-
1
-
-
77949262985
-
Tumor necrosis factor blockade and the risk of viral infection
-
Kim SY, Solomon DH. Tumor necrosis factor blockade and the risk of viral infection. Nat Rev Rheumatol. 2010;6(3): 165-174.
-
(2010)
Nat Rev Rheumatol
, vol.6
, Issue.3
, pp. 165-174
-
-
Kim, S.Y.1
Solomon, D.H.2
-
2
-
-
84889673425
-
Infectious and malignant complications of TNF inhibitor therapy in IBD
-
Targownik LE, Bernstein CN. Infectious and malignant complications of TNF inhibitor therapy in IBD. Am J Gastroenterol. 2013;108(12): 1835-1842.
-
(2013)
Am J Gastroenterol
, vol.108
, Issue.12
, pp. 1835-1842
-
-
Targownik, L.E.1
Bernstein, C.N.2
-
3
-
-
77950355043
-
Unraveling the genetics of autoimmunity
-
Zenewicz LA, Abraham C, Flavell RA, Cho JH. Unraveling the genetics of autoimmunity. Cell. 2010;140(6): 791-797.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 791-797
-
-
Zenewicz, L.A.1
Abraham, C.2
Flavell, R.A.3
Cho, J.H.4
-
5
-
-
84862682781
-
The immunogenetic architecture of autoimmune disease
-
Goris A, Liston A. The immunogenetic architecture of autoimmune disease. Cold Spring Harb Perspect Biol. 2012;4(3): A007260.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
, Issue.3
, pp. a007260
-
-
Goris, A.1
Liston, A.2
-
6
-
-
0025780344
-
T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects
-
Liblau R, et al. T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects. Eur J Immunol. 1991;21(6): 1391-1395.
-
(1991)
Eur J Immunol
, vol.21
, Issue.6
, pp. 1391-1395
-
-
Liblau, R.1
-
7
-
-
0025370870
-
T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
-
Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature. 1990;346(6280): 183-187.
-
(1990)
Nature
, vol.346
, Issue.6280
, pp. 183-187
-
-
Ota, K.1
Matsui, M.2
Milford, E.L.3
Mackin, G.A.4
Weiner, H.L.5
Hafler, D.A.6
-
8
-
-
77958584113
-
Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling
-
Ghoreschi K, et al. Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling. Nature. 2010;467(7318): 967-971.
-
(2010)
Nature
, vol.467
, Issue.7318
, pp. 967-971
-
-
Ghoreschi, K.1
-
9
-
-
84859543711
-
Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies
-
Vandenbroeck K. Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies. J Interferon Cytokine Res. 2012;32(4): 139-151.
-
(2012)
J Interferon Cytokine Res
, vol.32
, Issue.4
, pp. 139-151
-
-
Vandenbroeck, K.1
-
10
-
-
73849124607
-
Ustekinumab: Lessons learned from targeting interleukin-12/23p40 in immune-mediated diseases
-
Elliott M, et al. Ustekinumab: Lessons learned from targeting interleukin-12/23p40 in immune-mediated diseases. Ann N Y Acad Sci. 2009;1182: 97-110.
-
(2009)
Ann N Y Acad Sci
, vol.1182
, pp. 97-110
-
-
Elliott, M.1
-
11
-
-
84859017988
-
Brodalumab, an anti-interleukin- 17-receptor antibody for psoriasis
-
Papp KA, et al. Brodalumab, an anti-interleukin- 17-receptor antibody for psoriasis. N Engl J Med. 2012;366(13): 1181-1189.
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1181-1189
-
-
Papp, K.A.1
-
12
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett CL, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet. 2001; 27(1): 20-21.
-
(2001)
Nat Genet
, vol.27
, Issue.1
, pp. 20-21
-
-
Bennett, C.L.1
-
13
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zincfinger domains
-
Finnish-German APECED Consortium. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zincfinger domains. Nat Genet. 1997;17(4): 399-403.
-
(1997)
Nat Genet
, vol.17
, Issue.4
, pp. 399-403
-
-
-
14
-
-
0029025441
-
Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
-
Fisher GH, et al. Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell. 1995;81(6): 935-946.
-
(1995)
Cell
, vol.81
, Issue.6
, pp. 935-946
-
-
Fisher, G.H.1
-
15
-
-
82255191977
-
TLR-dependent T cell activation in autoimmunity
-
Mills KH. TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol. 2011;11(12): 807-822.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 807-822
-
-
Mills, K.H.1
-
16
-
-
84891818955
-
Complexities in the relationship between infection and autoimmunity
-
Root-Bernstein R, Fairweather D. Complexities in the relationship between infection and autoimmunity. Curr Allergy Asthma Rep. 2014;14(1): 407.
-
(2014)
Curr Allergy Asthma Rep
, vol.14
, Issue.1
, pp. 407
-
-
Root-Bernstein, R.1
Fairweather, D.2
-
17
-
-
36549034729
-
Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain
-
Serafini B, et al. Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain. J Exp Med. 2007;204(12): 2899-2912.
-
(2007)
J Exp Med
, vol.204
, Issue.12
, pp. 2899-2912
-
-
Serafini, B.1
-
18
-
-
84899705732
-
Periodontitis and porphyromonas gingivalis in patients with rheumatoid arthritis
-
Mikuls TR, et al. Periodontitis and porphyromonas gingivalis in patients with rheumatoid arthritis. Arthritis Rheumatol. 2014;66(5): 1090-1100.
-
(2014)
Arthritis Rheumatol
, vol.66
, Issue.5
, pp. 1090-1100
-
-
Mikuls, T.R.1
-
19
-
-
77958119730
-
Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
-
Ochoa-Repáraz J, et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J Immunol. 2010;185(7): 4101-4108.
-
(2010)
J Immunol
, vol.185
, Issue.7
, pp. 4101-4108
-
-
Ochoa-Repáraz, J.1
-
20
-
-
84897138296
-
Role of the microbiota in immunity and inflammation
-
Belkaid Y, Hand TW. Role of the microbiota in immunity and inflammation. Cell. 2014;157(1): 121-141.
-
(2014)
Cell
, vol.157
, Issue.1
, pp. 121-141
-
-
Belkaid, Y.1
Hand, T.W.2
-
21
-
-
80054927213
-
Microbiota and autoimmune disease: The hosted self
-
Mathis D, Benoist C. Microbiota and autoimmune disease: The hosted self. Cell Host Microbe. 2011;10(4): 297-301.
-
(2011)
Cell Host Microbe
, vol.10
, Issue.4
, pp. 297-301
-
-
Mathis, D.1
Benoist, C.2
-
22
-
-
84891776162
-
Photosensitivity, apoptosis, and cytokines in the pathogenesis of lupus erythematosus: A critical review
-
Kuhn A, Wenzel J, Weyd H. Photosensitivity, apoptosis, and cytokines in the pathogenesis of lupus erythematosus: A critical review. Clin Rev Allergy Immunol. 2014;47(2): 148-162.
-
(2014)
Clin Rev Allergy Immunol
, vol.47
, Issue.2
, pp. 148-162
-
-
Kuhn, A.1
Wenzel, J.2
Weyd, H.3
-
23
-
-
0034614886
-
The induction of tolerance by dendritic cells that have captured apoptotic cells
-
Steinman RM, Turley S, Mellman I, Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J Exp Med. 2000;191(3): 411-416.
-
(2000)
J Exp Med
, vol.191
, Issue.3
, pp. 411-416
-
-
Steinman, R.M.1
Turley, S.2
Mellman, I.3
Inaba, K.4
-
24
-
-
15444365480
-
Defective B cell tolerance checkpoints in systemic lupus erythematosus
-
Yurasov S, et al. Defective B cell tolerance checkpoints in systemic lupus erythematosus. J Exp Med. 2005;201(5): 703-711.
-
(2005)
J Exp Med
, vol.201
, Issue.5
, pp. 703-711
-
-
Yurasov, S.1
-
25
-
-
56649095905
-
T regulatory cells in autoimmune diabetes: Past challenges, future prospects
-
Bluestone JA, Tang Q, Sedwick CE. T regulatory cells in autoimmune diabetes: Past challenges, future prospects. J Clin Immunol. 2008;28(6): 677-684.
-
(2008)
J Clin Immunol
, vol.28
, Issue.6
, pp. 677-684
-
-
Bluestone, J.A.1
Tang, Q.2
Sedwick, C.E.3
-
26
-
-
84866740799
-
Unconventional recognition of peptides by T cells and the implications for autoimmunity
-
Mohan JF, Unanue ER. Unconventional recognition of peptides by T cells and the implications for autoimmunity. Nat Rev Immunol. 2012;12(10): 721-728.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.10
, pp. 721-728
-
-
Mohan, J.F.1
Unanue, E.R.2
-
27
-
-
84855476371
-
Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion
-
Mohan JF, Petzold SJ, Unanue ER. Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion. J Exp Med. 2011;208(12): 2375-2383.
-
(2011)
J Exp Med
, vol.208
, Issue.12
, pp. 2375-2383
-
-
Mohan, J.F.1
Petzold, S.J.2
Unanue, E.R.3
-
28
-
-
77949872804
-
Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes
-
Mohan JF, Levisetti MG, Calderon B, Herzog JW, Petzold SJ, Unanue ER. Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes. Nat Immunol. 2010;11(4): 350-354.
-
(2010)
Nat Immunol
, vol.11
, Issue.4
, pp. 350-354
-
-
Mohan, J.F.1
Levisetti, M.G.2
Calderon, B.3
Herzog, J.W.4
Petzold, S.J.5
Unanue, E.R.6
-
29
-
-
80052184362
-
Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity
-
Kawasaki T, Kawai T, Akira S. Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity. Immunol Rev. 2011;243(1): 61-73.
-
(2011)
Immunol Rev
, vol.243
, Issue.1
, pp. 61-73
-
-
Kawasaki, T.1
Kawai, T.2
Akira, S.3
-
30
-
-
39549107115
-
Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
-
Turer EE, et al. Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20. J Exp Med. 2008;205(2): 451-464.
-
(2008)
J Exp Med
, vol.205
, Issue.2
, pp. 451-464
-
-
Turer, E.E.1
-
31
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science. 2006;312(5780): 1669-1672.
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
32
-
-
1542313881
-
Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-A
-
Boyman O, Hefti HP, Conrad C, Nickoloff BJ, Suter M, Nestle FO. Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-A. J Exp Med. 2004;199(5): 731-736.
-
(2004)
J Exp Med
, vol.199
, Issue.5
, pp. 731-736
-
-
Boyman, O.1
Hefti, H.P.2
Conrad, C.3
Nickoloff, B.J.4
Suter, M.5
Nestle, F.O.6
-
33
-
-
33748447541
-
Type I interferon in systemic lupus erythematosus and other autoimmune diseases
-
Banchereau J, Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity. 2006;25(3): 383-392.
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 383-392
-
-
Banchereau, J.1
Pascual, V.2
-
34
-
-
84892707974
-
Treatment of psoriasis and psoriatic arthritis
-
Papoutsaki M, Costanzo A. Treatment of psoriasis and psoriatic arthritis. BioDrugs. 2013;27(suppl 1): 3-12.
-
(2013)
BioDrugs
, vol.27
, pp. 3-12
-
-
Papoutsaki, M.1
Costanzo, A.2
-
35
-
-
70349967965
-
Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis
-
Taylor PC, Feldmann M. Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol. 2009;5(10): 578-582.
-
(2009)
Nat Rev Rheumatol
, vol.5
, Issue.10
, pp. 578-582
-
-
Taylor, P.C.1
Feldmann, M.2
-
37
-
-
84887992906
-
Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: A randomised, double-blind, placebo-controlled trial
-
Baeten D, et al. Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: A randomised, double-blind, placebo-controlled trial. Lancet. 2013;382(9906): 1705-1713.
-
(2013)
Lancet
, vol.382
, Issue.9906
, pp. 1705-1713
-
-
Baeten, D.1
-
38
-
-
84876292569
-
Effect of IL-17A blockade with secukinumab in autoimmune diseases
-
Patel DD, Lee DM, Kolbinger F, Antoni C. Effect of IL-17A blockade with secukinumab in autoimmune diseases. Ann Rheum Dis. 2013;72(suppl 2): Ii116-ii123.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. ii116-ii123
-
-
Patel, D.D.1
Lee, D.M.2
Kolbinger, F.3
Antoni, C.4
-
39
-
-
78649526238
-
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases
-
Buckner JH. Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases. Nat Rev Immunol. 2010;10(12): 849-859.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.12
, pp. 849-859
-
-
Buckner, J.H.1
-
40
-
-
29144516273
-
Global natural regulatory T cell depletion in active systemic lupus erythematosus
-
Miyara M, et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol. 2005;175(12): 8392-8400.
-
(2005)
J Immunol
, vol.175
, Issue.12
, pp. 8392-8400
-
-
Miyara, M.1
-
41
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja A, et al. Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest. 2002;109(1): 131-140.
-
(2002)
J Clin Invest
, vol.109
, Issue.1
, pp. 131-140
-
-
Kukreja, A.1
-
42
-
-
80051801522
-
Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin
-
Bovenschen HJ, van de Kerkhof PC, van Erp PE, Woestenenk R, Joosten I, Koenen HJ. Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. J Invest Dermatol. 2011;131(9): 1853-1860.
-
(2011)
J Invest Dermatol
, vol.131
, Issue.9
, pp. 1853-1860
-
-
Bovenschen, H.J.1
Van De Kerkhof, P.C.2
Van Erp, P.E.3
Woestenenk, R.4
Joosten, I.5
Koenen, H.J.6
-
43
-
-
84896786878
-
Memory regulatory T cells reside in human skin
-
Sanchez Rodriguez R, et al. Memory regulatory T cells reside in human skin. J Clin Invest. 2014;124(3): 1027-1036.
-
(2014)
J Clin Invest
, vol.124
, Issue.3
, pp. 1027-1036
-
-
Sanchez Rodriguez, R.1
-
44
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
Tang Q, et al. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity. 2008;28(5): 687-697.
-
(2008)
Immunity
, vol.28
, Issue.5
, pp. 687-697
-
-
Tang, Q.1
-
45
-
-
1042269477
-
IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells
-
Zhang X. IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells. Int Immunol. 2004;16(2): 249-256.
-
(2004)
Int Immunol
, vol.16
, Issue.2
, pp. 249-256
-
-
Zhang, X.1
-
46
-
-
84355162741
-
Response to self antigen imprints regulatory memory in tissues
-
Rosenblum MD, Gratz IK, Paw JS, Lee K, Marshak- Rothstein A, Abbas AK. Response to self antigen imprints regulatory memory in tissues. Nature. 2011;480(7378): 538-542.
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 538-542
-
-
Rosenblum, M.D.1
Gratz, I.K.2
Paw, J.S.3
Lee, K.4
Marshak-Rothstein, A.5
Abbas, A.K.6
-
47
-
-
82555196118
-
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
-
Saadoun D, et al. Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis. N Engl J Med. 2011;365(22): 2067-2077.
-
(2011)
N Engl J Med
, vol.365
, Issue.22
, pp. 2067-2077
-
-
Saadoun, D.1
-
48
-
-
84904130542
-
Effects of low-dose recombinant interleukin 2 to promote T-regulatory cells in alopecia areata
-
Castela E, et al. Effects of low-dose recombinant interleukin 2 to promote T-regulatory cells in alopecia areata. JAMA Dermatol. 2014;150(7): 748-751.
-
(2014)
JAMA Dermatol
, vol.150
, Issue.7
, pp. 748-751
-
-
Castela, E.1
-
49
-
-
82555168440
-
Interleukin-2 and regulatory T cells in graft-versus-host disease
-
Koreth J, et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med. 2011;365(22): 2055-2066.
-
(2011)
N Engl J Med
, vol.365
, Issue.22
, pp. 2055-2066
-
-
Koreth, J.1
-
50
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
Di Ianni M, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood. 2011;117(14): 3921-3928.
-
(2011)
Blood
, vol.117
, Issue.14
, pp. 3921-3928
-
-
Di Ianni, M.1
-
51
-
-
84892502529
-
CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
-
Smigiel KS, et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med. 2014;211(1): 121-136.
-
(2014)
J Exp Med
, vol.211
, Issue.1
, pp. 121-136
-
-
Smigiel, K.S.1
-
52
-
-
84897932501
-
Regulatory T-cell homeostasis: Steady-state maintenance and modulation during inflammation
-
Smigiel KS, Srivastava S, Stolley JM, Campbell DJ. Regulatory T-cell homeostasis: Steady-state maintenance and modulation during inflammation. Immunol Rev. 2014;259(1): 40-59.
-
(2014)
Immunol Rev
, vol.259
, Issue.1
, pp. 40-59
-
-
Smigiel, K.S.1
Srivastava, S.2
Stolley, J.M.3
Campbell, D.J.4
-
53
-
-
27944455288
-
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen
-
Knoechel B, Lohr J, Kahn E, Bluestone JA, Abbas AK. Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med. 2005;202(10): 1375-1386.
-
(2005)
J Exp Med
, vol.202
, Issue.10
, pp. 1375-1386
-
-
Knoechel, B.1
Lohr, J.2
Kahn, E.3
Bluestone, J.A.4
Abbas, A.K.5
-
54
-
-
84907909000
-
Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
-
Kuehn HS, et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science. 2014;345(6204): 1623-1627.
-
(2014)
Science
, vol.345
, Issue.6204
, pp. 1623-1627
-
-
Kuehn, H.S.1
-
55
-
-
84938070889
-
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
-
Schubert D, et al. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. Nat Med. 2014;20(12): 1410-1416.
-
(2014)
Nat Med
, vol.20
, Issue.12
, pp. 1410-1416
-
-
Schubert, D.1
-
56
-
-
71149119191
-
Fc receptor biology and systemic lupus erythematosus
-
Jovanovic V, Dai X, Lim YT, Kemeny DM, MacAry PA. Fc? receptor biology and systemic lupus erythematosus. Int J Rheum Dis. 2009;12(4): 293-298.
-
(2009)
Int J Rheum Dis
, vol.12
, Issue.4
, pp. 293-298
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Jovanovic, V.1
Dai, X.2
Lim, Y.T.3
Kemeny, D.M.4
MacAry, P.A.5
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