CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion

Immunity

Volumn 43, Issue 5, 2015, Pages 896-908

  Legoux, Francois P ^a,f   Lim, Jong Baeck ^a,g   Cauley, Andrew W ^a   Dikiy, Stanislav ^b   Ertelt, James ^c,h   Mariani, Thomas J ^d   Sparwasser, Tim ^e   Way, Sing Sing ^c,h   Moon, James J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Division of Infectious Diseases and Perinatal Institute   (United States)

^d UNIVERSITY OF ROCHESTER   (United States)

^e INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^f PSL RESEARCH UNIVERSITY   (France)

^g Yonsei University College of Medicine   (South Korea)

^h CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; INTERLEUKIN 17; MESSENGER RNA; T LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR FOXP3; AUTOANTIGEN; CANCER VACCINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IN VIVO STUDY; INTESTINAL TISSUE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY T LYMPHOCYTE; STEADY STATE; T LYMPHOCYTE SUBPOPULATION; TISSUE SPECIFICITY; ANIMAL; C57BL MOUSE; IMMUNOLOGY;

ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; CANCER VACCINES; CD4-POSITIVE T-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; MICE; MICE, INBRED C57BL; T-LYMPHOCYTES, REGULATORY;

EID: 84947441287     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.10.011     Document Type: Article

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