Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

Cell Stem Cell

Volumn 19, Issue 1, 2016, Pages 23-37

  Woolthuis, Carolien M ^c   Stranahan, Alec W ^c   Park, Christopher Y ^c   Minhajuddin, Mohammad ^a   Gasparetto, Maura ^a   Stevens, Brett ^a   Pei, Shanshan ^a   Jordan, Craig T ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CSF2 PROTEIN; CYTARABINE; DASATINIB; DOXORUBICIN; ETOMOXIR; ETOPOSIDE; FIRTECAN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; IRINOTECAN; LIPOPROTEIN LIPASE; PROTEIN; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; FATTY ACID;

ACUTE MYELOID LEUKEMIA; ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLAST CELL CRISIS; CANCER CHEMOTHERAPY; CANCER STEM CELL; CELL SUBPOPULATION; CONTROLLED STUDY; ENERGY METABOLISM; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GENE EXPRESSION; GONADAL FAT; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRAPERITONEAL FAT; LEUKEMIA CELL; LEUKEMIC STEM CELL; LIPOLYSIS; METABOLISM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; SUBCUTANEOUS FAT; TUMOR MICROENVIRONMENT; UPREGULATION; ADAPTATION; ADIPOSE TISSUE; ANIMAL; BLAST CRISIS; C57BL MOUSE; CELL PROTECTION; DRUG EFFECTS; DRUG RESISTANCE; GONAD; INFLAMMATION; KNOCKOUT MOUSE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LEUKEMIA, MYELOID, ACUTE; OXIDATION REDUCTION REACTION; PATHOLOGY; TUMOR VOLUME;

ADAPTATION, PHYSIOLOGICAL; ADIPOSE TISSUE; ANIMALS; ANTIGENS, CD36; ANTINEOPLASTIC AGENTS; BLAST CRISIS; CYTOPROTECTION; DRUG RESISTANCE, NEOPLASM; ENERGY METABOLISM; FATTY ACIDS; GONADS; HUMANS; INFLAMMATION; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LEUKEMIA, MYELOID, ACUTE; LIPOLYSIS; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASTIC STEM CELLS; OXIDATION-REDUCTION; TUMOR BURDEN;

EID: 84978544485     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.06.001     Document Type: Article

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