
Hodson, M.P.2
Quek, L.-E.3
Timmins, N.E.4
Gray, P.5
Nielsen, L.K.6
|