메뉴 건너뛰기




Volumn 34, Issue 7, 2006, Pages 1947-1954

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia

Author keywords

Acute lung injury; Endothelial permeability; Isolated mouse lung; Pneumococcal pneumonia; Pneumolysin; Pulmonary hypertension

Indexed keywords

PNEUMOLYSIN; RECOMBINANT PROTEIN; VIRULENCE FACTOR;

EID: 33745629065     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000220496.48295.A9     Document Type: Article
Times cited : (111)

References (48)
  • 1
    • 0036724321 scopus 로고    scopus 로고
    • Severe community-acquired pneumonia: Use of intensive care services and evaluation of American and British Thoracic Society Diagnostic criteria
    • Angus DC, Marrie TJ, Obrosky DS, et al: Severe community-acquired pneumonia: Use of intensive care services and evaluation of American and British Thoracic Society Diagnostic criteria. Am J Respir Crit Care Med 2002; 166:717-723
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 717-723
    • Angus, D.C.1    Marrie, T.J.2    Obrosky, D.S.3
  • 2
    • 0036062153 scopus 로고    scopus 로고
    • Community-acquired pneumonia in Europe: Causative pathogens and resistance patterns
    • Woodhead M: Community-acquired pneumonia in Europe: Causative pathogens and resistance patterns. Eur Respir J Suppl 2002; 36:20s-27s.
    • (2002) Eur Respir J Suppl , vol.36
    • Woodhead, M.1
  • 3
    • 0032827342 scopus 로고    scopus 로고
    • Pneumococcal pneumonia: Epidemiology and clinical features
    • Marrie TJ: Pneumococcal pneumonia: Epidemiology and clinical features. Semin Respir Infect 1999; 14:227-236
    • (1999) Semin Respir Infect , vol.14 , pp. 227-236
    • Marrie, T.J.1
  • 4
    • 0347364864 scopus 로고    scopus 로고
    • Community-acquired pneumonia
    • File TM: Community-acquired pneumonia. Lancet 2003; 362:1991-2001
    • (2003) Lancet , vol.362 , pp. 1991-2001
    • File, T.M.1
  • 5
    • 0036100216 scopus 로고    scopus 로고
    • The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection
    • Cockeran R, Anderson R, Feldman C: The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection. Curr Opin Infect Dis 2002; 15:235-239
    • (2002) Curr Opin Infect Dis , vol.15 , pp. 235-239
    • Cockeran, R.1    Anderson, R.2    Feldman, C.3
  • 6
    • 8144228074 scopus 로고    scopus 로고
    • The role of pneumolysin in pneumococcal pneumonia and meningitis
    • Hirst RA, Kadioglu A, O'Callaghan C, et al: The role of pneumolysin in pneumococcal pneumonia and meningitis. Clin Exp Immunol 2004; 138:195-201
    • (2004) Clin Exp Immunol , vol.138 , pp. 195-201
    • Hirst, R.A.1    Kadioglu, A.2    O'Callaghan, C.3
  • 7
    • 0034971094 scopus 로고    scopus 로고
    • Pneumococcal virulence factors: Structure and function
    • Jedrzejas MJ: Pneumococcal virulence factors: Structure and function. Microbiol Mol Biol Rev 2001; 65:187-207
    • (2001) Microbiol Mol Biol Rev , vol.65 , pp. 187-207
    • Jedrzejas, M.J.1
  • 8
    • 0033866076 scopus 로고    scopus 로고
    • Virulence factors and the pathogenesis of disease caused by Streptococcus pneumoniae
    • Mitchell TJ: Virulence factors and the pathogenesis of disease caused by Streptococcus pneumoniae. Res Microbiol 2000; 151:413-419
    • (2000) Res Microbiol , vol.151 , pp. 413-419
    • Mitchell, T.J.1
  • 9
    • 0029917088 scopus 로고    scopus 로고
    • The contribution of pneumolysin to the pathogenicity of Streptococcus pneumoniae
    • Paton JC: The contribution of pneumolysin to the pathogenicity of Streptococcus pneumoniae. Trends Microbiol 1996; 4:103-106
    • (1996) Trends Microbiol , vol.4 , pp. 103-106
    • Paton, J.C.1
  • 10
    • 0028819622 scopus 로고
    • Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia
    • Rubins JB, Charboneau D, Paton JC, et al: Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia. J Clin Invest 1995; 95:142-150
    • (1995) J Clin Invest , vol.95 , pp. 142-150
    • Rubins, J.B.1    Charboneau, D.2    Paton, J.C.3
  • 11
    • 0035282650 scopus 로고    scopus 로고
    • Protection against bacteremic pneumococcal infection by antibody to pneumolysin
    • Musher DM, Phan HM, Baughn RE: Protection against bacteremic pneumococcal infection by antibody to pneumolysin. J Infect Dis 2001; 183:827-830
    • (2001) J Infect Dis , vol.183 , pp. 827-830
    • Musher, D.M.1    Phan, H.M.2    Baughn, R.E.3
  • 12
    • 0028924974 scopus 로고
    • A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice
    • Benton KA, Everson MP, Briles DE: A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice. Infect Immun 1995; 63:448-455
    • (1995) Infect Immun , vol.63 , pp. 448-455
    • Benton, K.A.1    Everson, M.P.2    Briles, D.E.3
  • 13
    • 0026624724 scopus 로고
    • Toxicity of pneumolysin to pulmonary endothelial cells in vitro
    • Rubins JB, Duane PG, Charboneau D, et al: Toxicity of pneumolysin to pulmonary endothelial cells in vitro. Infect Immun 1992; 60:1740-1746
    • (1992) Infect Immun , vol.60 , pp. 1740-1746
    • Rubins, J.B.1    Duane, P.G.2    Charboneau, D.3
  • 14
    • 0027457731 scopus 로고
    • Toxicity of pneumolysin to pulmonary alveolar epithelial cells
    • Rubins JB, Duane PG, Clawson D, et al: Toxicity of pneumolysin to pulmonary alveolar epithelial cells. Infect Immun 1993; 61:1352-1358
    • (1993) Infect Immun , vol.61 , pp. 1352-1358
    • Rubins, J.B.1    Duane, P.G.2    Clawson, D.3
  • 15
    • 0037103529 scopus 로고    scopus 로고
    • Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro
    • Cockeran R, Durandt C, Feldman C, et al: Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. J Infect Dis 2002; 186:562-565
    • (2002) J Infect Dis , vol.186 , pp. 562-565
    • Cockeran, R.1    Durandt, C.2    Feldman, C.3
  • 16
    • 0025879875 scopus 로고
    • Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein
    • Mitchell TJ, Andrew PW, Saunders FK, et al: Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein. Mol Microbiol 1991; 5:1883-1888
    • (1991) Mol Microbiol , vol.5 , pp. 1883-1888
    • Mitchell, T.J.1    Andrew, P.W.2    Saunders, F.K.3
  • 17
    • 0035059186 scopus 로고    scopus 로고
    • Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils
    • Cockeran R, Steel HC, Mitchell TJ, et al: Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils. Infect Immun 2001; 69:3494-3496
    • (2001) Infect Immun , vol.69 , pp. 3494-3496
    • Cockeran, R.1    Steel, H.C.2    Mitchell, T.J.3
  • 18
    • 0035865826 scopus 로고    scopus 로고
    • Proinflammatory interactions of pneumolysin with human neutrophils
    • Cockeran R, Theron AJ, Steel HC, et al: Proinflammatory interactions of pneumolysin with human neutrophils. J Infect Dis 2001; 183:604-611
    • (2001) J Infect Dis , vol.183 , pp. 604-611
    • Cockeran, R.1    Theron, A.J.2    Steel, H.C.3
  • 19
    • 0027273245 scopus 로고
    • Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs
    • Walmrath D, Scharmann M, Konig R, et al: Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs. J Appl Physiol 1993; 74:1972-1980
    • (1993) J Appl Physiol , vol.74 , pp. 1972-1980
    • Walmrath, D.1    Scharmann, M.2    Konig, R.3
  • 20
    • 0030833341 scopus 로고    scopus 로고
    • Synergism between endotoxin priming and exotoxin challenge in provoking severe vascular leakage in rabbit lungs
    • Schutte H, Rosseau S, Czymek R, et al: Synergism between endotoxin priming and exotoxin challenge in provoking severe vascular leakage in rabbit lungs. Am J Respir Crit Care Med 1997; 156:819-824
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 819-824
    • Schutte, H.1    Rosseau, S.2    Czymek, R.3
  • 21
    • 0028170176 scopus 로고
    • Endotoxin "priming" potentiates lung vascular abnormalities in response to Escherichia coli hemolysin: An example of synergism between endo- and exotoxin
    • Walmrath D, Ghofrani HA, Rosseau S, et al: Endotoxin "priming" potentiates lung vascular abnormalities in response to Escherichia coli hemolysin: an example of synergism between endo- and exotoxin. J Exp Med 1994; 180:1437-1443
    • (1994) J Exp Med , vol.180 , pp. 1437-1443
    • Walmrath, D.1    Ghofrani, H.A.2    Rosseau, S.3
  • 22
    • 19944422390 scopus 로고    scopus 로고
    • Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor
    • Schmeck B, Zahlten J, Moog K, et al: Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. J Biol Chem 2004; 279:53241-53247
    • (2004) J Biol Chem , vol.279 , pp. 53241-53247
    • Schmeck, B.1    Zahlten, J.2    Moog, K.3
  • 23
    • 4344699028 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae
    • Opitz B, Puschel A, Schmeck B, et al: Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J Biol Chem 2004; 279:36426-36432
    • (2004) J Biol Chem , vol.279 , pp. 36426-36432
    • Opitz, B.1    Puschel, A.2    Schmeck, B.3
  • 24
    • 0034871504 scopus 로고    scopus 로고
    • Fas/Fas ligand system mediates epithelial injury, but not pulmonary host defenses, in response to inhaled bacteria
    • Matute-Bello G, Frevert CW, Liles WC, et al: Fas/Fas ligand system mediates epithelial injury, but not pulmonary host defenses, in response to inhaled bacteria. Infect Immun 2001; 69:5768-5776
    • (2001) Infect Immun , vol.69 , pp. 5768-5776
    • Matute-Bello, G.1    Frevert, C.W.2    Liles, W.C.3
  • 25
    • 0033968726 scopus 로고    scopus 로고
    • Host cellular immune response to pneumococcal lung infection in mice
    • Kadioglu A, Gingles NA, Grattan K, et al: Host cellular immune response to pneumococcal lung infection in mice. Infect Immun 2000; 68:492-501
    • (2000) Infect Immun , vol.68 , pp. 492-501
    • Kadioglu, A.1    Gingles, N.A.2    Grattan, K.3
  • 26
    • 20944438000 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: Role in endothelial hyperpermeability
    • Seybold J, Thomas D, Witzenrath M, et al: Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: Role in endothelial hyperpermeability. Blood 2005; 105:3569-3576
    • (2005) Blood , vol.105 , pp. 3569-3576
    • Seybold, J.1    Thomas, D.2    Witzenrath, M.3
  • 27
    • 0031919456 scopus 로고    scopus 로고
    • Hyperventilation induces release of cytokines from perfused mouse lung
    • von Bethmann AN, Brasch F, Nusing R, et al: Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med 1998; 157:263-272
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 263-272
    • Von Bethmann, A.N.1    Brasch, F.2    Nusing, R.3
  • 28
    • 0027524269 scopus 로고
    • Molecular analysis of the pathogenicity of Streptococcus pneumoniae: The role of pneumococcal proteins
    • Paton JC, Andrew PW, Boulnois GJ, et al: Molecular analysis of the pathogenicity of Streptococcus pneumoniae: The role of pneumococcal proteins. Annu Rev Microbiol 1993; 47:89-115
    • (1993) Annu Rev Microbiol , vol.47 , pp. 89-115
    • Paton, J.C.1    Andrew, P.W.2    Boulnois, G.J.3
  • 29
    • 0032954805 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
    • Folz RJ, Abushamaa AM, Suliman HB: Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. J Clin Invest 1999; 103:1055-1066
    • (1999) J Clin Invest , vol.103 , pp. 1055-1066
    • Folz, R.J.1    Abushamaa, A.M.2    Suliman, H.B.3
  • 30
    • 0037019988 scopus 로고    scopus 로고
    • Adrenomedullin reduces endothelial hyperpermeability
    • Hippenstiel S, Witzenrath M, Schmeck B, et al: Adrenomedullin reduces endothelial hyperpermeability. Circ Res 2002; 91:618-625
    • (2002) Circ Res , vol.91 , pp. 618-625
    • Hippenstiel, S.1    Witzenrath, M.2    Schmeck, B.3
  • 31
    • 0027195164 scopus 로고
    • Role of phosphodiesterases in the regulation of endothelial permeability in vitro
    • Suttorp N, Weber U, Welsch T, et al: Role of phosphodiesterases in the regulation of endothelial permeability in vitro. J Clin Invest 1993; 91:1421-1428
    • (1993) J Clin Invest , vol.91 , pp. 1421-1428
    • Suttorp, N.1    Weber, U.2    Welsch, T.3
  • 32
    • 0027754169 scopus 로고
    • A morphological biosensor for mammalian cells
    • Giaever I, Keese CR: A morphological biosensor for mammalian cells. Nature 1993; 366:591-592
    • (1993) Nature , vol.366 , pp. 591-592
    • Giaever, I.1    Keese, C.R.2
  • 33
    • 0030838457 scopus 로고    scopus 로고
    • Mechanisms of ionomycin-induced endothelial cell barrier dysfunction
    • Garcia JG, Schaphorst KL, Shi S, et al: Mechanisms of ionomycin-induced endothelial cell barrier dysfunction. Am J Physiol 1997; 273:L172-L184
    • (1997) Am J Physiol , vol.273
    • Garcia, J.G.1    Schaphorst, K.L.2    Shi, S.3
  • 34
    • 0026738687 scopus 로고
    • Electrical method for detection of endothelial cell shape change in real time: Assessment of endothelial barrier function
    • Tiruppathi C, Malik AB, Del Vecchio PJ, et al: Electrical method for detection of endothelial cell shape change in real time: Assessment of endothelial barrier function. Proc Natl Acad Sci U S A 1992; 89:7919-7923
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7919-7923
    • Tiruppathi, C.1    Malik, A.B.2    Del Vecchio, P.J.3
  • 35
    • 0345085543 scopus 로고    scopus 로고
    • Rapid and reliable identification of Streptococcus pneumoniae isolates by pneumolysin-mediated agglutination
    • Cima-Cabal MD, Vazquez F, de los Toros JR, et al: Rapid and reliable identification of Streptococcus pneumoniae isolates by pneumolysin-mediated agglutination. J Clin Microbiol 1999; 37:1964-1966
    • (1999) J Clin Microbiol , vol.37 , pp. 1964-1966
    • Cima-Cabal, M.D.1    Vazquez, F.2    De Los Toros, J.R.3
  • 36
    • 0035135293 scopus 로고    scopus 로고
    • Comparison of different detection methods in quantitative microdensitometry
    • Ermert L, Hocke AC, Duncker HR, et al: Comparison of different detection methods in quantitative microdensitometry. Am J Pathol 2001; 158:407-417
    • (2001) Am J Pathol , vol.158 , pp. 407-417
    • Ermert, L.1    Hocke, A.C.2    Duncker, H.R.3
  • 37
    • 0029986122 scopus 로고    scopus 로고
    • Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia
    • Rubins JB, Charboneau D, Fasching C, et al: Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia. Am J Respir Crit Care Med 1996; 153:1339-1346
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1339-1346
    • Rubins, J.B.1    Charboneau, D.2    Fasching, C.3
  • 38
    • 0037378079 scopus 로고    scopus 로고
    • Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin
    • Jounblat R, Kadioglu A, Mitchell TJ, et al: Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin. Infect Immun 2003; 71:1813-1819
    • (2003) Infect Immun , vol.71 , pp. 1813-1819
    • Jounblat, R.1    Kadioglu, A.2    Mitchell, T.J.3
  • 39
    • 0026261690 scopus 로고
    • Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo
    • Feldman C, Munro NC, Jeffery PK, et al: Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo. Am J Respir Cell Mol Biol 1991; 5:416-423
    • (1991) Am J Respir Cell Mol Biol , vol.5 , pp. 416-423
    • Feldman, C.1    Munro, N.C.2    Jeffery, P.K.3
  • 40
    • 0036138321 scopus 로고    scopus 로고
    • Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice
    • Rijneveld AW, van den Dobbelsteen GP, Florquin S, et al: Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice. J Infect Dis 2002; 185:123-126
    • (2002) J Infect Dis , vol.185 , pp. 123-126
    • Rijneveld, A.W.1    Van Den Dobbelsteen, G.P.2    Florquin, S.3
  • 41
    • 3142754927 scopus 로고    scopus 로고
    • Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space
    • Maus UA, Srivastava M, Paton JC, et al: Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space. J Immunol 2004; 173:1307-1312
    • (2004) J Immunol , vol.173 , pp. 1307-1312
    • Maus, U.A.1    Srivastava, M.2    Paton, J.C.3
  • 42
    • 0035139915 scopus 로고    scopus 로고
    • Pneumolysin is the main inducer of cytotoxicity to brain microvascular endothelial cells caused by Streptococcus pneumoniae
    • Zysk G, Schneider-Wald BK, Hwang JH, et al: Pneumolysin is the main inducer of cytotoxicity to brain microvascular endothelial cells caused by Streptococcus pneumoniae. Infect Immun 2001; 69:845-852
    • (2001) Infect Immun , vol.69 , pp. 845-852
    • Zysk, G.1    Schneider-Wald, B.K.2    Hwang, J.H.3
  • 43
    • 0029165459 scopus 로고
    • Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
    • Cundell DR, Gerard NP, Gerard C, et al: Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 1995; 377:435-438
    • (1995) Nature , vol.377 , pp. 435-438
    • Cundell, D.R.1    Gerard, N.P.2    Gerard, C.3
  • 44
    • 0026522415 scopus 로고
    • Induction of severe vascular leakage by low doses of Escherichia coli hemolysin in perfused rabbit lungs
    • Ermert L, Rousseau S, Schutte H, et al: Induction of severe vascular leakage by low doses of Escherichia coli hemolysin in perfused rabbit lungs. Lab Invest 1992; 66:362-369
    • (1992) Lab Invest , vol.66 , pp. 362-369
    • Ermert, L.1    Rousseau, S.2    Schutte, H.3
  • 45
    • 0029858026 scopus 로고    scopus 로고
    • Endothelial adherens junctions: Implications in the control of vascular permeability and angiogenesis
    • Dejana E: Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis. J Clin Invest 1996; 98:1949-1953
    • (1996) J Clin Invest , vol.98 , pp. 1949-1953
    • Dejana, E.1
  • 46
    • 13044264471 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo
    • Corada M, Mariotti M, Thurston G, et al: Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A 1999; 96:9815-9820
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9815-9820
    • Corada, M.1    Mariotti, M.2    Thurston, G.3
  • 47
    • 0029981294 scopus 로고    scopus 로고
    • Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization
    • Rabiet MJ, Plantier JL, Rival Y, et al: Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler Thromb Vasc Biol 1996; 16:488-496
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 488-496
    • Rabiet, M.J.1    Plantier, J.L.2    Rival, Y.3
  • 48
    • 0032834765 scopus 로고    scopus 로고
    • Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions
    • Andriopoulou P, Navarro P, Zanetti A, et al: Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions. Arterioscler Thromb Vasc Biol 1999; 19:2286-2297
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2286-2297
    • Andriopoulou, P.1    Navarro, P.2    Zanetti, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.