Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice

Journal of Clinical Investigation

Volumn 121, Issue 9, 2011, Pages 3666-3676

  Davis, Kimberly M ^a   Nakamura, Shigeki ^a,b   Weiser, Jeffrey N ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHEMOKINE RECEPTOR CCR2; CUTANEOUS T CELL ATTRACTING CHEMOKINE; LYSOZYME; PEPTIDOGLYCAN; PNEUMOLYSIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COLONIZATION; CELL MIGRATION; CONTROLLED STUDY; CYTOSOL; DATA ANALYSIS; EX VIVO STUDY; EXPRESSION VECTOR; GENE EXPRESSION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STREPTOCOCCUS PNEUMONIAE;

ADAPTIVE IMMUNITY; ANIMALS; CHEMOKINE CCL2; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MURAMIDASE; NOD2 SIGNALING ADAPTOR PROTEIN; PEPTIDOGLYCAN; PHAGOCYTES; PNEUMOCOCCAL INFECTIONS; RECEPTORS, CCR2; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTOR 2;

EID: 80052352663     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI57761     Document Type: Article

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