Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo

PLoS Genetics

Volumn 11, Issue 2, 2015, Pages 1-24

  Kiraly, Orsolya ^a,b   Gong, Guanyu ^a   Olipitz, Werner ^a   Muthupalani, Sureshkumar ^c   Engelward, Bevin P ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULETIDE; DNA; METHYLNITROSOUREA; H2AX PROTEIN, MOUSE; HISTONE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CANCER RISK; CELL DIVISION; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA ALKYLATION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; EDEMA; FEMALE; FLUORESCENCE ANALYSIS; FLUORESCENT YELLOW DIRECT REPEAT ASSAY; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PANCREATITIS; PRECANCER; ANIMAL; COMPLICATION; DNA REPAIR; GENETICS; HUMAN; INFLAMMATION; MUTATION; NEOPLASMS; PANCREAS; PATHOLOGY; RISK FACTOR;

ANIMALIA; MUS;

ANIMALS; CELL PROLIFERATION; DNA DAMAGE; DNA REPAIR; HISTONES; HOMOLOGOUS RECOMBINATION; HUMANS; INFLAMMATION; MICE; MUTATION; NEOPLASMS; PANCREAS; RISK FACTORS;

EID: 84924408802     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004901     Document Type: Article

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