NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 4, 2014, Pages 699-712

  Van Lieshout, Miriam H ^a,b   Scicluna, Brendon P ^a,b   Florquin, Sandrine ^b   Van Der Poll, Tom ^a,b  

^a Center of Infection and Immunity   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Adaptor apoptosis associated speck like protein containing a caspase activation and recruitment domain; Inflammasome; Nod like receptor family, pyrin domain containing 3; Pulmonary infection; Transcriptional response

Indexed keywords

ALPHA INTEGRIN; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CASPASE ACTIVATION AND RECRUITMENT DOMAIN; CRYOPYRIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INFLAMMASOME; INTEGRIN ALPHA M; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL LOAD; BLOOD CULTURE; CONTROLLED STUDY; CYTOKINE RESPONSE; FEMALE; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; LETHALITY; LUNG; LUNG HOMOGENATE; MORTALITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPLEEN; STREPTOCOCCUS PNEUMONIA;

ADAPTIVE IMMUNITY; ANIMALS; CARRIER PROTEINS; CYTOKINES; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; INFLAMMASOMES; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS; TRANSCRIPTOME;

EID: 84898749740     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0015OC     Document Type: Article

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