메뉴 건너뛰기




Volumn 10, Issue 8, 2015, Pages

Serotype 1 and 8 pneumococci evade sensing by inflammasomes in human lung tissue

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; CYTOKINE; INFLAMMASOME; INTERLEUKIN 1BETA; PNEUMOLYSIN; VIRULENCE FACTOR; BACTERIAL PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN;

EID: 84943279632     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137108     Document Type: Article
Times cited : (33)

References (53)
  • 1
    • 40949162838 scopus 로고    scopus 로고
    • The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease
    • 18340341
    • Kadioglu A, Weiser JN, Paton JC, Andrew PW (2008) The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol 6:288-301. doi: 10.1038/nrmicro1871 PMID: 18340341
    • (2008) Nat Rev Microbiol , vol.6 , pp. 288-301
    • Kadioglu, A.1    Weiser, J.N.2    Paton, J.C.3    Andrew, P.W.4
  • 2
    • 84858297649 scopus 로고    scopus 로고
    • Recognition of Streptococcus pneumoniae by the innate immune system
    • 22212419
    • Koppe U, Suttorp N, Opitz B (2012) Recognition of Streptococcus pneumoniae by the innate immune system. Cell Microbiol 14:460-466. doi: 10.1111/j.1462-5822.2011.01746.x PMID: 22212419
    • (2012) Cell Microbiol , vol.14 , pp. 460-466
    • Koppe, U.1    Suttorp, N.2    Opitz, B.3
  • 3
    • 70350498834 scopus 로고    scopus 로고
    • Pathogenesis, treatment, and prevention of pneumococcal pneumonia
    • 19880020
    • Van Der Poll T, Opal SM (2009) Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 374:1543-1556. doi: 10.1016/S0140-6736 (09) 61114-4 PMID: 19880020
    • (2009) Lancet , vol.374 , pp. 1543-1556
    • Van Der Poll, T.1    Opal, S.M.2
  • 4
    • 66349135616 scopus 로고    scopus 로고
    • Pneumococcal serotypes and mortality following invasive pneumococcal disease: A population-based cohort study
    • 19468297
    • Harboe ZB, Thomsen RW, Riis A, Valentiner-Branth P, Christensen JJ, et al. (2009) Pneumococcal serotypes and mortality following invasive pneumococcal disease: a population-based cohort study. PLoS Med 6:e1000081. doi: 10.1371/journal.pmed.1000081 PMID: 19468297
    • (2009) PLoS Med , vol.6 , pp. e1000081
    • Harboe, Z.B.1    Thomsen, R.W.2    Riis, A.3    Valentiner-Branth, P.4    Christensen, J.J.5
  • 5
    • 77955978715 scopus 로고    scopus 로고
    • Association of serotype with risk of death due to pneumococcal pneumonia: A meta-analysis
    • 20715907
    • Weinberger DM, Harboe ZB, Sanders EA, Ndiritu M, Klugman KP, et al. (2010) Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis 51:692-699. doi: 10.1086/655828 PMID: 20715907
    • (2010) Clin Infect Dis , vol.51 , pp. 692-699
    • Weinberger, D.M.1    Harboe, Z.B.2    Sanders, E.A.3    Ndiritu, M.4    Klugman, K.P.5
  • 6
    • 77957836354 scopus 로고    scopus 로고
    • Influence of pneumococcal serotype group on outcome in adults with bacteraemic pneumonia
    • 20150202
    • Lujan M, Gallego M, Belmonte Y, Fontanals D, Valles J, et al. (2010) Influence of pneumococcal serotype group on outcome in adults with bacteraemic pneumonia. Eur Respir J 36:1073-1079. doi: 10. 1183/09031936.00176309 PMID: 20150202
    • (2010) Eur Respir J , vol.36 , pp. 1073-1079
    • Lujan, M.1    Gallego, M.2    Belmonte, Y.3    Fontanals, D.4    Valles, J.5
  • 7
    • 32044471320 scopus 로고    scopus 로고
    • Clonal and capsular types decide whether pneumococci will act as a primary or opportunistic pathogen
    • 16421787
    • Sjostrom K, Spindler C, Ortqvist A, Kalin M, Sandgren A, et al. (2006) Clonal and capsular types decide whether pneumococci will act as a primary or opportunistic pathogen. Clin Infect Dis 42:451-459. PMID: 16421787
    • (2006) Clin Infect Dis , vol.42 , pp. 451-459
    • Sjostrom, K.1    Spindler, C.2    Ortqvist, A.3    Kalin, M.4    Sandgren, A.5
  • 8
  • 9
    • 30744464885 scopus 로고    scopus 로고
    • Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin
    • 16390963
    • Kirkham LA, Jefferies JM, Kerr AR, Jing Y, Clarke SC, et al. (2006) Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin. J Clin Microbiol 44:151-159. PMID: 16390963
    • (2006) J Clin Microbiol , vol.44 , pp. 151-159
    • Kirkham, L.A.1    Jefferies, J.M.2    Kerr, A.R.3    Jing, Y.4    Clarke, S.C.5
  • 10
    • 77955438285 scopus 로고    scopus 로고
    • Invasive serotype 1 Streptococcus pneumoniae outbreaks in the South Pacific from 2000 to 2007
    • 20534799
    • Le Hello S, Watson M, Levy M, Marcon S, Brown M, et al. (2010) Invasive serotype 1 Streptococcus pneumoniae outbreaks in the South Pacific from 2000 to 2007. J Clin Microbiol 48:2968-2971. doi: 10. 1128/JCM.01615-09 PMID: 20534799
    • (2010) J Clin Microbiol , vol.48 , pp. 2968-2971
    • Le Hello, S.1    Watson, M.2    Levy, M.3    Marcon, S.4    Brown, M.5
  • 11
    • 84925229741 scopus 로고    scopus 로고
    • Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak
    • 24666470
    • Staples M, Graham RM, Jennison AV, Ariotti L, Hicks V, et al. (2015) Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak. Epidemiol Infect 143:325-333. doi: 10. 1017/S0950268814000648 PMID: 24666470
    • (2015) Epidemiol Infect , vol.143 , pp. 325-333
    • Staples, M.1    Graham, R.M.2    Jennison, A.V.3    Ariotti, L.4    Hicks, V.5
  • 12
    • 84903820284 scopus 로고    scopus 로고
    • Trends in serotypes and sequence types among cases of invasive pneumococcal disease in Scotland, 1999-2010
    • 23806244
    • Lamb KE, Flasche S, Diggle M, Inverarity D, Greenhalgh D, et al. (2014) Trends in serotypes and sequence types among cases of invasive pneumococcal disease in Scotland, 1999-2010. Vaccine 32:4356-4363. doi: 10.1016/j.vaccine.2013.05.079 PMID: 23806244
    • (2014) Vaccine , vol.32 , pp. 4356-4363
    • Lamb, K.E.1    Flasche, S.2    Diggle, M.3    Inverarity, D.4    Greenhalgh, D.5
  • 13
    • 69249085390 scopus 로고    scopus 로고
    • Clonal structure and 21-year evolution of Streptococcus pneumoniae serotype 1 isolates in northern Spain
    • 19702591
    • Marimon JM, Ercibengoa M, Alonso M, Zubizarreta M, Perez-Trallero E (2009) Clonal structure and 21-year evolution of Streptococcus pneumoniae serotype 1 isolates in northern Spain. Clin Microbiol Infect 15:875-877. doi: 10.1111/j.1469-0691.2009.02883.x PMID: 19702591
    • (2009) Clin Microbiol Infect , vol.15 , pp. 875-877
    • Marimon, J.M.1    Ercibengoa, M.2    Alonso, M.3    Zubizarreta, M.4    Perez-Trallero, E.5
  • 14
    • 77952903334 scopus 로고    scopus 로고
    • Streptococcus pneumoniae: Virulence factors and variation
    • 20132250
    • Mitchell AM, Mitchell TJ (2010) Streptococcus pneumoniae: virulence factors and variation. Clin Microbiol Infect 16:411-418. doi: 10.1111/j.1469-0691.2010.03183.x PMID: 20132250
    • (2010) Clin Microbiol Infect , vol.16 , pp. 411-418
    • Mitchell, A.M.1    Mitchell, T.J.2
  • 15
    • 0033612389 scopus 로고    scopus 로고
    • Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae
    • 10367893
    • Gilbert RJ, Jimenez JL, Chen S, Tickle IJ, Rossjohn J, et al. (1999) Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae. Cell 97:647-655. PMID: 10367893
    • (1999) Cell , vol.97 , pp. 647-655
    • Gilbert, R.J.1    Jimenez, J.L.2    Chen, S.3    Tickle, I.J.4    Rossjohn, J.5
  • 16
    • 84901044466 scopus 로고    scopus 로고
    • Incomplete pneumolysin oligomers form membrane pores
    • 24759615
    • Sonnen AF, Plitzko JM, Gilbert RJ (2014) Incomplete pneumolysin oligomers form membrane pores. Open Biol 4:140044. doi: 10.1098/rsob.140044 PMID: 24759615
    • (2014) Open Biol , vol.4 , pp. 140044
    • Sonnen, A.F.1    Plitzko, J.M.2    Gilbert, R.J.3
  • 17
    • 84887137603 scopus 로고    scopus 로고
    • Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms
    • 24023386
    • Shak JR, Ludewick HP, Howery KE, Sakai F, Yi H, et al. (2013) Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms. MBio 4:e00655-00613. doi: 10.1128/mBio. 00655-13 PMID: 24023386
    • (2013) MBio , vol.4 , pp. e00655-e00613
    • Shak, J.R.1    Ludewick, H.P.2    Howery, K.E.3    Sakai, F.4    Yi, H.5
  • 18
    • 0036263426 scopus 로고    scopus 로고
    • Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type
    • 12010976
    • Kadioglu A, Taylor S, Iannelli F, Pozzi G, Mitchell TJ, et al. (2002) Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type. Infect Immun 70:2886-2890. PMID: 12010976
    • (2002) Infect Immun , vol.70 , pp. 2886-2890
    • Kadioglu, A.1    Taylor, S.2    Iannelli, F.3    Pozzi, G.4    Mitchell, T.J.5
  • 19
    • 0028819622 scopus 로고
    • Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia
    • 7814608
    • Rubins JB, Charboneau D, Paton JC, Mitchell TJ, Andrew PW, et al. (1995) Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia. J Clin Invest 95:142-150. PMID: 7814608
    • (1995) J Clin Invest , vol.95 , pp. 142-150
    • Rubins, J.B.1    Charboneau, D.2    Paton, J.C.3    Mitchell, T.J.4    Andrew, P.W.5
  • 20
    • 0029016207 scopus 로고
    • The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumococcus
    • 7797901
    • Canvin JR, Marvin AP, Sivakumaran M, Paton JC, Boulnois GJ, et al. (1995) The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumococcus. J Infect Dis 172:119-123. PMID: 7797901
    • (1995) J Infect Dis , vol.172 , pp. 119-123
    • Canvin, J.R.1    Marvin, A.P.2    Sivakumaran, M.3    Paton, J.C.4    Boulnois, G.J.5
  • 21
    • 34548497122 scopus 로고    scopus 로고
    • Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks
    • 17703426
    • Jefferies JM, Johnston CH, Kirkham LA, Cowan GJ, Ross KS, et al. (2007) Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks. J Infect Dis 196:936-944. PMID: 17703426
    • (2007) J Infect Dis , vol.196 , pp. 936-944
    • Jefferies, J.M.1    Johnston, C.H.2    Kirkham, L.A.3    Cowan, G.J.4    Ross, K.S.5
  • 22
    • 0030219032 scopus 로고    scopus 로고
    • Sequence variation in the Streptococcus pneumoniae pneumolysin gene affecting haemolytic activity and electrophoretic mobility of the toxin
    • 8844651
    • Lock RA, Zhang QY, Berry AM, Paton JC (1996) Sequence variation in the Streptococcus pneumoniae pneumolysin gene affecting haemolytic activity and electrophoretic mobility of the toxin. Microb Pathog 21:71-83. PMID: 8844651
    • (1996) Microb Pathog , vol.21 , pp. 71-83
    • Lock, R.A.1    Zhang, Q.Y.2    Berry, A.M.3    Paton, J.C.4
  • 23
    • 79251515144 scopus 로고    scopus 로고
    • Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
    • 21085613
    • McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, et al. (2010) Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. PLoS Pathog 6:e1001191. doi: 10.1371/journal.ppat.1001191 PMID: 21085613
    • (2010) PLoS Pathog , vol.6 , pp. e1001191
    • McNeela, E.A.1    Burke, A.2    Neill, D.R.3    Baxter, C.4    Fernandes, V.E.5
  • 24
    • 79960408020 scopus 로고    scopus 로고
    • The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia
    • 21646297
    • Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, et al. (2011) The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J Immunol 187:434-440. doi: 10.4049/jimmunol.1003143 PMID: 21646297
    • (2011) J Immunol , vol.187 , pp. 434-440
    • Witzenrath, M.1    Pache, F.2    Lorenz, D.3    Koppe, U.4    Gutbier, B.5
  • 25
    • 80555133274 scopus 로고    scopus 로고
    • Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
    • 21957143
    • Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, et al. (2011) Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection. J Immunol 187:4890-4899. doi: 10.4049/jimmunol.1100381 PMID: 21957143
    • (2011) J Immunol , vol.187 , pp. 4890-4899
    • Fang, R.1    Tsuchiya, K.2    Kawamura, I.3    Shen, Y.4    Hara, H.5
  • 26
    • 81455154929 scopus 로고    scopus 로고
    • The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
    • 22003197
    • Hoegen T, Tremel N, Klein M, Angele B, Wagner H, et al. (2011) The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J Immunol 187:5440-5451. doi: 10.4049/jimmunol.1100790 PMID: 22003197
    • (2011) J Immunol , vol.187 , pp. 5440-5451
    • Hoegen, T.1    Tremel, N.2    Klein, M.3    Angele, B.4    Wagner, H.5
  • 27
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • 20303873
    • Schroder K, Tschopp J (2010) The inflammasomes. Cell 140:821-832. doi: 10.1016/j.cell.2010.01. 040 PMID: 20303873
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 28
    • 77954468897 scopus 로고    scopus 로고
    • Innate immune recognition in infectious and noninfectious diseases of the lung
    • 20167850
    • Opitz B, Van Laak V, Eitel J, Suttorp N (2010) Innate immune recognition in infectious and noninfectious diseases of the lung. Am J Respir Crit Care Med 181:1294-1309. doi: 10.1164/rccm.200909-1427SO PMID: 20167850
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 1294-1309
    • Opitz, B.1    Van Laak, V.2    Eitel, J.3    Suttorp, N.4
  • 29
    • 0035500644 scopus 로고    scopus 로고
    • TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia
    • 11673538
    • Rijneveld AW, Florquin S, Branger J, Speelman P, Van Deventer SJ, et al. (2001) TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia. J Immunol 167:5240-5246. PMID: 11673538
    • (2001) J Immunol , vol.167 , pp. 5240-5246
    • Rijneveld, A.W.1    Florquin, S.2    Branger, J.3    Speelman, P.4    Van Deventer, S.J.5
  • 30
    • 0036135576 scopus 로고    scopus 로고
    • IL-18 improves the early antimicrobial host response to pneumococcal pneumonia
    • 11751983
    • Lauw FN, Branger J, Florquin S, Speelman P, Van Deventer SJ, et al. (2002) IL-18 improves the early antimicrobial host response to pneumococcal pneumonia. J Immunol 168:372-378. PMID: 11751983
    • (2002) J Immunol , vol.168 , pp. 372-378
    • Lauw, F.N.1    Branger, J.2    Florquin, S.3    Speelman, P.4    Van Deventer, S.J.5
  • 31
    • 68149125263 scopus 로고    scopus 로고
    • Pneumococcal interaction with human dendritic cells: Phagocytosis, survival, and induced adaptive immune response are manipulated by PavA
    • 19570831
    • Noske N, Kammerer U, Rohde M, Hammerschmidt S (2009) Pneumococcal interaction with human dendritic cells: phagocytosis, survival, and induced adaptive immune response are manipulated by PavA. J Immunol 183:1952-1963. doi: 10.4049/jimmunol.0804383 PMID: 19570831
    • (2009) J Immunol , vol.183 , pp. 1952-1963
    • Noske, N.1    Kammerer, U.2    Rohde, M.3    Hammerschmidt, S.4
  • 32
    • 20244373759 scopus 로고    scopus 로고
    • PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation
    • 15845469
    • Pracht D, Elm C, Gerber J, Bergmann S, Rohde M, et al. (2005) PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun 73:2680-2689. PMID: 15845469
    • (2005) Infect Immun , vol.73 , pp. 2680-2689
    • Pracht, D.1    Elm, C.2    Gerber, J.3    Bergmann, S.4    Rohde, M.5
  • 33
    • 84856063664 scopus 로고    scopus 로고
    • Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells
    • 22276187
    • Eitel J, Meixenberger K, Van Laak C, Orlovski C, Hocke A, et al. (2012) Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells. PLoS One 7:e30379. doi: 10.1371/journal.pone.0030379 PMID: 22276187
    • (2012) PLoS One , vol.7 , pp. e30379
    • Eitel, J.1    Meixenberger, K.2    Van Laak, C.3    Orlovski, C.4    Hocke, A.5
  • 34
    • 84871238582 scopus 로고    scopus 로고
    • Streptococcus pneumoniaeinduced regulation of cyclooxygenase-2 in human lung tissue
    • 22441740
    • Szymanski KV, Toennies M, Becher A, Fatykhova D, N'Guessan PD, et al. (2012) Streptococcus pneumoniaeinduced regulation of cyclooxygenase-2 in human lung tissue. Eur Respir J 40:1458-1467. doi: 10.1183/09031936.00186911 PMID: 22441740
    • (2012) Eur Respir J , vol.40 , pp. 1458-1467
    • Szymanski, K.V.1    Toennies, M.2    Becher, A.3    Fatykhova, D.4    N'Guessan, P.D.5
  • 35
    • 84869025948 scopus 로고    scopus 로고
    • Influenza A viruses target type II pneumocytes in the human lung
    • 22829640
    • Weinheimer VK, Becher A, Tonnies M, Holland G, Knepper J, et al. (2012) Influenza A viruses target type II pneumocytes in the human lung. J Infect Dis 206:1685-1694. doi: 10.1093/infdis/jis455 PMID: 22829640
    • (2012) J Infect Dis , vol.206 , pp. 1685-1694
    • Weinheimer, V.K.1    Becher, A.2    Tonnies, M.3    Holland, G.4    Knepper, J.5
  • 37
    • 0030666371 scopus 로고    scopus 로고
    • Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form
    • 9182756
    • Rossjohn J, Feil SC, McKinstry WJ, Tweten RK, Parker MW (1997) Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form. Cell 89:685-692. PMID: 9182756
    • (1997) Cell , vol.89 , pp. 685-692
    • Rossjohn, J.1    Feil, S.C.2    McKinstry, W.J.3    Tweten, R.K.4    Parker, M.W.5
  • 38
    • 84860771820 scopus 로고    scopus 로고
    • SPAdes: A new genome assembly algorithm and its applications to single-cell sequencing
    • 22506599
    • Bankevich A, Nurk S, Antipov D, Gurevich AA, Dvorkin M, et al. (2012) SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J Comput Biol 19:455-477. doi: 10.1089/cmb.2012.0021 PMID: 22506599
    • (2012) J Comput Biol , vol.19 , pp. 455-477
    • Bankevich, A.1    Nurk, S.2    Antipov, D.3    Gurevich, A.A.4    Dvorkin, M.5
  • 39
    • 77949515650 scopus 로고    scopus 로고
    • R2Cat: Synteny plots and comparative assembly
    • 20015948
    • Husemann P, Stoye J (2010) r2cat: synteny plots and comparative assembly. Bioinformatics 26:570-571. doi: 10.1093/bioinformatics/btp690 PMID: 20015948
    • (2010) Bioinformatics , vol.26 , pp. 570-571
    • Husemann, P.1    Stoye, J.2
  • 40
    • 0037561991 scopus 로고    scopus 로고
    • GenDB-an open source genome annotation system for prokaryote genomes
    • 12682369
    • Meyer F, Goesmann A, McHardy AC, Bartels D, Bekel T, et al. (2003) GenDB-an open source genome annotation system for prokaryote genomes. Nucleic Acids Res 31:2187-2195. PMID: 12682369
    • (2003) Nucleic Acids Res , vol.31 , pp. 2187-2195
    • Meyer, F.1    Goesmann, A.2    McHardy, A.C.3    Bartels, D.4    Bekel, T.5
  • 41
    • 17444405610 scopus 로고    scopus 로고
    • Structural basis of pore formation by the bacterial toxin pneumolysin
    • 15851031
    • Tilley SJ, Orlova EV, Gilbert RJ, Andrew PW, Saibil HR (2005) Structural basis of pore formation by the bacterial toxin pneumolysin. Cell 121:247-256. PMID: 15851031
    • (2005) Cell , vol.121 , pp. 247-256
    • Tilley, S.J.1    Orlova, E.V.2    Gilbert, R.J.3    Andrew, P.W.4    Saibil, H.R.5
  • 42
    • 70449727077 scopus 로고    scopus 로고
    • Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
    • 19805629
    • Lamkanfi M, Mueller JL, Vitari AC, Misaghi S, Fedorova A, et al. (2009) Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J Cell Biol 187:61-70. doi: 10.1083/jcb.200903124 PMID: 19805629
    • (2009) J Cell Biol , vol.187 , pp. 61-70
    • Lamkanfi, M.1    Mueller, J.L.2    Vitari, A.C.3    Misaghi, S.4    Fedorova, A.5
  • 43
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • 20023662
    • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J (2010) Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11:136-140. doi: 10.1038/ni.1831 PMID: 20023662
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 44
    • 84887146326 scopus 로고    scopus 로고
    • The novel human influenza A (H7N9) virus is naturally adapted to efficient growth in human lung tissue
    • 24105764
    • Knepper J, Schierhorn KL, Becher A, Budt M, Tonnies M, et al. (2013) The novel human influenza A (H7N9) virus is naturally adapted to efficient growth in human lung tissue. MBio 4:e00601-00613. doi: 10.1128/mBio.00601-13 PMID: 24105764
    • (2013) MBio , vol.4 , pp. e00601-e00613
    • Knepper, J.1    Schierhorn, K.L.2    Becher, A.3    Budt, M.4    Tonnies, M.5
  • 45
    • 84886258554 scopus 로고    scopus 로고
    • Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs
    • 24083868
    • Hocke AC, Becher A, Knepper J, Peter A, Holland G, et al. (2013) Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med 188:882-886. doi: 10.1164/rccm.201305-0954LE PMID: 24083868
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 882-886
    • Hocke, A.C.1    Becher, A.2    Knepper, J.3    Peter, A.4    Holland, G.5
  • 46
    • 84908409736 scopus 로고    scopus 로고
    • Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation
    • 25293758
    • Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, et al. (2014) Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation. MBio 5:e01710-01714. doi: 10.1128/mBio.01710-14 PMID: 25293758
    • (2014) MBio , vol.5 , pp. e01710-e01714
    • Bewley, M.A.1    Naughton, M.2    Preston, J.3    Mitchell, A.4    Holmes, A.5
  • 47
    • 84924173423 scopus 로고    scopus 로고
    • Degradation products of the extracellular pathogen Streptococcus pneumoniae access the cytosol via its pore-forming toxin
    • Lemon JK, Weiser JN (2015) Degradation products of the extracellular pathogen Streptococcus pneumoniae access the cytosol via its pore-forming toxin. MBio 6.
    • (2015) MBio , pp. 6
    • Lemon, J.K.1    Weiser, J.N.2
  • 48
    • 84905659601 scopus 로고    scopus 로고
    • The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent
    • 25105894
    • Harvey RM, Hughes CE, Paton AW, Trappetti C, Tweten RK, et al. (2014) The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. PLoS One 9:e103625. doi: 10.1371/journal.pone.0103625 PMID: 25105894
    • (2014) PLoS One , vol.9 , pp. e103625
    • Harvey, R.M.1    Hughes, C.E.2    Paton, A.W.3    Trappetti, C.4    Tweten, R.K.5
  • 49
    • 80053428072 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza
    • 21900488
    • Karlstrom A, Heston SM, Boyd KL, Tuomanen EI, McCullers JA (2011) Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza. J Infect Dis 204:1358-1366. doi: 10.1093/infdis/jir522 PMID: 21900488
    • (2011) J Infect Dis , vol.204 , pp. 1358-1366
    • Karlstrom, A.1    Heston, S.M.2    Boyd, K.L.3    Tuomanen, E.I.4    McCullers, J.A.5
  • 50
    • 84856020851 scopus 로고    scopus 로고
    • Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs
    • 22156592
    • Koppe U, Hogner K, Doehn JM, Muller HC, Witzenrath M, et al. (2012) Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J Immunol 188:811-817. doi: 10.4049/jimmunol.1004143 PMID: 22156592
    • (2012) J Immunol , vol.188 , pp. 811-817
    • Koppe, U.1    Hogner, K.2    Doehn, J.M.3    Muller, H.C.4    Witzenrath, M.5
  • 51
    • 80052352663 scopus 로고    scopus 로고
    • Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. Pneumoniae colonization in mice
    • 21841315
    • Davis KM, Nakamura S, Weiser JN (2011) Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. J Clin Invest 121:3666-3676. doi: 10.1172/JCI57761 PMID: 21841315
    • (2011) J Clin Invest , vol.121 , pp. 3666-3676
    • Davis, K.M.1    Nakamura, S.2    Weiser, J.N.3
  • 52
    • 4344699028 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae
    • 15215247
    • Opitz B, Puschel A, Schmeck B, Hocke AC, Rosseau S, et al. (2004) Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J Biol Chem 279:36426-36432. PMID: 15215247
    • (2004) J Biol Chem , vol.279 , pp. 36426-36432
    • Opitz, B.1    Puschel, A.2    Schmeck, B.3    Hocke, A.C.4    Rosseau, S.5
  • 53
    • 84922619235 scopus 로고    scopus 로고
    • The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response
    • 25658823
    • Rabes A, Zimmermann S, Reppe K, Lang R, Seeberger PH, et al. (2015) The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response. PLoS One 10:e0117022. doi: 10.1371/journal.pone.0117022 PMID: 25658823
    • (2015) PLoS One , vol.10 , pp. e0117022
    • Rabes, A.1    Zimmermann, S.2    Reppe, K.3    Lang, R.4    Seeberger, P.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.