Skin aging and photoaging alter fatty acids composition, including 11,14,17-eicosatrienoic acid, in the epidermis of human skin

Journal of Korean Medical Science

Volumn 25, Issue 6, 2010, Pages 980-983

  Kim, Eun Ju ^a   Kim, Min Kyoung ^a   Jin, Xing Ji ^a   Oh, Jang Hee ^a   Kim, Ji Eun ^a   Chung, Jin Ho ^a  

^a Seoul National University Hospital   (South Korea)

Author keywords

11,14,17 eicosatrienoic acid; Calcium Independent; Fatty acids; Human Elongase 1; Nonesterified; Omega 3; Phospholipases A2; Ultraviolet rays

Indexed keywords

11,14,17 ICOSATRIENOIC ACID; 11,14,17-EICOSATRIENOIC ACID; ACYLTRANSFERASE; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; DIHOMO GAMMA LINOLENIC ACID; EPTC; FATTY ACID; FATTY ACID ELONGASES; INTERSTITIAL COLLAGENASE; THIOCARBAMIC ACID DERIVATIVE;

ADULT; AGED; ARTICLE; CELL LINE; CHEMISTRY; CUTANEOUS PARAMETERS; DRUG ANTAGONISM; EPIDERMIS; HUMAN; KERATINOCYTE; METABOLISM; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

8,11,14-EICOSATRIENOIC ACID; ACETYLTRANSFERASES; ADULT; AGED; CELL LINE; EPIDERMIS; FATTY ACIDS; HUMANS; KERATINOCYTES; MATRIX METALLOPROTEINASE 1; PHOSPHOLIPASES A2, CALCIUM-INDEPENDENT; SKIN AGING; THIOCARBAMATES; ULTRAVIOLET RAYS; YOUNG ADULT;

EID: 77956398976     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2010.25.6.980     Document Type: Article

References (12)

1. Jenkins G. Molecular mechanisms of skin ageing. Mech Ageing Dev 2002; 123: 801-10.
2. Fisher GJ, Kang S, Varani J, Bata-Csorgo Z, Wan Y, Datta S, Voorhees JJ. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 2002; 138: 1462-70.
3. Trommer H, Wagner J, Graener H, Neubert RH. The examination of skin lipid model systems stressed by ultraviolet irradiation in the presence of transition metal ions. Eur J Pharm Biopharm 2001; 51: 207-14.
4. Hansen HS, Jensen B. Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. Biochim Biophys Acta 1985; 834: 357-63.
5. Jump DB. Fatty acid regulation of gene transcription. Crit Rev Clin Lab Sci 2004; 41: 41-78.
6. Siddiqui RA, Harvey KA, Zaloga GP. Modulation of enzymatic activities by n-3 polyunsaturated fatty acids to support cardiovascular health. J Nutr Biochem 2008; 19: 417-37.
7. Jakobsson A, Westerberg R, Jacobsson A. Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog Lipid Res 2006; 45: 237-49.
8. Leonard AE, Bobik EG, Dorado J, Kroeger PE, Chuang LT, Thurmond JM, Parker-Barnes JM, Das T, Huang YS, Mukerji P. Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids. Biochem J 2000; 350 Pt 3: 765-70.
9. Strokin M, Sergeeva M, Reiser G. Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+. Br J Pharmacol 2003; 139: 1014-22.
10. Daviglus ML, Stamler J, Orencia AJ, Dyer AR, Liu K, Greenland P, Walsh MK, Morris D, Shekelle RB. Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med 1997; 336: 1046-53.
11. Kushi L, Giovannucci E. Dietary fat and cancer. Am J Med 2002; 113 Suppl 9B: 63S-70.
12. Horrobin DF, Bennett CN. Depression and bipolar disorder: relationships to impaired fatty acid and phospholipid metabolism and to diabetes, cardiovascular disease, immunological abnormalities, cancer, ageing and osteoporosis. Possible candidate genes. Prostaglandins Leukot Essent Fatty Acids 1999; 60: 217-34