-
1
-
-
75749141271
-
Opportunistic autoimmune disorders: from immunotherapy to immune dysregulation
-
doi: 10.1111/j.1749-6632.2009.05138.x
-
Kong YM, Wei W-Z, Tomer Y. Opportunistic autoimmune disorders: from immunotherapy to immune dysregulation. Ann N Y Acad Sci (2010) 1183:222-36. doi: 10.1111/j.1749-6632.2009.05138.x
-
(2010)
Ann N Y Acad Sci
, vol.1183
, pp. 222-236
-
-
Kong, Y.M.1
Wei, W.-Z.2
Tomer, Y.3
-
2
-
-
79960657821
-
Autoimmunity associated with immunotherapy of cancer
-
doi:10.1182/blood-2011-01-325266
-
Amos SM, Duong CP, Westwood JA, Ritchie DS, Junghans RP, Darcy PK, et al. Autoimmunity associated with immunotherapy of cancer. Blood (2011) 118:499-509. doi:10.1182/blood-2011-01-325266
-
(2011)
Blood
, vol.118
, pp. 499-509
-
-
Amos, S.M.1
Duong, C.P.2
Westwood, J.A.3
Ritchie, D.S.4
Junghans, R.P.5
Darcy, P.K.6
-
3
-
-
80655149496
-
Thyroid dysfunction from antineoplastic agents
-
doi:10.1093/jnci/djr373
-
Hamnvik OP, Larsen PR, Marqusee E. Thyroid dysfunction from antineoplastic agents. J Natl Cancer Inst (2011) 103:1572-87. doi:10.1093/jnci/djr373
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1572-1587
-
-
Hamnvik, O.P.1
Larsen, P.R.2
Marqusee, E.3
-
4
-
-
84880511594
-
Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma
-
doi:10.1111/nyas.12180
-
Wolchok JD, Hodi FS, Weber JS, Allison JP, Urba WJ, Robert C, et al. Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma. Ann N Y Acad Sci (2013) 1291:1-13. doi:10.1111/nyas.12180
-
(2013)
Ann N Y Acad Sci
, vol.1291
, pp. 1-13
-
-
Wolchok, J.D.1
Hodi, F.S.2
Weber, J.S.3
Allison, J.P.4
Urba, W.J.5
Robert, C.6
-
6
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
doi:10.1200/JCO.2012.44.6112
-
Ribas A, Kefford R, Marshall MA, Punt CJ, Haanen JB, Marmol M, et al. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol (2013) 31:616-22. doi:10.1200/JCO.2012.44.6112
-
(2013)
J Clin Oncol
, vol.31
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
-
8
-
-
33744792341
-
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
-
doi:10.1200/jco.2005.04.5716
-
Beck KE, Blansfield JA, Tran KQ, Feldman AL, Hughes MS, Royal RE, et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol (2006) 24:2283-9. doi:10.1200/jco.2005.04.5716
-
(2006)
J Clin Oncol
, vol.24
, pp. 2283-2289
-
-
Beck, K.E.1
Blansfield, J.A.2
Tran, K.Q.3
Feldman, A.L.4
Hughes, M.S.5
Royal, R.E.6
-
9
-
-
0029120245
-
4 have opposing effects on the response of T cells to stimulation
-
doi:10.1084/jem.182.2.459
-
4 have opposing effects on the response of T cells to stimulation. J Exp Med (1995) 182:459-65. doi:10.1084/jem.182.2.459
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
13
-
-
0028867420
-
4
-
doi:10.1016/1074-7613(95)90125-6
-
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity (1995) 3:541-7. doi:10.1016/1074-7613(95)90125-6
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
14
-
-
71649114308
-
Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function
-
doi:10.1016/j.jaut.2009.09.004
-
Kong YM, Morris GP, Brown NK, Yan Y, Flynn JC, David CS. Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function. J Autoimmun (2009) 33:239-46. doi:10.1016/j.jaut.2009.09.004
-
(2009)
J Autoimmun
, vol.33
, pp. 239-246
-
-
Kong, Y.M.1
Morris, G.P.2
Brown, N.K.3
Yan, Y.4
Flynn, J.C.5
David, C.S.6
-
15
-
-
67349151620
-
+ regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen
-
doi:10.1016/j.jaut.2009.03.010
-
+ regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen. J Autoimmun (2009) 33:68-76. doi:10.1016/j.jaut.2009.03.010
-
(2009)
J Autoimmun
, vol.33
, pp. 68-76
-
-
Morris, G.P.1
Brown, N.K.2
Kong, Y.M.3
-
16
-
-
77957273591
-
Improved endpoints for cancer immunotherapy trials
-
doi:10.1093/jnci/djq310
-
Hoos A, Eggermont AM, Janetzki S, Hodi FS, Ibrahim R, Anderson A, et al. Improved endpoints for cancer immunotherapy trials. J Natl Cancer Inst (2010) 102:1388-97. doi:10.1093/jnci/djq310
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 1388-1397
-
-
Hoos, A.1
Eggermont, A.M.2
Janetzki, S.3
Hodi, F.S.4
Ibrahim, R.5
Anderson, A.6
-
17
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
doi:10.1200/JCO.2012.41.6750
-
Weber JS, Kahler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol (2012) 30:2691-7. doi:10.1200/JCO.2012.41.6750
-
(2012)
J Clin Oncol
, vol.30
, pp. 2691-2697
-
-
Weber, J.S.1
Kahler, K.C.2
Hauschild, A.3
-
18
-
-
0031240055
-
Epidemiology and estimated population burden of selected autoimmune diseases in the United States
-
doi:10.1006/clin.1997.4412
-
Jacobson DL, Gange SJ, Rose NR, Graham NMH. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol (1997) 84:223-43. doi:10.1006/clin.1997.4412
-
(1997)
Clin Immunol Immunopathol
, vol.84
, pp. 223-243
-
-
Jacobson, D.L.1
Gange, S.J.2
Rose, N.R.3
Graham, N.M.H.4
-
19
-
-
84860135451
-
Hypophysitis induced by monoclonal antibodies to cytotoxic T lymphocyte antigen 4: challenges from a new cause of a rare disease
-
doi:10.1634/theoncologist.2011-0404
-
Torino F, Barnabei A, De VL, Salvatori R, Corsello SM. Hypophysitis induced by monoclonal antibodies to cytotoxic T lymphocyte antigen 4: challenges from a new cause of a rare disease. Oncologist (2012) 17:525-35. doi:10.1634/theoncologist.2011-0404
-
(2012)
Oncologist
, vol.17
, pp. 525-535
-
-
Torino, F.1
Barnabei, A.2
De, V.L.3
Salvatori, R.4
Corsello, S.M.5
-
20
-
-
84876248304
-
Endocrine side effects induced by immune checkpoint inhibitors
-
doi:10.1210/jc.2012-4075
-
Corsello SM, Barnabei A, Marchetti P, De VL, Salvatori R, Torino F. Endocrine side effects induced by immune checkpoint inhibitors. J Clin Endocrinol Metab (2013) 98:1361-75. doi:10.1210/jc.2012-4075
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 1361-1375
-
-
Corsello, S.M.1
Barnabei, A.2
Marchetti, P.3
De, V.L.4
Salvatori, R.5
Torino, F.6
-
21
-
-
0020023526
-
Tolerance to thyroglobulin by activating suppressor mechanisms
-
doi:10.1111/j.1749-6632.1982.tb36108.x
-
Kong YM, Okayasu I, Giraldo AA, Beisel KW, Sundick RS, Rose NR, et al. Tolerance to thyroglobulin by activating suppressor mechanisms. Ann N Y Acad Sci (1982) 392:191-209. doi:10.1111/j.1749-6632.1982.tb36108.x
-
(1982)
Ann N Y Acad Sci
, vol.392
, pp. 191-209
-
-
Kong, Y.M.1
Okayasu, I.2
Giraldo, A.A.3
Beisel, K.W.4
Sundick, R.S.5
Rose, N.R.6
-
22
-
-
0024502172
-
Resistance to experimental autoimmune thyroiditis: L3T4+ cells as mediators of both thyroglobulin-activated and TSH-induced suppression
-
doi:10.1016/0090-1229(89)90204-3
-
Kong YM, Giraldo AA, Waldmann H, Cobbold SP, Fuller BE. Resistance to experimental autoimmune thyroiditis: L3T4+ cells as mediators of both thyroglobulin-activated and TSH-induced suppression. Clin Immunol Immunopathol (1989) 51:38-54. doi:10.1016/0090-1229(89)90204-3
-
(1989)
Clin Immunol Immunopathol
, vol.51
, pp. 38-54
-
-
Kong, Y.M.1
Giraldo, A.A.2
Waldmann, H.3
Cobbold, S.P.4
Fuller, B.E.5
-
23
-
-
69649084091
-
Autoimmune thyroiditis as an indicator of autoimmune sequelae during cancer immunotherapy
-
doi:10.1016/j.autrev.2009.02.034
-
Kong YM, Jacob JB, Flynn JC, Elliott BE, Wei W-Z. Autoimmune thyroiditis as an indicator of autoimmune sequelae during cancer immunotherapy. Autoimmun Rev (2009) 9:28-33. doi:10.1016/j.autrev.2009.02.034
-
(2009)
Autoimmun Rev
, vol.9
, pp. 28-33
-
-
Kong, Y.M.1
Jacob, J.B.2
Flynn, J.C.3
Elliott, B.E.4
Wei, W.-Z.5
-
25
-
-
66949176637
-
Tumor regression following DNA vaccination and regulatory T cell depletion in neu transgenic mice leads to an increased risk for autoimmunity
-
doi:10.4049/jimmunol.0804074
-
Jacob JB, Kong YM, Nalbantoglu I, Snower DP, Wei W-Z. Tumor regression following DNA vaccination and regulatory T cell depletion in neu transgenic mice leads to an increased risk for autoimmunity. J Immunol (2009) 182:5873-81. doi:10.4049/jimmunol.0804074
-
(2009)
J Immunol
, vol.182
, pp. 5873-5881
-
-
Jacob, J.B.1
Kong, Y.M.2
Nalbantoglu, I.3
Snower, D.P.4
Wei, W.-Z.5
-
26
-
-
0029830079
-
HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) gene
-
doi:10.1084/jem.184.3.1167
-
Kong YM, Lomo LC, Motte RW, Giraldo AA, Baisch J, Strauss G, et al. HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) gene. J Exp Med (1996) 184:1167-72. doi:10.1084/jem.184.3.1167
-
(1996)
J Exp Med
, vol.184
, pp. 1167-1172
-
-
Kong, Y.M.1
Lomo, L.C.2
Motte, R.W.3
Giraldo, A.A.4
Baisch, J.5
Strauss, G.6
-
27
-
-
34547120471
-
Control of Her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells
-
doi:10.1158/0008-5472.CAN-06-4755
-
Jacob JB, Kong YM, Meroueh C, Snower DP, David CS, Ho Y-S, et al. Control of Her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells. Cancer Res (2007) 67:7020-7. doi:10.1158/0008-5472.CAN-06-4755
-
(2007)
Cancer Res
, vol.67
, pp. 7020-7027
-
-
Jacob, J.B.1
Kong, Y.M.2
Meroueh, C.3
Snower, D.P.4
David, C.S.5
Ho, Y.-S.6
-
28
-
-
0023269102
-
Resistance to experimental autoimmune thyroiditis induced by physiologic manipulation of thyroglobulin level
-
doi:10.1016/0090-1229(87)90115-2
-
Lewis M, Giraldo AA, Kong YM. Resistance to experimental autoimmune thyroiditis induced by physiologic manipulation of thyroglobulin level. Clin Immunol Immunopathol (1987) 45:92-104. doi:10.1016/0090-1229(87)90115-2
-
(1987)
Clin Immunol Immunopathol
, vol.45
, pp. 92-104
-
-
Lewis, M.1
Giraldo, A.A.2
Kong, Y.M.3
-
29
-
-
84890350664
-
Enhanced autoimmunity associated with induction of tumor immunity in thyroiditis-susceptible mice
-
doi:10.1089/thy.2013.0064
-
Kari S, Flynn JC, Zulfiqar M, Snower DP, Elliott BE, Kong YM. Enhanced autoimmunity associated with induction of tumor immunity in thyroiditis-susceptible mice. Thyroid (2013) 23:1590-9. doi:10.1089/thy.2013.0064
-
(2013)
Thyroid
, vol.23
, pp. 1590-1599
-
-
Kari, S.1
Flynn, J.C.2
Zulfiqar, M.3
Snower, D.P.4
Elliott, B.E.5
Kong, Y.M.6
-
30
-
-
50949125774
-
Pituitary autoimmunity: 30 years later
-
doi:10.1016/j.autrev.2008.04.016
-
Caturegli P, Lupi I, Landek-Salgado M, Kimura H, Rose NR. Pituitary autoimmunity: 30 years later. Autoimmun Rev (2008) 7:631-7. doi:10.1016/j.autrev.2008.04.016
-
(2008)
Autoimmun Rev
, vol.7
, pp. 631-637
-
-
Caturegli, P.1
Lupi, I.2
Landek-Salgado, M.3
Kimura, H.4
Rose, N.R.5
-
32
-
-
84896698630
-
Cutaneous melanoma
-
doi:10.1016/S0140-6736(13)60802-8
-
Eggermont AM, Spatz A, Robert C. Cutaneous melanoma. Lancet (2014) 383:816-27. doi:10.1016/S0140-6736(13)60802-8
-
(2014)
Lancet
, vol.383
, pp. 816-827
-
-
Eggermont, A.M.1
Spatz, A.2
Robert, C.3
-
33
-
-
84867402358
-
Growth hormone and proopiomelanocortin are targeted by autoantibodies in a patient with biopsy-proven IgG4-related hypophysitis
-
doi:10.1007/s11102-011-0338-8
-
Landek-Salgado MA, Leporati P, Lupi I, Geis A, Caturegli P. Growth hormone and proopiomelanocortin are targeted by autoantibodies in a patient with biopsy-proven IgG4-related hypophysitis. Pituitary (2012) 15:412-9. doi:10.1007/s11102-011-0338-8
-
(2012)
Pituitary
, vol.15
, pp. 412-419
-
-
Landek-Salgado, M.A.1
Leporati, P.2
Lupi, I.3
Geis, A.4
Caturegli, P.5
-
34
-
-
84863286066
-
Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays
-
doi:10.1530/EJE-11-1015
-
Smith CJ, Bensing S, Burns C, Robinson PJ, Kasperlik-Zaluska AA, Scott RJ, et al. Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays. Eur J Endocrinol (2012) 166:391-8. doi:10.1530/EJE-11-1015
-
(2012)
Eur J Endocrinol
, vol.166
, pp. 391-398
-
-
Smith, C.J.1
Bensing, S.2
Burns, C.3
Robinson, P.J.4
Kasperlik-Zaluska, A.A.5
Scott, R.J.6
-
35
-
-
84876215258
-
Pituitary autoimmunity in patients with diabetes mellitus and other endocrine disorders
-
doi:10.1007/BF03346747
-
Lupi I, Raffaelli V, Di Cianni G, Caturegli P, Manetti L, Ciccarone AM, et al. Pituitary autoimmunity in patients with diabetes mellitus and other endocrine disorders. J Endocrinol Invest (2013) 36:127-31. doi:10.1007/BF03346747
-
(2013)
J Endocrinol Invest
, vol.36
, pp. 127-131
-
-
Lupi, I.1
Raffaelli, V.2
Di Cianni, G.3
Caturegli, P.4
Manetti, L.5
Ciccarone, A.M.6
-
36
-
-
79959206459
-
CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans
-
doi:10.1158/1078-0432.CCR-11-0407
-
Huang RR, Jalil J, Economou JS, Chmielowski B, Koya RC, Mok S, et al. CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans. Clin Cancer Res (2011) 17:4101-9. doi:10.1158/1078-0432.CCR-11-0407
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4101-4109
-
-
Huang, R.R.1
Jalil, J.2
Economou, J.S.3
Chmielowski, B.4
Koya, R.C.5
Mok, S.6
-
37
-
-
84155163015
-
Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma
-
doi:10.1097/CJI.0b013e31823aa41c
-
Weber JS, Hamid O, Chasalow SD, Wu DY, Parker SM, Galbraith S, et al. Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma. J Immunother (2012) 35:89-97. doi:10.1097/CJI.0b013e31823aa41c
-
(2012)
J Immunother
, vol.35
, pp. 89-97
-
-
Weber, J.S.1
Hamid, O.2
Chasalow, S.D.3
Wu, D.Y.4
Parker, S.M.5
Galbraith, S.6
-
38
-
-
58149483422
-
4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
-
doi:10.1073/pnas.0810114105
-
4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit. Proc Natl Acad Sci U S A (2008) 105:20410-5. doi:10.1073/pnas.0810114105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20410-20415
-
-
Yuan, J.1
Gnjatic, S.2
Li, H.3
Powel, S.4
Gallardo, H.F.5
Ritter, E.6
-
41
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
doi:10.1056/NEJMoa1003466
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 363:711-23. doi:10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
42
-
-
77957273661
-
Control of Th2-mediated inflammation by regulatory T cells
-
doi:10.2353/ajpath.2010.090936
-
Venuprasad K, Kong YM, Farrar MA. Control of Th2-mediated inflammation by regulatory T cells. Am J Pathol (2010) 177:525-31. doi:10.2353/ajpath.2010.090936
-
(2010)
Am J Pathol
, vol.177
, pp. 525-531
-
-
Venuprasad, K.1
Kong, Y.M.2
Farrar, M.A.3
-
44
-
-
84886944764
-
Following up tumor-specific regulatory T cells in cancer patients
-
doi:10.4161/onci.25444
-
Zitvogel L, Tanchot C, Granier C, Tartour E. Following up tumor-specific regulatory T cells in cancer patients. Oncoimmunology (2013) 2:e25444. doi:10.4161/onci.25444
-
(2013)
Oncoimmunology
, vol.2
-
-
Zitvogel, L.1
Tanchot, C.2
Granier, C.3
Tartour, E.4
-
45
-
-
84864662070
-
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
-
doi:10.1038/nm.2883
-
Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med (2012) 18:1254-61. doi:10.1038/nm.2883
-
(2012)
Nat Med
, vol.18
, pp. 1254-1261
-
-
Walter, S.1
Weinschenk, T.2
Stenzl, A.3
Zdrojowy, R.4
Pluzanska, A.5
Szczylik, C.6
-
46
-
-
70449360735
-
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
-
doi:10.1172/JCI39608
-
Bonertz A, Weitz J, Pietsch DH, Rahbari NN, Schlude C, Ge Y, et al. Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. J Clin Invest (2009) 119:3311-21. doi:10.1172/JCI39608
-
(2009)
J Clin Invest
, vol.119
, pp. 3311-3321
-
-
Bonertz, A.1
Weitz, J.2
Pietsch, D.H.3
Rahbari, N.N.4
Schlude, C.5
Ge, Y.6
-
47
-
-
70350127838
-
4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts
-
doi:10.1158/0008-5472.CAN-09-2226
-
4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts. Cancer Res (2009) 69:8085-93. doi:10.1158/0008-5472.CAN-09-2226
-
(2009)
Cancer Res
, vol.69
, pp. 8085-8093
-
-
Jandus, C.1
Bioley, G.2
Dojcinovic, D.3
Derre, L.4
Baitsch, L.5
Wieckowski, S.6
-
48
-
-
84886943825
-
HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
-
doi:10.4161/onci.24962
-
Schmidt HH, Ge Y, Hartmann FJ, Conrad H, Klug F, Nittel S, et al. HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients. Oncoimmunology (2013) 2:e24962. doi:10.4161/onci.24962
-
(2013)
Oncoimmunology
, vol.2
-
-
Schmidt, H.H.1
Ge, Y.2
Hartmann, F.J.3
Conrad, H.4
Klug, F.5
Nittel, S.6
-
49
-
-
79956077563
-
T cell exhaustion
-
doi:10.1038/ni.2035
-
Wherry EJ. T cell exhaustion. Nat Immunol (2011) 12:492-9. doi:10.1038/ni.2035
-
(2011)
Nat Immunol
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
50
-
-
84879579673
-
4 and PD-1 blockade as cancer immunotherapy
-
doi:10.1189/jlb.1212621
-
4 and PD-1 blockade as cancer immunotherapy. J Leukoc Biol (2013) 94:25-39. doi:10.1189/jlb.1212621
-
(2013)
J Leukoc Biol
, vol.94
, pp. 25-39
-
-
Intlekofer, A.M.1
Thompson, C.B.2
-
51
-
-
84879599112
-
At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy
-
doi:10.1189/jlb.1212631
-
Callahan MK, Wolchok JD. At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy. J Leukoc Biol (2013) 94:41-53. doi:10.1189/jlb.1212631
-
(2013)
J Leukoc Biol
, vol.94
, pp. 41-53
-
-
Callahan, M.K.1
Wolchok, J.D.2
-
52
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
doi:10.1182/blood-2008-12-195792
-
Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, White DE, et al. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood (2009) 114:1537-44. doi:10.1182/blood-2008-12-195792
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
Johnson, L.A.2
Heemskerk, B.3
Wunderlich, J.R.4
Dudley, M.E.5
White, D.E.6
-
54
-
-
84891534246
-
Programmed death ligand-1 expression in non-small cell lung cancer
-
doi:10.1038/labinvest.2013.130
-
Velcheti V, Schalper KA, Carvajal DE, Anagnostou VK, Syrigos KN, Sznol M, et al. Programmed death ligand-1 expression in non-small cell lung cancer. Lab Invest (2014) 94:107-16. doi:10.1038/labinvest.2013.130
-
(2014)
Lab Invest
, vol.94
, pp. 107-116
-
-
Velcheti, V.1
Schalper, K.A.2
Carvajal, D.E.3
Anagnostou, V.K.4
Syrigos, K.N.5
Sznol, M.6
-
55
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
doi:10.1056/NEJMoa1200690
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med (2012) 366:2443-54. doi:10.1056/NEJMoa1200690
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
56
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
doi:10.1016/S1074-7613(00)80089-8
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity (1999) 11:141-51. doi:10.1016/S1074-7613(00)80089-8
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
57
-
-
10744220884
-
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice
-
doi:10.1038/nm955
-
Okazaki T, Tanaka Y, Nishio R, Mitsuiye T, Mizoguchi A, Wang J, et al. Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. Nat Med (2003) 9:1477-83. doi:10.1038/nm955
-
(2003)
Nat Med
, vol.9
, pp. 1477-1483
-
-
Okazaki, T.1
Tanaka, Y.2
Nishio, R.3
Mitsuiye, T.4
Mizoguchi, A.5
Wang, J.6
-
58
-
-
85047655952
-
PD-1 inhibitor becomes "breakthrough therapy"
-
doi:10.1158/2159-8290.CD-NB2013-074
-
PD-1 inhibitor becomes "breakthrough therapy". Cancer Discov (2013) 3:OF14. doi:10.1158/2159-8290.CD-NB2013-074
-
(2013)
Cancer Discov
, vol.3
-
-
-
59
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
doi:10.1056/NEJMoa1305133
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med (2013) 369:134-44. doi:10.1056/NEJMoa1305133
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
60
-
-
84892365940
-
Checkpoint blocking antibodies in cancer immunotherapy
-
doi:10.1016/j.febslet.2013.10.015
-
Kyi C, Postow MA. Checkpoint blocking antibodies in cancer immunotherapy. FEBS Lett (2014) 588:368-76. doi:10.1016/j.febslet.2013.10.015
-
(2014)
FEBS Lett
, vol.588
, pp. 368-376
-
-
Kyi, C.1
Postow, M.A.2
-
61
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
doi:10.1200/JCO.2013.53.0105
-
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol (2014) 32:1020-30. doi:10.1200/JCO.2013.53.0105
-
(2014)
J Clin Oncol
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
62
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
doi:10.1056/NEJMoa1200694
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med (2012) 366:2455-65. doi:10.1056/NEJMoa1200694
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
-
63
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
doi:10.1038/85330
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol (2001) 2:261-8. doi:10.1038/85330
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
-
64
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
doi:10.1084/jem.193.7.839
-
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med (2001) 193:839-46. doi:10.1084/jem.193.7.839
-
(2001)
J Exp Med
, vol.193
, pp. 839-846
-
-
Tseng, S.Y.1
Otsuji, M.2
Gorski, K.3
Huang, X.4
Slansky, J.E.5
Pai, S.I.6
-
65
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
doi:10.1038/ni.1790
-
Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol (2009) 10:1185-92. doi:10.1038/ni.1790
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
-
67
-
-
84879104519
-
4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
-
doi:10.1158/0008-5472.CAN-12-4100
-
4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. Cancer Res (2013) 73:3591-603. doi:10.1158/0008-5472.CAN-12-4100
-
(2013)
Cancer Res
, vol.73
, pp. 3591-3603
-
-
Duraiswamy, J.1
Kaluza, K.M.2
Freeman, G.J.3
Coukos, G.4
-
70
-
-
0034679567
-
+ regulatory cells that control intestinal inflammation
-
doi:10.1084/jem.192.2.295
-
+ regulatory cells that control intestinal inflammation. J Exp Med (2000) 192:295-302. doi:10.1084/jem.192.2.295
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmström, V.2
Powrie, F.3
-
71
-
-
0034194329
-
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using C.T.L.A-4 blockade
-
Hurwitz AA, Foster BA, Kwon ED, Truong T, Choi EM, Greenberg NM, et al. Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade. Cancer Res (2000) 60:2444-8.
-
(2000)
Cancer Res
, vol.60
, pp. 2444-2448
-
-
Hurwitz, A.A.1
Foster, B.A.2
Kwon, E.D.3
Truong, T.4
Choi, E.M.5
Greenberg, N.M.6
-
72
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
doi:10.1084/jem.20022125
-
Ansari MJI, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med (2003) 198:63-9. doi:10.1084/jem.20022125
-
(2003)
J Exp Med
, vol.198
, pp. 63-69
-
-
Ansari, M.J.I.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
-
73
-
-
23444449846
-
Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation
-
doi:10.1096/fj.04-3228fje
-
Kwidzinski E, Bunse J, Aktas O, Richter D, Mutlu L, Zipp F, et al. Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation. FASEB J (2005) 19:1347-9. doi:10.1096/fj.04-3228fje
-
(2005)
FASEB J
, vol.19
, pp. 1347-1349
-
-
Kwidzinski, E.1
Bunse, J.2
Aktas, O.3
Richter, D.4
Mutlu, L.5
Zipp, F.6
-
75
-
-
0242580070
-
+ regulatory T cells cure murine colitis: the role of IL-10, TGF-β, and CTLA4
-
doi:10.4049/jimmunol.171.10.5012
-
+ regulatory T cells cure murine colitis: the role of IL-10, TGF-β, and CTLA4. J Immunol (2003) 171:5012-7. doi:10.4049/jimmunol.171.10.5012
-
(2003)
J Immunol
, vol.171
, pp. 5012-5017
-
-
Liu, H.1
Hu, B.2
Xu, D.3
Liew, F.Y.4
-
76
-
-
0034657891
-
4 in patients with autoimmune thyroid disease
-
doi:10.4049/jimmunol.164.10.5015
-
4 in patients with autoimmune thyroid disease. J Immunol (2000) 164:5015-8. doi:10.4049/jimmunol.164.10.5015
-
(2000)
J Immunol
, vol.164
, pp. 5015-5018
-
-
Oaks, M.K.1
Hallett, K.M.2
-
78
-
-
0031047696
-
4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis
-
4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. J Neuroimmunol (1997) 73:57-62.
-
(1997)
J Neuroimmunol
, vol.73
, pp. 57-62
-
-
Hurwitz, A.A.1
Sullivan, T.J.2
Krummel, M.F.3
Sobel, R.A.4
Allison, J.P.5
-
79
-
-
49249089425
-
4 and PD-1 pathways
-
doi:10.1111/j.1600-065X.2008.00662.x
-
4 and PD-1 pathways. Immunol Rev (2008) 224:166-82. doi:10.1111/j.1600-065X.2008.00662.x
-
(2008)
Immunol Rev
, vol.224
, pp. 166-182
-
-
Fife, B.T.1
Bluestone, J.A.2
-
80
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
doi:10.1056/NEJMoa1302369
-
Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med (2013) 369:122-33. doi:10.1056/NEJMoa1302369
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
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