메뉴 건너뛰기




Volumn 397, Issue , 2016, Pages 215-227

Inflammasomes in pneumococcal infection: Innate immune sensing and bacterial evasion strategies

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR 2; PATTERN RECOGNITION RECEPTOR; PROTEIN AIM2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84982706279     PISSN: 0070217X     EISSN: 21969965     Source Type: Book Series    
DOI: 10.1007/978-3-319-41171-2_11     Document Type: Chapter
Times cited : (29)

References (70)
  • 1
    • 0037222927 scopus 로고    scopus 로고
    • Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae
    • Abeyta M, Hardy GG, Yother J (2003) Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae. Infect Immun 71(1):218–225
    • (2003) Infect Immun , vol.71 , Issue.1 , pp. 218-225
    • Abeyta, M.1    Hardy, G.G.2    Yother, J.3
  • 6
    • 80052352663 scopus 로고    scopus 로고
    • Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. Pneumoniae colonization in mice
    • Davis KM, Nakamura S, Weiser JN (2011) Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. J Clin Investig 121(9):3666–3676. doi:10.1172/JCI57761
    • (2011) J Clin Investig , vol.121 , Issue.9 , pp. 3666-3676
    • Davis, K.M.1    Nakamura, S.2    Weiser, J.N.3
  • 8
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth SC, Colegio OR, O’Connor W, Sutterwala FS, Flavell RA (2008) Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453 (7198):1122–1126. doi:10.1038/nature06939
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O’Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 10
    • 84900401399 scopus 로고    scopus 로고
    • Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection
    • Fang R, Hara H, Sakai S, Hernandez-Cuellar E, Mitsuyama M, Kawamura I, Tsuchiya K (2014) Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection. Infect Immun 82(6):2310–2317. doi:10.1128/IAI.01572-14
    • (2014) Infect Immun , vol.82 , Issue.6 , pp. 2310-2317
    • Fang, R.1    Hara, H.2    Sakai, S.3    Hernandez-Cuellar, E.4    Mitsuyama, M.5    Kawamura, I.6    Tsuchiya, K.7
  • 12
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES (2009) AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458(7237):509–513. doi:10.1038/nature07710
    • (2009) Nature , vol.458 , Issue.7237 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 16
    • 84905659601 scopus 로고    scopus 로고
    • The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent
    • Harvey RM, Hughes CE, Paton AW, Trappetti C, Tweten RK, Paton JC (2014) The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. PLoS ONE 9(8):e103625. doi:10.1371/journal.pone.0103625
    • (2014) Plos ONE , vol.9 , Issue.8
    • Harvey, R.M.1    Hughes, C.E.2    Paton, A.W.3    Trappetti, C.4    Tweten, R.K.5    Paton, J.C.6
  • 18
    • 84879747324 scopus 로고    scopus 로고
    • The pneumococcus: Epidemiology, microbiology, and pathogenesis
    • Henriques-Normark B, Tuomanen EI (2013) The pneumococcus: epidemiology, microbiology, and pathogenesis. Cold Spring Harb Perspect Med 3(7). doi:10.1101/cshperspect.a010215
    • (2013) Cold Spring Harb Perspect Med , vol.3 , Issue.7
    • Henriques-Normark, B.1    Tuomanen, E.I.2
  • 19
    • 40549088892 scopus 로고    scopus 로고
    • Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis
    • Hirst RA, Gosai B, Rutman A, Guerin CJ, Nicotera P, Andrew PW, O’Callaghan C (2008) Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis. J Infect Dis 197(5):744–751. doi:10.1086/527322
    • (2008) J Infect Dis , vol.197 , Issue.5 , pp. 744-751
    • Hirst, R.A.1    Gosai, B.2    Rutman, A.3    Guerin, C.J.4    Nicotera, P.5    Rew, P.W.6    O’Callaghan, C.7
  • 20
    • 81455154929 scopus 로고    scopus 로고
    • The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
    • Hoegen T, Tremel N, Klein M, Angele B, Wagner H, Kirschning C, Pfister HW, Fontana A, Hammerschmidt S, Koedel U (2011) The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J Immunol 187(10):5440–5451. doi:10.4049/jimmunol.1100790
    • (2011) J Immunol , vol.187 , Issue.10 , pp. 5440-5451
    • Hoegen, T.1    Tremel, N.2    Klein, M.3    Angele, B.4    Wagner, H.5    Kirschning, C.6    Pfister, H.W.7    Fontana, A.8    Hammerschmidt, S.9    Koedel, U.10
  • 21
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9(8):847–856. doi:10.1038/ni.1631
    • (2008) Nat Immunol , vol.9 , Issue.8 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6    Fitzgerald, K.A.7    Latz, E.8
  • 23
    • 76749095490 scopus 로고    scopus 로고
    • The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms
    • Hyams C, Camberlein E, Cohen JM, Bax K, Brown JS (2010) The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms. Infect Immun 78(2):704–715. doi:10.1128/IAI.00881-09
    • (2010) Infect Immun , vol.78 , Issue.2 , pp. 704-715
    • Hyams, C.1    Camberlein, E.2    Cohen, J.M.3    Bax, K.4    Brown, J.S.5
  • 25
    • 0036263426 scopus 로고    scopus 로고
    • Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type
    • Kadioglu A, Taylor S, Iannelli F, Pozzi G, Mitchell TJ, Andrew PW (2002) Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type. Infect Immun 70(6):2886–2890
    • (2002) Infect Immun , vol.70 , Issue.6 , pp. 2886-2890
    • Kadioglu, A.1    Taylor, S.2    Iannelli, F.3    Pozzi, G.4    Mitchell, T.J.5    Rew, P.W.6
  • 26
    • 40949162838 scopus 로고    scopus 로고
    • The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease
    • Kadioglu A, Weiser JN, Paton JC, Andrew PW (2008) The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol 6(4):288–301. doi:10.1038/nrmicro1871
    • (2008) Nat Rev Microbiol , vol.6 , Issue.4 , pp. 288-301
    • Kadioglu, A.1    Weiser, J.N.2    Paton, J.C.3    Rew, P.W.4
  • 29
    • 84922553500 scopus 로고    scopus 로고
    • Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux
    • Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E (2015) Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. J Immunol 194(4):1763–1775. doi:10.4049/jimmunol.1401624
    • (2015) J Immunol , vol.194 , Issue.4 , pp. 1763-1775
    • Karmakar, M.1    Katsnelson, M.2    Malak, H.A.3    Greene, N.G.4    Howell, S.J.5    Hise, A.G.6    Camilli, A.7    Kadioglu, A.8    Dubyak, G.R.9    Pearlman, E.10
  • 30
    • 30744464885 scopus 로고    scopus 로고
    • Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin
    • Kirkham LA, Jefferies JM, Kerr AR, Jing Y, Clarke SC, Smith A, Mitchell TJ (2006) Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin. J Clin Microbiol 44(1):151–159. doi:10.1128/JCM.44.1.151-159.2006
    • (2006) J Clin Microbiol , vol.44 , Issue.1 , pp. 151-159
    • Kirkham, L.A.1    Jefferies, J.M.2    Kerr, A.R.3    Jing, Y.4    Clarke, S.C.5    Smith, A.6    Mitchell, T.J.7
  • 31
    • 1342324587 scopus 로고    scopus 로고
    • Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
    • Knapp S, Wieland CW, van‘t Veer C, Takeuchi O, Akira S, Florquin S, van der Poll T (2004) Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J Immunol 172 5:3132–3138
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 3132-3138
    • Knapp, S.1    Wieland, C.W.2    Van‘t Veer, C.3    Takeuchi, O.4    Akira, S.5    Florquin, S.6    van der Poll, T.7
  • 32
    • 0036193998 scopus 로고    scopus 로고
    • Role of Caspase-1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice
    • Koedel U, Winkler F, Angele B, Fontana A, Flavell RA, Pfister HW (2002) Role of Caspase-1 in experimental pneumococcal meningitis: evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice. Ann Neurol 51(3):319–329
    • (2002) Ann Neurol , vol.51 , Issue.3 , pp. 319-329
    • Koedel, U.1    Winkler, F.2    Angele, B.3    Fontana, A.4    Flavell, R.A.5    Pfister, H.W.6
  • 33
    • 84856020851 scopus 로고    scopus 로고
    • Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs
    • Koppe U, Hogner K, Doehn JM, Muller HC, Witzenrath M, Gutbier B, Bauer S, Pribyl T, Hammerschmidt S, Lohmeyer J, Suttorp N, Herold S, Opitz B (2012a) Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J Immunol 188(2):811–817. doi:10.4049/jimmunol.1004143
    • (2012) J Immunol , vol.188 , Issue.2 , pp. 811-817
    • Koppe, U.1    Hogner, K.2    Doehn, J.M.3    Muller, H.C.4    Witzenrath, M.5    Gutbier, B.6    Bauer, S.7    Pribyl, T.8    Hammerschmidt, S.9    Lohmeyer, J.10    Suttorp, N.11    Herold, S.12    Opitz, B.13
  • 34
    • 84858297649 scopus 로고    scopus 로고
    • Recognition of Streptococcus pneumoniae by the innate immune system
    • Koppe U, Suttorp N, Opitz B (2012b) Recognition of Streptococcus pneumoniae by the innate immune system. Cell Microbiol 14(4):460–466. doi:10.1111/j.1462-5822.2011.01746.x
    • (2012) Cell Microbiol , vol.14 , Issue.4 , pp. 460-466
    • Koppe, U.1    Suttorp, N.2    Opitz, B.3
  • 35
    • 84895073832 scopus 로고    scopus 로고
    • Immunosenescence and pneumococcal disease: An imbalance in host-pathogen interactions
    • Krone CL, van de Groep K, Trzcinski K, Sanders EA, Bogaert D (2014) Immunosenescence and pneumococcal disease: an imbalance in host-pathogen interactions. Lancet Respir Med 2 (2):141–153. doi:10.1016/S2213-2600(13)70165-6
    • (2014) Lancet Respir Med , vol.2 , Issue.2 , pp. 141-153
    • Krone, C.L.1    Van De Groep, K.2    Trzcinski, K.3    Sanders, E.A.4    Bogaert, D.5
  • 38
    • 77955438285 scopus 로고    scopus 로고
    • Invasive serotype 1 Streptococcus pneumoniae outbreaks in the South Pacific from 2000 to 2007
    • Le Hello S, Watson M, Levy M, Marcon S, Brown M, Yvon JF, Missotte I, Garin B (2010) Invasive serotype 1 Streptococcus pneumoniae outbreaks in the South Pacific from 2000 to 2007. J Clin Microbiol 48(8):2968–2971. doi:10.1128/JCM.01615-09
    • (2010) J Clin Microbiol , vol.48 , Issue.8 , pp. 2968-2971
    • Le Hello, S.1    Watson, M.2    Levy, M.3    Marcon, S.4    Brown, M.5    Yvon, J.F.6    Missotte, I.7    Garin, B.8
  • 39
    • 84937810661 scopus 로고    scopus 로고
    • Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance
    • Lemon JK, Miller MR, Weiser JN (2015) Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance. Infect Immun 83(8):3204–3212. doi:10.1128/IAI.00224-15
    • (2015) Infect Immun , vol.83 , Issue.8 , pp. 3204-3212
    • Lemon, J.K.1    Miller, M.R.2    Weiser, J.N.3
  • 40
    • 0030219032 scopus 로고    scopus 로고
    • Sequence variation in the Streptococcus pneumoniae pneumolysin gene affecting haemolytic activity and electrophoretic mobility of the toxin
    • Lock RA, Zhang QY, Berry AM, Paton JC (1996) Sequence variation in the Streptococcus pneumoniae pneumolysin gene affecting haemolytic activity and electrophoretic mobility of the toxin. Microb Pathog 21(2):71–83. doi:10.1006/mpat.1996.0044
    • (1996) Microb Pathog , vol.21 , Issue.2 , pp. 71-83
    • Lock, R.A.1    Zhang, Q.Y.2    Berry, A.M.3    Paton, J.C.4
  • 43
    • 84857681753 scopus 로고    scopus 로고
    • Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages
    • Marriott HM, Gascoyne KA, Gowda R, Geary I, Nicklin MJ, Iannelli F, Pozzi G, Mitchell TJ, Whyte MK, Sabroe I, Dockrell DH (2012) Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages. Infect Immun 80(3):1140-1149. doi:10.1128/IAI.05697-11
    • (2012) Infect Immun , vol.80 , Issue.3 , pp. 1140-1149
    • Marriott, H.M.1    Gascoyne, K.A.2    Gowda, R.3    Geary, I.4    Nicklin, M.J.5    Iannelli, F.6    Pozzi, G.7    Mitchell, T.J.8    Whyte, M.K.9    Sabroe, I.10    Dockrell, D.H.11
  • 44
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F, Burns K, Tschopp J (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10(2):417–426
    • (2002) Mol Cell , vol.10 , Issue.2 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 45
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440(7081):237–241. doi:10.1038/nature04516
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 48
    • 77952903334 scopus 로고    scopus 로고
    • Streptococcus pneumoniae: Virulence factors and variation
    • Mitchell AM, Mitchell TJ (2010) Streptococcus pneumoniae: virulence factors and variation. Clin Microbiol Infect 16(5):411–418. doi:10.1111/j.1469-0691.2010.03183.x
    • (2010) Clin Microbiol Infect , vol.16 , Issue.5 , pp. 411-418
    • Mitchell, A.M.1    Mitchell, T.J.2
  • 49
    • 0025879875 scopus 로고
    • Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein
    • Mitchell TJ, Andrew PW, Saunders FK, Smith AN, Boulnois GJ (1991) Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein. Mol Microbiol 5(8):1883–1888
    • (1991) Mol Microbiol , vol.5 , Issue.8 , pp. 1883-1888
    • Mitchell, T.J.1    Rew, P.W.2    Saunders, F.K.3    Smith, A.N.4    Boulnois, G.J.5
  • 51
    • 4344699028 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae
    • Opitz B, Puschel A, Schmeck B, Hocke AC, Rosseau S, Hammerschmidt S, Schumann RR, Suttorp N, Hippenstiel S (2004) Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J Biol Chem 279(35):36426-36432. doi:10.1074/jbc.M403861200
    • (2004) J Biol Chem , vol.279 , Issue.35 , pp. 36426-36432
    • Opitz, B.1    Puschel, A.2    Schmeck, B.3    Hocke, A.C.4    Rosseau, S.5    Hammerschmidt, S.6    Schumann, R.R.7    Suttorp, N.8    Hippenstiel, S.9
  • 52
    • 77954468897 scopus 로고    scopus 로고
    • Innate immune recognition in infectious and noninfectious diseases of the lung
    • Opitz B, van Laak V, Eitel J, Suttorp N (2010) Innate immune recognition in infectious and noninfectious diseases of the lung. Am J Respir Crit Care Med 181(12):1294–1309. doi:10.1164/rccm.200909-1427SO
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.12 , pp. 1294-1309
    • Opitz, B.1    Van Laak, V.2    Eitel, J.3    Suttorp, N.4
  • 54
    • 0028819622 scopus 로고
    • Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia
    • Rubins JB, Charboneau D, Paton JC, Mitchell TJ, Andrew PW, Janoff EN (1995) Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia. J Clin Investig 95 (1):142–150. doi:10.1172/JCI117631
    • (1995) J Clin Investig , vol.95 , Issue.1 , pp. 142-150
    • Rubins, J.B.1    Charboneau, D.2    Paton, J.C.3    Mitchell, T.J.4    Rew, P.W.5    Janoff, E.N.6
  • 56
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J (2010) The inflammasomes. Cell 140(6):821–832. doi:10.1016/j.cell.2010.01.040
    • (2010) Cell , vol.140 , Issue.6 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 58
    • 42149118561 scopus 로고    scopus 로고
    • Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: A novel function of pneumolysin in caspase-1 activation
    • Shoma S, Tsuchiya K, Kawamura I, Nomura T, Hara H, Uchiyama R, Daim S, Mitsuyama M (2008) Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation. Infect Immun 76(4):1547–1557. doi:10.1128/IAI.01269-07
    • (2008) Infect Immun , vol.76 , Issue.4 , pp. 1547-1557
    • Shoma, S.1    Tsuchiya, K.2    Kawamura, I.3    Nomura, T.4    Hara, H.5    Uchiyama, R.6    Daim, S.7    Mitsuyama, M.8
  • 59
    • 84945272221 scopus 로고    scopus 로고
    • Mechanisms of bacterial colonization of the respiratory tract
    • Siegel SJ, Weiser JN (2015) Mechanisms of bacterial colonization of the respiratory tract. Annu Rev Microbiol 69:425–444. doi:10.1146/annurev-micro-091014-104209
    • (2015) Annu Rev Microbiol , vol.69 , pp. 425-444
    • Siegel, S.J.1    Weiser, J.N.2
  • 61
  • 62
    • 70350498834 scopus 로고    scopus 로고
    • Pathogenesis, treatment, and prevention of pneumococcal pneumonia
    • van der Poll T, Opal SM (2009) Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 374(9700):1543–1556. doi:10.1016/S0140-6736(09)61114-4
    • (2009) Lancet , vol.374 , Issue.9700 , pp. 1543-1556
    • Van Der Poll, T.1    Opal, S.M.2
  • 63
    • 84898749740 scopus 로고    scopus 로고
    • NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia
    • van Lieshout MH, Scicluna BP, Florquin S, van der Poll T (2014) NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia. Am J Respir Cell Mol Biol 50 (4):699–712. doi:10.1165/rcmb.2013-0015OC
    • (2014) Am J Respir Cell Mol Biol , vol.50 , Issue.4 , pp. 699-712
    • Van Lieshout, M.H.1    Scicluna, B.P.2    Florquin, S.3    Van Der Poll, T.4
  • 64
    • 84863599129 scopus 로고    scopus 로고
    • Impact of pneumococcal microbial surface components recognizing adhesive matrix molecules on colonization
    • Voss S, Gamez G, Hammerschmidt S (2012) Impact of pneumococcal microbial surface components recognizing adhesive matrix molecules on colonization. Mol Oral Microbiol 27 (4):246–256. doi:10.1111/j.2041-1014.2012.00654.x
    • (2012) Mol Oral Microbiol , vol.27 , Issue.4 , pp. 246-256
    • Voss, S.1    Gamez, G.2    Hammerschmidt, S.3
  • 65
    • 34047259058 scopus 로고    scopus 로고
    • Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps
    • Wartha F, Beiter K, Albiger B, Fernebro J, Zychlinsky A, Normark S, Henriques-Normark B (2007) Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cell Microbiol 9(5):1162–1171. doi:10.1111/j.1462-5822.2006.00857.x
    • (2007) Cell Microbiol , vol.9 , Issue.5 , pp. 1162-1171
    • Wartha, F.1    Beiter, K.2    Albiger, B.3    Fernebro, J.4    Zychlinsky, A.5    Normark, S.6    Henriques-Normark, B.7
  • 67
    • 0036840362 scopus 로고    scopus 로고
    • Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis
    • Wellmer A, Zysk G, Gerber J, Kunst T, Von Mering M, Bunkowski S, Eiffert H, Nau R (2002) Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis. Infect Immun 70(11):6504–6508
    • (2002) Infect Immun , vol.70 , Issue.11 , pp. 6504-6508
    • Wellmer, A.1    Zysk, G.2    Gerber, J.3    Kunst, T.4    Von Mering, M.5    Bunkowski, S.6    Eiffert, H.7    Nau, R.8
  • 70


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.