Pork as a source of omega-3 (n-3) fatty acids

Journal of Clinical Medicine

Volumn 4, Issue 12, 2015, Pages 1999-2011

  Dugan, Michael E R ^a   Vahmani, Payam ^a   Turner, Tyler D ^b   Mapiye, Cletos ^c   Juárez, Manuel ^a   Prieto, Nuria ^a   Beaulieu, Angela D ^d   Zijlstra, Ruurd T ^e   Patience, John F ^f   Aalhus, Jennifer L ^a  

^a LACOMBE RESEARCH CENTRE   (Canada)

^b HESS Timber GmbH and Co KG   (Germany)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d PRAIRIE SWINE CENTRE INC   (Canada)

^e UNIVERSITY OF ALBERTA   (Canada)

^f IOWA STATE UNIVERSITY   (United States)

Author keywords

DHA; EPA; ETA; LNA; n 3; Omega 3; Pig; Pork

Indexed keywords

DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID; LINOLENIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID;

HUMAN; META ANALYSIS (TOPIC); NONHUMAN; PORK; REVIEW;

EID: 84983559234     PISSN: None     EISSN: 20770383     Source Type: Journal    
DOI: 10.3390/jcm4121956     Document Type: Review

References (62)

1. Simopoulos, A. P. Importance of the omega-6/omega-3 balance in health and disease: Evolutionary aspects of diet. World Rev. Nutr. Diet. 2011, 102, 10-21. [PubMed]
2. FAO Sources of Meat. Available online: http://www. fao. org/ag/againfo/themes/en/meat/backgr_sources. html (accessed on 2 September 2015).
3. Ollis, T. E.; Meyer, B. J.; Howe, P. R. Australian food sources and intakes of omega-6 and omega-3 polyunsaturated fatty acids. Ann. Nutr. Metab. 1999, 43, 346-355. [CrossRef] [PubMed]
4. Teicholz, N. The Big Fat Surprise: Why Butter, Meat and Cheese belong in a Healthy Diet; Simon and Schuster: New York, NY, USA, 2014.
5. Fortin, A.; Robertson, W.; Tong, A. The eating quality of canadian pork and its relationship with intramuscular fat. Meat Sci. 2005, 69, 297-305. [CrossRef] [PubMed]
6. U. S. Department of Health and Human Services; U. S. Department of Agriculture. Dietary Guidelines for Americans; US Government Printing Office: Washington, DC, USA, 2010.
7. Siri-Tarino, P. W.; Sun, Q.; Hu, F. B.; Krauss, R. M. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am. J. Clin. Nutr. 2010, 98, 535-546. [CrossRef] [PubMed]
8. Chowdhury, R.; Warnakula, S.; Kunutsor, S.; Crowe, F.; Ward, H. A.; Johnson, L.; Franco, O. H.; Butterworth, A. S.; Forouhi, N. G.; Thompson, S. G.; et al. Association of dietary, circulating, and supplement fatty acids with coronary risk: A systematic review and meta-analysis. Ann. Intern. Med. 2014, 160, 398-406. [CrossRef] [PubMed]
9. Barendse, W. Should animal fats be back on the table? A critical review of the human health effects of animal fat. Anim. Prod. Sci. 2014, 54, 831-855.
10. Binnie, M. A.; Barlow, K.; Johnson, V.; Harrison, C. Red meats: Time for a paradigm shift in dietary advice. Meat Sci. 2014, 98, 445-451. [CrossRef] [PubMed]
11. Heinz, G.; Hautzinger, P. Meat Processing Technology for Small to Medium Scale Producers. Available online: http://www. fao. org/docrep/010/ai407e/ai407e00. htm (accessed on 2 September 2015).
12. Enser, M.; Hallett, K.; Hewitt, B.; Fursey, G. A. J.; Wood, J. D. Fatty acid content and composition of english beef, lamb and pork at retail. Meat Sci. 1996, 42, 443-456. [CrossRef]
13. Cardiovascular Review Group, Great Britain-Department of Health. Nutritional Aspects of Cardiovascular Disease; HMSO: Richmond, UK, 1994.
14. Juárez, M.; Dugan, M. E. R.; Aldai, N.; Aalhus, J. L.; Patience, J. F.; Zijlstra, R. T.; Beaulieu, A. D. Increasing omega-3 levels through dietary co-extruded flaxseed supplementation negatively affects pork palatability. Food Chem. 2011, 126, 1716-1723. [CrossRef] [PubMed]
15. Romans, J. R.; Johnson, R. C.; Wulf, D. M.; Libal, G. W.; Costello, W. J. Effects of ground flaxseed in swine diets on pig performance and on physical and sensory characteristics and omega-3 fatty acid content of pork: I. Dietary level of flaxseed. J. Anim. Sci. 1995, 73, 1982-1986.
16. Wood, J. D.; Enser, M.; Fisher, A. V.; Nute, G. R.; Sheard, P. R.; Richardson, R. I.; Hughes, S. I.; Whittington, F. M. Fat deposition, fatty acid composition and meat quality: A review. Meat Sci. 2008, 78, 343-358. [CrossRef] [PubMed]
17. Savell, J.; Cross, H. The role of fat in the palatability of beef, pork, and lamb. In Designing Foods: Animal Product Options in the Marketplace; National Academy Press: Washington, DC, USA, 1988; pp. 345-355.
18. Raes, K.; de Smet, S.; Demeyer, D. Effect of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat: A review. Anim. Feed Sci. Technol. 2004, 113, 199-221. [CrossRef]
19. Woods, V. B.; Fearon, A. M. Dietary sources of unsaturated fatty acids for animals and their transfer into meat, milk and eggs: A review. Livest. Sci. 2009, 126. [CrossRef]
20. Doreau, M.; Chilliard, Y. Digestion and metabolism of dietary fat in farm animals. Br. J. Nutr. 1997, 78, S15-S35. [CrossRef] [PubMed]
21. Shorland, F. B. Effect of the dietary fat on the composition of depot fats of animals. Nature 1950, 165. [CrossRef]
22. Turner, T. D.; Mapiye, C.; Aalhus, J. L.; Beaulieu, A. D.; Patience, J. F.; Zijlstra, R. T.; Dugan, M. E. R. Flaxseed fed pork: N-3 fatty acid enrichment and contribution to dietary recommendations. Meat Sci. 2014, 96, 541-547. [CrossRef] [PubMed]
23. Narayan, B.; Miyashita, K.; Hosakawa, M. Physiological effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)-A review. Food Rev. Int. 2006, 22, 291-307. [CrossRef]
24. Swanson, D.; Block, R.; Mousa, S. A. Omega-3 fatty acids EPA and DHA: Health benefits throughout life. Adv. Nutr. 2012, 3. [CrossRef] [PubMed]
25. Howe, P.; Meyer, B.; Record, S.; Baghurst, K. Dietary intake of long-chain omega-3 polyunsaturated fatty acids: Contribution of meat sources. Nutrition 2006, 22, 47-53. [CrossRef] [PubMed]
26. Miller, E.; Kaur, G.; Larsen, A.; Loh, S. P.; Linderborg, K.; Weisinger, H. S.; Turchini, G. M.; Cameron-Smith, D.; Sinclair, A. J. A short-term n-3 DPA supplementation study in humans. Eur. J. Nutr. 2013, 52, 895-904. [CrossRef] [PubMed]
27. Vahmani, P.; Mapiye, C.; Prieto, N.; Rolland, D. C.; McAllister, T. A.; Aalhus, J. L.; Dugan, M. E. The scope for manipulating the polyunsaturated fatty acid content of beef: A review. J. Anim. Sci. Biotechnol. 2015, 6. [CrossRef] [PubMed]
28. Canadian Food Inspection Agency (CFIA): Omega-3 and Omega-6 Polyunsaturated Fatty Acid Claims. Available online: http://www. inspection. gc. ca/food/labelling/food-labelling-for-industry/nutrient-content/specific-claim-requirements/eng/1389907770176/1389907817577?chap=7 (accessed on 9 September 2015).
29. Kris-Etherton, P. M. Monounsaturated fatty acids and risk of cardiovascular disease. Circulation 1999, 100, 1253-1258. [CrossRef] [PubMed]
30. Yu, S.; Derr, J.; Etherton, T. D.; Kris-Etherton, P. Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterolemic. Am. J. Clin. Nutr. 1995, 61, 1129-1139. [PubMed]
31. Koch, D. E.; Pearson, A. M.; Magee, W. T.; Hoefer, J. A.; Schweigert, B. S. Effect of diet on the fatty acid composition of pork fat. J. Anim. Sci. 1968, 27, 360-365.
32. Stewart, J. W.; Kaplan, M. L.; Beitz, D. C. Pork with a high content of polyunsaturated fatty acids lowers LDL cholesterol in women. Am. J. Clin. Nutr. 2001, 74, 179-187. [PubMed]
33. Anderson, D. B.; Kauffman, R. G.; Benevenga, N. J. Estimate of fatty acid turnover in porcine adipose tissue. Lipids 1972, 7, 488-489. [CrossRef] [PubMed]
34. Cunnane, S. C.; Stitt, P. A.; Sujata, G.; Armstrong, J. K. Raised omega-3 fatty acid levels in pigs fed flax. Can. J. Anim. Sci. 1990, 70, 251-254. [CrossRef]
35. Kouba, M.; Enser, M.; Whittington, F. M.; Nute, G. R.; Wood, J. D. Effect of a high-linolenic acid diet on lipogenic enzyme activities, fatty acid composition, and meat quality in the growing pig. J. Anim. Sci. 2003, 81, 1967-1979. [PubMed]
36. Corino, C.; Rossi, R.; Cannata, S.; Ratti, S. Effect of dietary linseed on the nutritional value and quality of pork and pork products: Systematic review and meta-analysis. Meat Sci. 2014, 98, 679-688. [CrossRef] [PubMed]
37. Cherian, G.; Sim, J. S. Dietary alpha-linolenic acid alters the fatty acid composition of lipid classes in swine tissues. J. Agric. Food Chem. 1995, 43, 2911-2916. [CrossRef]
38. Riley, P. A.; Enser, M.; Nute, G. R.; Wood, J. D. Effects of dietary linseed on nutritional value and other quality aspects of pig muscle and adipose tissue. Anim. Sci. 2000, 71, 483-500.
39. Ahn, D. U.; Lutz, S.; Sim, J. S. Effects of dietary alpha-linolenic acid on the fatty acid composition, storage stability and sensory characteristics of pork loin. Meat Sci. 1996, 43, 291-299. [CrossRef]
40. Romans, J. R.; Wulf, D. M.; Johnson, R. C.; Libal, G. W.; Costello, W. J. Effects of ground flaxseed in swine diets on pig performance and on physical and sensory characteristics and omega-3 fatty acid content of pork: II. Duration of 15% dietary flaxseed. J. Anim. Sci. 1995, 73, 1987-1999. [PubMed]
41. Juárez, M.; Dugan, M.; Aldai, N.; Aalhus, J.; Patience, J.; Zijlstra, R.; Beaulieu, A. Feeding co-extruded flaxseed to pigs: Effects of duration and feeding level on growth performance and backfat fatty acid composition of grower-finisher pigs. Meat Sci. 2010, 84, 578-584. [CrossRef] [PubMed]
42. Fontanillas, R.; Barroeta, A.; Baucells, M. D.; Guardiola, F. Backfat fatty acid evolution in swine fed diets high in either cis-monounsaturated, trans, or (n-3) fats. J. Anim. Sci. 1998, 76, 1045-1055. [PubMed]
43. Huang, F. R.; Zhan, Z. P.; Luo, J.; Liu, Z. X.; Peng, J. Duration of dietary linseed feeding affects the intramuscular fat, muscle mass and fatty acid composition in pig muscle. Livest. Sci. 2008, 118, 132-139. [CrossRef]
44. Martínez-Ramírez, H. R.; Kramer, J. K. G.; de Lange, C. F. M. Retention of n-3 polyunsaturated fatty acids in trimmed loin and belly is independent of timing of feeding ground flaxseed to growing-finishing female pigs. J. Anim. Sci. 2014, 92, 238-249. [CrossRef] [PubMed]
45. Enser, M.; Richardson, R. I.; Wood, J. D.; Gill, B. P.; Sheard, P. R. Feeding linseed to increase the n-3 pufa of pork: Fatty acid composition of muscle, adipose tissue, liver and sausages. Meat Sci. 2000, 55, 201-212. [CrossRef]
46. Nguyen, L. Q.; Nuijens, M. C. G. A.; Everts, H.; Salden, N.; Beynen, A. C. Mathematical relationships between the intake of n-6 and n-3 polyunsaturated fatty acids and their contents in adipose tissue of growing pigs. Meat Sci. 2003, 65, 1399-1406. [CrossRef]
47. Htoo, J. K.; Meng, X.; Patience, J. F.; Dugan, M. E. R.; Zijlstra, R. T. Effects of coextrusion of flaxseed and field pea on the digestibility of energy, ether extract, fatty acids, protein, and amino acids in grower-finisher pigs. J. Anim. Sci. 2008, 86, 2942-2951. [CrossRef] [PubMed]
48. U. S. Department of Health and Human Services (HHS). Food labeling: Nutrient content claims; alpha-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid omega-3 fatty acids. Fed. Regist. 2014, 79, 23262-23273.
49. European Food Safety Authority (EFSA). Scientific opinion: Labelling reference intake values for n-3 and n-6 polyunsaturated fatty acids. EPSA J. 2009, 1176, 1-11.
50. Kim, E. J.; Kim, M.-K.; Jin, X.-J.; Oh, J.-H.; Kim, J. E.; Chung, J. H. Skin aging and photoaging alter fatty acids composition, including 11, 14, 17-eicosatrienoic acid, in the epidermis of human skin. J. Korean Med. Sci. 2010, 25, 980-983. [CrossRef] [PubMed]
51. Schenck, P. A.; Rakoff, H.; Emken, E. A. 8 desaturation in vivo of deuterated eicosatrienoic acid by mouse liver. Lipids 1996, 31, 593-600. [CrossRef] [PubMed]
52. Coates, A. M.; Sioutis, S.; Buckley, J. D.; Howe, P. R. Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. Br. J. Nutr. 2009, 101, 592-597. [CrossRef] [PubMed]
53. Vossen, E.; Raes, K.; Maertens, L.; Vandenberge, V.; Haak, L.; Chiers, K.; Ducatelle, R.; de Smet, S. Diets containing n-3 fatty acids-enriched pork: Effect on blood lipids, oxidative status and atherosclerosis in rabbits. J. Food Biochem. 2012, 36, 359-368. [CrossRef]
54. Simopoulos, A. P. New products from the agri-food industry: The return of n-3 fatty acids into the food supply. Lipids 1999, 34, S297-S301. [CrossRef] [PubMed]
55. Lewis, N. M.; Seburg, S.; Flanagan, N. L. Enriched eggs as a source of n-3 polyunsaturated fatty acids for humans. Poult. Sci. 2000, 79, 971-974. [CrossRef] [PubMed]
56. Givens, D.; Gibbs, R. Very long chain n-3 polyunsaturated fatty acids in the food chain in the uk and the potential of animal-derived foods to increase intake. Nutr. Bull. 2006, 31, 104-110. [CrossRef]
57. Bryhni, E. A.; Kjos, N. P.; Ofstad, R.; Hunt, M. Polyunsaturated fat and fish oil in diets for growing-finishing pigs: Effects on fatty acid composition and meat, fat, and sausage quality. Meat Sci. 2002, 62. [CrossRef]
58. Damez, J.-L.; Clerjon, S. Quantifying and predicting meat and meat products quality attributes using electromagnetic waves: An overview. Meat Sci. 2013, 95, 879-896. [CrossRef] [PubMed]
59. Prieto, N.; Dugan, M. E. R.; López-Campos, O.; McAllister, T. A.; Aalhus, J. L.; Uttaro, B. Near infrared reflectance spectroscopy predicts the content of polyunsaturated fatty acids and biohydrogenation products in the subcutaneous fat of beef cows fed flaxseed. Meat Sci. 2012, 90, 43-51. [CrossRef] [PubMed]
60. Prieto, N.; Uttaro, B.; Mapiye, C.; Turner, T.; Dugan, M.; Zamora, V.; Young, M.; Beltranena, E. Predicting fat quality from pigs fed reduced-oil corn dried distillers grains with solubles by near infrared reflectance spectroscopy: Fatty acid composition and iodine value. Meat Sci. 2014, 98, 585-590. [CrossRef] [PubMed]
61. Berhe, D. T.; Eskildsen, C. E.; Lametsch, R.; Hviid, M. S.; van den Berg, F.; Engelsen, S. B. Prediction of total fatty acid parameters and individual fatty acids in pork backfat using raman spectroscopy and chemometrics: Understanding the cage of covariance between highly correlated fat parameters. Meat Sci. 2016, 111, 18-26. [CrossRef] [PubMed]
62. Cecchini, M.; Sassi, F.; Lauer, J. A.; Lee, Y. Y.; Guajardo-Barron, V.; Chisholm, D. Tackling of unhealthy diets, physical inactivity, and obesity: Health effects and cost-effectiveness. Lancet 2010, 376, 1775-1784. [CrossRef]