-
1
-
-
84906243997
-
The self-obsession of T cells: how TCR signaling thresholds affect fate ‘decisions’ and effector function
-
1 Hogquist, K.A., Jameson, S.C., The self-obsession of T cells: how TCR signaling thresholds affect fate ‘decisions’ and effector function. Nat. Immunol. 15 (2014), 815–823.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 815-823
-
-
Hogquist, K.A.1
Jameson, S.C.2
-
2
-
-
84901487911
-
Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)
-
2 Klein, L., et al. Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see). Nat. Rev. Immunol. 14 (2014), 377–391.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 377-391
-
-
Klein, L.1
-
3
-
-
84859388345
-
Selection of self-reactive T cells in the thymus
-
3 Stritesky, G.L., et al. Selection of self-reactive T cells in the thymus. Annu. Rev. Immunol. 30 (2012), 95–114.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 95-114
-
-
Stritesky, G.L.1
-
4
-
-
74049160009
-
Mechanisms maintaining peripheral tolerance
-
4 Mueller, D.L., Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11 (2010), 21–27.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 21-27
-
-
Mueller, D.L.1
-
5
-
-
0025370870
-
T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
-
5 Ota, K., et al. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346 (1990), 183–187.
-
(1990)
Nature
, vol.346
, pp. 183-187
-
-
Ota, K.1
-
6
-
-
84930408029
-
Mechanisms of human autoimmunity
-
6 Rosenblum, M.D., et al. Mechanisms of human autoimmunity. J. Clin. Invest. 125 (2015), 2228–2233.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 2228-2233
-
-
Rosenblum, M.D.1
-
7
-
-
84908072032
-
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
-
7 Ito, Y., et al. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science 346 (2014), 363–368.
-
(2014)
Science
, vol.346
, pp. 363-368
-
-
Ito, Y.1
-
8
-
-
84919665688
-
+ T cells with an anergic phenotype in healthy individuals
-
+ T cells with an anergic phenotype in healthy individuals. Science 346 (2014), 1536–1540.
-
(2014)
Science
, vol.346
, pp. 1536-1540
-
-
Maeda, Y.1
-
9
-
-
84929676377
-
+ T lymphocytes
-
+ T lymphocytes. Immunity 42 (2015), 929–941.
-
(2015)
Immunity
, vol.42
, pp. 929-941
-
-
Yu, W.1
-
10
-
-
84874253445
-
+ memory-phenotype T cells are abundant in unexposed adults
-
+ memory-phenotype T cells are abundant in unexposed adults. Immunity 38 (2013), 373–383.
-
(2013)
Immunity
, vol.38
, pp. 373-383
-
-
Su, L.F.1
-
11
-
-
84860346184
-
The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude
-
11 Jenkins, M.K., Moon, J.J., The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. J. Immunol. 188 (2012), 4135–4140.
-
(2012)
J. Immunol.
, vol.188
, pp. 4135-4140
-
-
Jenkins, M.K.1
Moon, J.J.2
-
12
-
-
65549087573
-
+ T cell precursor frequency determines the quality of the antitumor immune response
-
+ T cell precursor frequency determines the quality of the antitumor immune response. J. Exp. Med. 206 (2009), 849–866.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 849-866
-
-
Rizzuto, G.A.1
-
13
-
-
34548038390
-
+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude
-
+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 27 (2007), 203–213.
-
(2007)
Immunity
, vol.27
, pp. 203-213
-
-
Moon, J.J.1
-
14
-
-
78449298644
-
CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire
-
14 de Jong, A., et al. CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire. Nat. Immunol. 11 (2010), 1102–1109.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 1102-1109
-
-
de Jong, A.1
-
15
-
-
79951796594
-
High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells
-
15 de Lalla, C., et al. High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells. Eur. J. Immunol. 41 (2011), 602–610.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 602-610
-
-
de Lalla, C.1
-
16
-
-
84870266508
-
Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen
-
16 Taylor, J.J., et al. Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen. J. Exp. Med. 209 (2012), 2065–2077.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2065-2077
-
-
Taylor, J.J.1
-
17
-
-
56349161598
-
B-cell tolerance checkpoints in health and autoimmunity
-
17 Meffre, E., Wardemann, H., B-cell tolerance checkpoints in health and autoimmunity. Curr. Opin. Immunol. 20 (2008), 632–638.
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 632-638
-
-
Meffre, E.1
Wardemann, H.2
-
18
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
18 Kim, J.M., et al. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8 (2007), 191–197.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
-
19
-
-
84920976294
-
+ T-cell responses
-
+ T-cell responses. Eur. J. Immunol. 44 (2014), 3621–3631.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 3621-3631
-
-
Nystrom, S.N.1
-
20
-
-
84940121598
-
The contained self-reactive peripheral T cell repertoire: size, diversity, and cellular composition
-
20 Richards, D.M., et al. The contained self-reactive peripheral T cell repertoire: size, diversity, and cellular composition. J. Immunol. 195 (2015), 2067–2079.
-
(2015)
J. Immunol.
, vol.195
, pp. 2067-2079
-
-
Richards, D.M.1
-
21
-
-
0035863825
-
Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question
-
21 Suchin, E.J., et al. Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question. J. Immunol. 166 (2001), 973–981.
-
(2001)
J. Immunol.
, vol.166
, pp. 973-981
-
-
Suchin, E.J.1
-
22
-
-
0033008083
-
The structural basis of T cell activation by superantigens
-
22 Li, H.M., et al. The structural basis of T cell activation by superantigens. Annu. Rev. Immunol. 17 (1999), 435–466.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 435-466
-
-
Li, H.M.1
-
23
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
23 Waterhouse, P., et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270 (1995), 985–988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
-
24
-
-
33748465396
-
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-β receptor
-
24 Marie, J.C., et al. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-β receptor. Immunity 25 (2006), 441–454.
-
(2006)
Immunity
, vol.25
, pp. 441-454
-
-
Marie, J.C.1
-
25
-
-
84947441287
-
+ T cell tolerance to tissue-restricted self-antigens is mediated by antigen-specific regulatory T cells rather than deletion
-
+ T cell tolerance to tissue-restricted self-antigens is mediated by antigen-specific regulatory T cells rather than deletion. Immunity 43 (2015), 896–908.
-
(2015)
Immunity
, vol.43
, pp. 896-908
-
-
Legoux, F.P.1
-
26
-
-
33747092627
-
T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity
-
26 Zehn, D., Bevan, M.J., T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity. Immunity 25 (2006), 261–270.
-
(2006)
Immunity
, vol.25
, pp. 261-270
-
-
Zehn, D.1
Bevan, M.J.2
-
28
-
-
84870280593
-
Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection
-
28 Enouz, S., et al. Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection. J. Exp. Med. 209 (2012), 1769–1779.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1769-1779
-
-
Enouz, S.1
-
29
-
-
84867777146
-
+ T cells specifically regulate the frequency of individual antigen-reactive T cells
-
+ T cells specifically regulate the frequency of individual antigen-reactive T cells. Immunity 37 (2012), 735–746.
-
(2012)
Immunity
, vol.37
, pp. 735-746
-
-
Singh, N.J.1
-
30
-
-
84921278229
-
T cell receptor cross-reactivity between similar foreign and self-peptides influences naive cell population size and autoimmunity
-
30 Nelson, R.W., et al. T cell receptor cross-reactivity between similar foreign and self-peptides influences naive cell population size and autoimmunity. Immunity 42 (2015), 95–107.
-
(2015)
Immunity
, vol.42
, pp. 95-107
-
-
Nelson, R.W.1
-
31
-
-
84901295133
-
Deconstructing the peptide-MHC specificity of T cell recognition
-
31 Birnbaum, M.E., et al. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 157 (2014), 1073–1087.
-
(2014)
Cell
, vol.157
, pp. 1073-1087
-
-
Birnbaum, M.E.1
-
32
-
-
84924610426
-
+ T cells
-
+ T cells. J. Immunol. 194 (2015), 2531–2538.
-
(2015)
J. Immunol.
, vol.194
, pp. 2531-2538
-
-
Eugster, A.1
-
33
-
-
84855497162
-
A single autoimmune T cell receptor recognizes more than a million different peptides
-
33 Wooldridge, L., et al. A single autoimmune T cell receptor recognizes more than a million different peptides. J. Biol. Chem. 287 (2012), 1168–1177.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 1168-1177
-
-
Wooldridge, L.1
-
34
-
-
84947444776
-
Crossreactive αβ T cell receptors are the predominant targets of thymocyte negative selection
-
34 McDonald, B.D., et al. Crossreactive αβ T cell receptors are the predominant targets of thymocyte negative selection. Immunity 43 (2015), 859–869.
-
(2015)
Immunity
, vol.43
, pp. 859-869
-
-
McDonald, B.D.1
-
35
-
-
84927652023
-
Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function
-
35 Grossman, Z., Paul, W.E., Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function. Annu. Rev. Immunol. 33 (2015), 677–713.
-
(2015)
Annu. Rev. Immunol.
, vol.33
, pp. 677-713
-
-
Grossman, Z.1
Paul, W.E.2
-
36
-
-
0034889233
-
+ T cells without selection of higher affinity TCR
-
+ T cells without selection of higher affinity TCR. Nat. Immunol. 2 (2001), 711–717.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 711-717
-
-
Slifka, M.K.1
Whitton, J.L.2
-
37
-
-
84894447120
-
+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self-peptide and MHC
-
+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self-peptide and MHC. Nat. Immunol. 15 (2014), 266–274.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 266-274
-
-
Persaud, S.P.1
-
38
-
-
84874244135
-
T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens
-
38 Mandl, J.N., et al. T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens. Immunity 38 (2013), 263–274.
-
(2013)
Immunity
, vol.38
, pp. 263-274
-
-
Mandl, J.N.1
-
39
-
-
84924979971
-
+ T cells to respond to foreign antigens
-
+ T cells to respond to foreign antigens. Nat. Immunol. 16 (2015), 107–117.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 107-117
-
-
Fulton, R.B.1
-
40
-
-
84915747866
-
Optimal T-cell receptor affinity for inducing autoimmunity
-
40 Koehli, S., et al. Optimal T-cell receptor affinity for inducing autoimmunity. Proc. Natl. Acad. Sci. U.S.A. 111 (2014), 17248–17253.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 17248-17253
-
-
Koehli, S.1
-
41
-
-
84924988088
-
CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens
-
41 Henderson, J.G., et al. CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens. Immunity 42 (2015), 471–483.
-
(2015)
Immunity
, vol.42
, pp. 471-483
-
-
Henderson, J.G.1
-
42
-
-
79958251745
-
T cell receptor signal strength in T-reg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
-
42 Moran, A.E., et al. T cell receptor signal strength in T-reg and iNKT cell development demonstrated by a novel fluorescent reporter mouse. J. Exp. Med. 208 (2011), 1279–1289.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1279-1289
-
-
Moran, A.E.1
-
43
-
-
84875257845
-
Murine thymic selection quantified using a unique method to capture deleted T cells
-
43 Stritesky, G.L., et al. Murine thymic selection quantified using a unique method to capture deleted T cells. Proc. Natl. Acad. Sci. U.S.A. 110 (2013), 4679–4684.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 4679-4684
-
-
Stritesky, G.L.1
-
44
-
-
84907228126
-
A sharp T-cell antigen receptor signaling threshold for T-cell proliferation
-
44 Au-Yeung, B.B., et al. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 111 (2014), E3679–E3688.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. E3679-E3688
-
-
Au-Yeung, B.B.1
-
45
-
-
58749109022
-
Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire
-
45 Wolfl, M., et al. Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire. J. Immunol. 181 (2008), 6435–6446.
-
(2008)
J. Immunol.
, vol.181
, pp. 6435-6446
-
-
Wolfl, M.1
-
46
-
-
0037191792
-
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
-
46 Stefanova, I., et al. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 420 (2002), 429–434.
-
(2002)
Nature
, vol.420
, pp. 429-434
-
-
Stefanova, I.1
-
47
-
-
34247118771
-
Molecular mimicry and auto-immunity
-
47 Blank, M., et al. Molecular mimicry and auto-immunity. Clin. Rev. Allergy Immunol. 32 (2007), 111–118.
-
(2007)
Clin. Rev. Allergy Immunol.
, vol.32
, pp. 111-118
-
-
Blank, M.1
-
48
-
-
84940930030
-
Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site
-
48 Horai, R., et al. Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site. Immunity 43 (2015), 343–353.
-
(2015)
Immunity
, vol.43
, pp. 343-353
-
-
Horai, R.1
-
49
-
-
84885063645
-
CNS-specific T cells shape brain function via the choroid plexus
-
49 Baruch, K., Schwartz, M., CNS-specific T cells shape brain function via the choroid plexus. Brain Behav. Immun. 34 (2013), 11–16.
-
(2013)
Brain Behav. Immun.
, vol.34
, pp. 11-16
-
-
Baruch, K.1
Schwartz, M.2
-
50
-
-
84866391516
-
Pro-cognitive properties of T cells
-
50 Kipnis, J., et al. Pro-cognitive properties of T cells. Nat. Rev. Immunol. 12 (2012), 662–668.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 662-668
-
-
Kipnis, J.1
-
51
-
-
84904301649
-
Protective autoimmunity: a unifying model for the immune network involved in CNS repair
-
51 Schwartz, M., Raposo, C., Protective autoimmunity: a unifying model for the immune network involved in CNS repair. Neuroscientist 20 (2014), 343–358.
-
(2014)
Neuroscientist
, vol.20
, pp. 343-358
-
-
Schwartz, M.1
Raposo, C.2
-
52
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
52 Moalem, G., et al. Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat. Med. 5 (1999), 49–55.
-
(1999)
Nat. Med.
, vol.5
, pp. 49-55
-
-
Moalem, G.1
-
53
-
-
0025246367
-
The T lymphocyte in experimental allergic encephalomyelitis
-
53 Zamvil, S.S., Steinman, L., The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8 (1990), 579–621.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 579-621
-
-
Zamvil, S.S.1
Steinman, L.2
-
54
-
-
13544261413
-
+ T cells
-
+ T cells. Blood 105 (2005), 1484–1491.
-
(2005)
Blood
, vol.105
, pp. 1484-1491
-
-
Monteiro, J.P.1
-
55
-
-
65549105119
-
A role for human skin-resident T cells in wound healing
-
55 Toulon, A., et al. A role for human skin-resident T cells in wound healing. J. Exp. Med. 206 (2009), 743–750.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 743-750
-
-
Toulon, A.1
-
56
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
56 Feuerer, M., et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat. Med. 15 (2009), 930–939.
-
(2009)
Nat. Med.
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
-
57
-
-
84862986986
-
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
57 Cipolletta, D., et al. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 486 (2012), 549–553.
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
-
58
-
-
84890050252
-
A special population of regulatory T cells potentiates muscle repair
-
58 Burzyn, D., et al. A special population of regulatory T cells potentiates muscle repair. Cell 155 (2013), 1282–1295.
-
(2013)
Cell
, vol.155
, pp. 1282-1295
-
-
Burzyn, D.1
-
59
-
-
84940380928
-
A distinct function of regulatory T cells in tissue protection
-
59 Arpaia, N., et al. A distinct function of regulatory T cells in tissue protection. Cell 162 (2015), 1078–1089.
-
(2015)
Cell
, vol.162
, pp. 1078-1089
-
-
Arpaia, N.1
-
60
-
-
51149085208
-
Nature and functions of autoantibodies
-
60 Elkon, K., Casali, P., Nature and functions of autoantibodies. Nat. Clin. Pract. Rheumatol. 4 (2008), 491–498.
-
(2008)
Nat. Clin. Pract. Rheumatol.
, vol.4
, pp. 491-498
-
-
Elkon, K.1
Casali, P.2
-
61
-
-
84856568116
-
Natural IgM in immune equilibrium and harnessing their therapeutic potential
-
61 Kaveri, S.V., et al. Natural IgM in immune equilibrium and harnessing their therapeutic potential. J. Immunol. 188 (2012), 939–945.
-
(2012)
J. Immunol.
, vol.188
, pp. 939-945
-
-
Kaveri, S.V.1
-
62
-
-
84862814979
-
Selection of regulatory T cells in the thymus
-
62 Hsieh, C.S., et al. Selection of regulatory T cells in the thymus. Nat. Rev. Immunol. 12 (2012), 157–167.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 157-167
-
-
Hsieh, C.S.1
-
63
-
-
84907982768
-
Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus
-
63 Perry, J.S., et al. Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus. Immunity 41 (2014), 414–426.
-
(2014)
Immunity
, vol.41
, pp. 414-426
-
-
Perry, J.S.1
-
64
-
-
36749031198
-
+ regulatory T cells in the NOD mouse model of autoimmune diabetes
-
+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proc. Natl. Acad. Sci. U.S.A. 104 (2007), 18181–18186.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 18181-18186
-
-
Feuerer, M.1
-
65
-
-
84869148187
-
T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development
-
65 Ohkura, N., et al. T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development. Immunity 37 (2012), 785–799.
-
(2012)
Immunity
, vol.37
, pp. 785-799
-
-
Ohkura, N.1
-
66
-
-
84921729777
-
Transcriptional control of regulatory T cells
-
66 Delacher, M., et al. Transcriptional control of regulatory T cells. Curr. Top. Microbiol. Immunol. 381 (2014), 83–124.
-
(2014)
Curr. Top. Microbiol. Immunol.
, vol.381
, pp. 83-124
-
-
Delacher, M.1
-
67
-
-
84928581675
-
Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
-
67 Yang, S., et al. Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance. Science 348 (2015), 589–594.
-
(2015)
Science
, vol.348
, pp. 589-594
-
-
Yang, S.1
-
68
-
-
84947441940
-
A wave of regulatory T cells into neonatal skin mediates tolerance to commensal microbes
-
68 Scharschmidt, T.C., et al. A wave of regulatory T cells into neonatal skin mediates tolerance to commensal microbes. Immunity 43 (2015), 1011–1021.
-
(2015)
Immunity
, vol.43
, pp. 1011-1021
-
-
Scharschmidt, T.C.1
-
69
-
-
84928407438
-
Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice
-
69 Kolodin, D., et al. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metab. 21 (2015), 543–557.
-
(2015)
Cell Metab.
, vol.21
, pp. 543-557
-
-
Kolodin, D.1
-
70
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
70 Hodi, F.S., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363 (2010), 711–723.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
-
71
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
71 Topalian, S.L., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366 (2012), 2443–2454.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
-
72
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
72 Wolchok, J.D., et al. Nivolumab plus ipilimumab in advanced melanoma. N. Engl. J. Med. 369 (2013), 122–133.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
-
73
-
-
84928759208
-
Adoptive cell transfer as personalized immunotherapy for human cancer
-
73 Rosenberg, S.A., Restifo, N.P., Adoptive cell transfer as personalized immunotherapy for human cancer. Science 348 (2015), 62–68.
-
(2015)
Science
, vol.348
, pp. 62-68
-
-
Rosenberg, S.A.1
Restifo, N.P.2
-
74
-
-
84937846973
-
Evolving synergistic combinations of targeted immunotherapies to combat cancer
-
74 Melero, I., et al. Evolving synergistic combinations of targeted immunotherapies to combat cancer. Nat. Rev. Cancer 15 (2015), 457–472.
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 457-472
-
-
Melero, I.1
-
75
-
-
84927130807
-
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential
-
75 Sharma, P., Allison, J.P., Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential. Cell 161 (2015), 205–214.
-
(2015)
Cell
, vol.161
, pp. 205-214
-
-
Sharma, P.1
Allison, J.P.2
-
76
-
-
84941343279
-
Releasing the brakes on cancer immunotherapy
-
76 Littman, D.R., Releasing the brakes on cancer immunotherapy. Cell 162 (2015), 1186–1190.
-
(2015)
Cell
, vol.162
, pp. 1186-1190
-
-
Littman, D.R.1
-
77
-
-
84957836940
-
Immune response to cancer therapy: mounting an effective antitumor response and mechanisms of resistance
-
77 Medler, T.R., et al. Immune response to cancer therapy: mounting an effective antitumor response and mechanisms of resistance. Trends Cancer 1 (2015), 66–75.
-
(2015)
Trends Cancer
, vol.1
, pp. 66-75
-
-
Medler, T.R.1
-
78
-
-
84905503399
-
Opportunistic autoimmune disorders potentiated by immune-checkpoint inhibitors anti-CTLA-4 and anti-PD-1
-
78 Kong, Y.C., Flynn, J.C., Opportunistic autoimmune disorders potentiated by immune-checkpoint inhibitors anti-CTLA-4 and anti-PD-1. Front. Immunol., 5, 2014, 206.
-
(2014)
Front. Immunol.
, vol.5
, pp. 206
-
-
Kong, Y.C.1
Flynn, J.C.2
-
79
-
-
84859416933
-
Regulatory T cells: mechanisms of differentiation and function
-
79 Josefowicz, S.Z., et al. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30 (2012), 531–564.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
-
80
-
-
84928591321
-
The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases
-
80 Klatzmann, D., Abbas, A.K., The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases. Nat. Rev. Immunol. 15 (2015), 283–294.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 283-294
-
-
Klatzmann, D.1
Abbas, A.K.2
|