Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Kaas, Christian Schrøder ^a,b,c   Kristensen, Claus ^d   Betenbaugh, Michael J ^c   Andersen, Mikael Rørdam ^b  

^a NOVO NORDISK A S   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c Johns Hopkins University   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

C. griseus; CHO cells; CHO DXB11; Copy number variations (CNVs); Single nucleotide polymorphisms (SNPs)

Indexed keywords

DIHYDROFOLATE REDUCTASE; GENOMIC DNA;

ALLELE; ANIMAL CELL; ARTICLE; CHEMICAL MUTAGENESIS; CHINESE HAMSTER; CHO CELL LINE; CHO DXB11 CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; COPY NUMBER VARIATION; DHFR GENE; FEMALE; GENE DELETION; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC CODE; GENETIC VARIABILITY; GENOMIC INSTABILITY; HAPLOIDY; MISSENSE MUTATION; MOLECULAR EVOLUTION; NONHUMAN; PHYLOGENETIC TREE; POINT MUTATION; POLYPLOIDY; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION; ANIMAL; CHROMOSOME; CRICETULUS; DNA SEQUENCE; GENOME; HAMSTER;

CRICETULUS GRISEUS;

ANIMALS; CHO CELLS; CHROMOSOMES, MAMMALIAN; CRICETINAE; CRICETULUS; DNA COPY NUMBER VARIATIONS; GENETIC VARIATION; GENOME; GENOMIC INSTABILITY; HAPLOIDY; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYPLOIDY; SEQUENCE ANALYSIS, DNA;

EID: 84928740386     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1391-x     Document Type: Article

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